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The control of invasive Candida infection in very low birth weight infants by reduction in the use of 3rd generation cephalosporin

  • Chang, Yu Jin;Choi, Il Rak;Shin, Won Sub;Lee, Jang Hoon;Kim, Yun Kyung;Park, Moon Sung
    • Clinical and Experimental Pediatrics
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    • v.56 no.2
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    • pp.68-74
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    • 2013
  • Purpose: To evaluate the effectiveness of new management policies on the incidence of invasive Candida infections Methods: This observational study involved a retrospective analysis of the patients' medical records. In total, 99 very low birth weight infants, who were admitted to the neonatal intensive care unit at Ajou University Hospital from January 2010 to December 2011, were enrolled for the study. Period I, defined as the period before the revision of management policies, comprised 57 infants; whereas, period II, defined as the period after the implementation of new management policies, comprised 42 infants. The new management policies entailed a reduction in antibiotic and histamine type 2 receptor blocker (H2 blocker) use, duration of central venous catheterization, and duration of endotracheal intubation. Results: There was a significant overall decrease in the use of antibiotics including 3rd generation cephalosporin and H2 blockers (P<0.05), and a significantly lower incidence of invasive Candida infections in period II as compared to period I (0/42 vs. 6/57, respectively; P=0.037). Comparison between infants with invasive Candida infections (n=6) and those without (n=93) showed that gestational age (odds ratio [OR], 0.909; 95% confidence interval [CI], 0.829 to 0.996; P=0.042) and the duration of 3rd generation cephalosporin use (OR, 1.093; 95% CI, 1.009 to 1.183; P=0.029) were statistically significant risk factors. Conclusion: The new management policies effectively decreased overall use of antibiotics, especially 3rd generation cephalosporin, and H2 blockers, which led to a significantly lower incidence of invasive Candida infections.

Dilemma of a small dam with large basin area under climate change condition

  • Jeong-Hyeok Ma;Chulsang Yoo;Tae-Sup Yun;Dongwhi Jung
    • Computers and Concrete
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    • v.33 no.5
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    • pp.559-572
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    • 2024
  • Problems of under-sized dams (small dams with large basin area) could get worse under the global warming condition. This study evaluates the possible change of these problems with the Namgang Dam, an under-sized dam in Korea. For this purpose, first, this study simulates the dam inflow data using a rainfall-runoff model, which are then used as input for the reservoir operation. As a result, daily dam storage, dam release, and dam water supply are derived and compared for both past observed period (1973~2022) and future simulated period (2006~2099) based on the global warming scenarios. Summarizing the results are as follows. First, the inflow rate in the future is expected to be increased significantly. The maximum inflow could be twice of that observed in the past. As a result, it is also expected that the frequency of the water level reaching the high level is increasing. Also, the amount and frequency of dam release are to be increased in the future period. More seriously, this increase is expected to be concentrated on rather extreme cases with large dam release volume. Simply, the condition for flood protection in the downstream of the Namgang Dam is becoming worse and worse. Ironically, the severity of water shortage problem is also expected to become much worse. As the most extreme case, the frequency of no water supply was zero in the observed period, but in the future period, it becomes once every five years. Both the maximum consecutive shortage days and the total shortage volume are expected to become more than twice in the future period. To prevent or mitigate this coming problem of an under-sized dam, the only countermeasure at this moment seems to be its redevelopment. Simply a bigger dam with larger dam reservoir can handle this adverse effect more easily.

Effect of Hwangto, Illite, Oligosacharides, Charcoal powder and Chromium picolinate on the Growth Performance and Immunity in Eary Weaned Hanwoo Calves (한우 수송아지에 대한 황토, 일라이트, 올리고당, 활성탄 및 크롬 급여가 성장발육 및 면역기능에 미치는 영향)

  • Kang, S.W.;Cho, C.Y.;Kim, J.S.;Ahn, B.S.;Chung, H.Y.;Seo, K.H.
    • Journal of Animal Science and Technology
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    • v.44 no.5
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    • pp.531-540
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    • 2002
  • This study was conducted to examine the effect of Hwangto, Illite, and any other disease resistant materials as dietary supplements on the growth performance and immunity for growing period with 30 Hanwoo male calves weaned 75days in age. Feeding trial was conducted with 6 treatments(five heads/treatment), which were T1(Control), T2(Control + 2% Hwangto), T3(Control + 2% Illite), T4(Control + 0.04% Oligosacharides), T5(Control + 2% Charcoal powder) and T6(Control + 0.1% Chromium picolinate) for 120 days from three to seven months in age. The results obtained are summarized as follows; During the experimental period, average daily gains were 0.82 to 0.92kg, and were high in the order of T3, T6, T4, T5, T2 and T1. Especially the growth rate of calves for growing period was higher in Illite, chromium-picolinate and oligo- sacharides feeding groups than in any other groups. Average daily intakes and intake ratio to body weight of concentrates for 120days were 3.91 to 4.15kg(average 4.03kg) and 3.10 to 3.31% (average 3.21%), respectively. TDN intakes per kilogram gains were 3.20 to 3.57kg(average 3.35kg) and were smaller in the order of T5, T3, T6, T4, T2 and T1, respectively. Density of IgG in serum of calves measured by the IgG SDID Kit was 10.2 to 11.6mg/$m\ell$, and especially increase rate of IgG for experimental period was high in T3 and T5 by 6.9 and 2.8%, respectively. But incidence of disease was not found to be different by treatments. According to the above results it may be concluded that Illite is a sort of clay minerals increased the growth rate, feed efficiency and immunity of early weaned calves for growing period, but was not in unprocessed Hwangto.

Effects of Different Sources of Dietary Chromium on Growth, Blood Profiles and Carcass Traits in Growing-finishing Pigs

  • Park, J.K.;Lee, J.Y.;Chae, B.J.;Ohh, S.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.11
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    • pp.1547-1554
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    • 2009
  • This study was carried out to evaluate the effects of dietary supplementation of different sources of chromium on growth performance, blood profile and carcass trait in growing-finishing pigs. A total of 200 growing pigs (Landrace${\times}$Yorkshire)${\times}$Duroc, average initial weight 8.5 kg) were allotted to 5 treatments with 4 replicates per treatment and 10 pigs per replicate. Five treatments were designated as follows according to the source of chromium. i) Control (No chromium): corn-soybean meal based basal diet, ii) $CrCl_{3}$: control diet+200 ppb Cr as $CrCl_{3}$, iii) CrPic: control diet+200 ppb Cr as Cr picolinate, iv) CrMet-1: control diet+100 ppb Cr as Cr methionine, and v) CrMet-2: control diet+200 ppb Cr as Cr methionine. After the feeding trial, three pigs per replicate (12 pigs per treatment) were slaughtered for the evaluation of carcass traits. Average daily gain (ADG), average daily feed intake (ADFI), and feed: gain ratio (F/G) were not different (p>0.05) among dietary Cr sources. However, whole-period ADG of pigs fed CrPic, CrMet-1 and CrMet-2 diets was higher (p<0.05) than for the control diet. Nutrient digestibility was not different (p>0.05) among dietary Cr sources, but the nutrient digestibility of pigs fed CrPic, CrMet-1 and CrMet-2 diets was higher (p<0.05) than for the control diet. BUN level decreased with more magnitude (p<0.05) in pigs fed Cr during the 20 to 50 kg period. Although both serum cholesterol and triglyceride were different (p<0.05) among treatments, there was no consistent response that could be related to the dietary Cr sources regardless of growth phase. However, the overall data suggested that serum cholesterol level increased as BW of pigs increased. Blood total protein (TP) increased (p<0.05) in pigs fed Cr only during the 90-110 kg phase, and blood creatinine (Creat) level was higher in $CrCl_{3}$ and CrPic treatments than in the control only during the 90-110 kg phase. Backfat thickness was thinner (p<0.05) in pigs fed CrMet-2 than in the control treatment. Therefore, lean percentage was higher (p<0.05) in CrMet-2 than in control pigs. However, dressing percentage and Longissimus muscle area (LMA) were not different (p>0.05) among treatments. In conclusion, dietary supplementation of 200 ppb Cr, via either CrPic or CrMet, improved pig growth performance and nutrient digestibility. Moreover, dietary CrMet supplementation for the growing-finishing pig is evidently remarkable for improving both lean percentage of the carcass and backfat thickness.

Effect of the Mixture of Thrombin Powder and Gelfoam Powder on Control of Exposed Cancellous Bone Bleeding (Thrombin Powder와 Gelfoam Powder의 혼합물을 이용한 노출된 망상골면 출혈의 지혈효과)

  • Park, Sung Wan;Cho, Ha Young;Lee, Seung Myoung;Jeong, Seong Hun;Song, Jin Kyu;Jang, Suk Jung;Shin, Ho
    • Journal of Korean Neurosurgical Society
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    • v.29 no.5
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    • pp.664-667
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    • 2000
  • Objective : Excessive bleeding from the exposed cancellous bone surface may cause serious problem such as hematoma formation, infection, transfusion reaction during operation and postoperative period. There are several kinds of bleeding control agent on the cancellous bone surface including bone wax, gelatin sponge ($Gelfoam^{(R)}$), oxidized cellulose($Oxycel^{(R)}$, $Surgicel^{(R)}$), thrombin, microfibrillar collagen($Avitene^{(R)}$) etc. In the past, bone wax was used to control bone bleeding but it is associated with increased infection rate and fusion failure. Recently, gelfoam paste has been used to control cancellous bone bleeding. We controlled the cancellous bone bleeding with the mixture of gelfoam powder and thrombin powder. Material and Methods : Seventeen patients of posterior fusion on the 4 motion segments of thoracolumbar spine were selected to compare the result of bone bleeding control. In the test group of 9 patients, the cancellous bone bleeding was controlled with the mixture of Gelfoam and thrombin powder during operation. In the control group of 8 cases, no chemical hemostatic agent was used to manage the bone bleeding during operation. We calculated the total amount of bleeding from cancellous bone surface during and after operation in the two groups and compared their statistic significance of the result which was judged by student t-test. Results : The average amount of intraoperative bleeding was 1825ml in control group, 811ml in test group(p<0.01). The amount of postoperative bleeding was 943ml in control group and 812ml in test group, there were no significant difference in the amount of bleeding during postoperative period between two groups(p>0.5). Total amount of blood was decreased in as much as 1150ml in test group(p<0.01). Conclusion : We concluded that the application of the mixture of thrombin and gelfoam powder on the cancellous bone surface is the effective control method of cancellous bone bleeding for multilevel posterior spinal fusion.

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Effect of Maternal Undernutrition on the Growth and Composition of Young Rat Brain (분만전후의 어미쥐의 영양부족이 새끼쥐의 뇌성장발육과 조성에 미치는 영향)

  • Chang, Kyung-Ja;Choi, Hay-Mie
    • Journal of Nutrition and Health
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    • v.14 no.2
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    • pp.105-116
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    • 1981
  • A quantitative restriction of maternal diet without changes in quality of diet was given to the Sprague Dawley rats during the third week of gestation and lactation. Half the normal average daily intake of control group was given to deficient groups in this period. Female rats of control group were fed a commercial diet ad libitum throughout the experimental period. Dietary restriction started from birth to weaning in deficient I group and from the 15th day of gestation to weaning in deficient II group. Body and brain weight of offsprings of deficient groups were significantly lower than control group, but the ratios of brain weight to body weight in deficient groups were higher than the control group. Significant difference between deficient groups (I and II) was noticed at weaning. Brain DNA, RNA and total protein of offsprings of deficient groups were significantly lower than control group, but RNA/DNA, brain weight/DNA, and total protein/DNA show that cell number were more affected than the cell size by the maternal dietary restriction during the third week of gestation and lactation. Between the deficient groups, there was a significant difference in brain DNA and RNA, but no significant difference in total brain protein. (This research was supported in part by grant from the Ministry of Education.)

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Nutrient Intakes of Male College Combat Sport Athletes by Weight Control Status (남자 대학생 체급경기선수의 체중조절 군별 영양소 섭취 실태)

  • Kim, Ji Yeon;Lee, Ji Seon;Cho, Seong Suk;Park, Hyon;Kim, Kyung Won
    • Korean Journal of Community Nutrition
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    • v.22 no.6
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    • pp.495-506
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    • 2017
  • Objectives: Weight control practices are common in combat sport athletes. This study was performed to examine nutrient intakes of male college combat sport athletes (taekwondo, boxing, judo) by weight control (WC) status. Methods: Subjects were male combat sport athletes (n=90) from colleges in Gyeonggi Province. Survey was conducted during 2016. Questionnaire included general characteristics, weight control, and dietary intakes during the period of training, weight control, weigh-in ~ before competition and between competitions. Subjects were grouped into high- and normal WC groups. T-test, ${\chi}^2-test$, Fisher's exact test and ANCOVA were used to analyze the data. Results: During training, energy intake was 75.4% of EER and C:P:F ratio was 57.5:13.9:28.7. Iron and zinc intakes were different by WC groups (p<0.05). During weight control, energy intake was 44.7% of EER in normal WC and 30.5% in high WC group (p<0.05). C:P:F ratio was 69:11.1:19.5, and ratio from protein and fat was lower in the high WC group (p<0.05). Most nutrient intakes during weight control were less than 50% of 2015 KDRIs (RNI or AI), and intakes including thiamin (p<0.01), vitamin A, riboflavin, niacin, folate, calcium, potassium and zinc (p<0.05) were significantly lower in the high WC. Energy intake after weighing before the competition was 1,315 kcal, and energy (kcal/kg BW, p<0.05) and carbohydrate intakes (g/kg BW, p<0.01) were significantly higher in the high WC group. Energy intake between competitions was 691.1 kcal, with no difference by the WC group. Conclusions: Nutrients intakes of combat sport athletes were inadequate. Dietary intakes during weight control were much below than the KDRIs, especially in the high WC group. It is needed to develop nutrition education programs for combat sport athletes to avoid severe energy restrictions and to apply specific dietary guides to each period of training and weight control.

Control of Powdery Mildew of Pepper Using Culture Solutions of Chitinolytic Bacteria, Chromobacterium sp. and Lysobacter enzymogenes (키틴분해세균 Chrobacterium sp.와 Lysobacter enzymogenes의 배양액을 이용한 고추 흰가루병의 방제)

  • Seo, Chong-Chan;Jung, Hyun-Chae;Park, Seur-Kee
    • Research in Plant Disease
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    • v.13 no.1
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    • pp.40-44
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    • 2007
  • Powdery mildew of pepper is one of the most devastating diseases which is occurring all the year under greenhouse condition. In this study, control efficacy against powdery mildew was evaluated by mixed culture solutions of two chitinolytic bacteria, Lysobacter enzymogenenes strain C-3 and Chrornobacterium sp. strain C-61, cultivated in the chitin-supplemented medium. In all experiments, white powder on the reverse side of pepper leaves perfectly disappeared 3 days after application of mixed culture solutions. However, periods required for formation of new white powder on the same sites after application (control-lasting period) were largely differed according to environmental conditions. In particular, the control-lasting period was much longer when sprayed on 6 PM than 9 AM and especially, on rainy days than sunny days. This indicates that control efficacy of culture solution may be largely affected by environmental conditions after application. The undiluted culture solution resulted in a perfect control with control value more than 95% by application of 5-day-intervals under severely diseased field and 7-day-intervals under disease-started field. A ten-fold diluted product also showed control value more than 81% by application of the same method. These results suggest that this culture solution can be practically used to control powdery mildew disease in pepper plants.

The Factors Associated with Body Shape Control by Self-Estimated Figure among Female University Students (일부 여대생의 체형 타입과 관련된 요인에 관한 연구)

  • Choi, Do-Jeom;Lee, Byul-La;Lee, Eun-Sook
    • Journal of the East Asian Society of Dietary Life
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    • v.16 no.6
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    • pp.646-654
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    • 2006
  • This study was designed to examine body shape control and its related factors, including BMI(body mass index), desire for weight control, satisfaction with body shape, dissatisfaction with specific parts of body shape, starting period of concern about body shape, as well as experience, method, result, counsel, effort, expense and knowledge of body shape control. The survey was completed by 180 female university students in Gyeongsanbukdo through a self-administered questionnaire during September and October of 2006. The subjects were assigned to one of three groups based on self-estimated figure: 47.8% of the students estimated their figure as 'normal', while 38.3% of the students estimated themselves as 'thin' and 13.9% of the students as 'fat'. The results were as fellows. The mean age of the subjects was $19.45{\pm}1.67$ with a height and weight of $161.15{\pm}4.99cm$ and $52.63{\pm}10.78\;kg$, respectively. Their self-estimated figure was significantly related to BMI, desire for weight control, satisfaction, dissatisfaction with a specific part, and experience, counsel and effort in body shape control. This research suggests that students need to know how to properly control body shape in health and beauty.

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The Effects of Enterprise Resource Planning (ERP) Implementation on Corporate Performance (전사적 자원관리(ERP)의 도입효과에 관한 재무분석)

  • Lim, Chang-Woo;Lee, Seog-Hi
    • The Journal of Information Systems
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    • v.16 no.1
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    • pp.91-109
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    • 2007
  • This study investigates the extent to which the implementation of enterprise resource planning(ERP) systems enhance the corporate performance by examining financial variables of the implemented firms against those of the control fm. A total of 346 observations were obtained from 160 firms, 80 implemented firms and 80 control firms, for the period of 1998-2002. Results from the study partly support the assertion that ERP improves the full spectrum of business functions such as selling, marketing, purchasing, warehousing, accounting and human resources by tightly integrating enterprise-wise information databases. First the profitability of the implemented group was different from that of the control group. The indicator (dummy) variable was able to explain the differences in total cash flows between the implemented group fm and the control group firms. Second, ERP turned out In improve the efficiency in managing assets. The indicator variable has the power in explaining the differences in the amount of accounts receivables between the implemented group firms and the control group firms. Third, the product turnover ratio of the implemented group was different from that of the control group. Fourth, the average value added per employee and the net income per employee of the implemented group firms were greats- than those of the control group firms. Finally, the average magnitude of the administrative expenses of the implemented group firms was smaller than that of the control group firms.

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