• Title/Summary/Keyword: contact effect

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Immunosuppressive effects and pathogenicity of a Korean isolate of reticuloendotheliosis virus in chickens (Reticuloendotheliosis virus의 닭에 대한 면역억제효과와 병원성)

  • Han, Myung-guk;Kim, Sun-joong
    • Korean Journal of Veterinary Research
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    • v.40 no.2
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    • pp.311-323
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    • 2000
  • Immunosuppressive effects of reticuloendotheliosis virus (REV) infection in chickens were investigated. Primary antibody responses to Newcastle disease virus (strain B1) and sheep red blood cells were significantly low in chickens inoculated with the local isolate 89-74 of REV compared to those of uninfected chickens. In chickens infected with REV strain T or 89-74, blastogenesis of spleen cells and peripheral blood lymphocytes (PBL) to concanavalin A (Con A) was severely suppressed. When specific pathogen free (SPF) chickens were inoculated with the isolate, the suppressive effect was observed up to 7 weeks of age while, in the contact infected chickens, the suppression was absent. Similar suppressive effects were observed in chickens inoculated with REV strain T at 2, 3 and 4 weeks of age. When spleen cells or PBL from uninfected chickens were co-cultured with spleen cells or PBL from chickens infected with REV at 1 day-old or 2 week-old, the blastogenesis of the normal cells was suppressed. The suppressive effect of PBL from REV-infected chickens on normal lymphocytes was abrogated by the treatment with trypsin. However the suppressive activity of the REV-infected PBL was not influenced at removing machrophage from the cell suspension by incubation in plastic petri dishes. In addition to the immunosuppression, chickens infected with the REV isolate showed abnormal feather development (nakanuke), anemia, paralysis and retarded growth. Three out of 11 chickens inoculated with the isolate at day-old died between 6 and 9 weeks of age by bacterial infections.

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A Study on Synthesis of Polyurethane/Functionalized Graphene Nanocomposites by In-situ Intercalation Method (In-situ 법에 의한 폴리우레탄/기능화 된 그래핀 나노복합체의 합성에 관한 연구)

  • Hwang, Soo-Ok;Lee, Byung-Hwan;Cho, Ur-Ryong
    • Elastomers and Composites
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    • v.47 no.3
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    • pp.238-245
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    • 2012
  • Graphene oxide was synthesized from natural graphite, and its surface was modified using diisocyanatodicyclohexylmethane( $H_{12}MDI$). Isocyanate-graphene sheet(i-RGO) was obtained by reduction of surface modified GO. To select nanofiller having good dispersion with polyurethane, GO, i-RGO, natural graphite and thermal reduced graphite were analyzed, and then i-RGO was selected as a suitable nanofiller. PU/i-RGO nanocomposite was synthesized with various i-RGO contents to estimate effect of reinforcement on nanocomposite. Thermal stability, hardness, contact angle were increased with i-RGO contents due to i-RGO characteristic and crosslink bridge effect. But, tensile strength and elongation were decreased at i-RGO contents more than the 4 wt%. This phenomenon was interpreted by the excess formation of crosslink bridge.

IN VITRO STUDY ON THE CYTOTOXICITY OF THE DIFFERENTLY STERILIZED DEMINERALIZED BONE POWDER (멸균방법에 따른 탈회동종골의 세포독성 여부에 관한 실험적 연구)

  • Woo, Ki-Sun;Yim, Chang-Joon;Kim, Se-Won;Kim, Jong-Yeo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.19 no.3
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    • pp.287-299
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    • 1997
  • Procurement, cutting, cleansing, freezing, freeze-drying, and demineralization of the allogeneic bone must be made under the germ-free stable condition without bacterial and/or viral contamination. Even thought the bone is procured under the germ free condition, we must have confidence on disinfection of all the solutions that come in contact with tissue during the whole procedure. Lots of antibacterial agents have been introduced for chemical sterilization. Recently ethylene oxide gas sterilization or radiation sterilization is frequently selected as a secendary sterilization procedure. The biological and biochemical response of the graft material differs with the type and concentration of the sterilizing agents, and various toxic reactions have been reported due to the graft material itself and the substance released by the chemicals. The authors conducted the Millipore filter test to observe the toxic effect on L929 fibroblasts according to the effect on activity of succinate dehydrogenase, during the secondary sterilization of the demineralized allogeneic bone powder with irradiation or ethylene oxide gas. The result were as follows : 1. Around the copper disk, positive control group, 10mm diameter discoloration was observed. 2. As same as the negative control group, the disk showed no discoloration. 3. The demineralized allogeneic bone which was sterilized with ethylene oxide gas or irradiation showed no cytotoxicity. 4. From this results, it is suggested that treatment with ethylene oxide gas or irradiation should be effective to sterilize the deminineralized allogeneic bone.

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The first photometric analysis of the close binary system NSVS 1461538

  • Kim, Hyoun-Woo;Kim, Chun-Hwey
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.1
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    • pp.41.2-41.2
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    • 2016
  • The follow-up BVRI photometric observations of NSVS 1461538, which was discovered as an $Algol/{\beta}$ Lyr eclipsing variable by Hoffman, Harrison & McNamara (2009), were performed for three years from 2011 to 2013 by using the 61-cm telescope and CCD cameras of Sobaeksan Optical Astronomy Observatory (SOAO). New light curves have deep depths both of the primary and secondary eclipses, rounded shapes outside eclipses and a strong O'Connell effect, indicating that NSVS 1461538 is a typical W UMa close binary system rather than an $Algol/{\beta}$ Lyr type binary star. A period study with all the timings shows that the orbital period may vary in a sinusoidal way with a period of about 5.6 yr and a small semi-amplitude of about 0.008 d. The cyclical period variation was interpreted as a light-time effect due to a tertiary body with a minimum mass of $0.66M{\odot}$. The first photometric solution with the Wilson-Devinney binary model shows that the system is a W-subtype contact binary with the mass ratio ($q=m_c/m_h$) of 3.46, orbit inclination of 85.6 deg and fill-out factor of 30%. From the existing empirical relationship between parameters, the absolute dimension was estimated. The masses and radii of the component stars are $0.28M{\odot}$ and $0.71R{\odot}$ for the less massive but hotter primary star, respectively, and $0.96M{\odot}$ and $1.21R{\odot}$ for the more massive secondary, respectively. Possible evolution of the system is discussed in the mass-radius and the mass-luminosity planes.

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The Effect of Stack Clamping Pressure on the Performance of a Miniature PEMFC Stack (소형 고분자 연료전지 스택의 체결압력에 따른 성능 특성)

  • Kim, Byung-Ju;Yim, Sung-Dae;Sohn, Young-Jun;Kim, Chang-Soo;Yang, Tae-Hyun;Kim, Young-Chai
    • Journal of Hydrogen and New Energy
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    • v.20 no.6
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    • pp.499-504
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    • 2009
  • The effect of gas diffusion layer (GDL) compression caused by different stack clamping pressures on fuel cell performance was experimentally studied in a miniature 5-cell proton exchange membrane fuel cell (PEMFC) stack. Three stacks with different GDL compressions, 15%, 35% and 50%, were prepared using SGL 10BC carbon fiber felt GDL and Gore 57 series MEA. The PEMFC stack performance and the stack stability were enhanced with increasing stack clamping pressure resulting in the best performance and stability for the stack with higher GDL compressions up to 50%. The excellent performance of the stack with high GDL compression was mainly due to the reduced contact resistance between GDL and bipolar plate in the stack, while reduced gas permeability of the excessively compressed GDL in the stack hardly affected the stack performance. The high stack clamping pressure also resulted in excessive GDL compression under the rib areas of bipolar plate and large GDL intrusion into the channels of the plate, which reduced the by-pass flow in the channels and increase gas pressure drop in the stack. It seems that these phenomena in the highly compressed stack enhance the water management in the stack and lead to the high stack stability.

Case Study of Workload Distribution Index for RTGC in Container Terminal Yard (컨테이너 터미널의 RTGC작업 분산지표 적용연구 - H사를 중심으로 -)

  • Shin, Chang-Hoon;Park, Jong-Won;Kwon, Min-Kyun;Shin, Jae-Young
    • Journal of Navigation and Port Research
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    • v.41 no.4
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    • pp.229-234
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    • 2017
  • Container terminal yards operate under a high degree of uncertainty as the contact point between inbound and outbound operations of vessels and external trucks. The layout, equipment operations. and job orders at the yards determine the efficacy and delays of the work, so many studies have investigated improvements in efficiency. H company, a container terminal operator developed an index called WDI to distribute work among RTGCs. The WDI is an indicator to prevent congestion in one place by equally distributing the work to each RTGC. This paper analyzes the effect of the WDI introduction and discusses the causes and results of the WDI introduction effect from quantitative and qualitative perspectives.

Implementation of Low Noise Current Sensor using Low Pass FIR Filter (저역통과 FIR필터를 이용한 저잡음 전류 센서 구현)

  • Kim, Jeong-Hwan;Lee, Seong-Jin;Choi, Yong-geon;Han, Seong-Gye;Kwon, Se-Ik;Kim, Nam-Ho
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.05a
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    • pp.499-502
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    • 2017
  • The needs of efficient electricity use and current measurement for electrical safety have been increased. Hence, the current sensor is used, especially non-contact current sensor which can measure the current without blocking the circuit using hall effect. However, the accurate measuring of the current sensor is inhibited due to the inflow of various noises in this current sensor. In this article, a stronger current sensor against the noise is proposed using low pass FIR filter to the existing current sensor. FIR filter was designed to block the range over the certain frequency at the output of the current sensor to eliminate the external noises, and so on. As a result, more accurate and close measurements were possible.

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System and method for detecting gas using smart-phone (스마트폰을 이용한 가스검출시스템 및 검출 방법연구)

  • Bang, Yong-Ki;Kang, Kyung-Sik
    • Journal of the Korea Safety Management & Science
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    • v.17 no.2
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    • pp.129-137
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    • 2015
  • This study is in regard to the gas detection system and gas detection method utilizing smart phone. This study includes; 1) the sensor module attached to the smart phone to detect and measure flammable gas or toxic gas; and 2) gas detection APP which is installed inside the smart phone and recognizes the user information and location information automatically by reading RFID tag indicating the user or the location to detect gas through the contact area where RFID and blue tooth reader is installed inside of the above mentioned smart phone, and then measures the combustible gas or toxic gas by operating above mentioned sensor module and obtains the data thus measured, and above mentioned smart phone is characterized by its transmission of the above mentioned user information, location information and measured data which are obtained by above mentioned gas detecting APP to operation server via communication network. With this, reliability for the location detecting gas by the user, the result of the measurement, etc. can be secured. Furthermore, this provides the effect of preventing artificial manipulation at the time of input which is associated with the identification of the user to be measured by utilizing removable sensor module and application or the mistake resulted from wrong input by the user. In addition, by transmitting the measured data from the sensor module carrying out gas detection to operation server, this provides the effect of making it possible to process the data thus collected to a specialized data for combustible gas or toxic gas.

Effect of etched microgrooves on hydrophilicity of titanium and osteoblast responses: A pilot study

  • Park, Jung-Ae;Lee, Sung-Bok Richard;Ahn, Su-Jin;Lee, Suk-Won
    • The Journal of Advanced Prosthodontics
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    • v.2 no.1
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    • pp.18-24
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    • 2010
  • PURPOSE. The aim of this pilot study was to investigate the effect of etched microgrooves on the hydrophilicity of Ti and osteoblast responses. MATERIAL AND METHODS. Microgrooves were applied on Ti to have 15 and $60{\mu}m$ width, and 3.5 and $10{\mu}m$ depth by photolithography, respectively. Further acid etching was applied to create Ti surfaces with etched microgrooves. Both smooth- and acid-etched Ti were used as the controls. The hydrophilicity of Ti was analyzed by determining contact angles. Cell proliferation and osteogenic activity of MC3T3 mouse preosteoblasts were analyzed by bromodeoxyuridine assay and alkaline phosphatase (ALP) activity test, respectively. One-way ANOVA, Pearson's correlation analysis and multiple regression analysis were used for statistics. RESULTS. Etched microgrooves significantly increased the hydrophilicity of Ti compared to the smooth Ti. $60{\mu}m$-wide etched microgrooves significantly enhanced cell proliferation, whereas the osteogenic activity showed statistically non-significant differences between groups. Result of the osteogenic activity significantly correlated with those of hydrophilicity and cell proliferation. Hydrophilicity was determined to be an influential factor on osteogenic activity. CONCLUSION. This study indicates that increase in hydrophilicity of Ti caused by etched microgrooves acts as an influential factor on osteogenic activity. However, statistically non-significant increase in the ALP activity suggests further investigation.

Surface Treatment of Air Gap Membrane Distillation (AGMD) Condensation Plates: Techniques and Influences on Module Performance

  • Harianto, Rachel Ananda;Aryapratama, Rio;Lee, Seockheon;Jo, Wonjin;Lee, Heon Ju
    • Applied Science and Convergence Technology
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    • v.23 no.5
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    • pp.248-253
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    • 2014
  • Air Gap Membrane Distillation (AGMD) is one of several technologies that can be used to solve problems fresh water availability. AGMD exhibits several advantages, including low conductive heat loss and higher thermal efficiency, due to the presence of an air gap between the membrane and condensation wall. A previous study by Bhardwaj found that the condensation surface properties (materials and contact angle) affected the total collected fresh water in the solar distillation process. However, the process condition differences between solar distillation and AGMD might result in different condensation phenomena. In contrast, N. Miljkovic showed that a hydrophobic surface has higher condensation heat transfer. Moreover, to the best of our knowledge, there is no study that investigates the effect of condensation surface properties in AGMD to overall process performance (i.e. flux and thermal efficiency). Thus, in this study, we treated the AGMD condensation surface to make it hydrophobic or hydrophilic. The condensation surface could be made hydrophilic by immersing and boiling plate in deionized (DI) water, which caused the formation of hydrophilic aluminum hydroxide (AlOOH) nanostructures. Afterwards, the treated plate was coated using hexamethyldisiloxane (HMDSO) through plasma-enhanced chemical vapor deposition (PECVD). The result indicated that condensation surface properties do not affect the permeate flux or thermal efficiency significantly. In general, the permeate flux and thermal efficiency for the treated plates were lower than those of the non-treated plate (pristine). However, at a 1 mm and 3 mm air gap, the treated plate outperformed the non-treated plate (pristine) in terms of permeate flux. Therefore, although surface wettability effect was not significant, it still provided a little influence.