• Proceedings of the KSAR Conference
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• 2003.06a
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• pp.21-21
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• 2003

Male germ cell apoptosis has been extensively explored in rodent. In contrast, very little is known about their susceptibility to apoptosis stimuli of developing germ cell stages at the time when germ cell depletion after busulfan treatment occurs. Furthermore, it is still unanswered how spermatogonial stem cells are resistant to busulfan treatment. We examined the change of gene expression in detail using cDNA microarray analysis of mouse testis treated with busulfan. A subtoxic dose of busulfan (40mg/kg of body weight) transiently increased 228 mRNA levels among of the 8000 genes analyzed. TagMan analysis confirmed that the mRNA levels such as defensive protein, support protein, enzymatic protein, transport protein, and hormonal protein were rapidly increased. These results were re-confirmed by real-time PCR analysis. However, the expression levels of these genes induced by busulfan treatment were significantly reduced in control testis, indicating that both of male germ cells and somatic cells after busulfan treatment induces self-defense mechanism for protection of testicular cell death. Among them, we conclude that defense proteins play a key role in testis injury induced by busulfan.

• Journal of Korean Association for Spatial Structures
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• v.20 no.3
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• pp.81-89
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• 2020

As the damage caused by earthquakes gradually increases, seismic retrofitting for existing public facilities has been implemented in Korea. Several types of structural analysis methods can be used to evaluate the seismic performance of structures. Among them, for nonlinear dynamic analysis, the hysteresis model must be carefully applied because it can significantly affect the behavior. In order to find a hysteresis model that predicts rational behavior, this study compared the experimental results and analysis results of the existing non-seismic reinforced concrete frames. For energy dissipation, the results were close to the experimental values in the order of Pivot, Concrete, Degrading, and Takeda models. The Concrete model underestimated the energy dissipation due to excessive pinching. In contrast, the other ones except the Pivot model showed the opposite results with relatively little pinching. In the load-displacement curves, the experimental and analysis results tended to be more similar when the column axial force was applied to columns.

• Journal of Power Electronics
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• v.13 no.5
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• pp.861-876
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• 2013

Instead of extracting every selected harmonic component, the current reference of selective active power filter (APF) can be also obtained by filtering out the fundamental component from distorted load current for computation efficiency. This type of mixed current reference contains kinds of harmonic components and easily involves noises. In this condition, selective harmonic compensation must be realized by the current controller. With regard that selectivity is the most significant feature of controller, this paper presents specific comparison analysis between two types of resonant controllers: proportional-resonant (PR) controller and vector-resonant (VR) controller. The comparison analysis covers the relations, performances, and stability of both controllers. Analysis results conclude that the poorer selectivity of the PR controller could be relatively improved, but limitations from system stability make the improvement hardly realized. By contrast, the VR controller exhibits excellent selectivity and is more suitable for selective APF with mixed current reference. Experimental results from laboratory prototype validate the reasonability of analysis. And the features of each resonant controller are concluded.

• Journal of Environmental Science International
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• v.14 no.5
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• pp.473-480
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• 2005

The cost of the construction and management of new apartment buildings was evaluated using a monetary analysis and an emergy concept to provide a new perspective regarding the housing policy of Korea. The systems of analyses were typical apartment buildings with an area of $76.03m^2$ per household in Korea built on the same size of land area. Three apartment buildings with different stories were evaluated and compared; 5-story, 15-story, and 20-story apartment buildings. The durable years of those apartments were assumed to be 40 years. The total cost of the construction and management of an apartment building was divided into three categories of construction, land purchase, and management. A 20-story apartment showed the highest cost and a 15-story apartment the lowest in the monetary cost analysis. In contrast, the emergy evaluation revealed a different pattern in the cost of construction and management, the cost increasing from a 5-story apartment to a 20-story one. This means that the higher the apartment constructed, the greater the cost in terms of real wealth. This result suggests that new evaluation methodologies like the emergy analysis should be used together with the monetary analysis to provide better insights on the national housing policy.

• Atmosphere
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• v.24 no.1
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• pp.77-87
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• 2014

The radar reflectivity is significantly affected by ground clutter, beam blockage, anomalous propagation (AP), birds, insects, chaff, etc. The quality of radar reflectivity is very important in quantitative precipitation estimation. Therefore, Weather Radar Center (WRC) of Korea Meteorological Administration (KMA) employed two quality control algorithms: 1) Open Radar Product Generator (ORPG) and 2) fuzzy quality control algorithm to improve quality of radar reflectivity. In this study, an occurrence of AP echoes and the performance of both quality control algorithms are investigated. Consequently, AP echoes frequently occur during the spring and fall seasons. Moreover, while the ORPG QC algorithm has the merit of removing non-precipitation echoes, such as AP echoes, it also removes weak rain echoes and snow echoes. In contrast, the fuzzy QC algorithm has the advantage of preserving snow echoes and weak rain echoes, but it eliminates the partial area of the contaminated echo, including the AP echoes.

• Journal of the Korean Society for Precision Engineering
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• v.27 no.8
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• pp.35-41
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• 2010

White Etching Layer(WEL) is a phenomenon that occurs on the surface of rail due to wheel/rail interactions such as excessive braking and acceleration. Rolling Contact Fatigue(RCF) cracks on the surface of rail have been found to be associated with WEL. In this study, we have investigated RCF damages of white etching layer using twin disc testing and fatigue analysis. These tests consist of wheel flat tests and rolling contact fatigue tests. WEL has been simulated by wheel flat test. It has been founded that the WEL with a bright featureless contrast is formed on the surface of specimen by etching. Rolling contact fatigue test was conducted by using flat specimens with the WEL generated by the wheel flat test. It has been observed that two types of cracks occur within the specimen. The contact fatigue test was simulated in 2D elastic-plastic FE simulations. Based on loading cycles obtained from the finite element analysis, the fatigue life analysis according to the thickness variation of WEL was carried out. The longest fatigue life was observed from the thickness of 20um.

• Journal of the Korean Society of Visualization
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• v.13 no.3
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• pp.15-19
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• 2015

We developed a high-throughput microscopy (HTM) method which enabled us to replace a conventional phase contrast microscopy (PCM) method that has been used as a standard analytical method for airborne asbestos. We could obtain the concentration of airborne asbestos fibers under detection limit by automated image processing and analysis using HTM method. Here we propose an improved image processing algorithm with variable parameters to enhance the accuracy of the HTM analysis. Since the variable parameters that compensate the difference of the brightness are applied to the individual images in our new image processing method, it is possible to enhance the accuracy of the automatic image analysis method for sample slides with low asbestos concentration that caused errors in binary image processing. We demonstrated that enumeration of fibers by improved image processing algorithm remarkably enhanced the accuracy of HTM analysis in comparison with PCM. The improved HTM method can be a potential alternative to conventional PCM.

• Korean Institute of Interior Design Journal
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• v.13 no.5
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• pp.173-180
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• 2004

The cultural identity of each nation has appeared as a major issue in this multi-cultural era, and needs to define It clearly through comparisons with other cultures have been raised. The purpose of this study is to figure out ‘similarity’ and ‘dissimilarity’ on design characteristics of traditional storage furniture in interior context of Korea, China and Japan. Comparative analysis of traditional furniture was conducted in two terms, in terms of inner space, first, spatial elevation and front patterns, second, flooring materials of the interior space and types of furniture legs. Result of first comparative analysis showed that composition of windows, one of the major decorative elements of interior space, positively influenced on furniture, and reflected unique patterns of each country. Second comparative analysis showed that structures and shapes of traditional furniture vary depending on flooring materials. As a result of it, Korean furniture has the structure of ‘punghyeol’ and Chinese furniture has the structure of ‘aja’ with ‘takni’ , a combination of legs. In contrast to the two countries, Japanese furniture has rarely legs. The result of analysis is expected to act a role of establishing the cultural identity of our own country.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5853-5860
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• 2014

Background: Methylenetetrahydrofolate (MTHFR) is the key enzyme of the folate metabolic pathway and several studies have pointed to association between the MTHFR C677T polymorphism and breast cancer risk. Although significant association was observed in some studies, in others no clear link could be established. Objective: A meta-analysis of published Asian case control studies was therefor carried out to shed further light on any C677T breast cancer association. Materials and Methods: PubMed, Springer Link, Google Scholar and Elsevier databases were searched for case control studies of associations between MTHFR C677T polymorphism and breast cancer risk. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association. A total of 36 studies including 8,040 cases and 10,008 controls were included in the present meta-analysis. Results: Overall, a significantly elevated breast cancer risk was associated with the T allele and TT genotype in homozygote comparison and dominant genetic models when all studies were pooled into the meta-analysis (T vs C (allele contrast model): OR=1,23, 95%CI=1.13-1.37, p=0.000 ; TT vs CC(homozygote model): OR=1.38, 95%CI=1.16-1.63, p=0.0003; TT+CT vs CC (dominant model): OR=1.12, 95%CI=1.01-1.23, p=0.02). Conclusions: The present meta-analysis strongly suggested a significant association between the MTHFR C677T polymorphism and risk of breast cancer in Asian populations.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.28 no.1
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• pp.75-82
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• 2020

To compare and analyze the differences between flight simulation and actual flight among 130 army helicopter pilot training subjects, the correlation analysis was performed first through t-testing and multiple regression analysis of individual characteristics and flight simulation and actual instrument flight training, which were analyzed significantly in the age (a3) and service classification (a5) of the six verification factors. This has been shown to be significant, with no difference between the flight simulator and the actual flight. Second, in order to study the correlation between aircraft types, the flight evaluation (v1) was analyzed as a dependent variable for the performance of the flight simulator (KUH: s2, UH60: s3, AH-1S: s5, UH-1H: s6), and the results of the multiple regression analysis of the flight simulator evaluation (s1) were analyzed, in contrast, as a dependent variable, and in conclusion, the training of the flight simulator provided statistical data on the possibility of replacing the actual flight training, which is thought to contribute to the orientation, budget reduction and aviation safety of the pilot training.