• The Journal of Advanced Prosthodontics
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• 제13권1호
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• pp.46-54
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• 2021

Purpose. The design of the implant-abutment complex is thought to be responsible for marginal bone loss (MBL) and might affect the condition of the peri-implant tissues. This the present study aimed to evaluate the influence of the implant-abutment complex on MBL and the peri-implant tissues in partially edentulous patients treated with dental implants and determine the most advantageous design. Materials and Methods. A total of ninety-one endosseous implants with different designs of implant-abutment complex [tissue level-TL (n = 30), platform switch-PS (n = 18), and platform match-PM (n = 43)] were reviewed for MBL, Probing Pocket Depth (PPD) and Bleeding on Probing (BoP). MBL was calculated for first year of the insertion and the following years. Results. The median MBL for the PM implants (2.66 ± 1.67 mm; n = 43) in the first year was significantly higher than those for the other types (P=.033). The lowest rate of MBL (0.61 ± 0.44 mm; n = 18) was observed with PS implants (P=.000). The position of the crown-abutment border showed a statistically significant influence (P=.019) and a negative correlation (r=-0.395) on MBL. BoP was found significantly higher in PM implants (P=.006). The lowest BoP scores were detected in PS implants, but the difference was not significant (P=.523). The relation between PPD and connection type revealed no statistically significant influence (P>.05). Conclusion. Within the limitations of the present study, it may be concluded that PS implants seem to show better peri-implant soft tissue conditions and cause less MBL.

• Advances in concrete construction
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• 제11권1호
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• pp.33-43
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• 2021

A new type of composite insulated concrete sandwich wall (ICS-wall), which is composed of a triangle truss steel wire network, an insulating layer, and internal and external concrete layers, is proposed. To study the mechanical properties of this new ICS-wall, tensile, compression, and shearing tests were performed on 22 specimens and tensile strength and corrosion resistance tests on 6 triangle truss joints. The variables in these tests mainly include the insulating plate material, the thickness of the insulating plate, the vertical distance of the triangle truss framework, the triangle truss layout, and the connecting mode between the triangle truss and wall and the material of the triangle truss. Moreover, the failure mode, mechanical properties, and bearing capacity of the wall under tensile, shearing, and compression conditions were analyzed. Research results demonstrate that the concrete and insulating layer of the ICS-wall are pulling out, which is the main failure mode under tensile conditions. The ICS-wall, which uses a graphite polystyrene plate as the insulating layer, shows better tensile properties than the wall with an ordinary polystyrene plate. The tensile strength and bearing capacity of the wall can be improved effectively by strengthening the triangle truss connection and shortening the vertical distances of the triangle truss. The compression capacity of the wall is mainly determined by the compression capacity of concrete, and the bonding strength between the wall and the insulating plate is the main influencing factor of the shearing capacity of the wall. According to the tensile strength and corrosion resistance tests of Austenitic stainless steel, the bearing capacity of the triangle truss does not decrease after corrosion, indicating good corrosion resistance.

• 한국비블리아학회지
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• 제32권1호
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• pp.267-293
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• 2021

본 연구의 목적은 교과 교육과정과 연계할 수 있는 범교과 학습주제의 성취기준을 분석하고, 학교도서관에 활용할 수 있는 진로독서와 관련된 프로그램을 개발하고 적용하는 데 있다. 이러한 연구의 목적을 위해 첫째, 2015 개정 교육과정의 범교과 학습주제를 10개 주제로 범주화하고, 진로교육의 세부 내용요소를 통합적으로 다룰 수 있는 범교과 학습 활동을 통해 독서교육 프로그램과 연계하여 수업모형을 설계하였다. 둘째, 중학생 5개 반 137명을 대상으로 한 학기 동안 범교과 기반의 진로독서 수업모형을 통해 자기이해, 진로탐색, 진로설계 영역의 진로독서 수업을 실행하였다. 셋째, 연구의 분석을 위해 진로독서 평가 자료를 구축하여 분석하였으며 일화기록과 체크리스트의 다각적인 관찰과 실행연구를 수행하였다. 마지막으로 진로독서 스토리텔링과 흥미유형의 진로 멘토 중심 도서목록 자료를 제시하고, 학교 현장에서의 진로독서 교육 활동을 제안하였다.

• 한국기계가공학회지
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• 제21권3호
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• pp.56-62
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• 2022

The tank engine clutch flange constitutes a tank on which the engine and transmission of the tank are mounted. The engine clutch flange is fabricated using a difficult-to-cut material that exhibits high strength and hardness. It is difficult to process and requires considerable processing expertise. In addition, the engine clutch flange for the tank requires high machining precision because it is a system in which the connection is detachable. Because it requires high processing precision, the measurement of products equally important as processing. However, productivity is low owing to the significant amount of time required to measure each product using a three-dimensional coordinate measuring machine. Hence, this study is conducted to improve the productivity of the female tank engine clutch flange. Dedicated hobs and jigs are designed and manufactured to convert the existing end-mill cutting processing into hobbing cutting processing. An engine clutch for the tanks is manufactured using the manufactured dedicated hob and jig, and the shortening time is verified by measuring the processing time. In addition, a jig for inspection is designed and manufactured to measure the precision of the product. To verify the inspected product, the product precision is measured using a contact-type three-dimensional coordinate measuring machine and a surface roughness measuring instrument. The study confirmed that the productivity of the engine clutch flange product for tanks can be improved by simplifying the process, reducing the processing time, and simplifying product inspection.

• 한국학교수학회논문집
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• 제25권2호
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• pp.105-124
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• 2022

분수 나눗셈은 교육과정에 따른 교과서마다 문제 상황이나 해결 방법에서 변화가 있었고, 교과서 내용은 학생들의 학습에 직접 영향을 주기 때문에 중요하다. 본 연구에서는 우리나라의 최근 3개 교육과정과 그에 따른 교과서에 제시된 분수 나눗셈의 교육과정 성취기준, 수식 유형 및 문제 상황, 비표준 및 표준 알고리즘의 도입 과정을 분석하였다. 분석 결과, 교육과정 성취기준의 차이는 거의 없었으나, 교과서의 학년별 내용 제시에 변화가 있었다. 수식 유형에서는 교육과정별 교과서마다 차이가 있었고, 문제 상황은 다양해지는 변화가 나타났다. 해결 방법은 표준 알고리즘을 강조한 것에서 최근 교과서에서 비표준 알고리즘과 표준 알고리즘을 병행하는 방향으로 변화하였다. 제언으로 나눗셈 유형별로 내용을 세분화하기보다는 문제 상황별로 유목화할 수 있는 방안과 비표준 알고리즘과 표준 알고리즘의 연계 및 표준 알고리즘 도입 과정의 공통적 속성에 따라 일반화와 정당화를 추구하는 방안 마련이 필요함을 제시하였다.

• 한국수정란이식학회:학술대회논문집
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• 한국수정란이식학회 2002년도 국제심포지엄
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• pp.99-99
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• 2002

The hormone resistin is associated with typeII diabetes mellitus in rodent model. Resistin impairs glucose tolerance and insulin action. A new class of anti-diabetic drugs were called thiazolidinediones (TZDs) downregulates a resistin which is induced during adipocyte differentiation. But the connection between increased adiposity and resistin remains unknown. The objectives of this study was to clone a mouse resistin cDNA and to generate transgenic mice overexpressing mouse resistin gene. The 555 bp of mouse resistin was amplified from mob cDNAS by polymerase chain reaction (PCR) and cloned into pCR$\^$(R)/ 2.1 TOPO T-vector. Mouse resistin mRNA on the basis of Genbank sequence (acession no. AF323080). Then, the PCR product was cloned into pTargeT$\^$TM/ mammalian expression vector that has pCMV promoter and chimeric intron. Restriction enzyme analysis with BamH I and Not I was carried out to determine an orientation of the insert in the vector. The pCMV-mus/resistin gene was prepared from previous recombinant pTargeT$\^$TM/-mus/resistin by digestion of Bgl II, and has used for microinjection into pronuclei of one cell embryos. The microinjected embryos were transfered to pseudopregnant foster-mother. Mouse resistin expression was detected in transgenic F1 mice by Reverse Transcriptase- Polymerase Chain Reaction (RT-PCR). Resistin gene expression mouse has heavier body weight which was measured higher level of plasma glucose than that of normal mouse. And in diet-induced experiments, the abdominal fat pads were isolated from each 24h starvation and re-feeding after fasting group mice that were assessed by RT-PCR analysis. In fasting group mice, resistin expression was higher than that of re-feeding group mice. This result suggests that the resistin gene overexpressing mice may be became to obesity and be useful as an animal disease model to be diabetes mellitus caused by insulin resistance of resistin.

• 대한토목학회논문집
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• 제43권2호
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• pp.157-164
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• 2023

본 연구에서는 진동대 실험을 통하여 지진하중으로 인한 팔레트 랙의 손상 및 파괴 거동을 분석하고자 하였다. 팔레트 랙은 일반적인 적재설비의 한 종류로써 기둥, 보, 그리고 브레이스로 구성되어 지진하중에 저항한다. 팔레트 랙의 지진하중으로 인한 안전성을 분석하기 위하여, 실제 물류저장 시설에서 사용되고 있는 팔레트 랙을 대상으로 지진하중을 증가시켜가면서 하중으로 인한 팔레트 랙의 거동을 분석하기 위한 진동대 실험을 진행하였다. 진동대 실험 결과, 팔레트 랙은 비틀림이 발생하면서, 1층과 2층에 위치한 일부 부재의 연결부가 손상되고, 그로 인하여 적재설비가 파괴되는 것이 확인되었다.

• Biomolecules & Therapeutics
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• 제30권2호
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• pp.162-169
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• 2022

We utilized Fas21, a resveratrol analog, to modulate the function of hepatic stellate cells (HSCs) and liver sinusoidal endothelial cells (LSECs) during the angiogenic phase of murine liver metastasis by B16 melanoma and 51b colorectal carcinoma. Preangiogenic micrometastases were treated with Fas21 (1 mg/kg/day) or vehicle during the development of intra-angiogenic tracts. Mice treated with Fas21 showed reduced liver tumor foci in both liver metastasis models. Micrometastases were classified immunohistochemically, as well as according to their position coordinates and connection to local microvasculature. The volume of liver occupied by sinusoidal-type foci, containing infiltrating angiogenic capillaries, decreased by ~50% in Fas21-treated mice compared to vehicle-treated ones in both tumor metastasis models. The volume of portal foci, containing peripheral neoangiogenesis within a discontinuous layer of myofibroblasts, was similar in all experimental groups in both tumor metastasis models, but displayed enhanced necrotic central areas devoid of angiogenesis following Fas21 treatment. As a result, sinusoidal tumors from mice treated with Fas21 showed a 50% reduction in desmin(+)/asma(+) HSCs and CD31(+) vessel density, and a 45% reduction in intrametastatic VEGF mRNA compared with sinusoidal tumors from vehicle-treated mice. Necrotic portal metastases increased 2-4-fold in treated mice. In vitro, Fas21 reduced VEGF secretion by HSCs and 51b cells dose-dependently. Additionally, HSCs migration in response to tumor soluble factors was dose-dependently diminished by Fas21, as was LSEC migration in response to HSCs and tumor soluble factors. Resveratrol analog Fas21 inhibits the proangiogenic response of HSCs and LSECs during the development of murine liver metastasis.

• 대한토목학회논문집
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• 제28권2A호
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• pp.233-242
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• 2008

본 연구는 지진운동의 영향 하에서 강제 모멘트 골조로 이루어진 post-Northridge(덮개판) 연결부를 갖는 보의 탄성 및 비탄성 거동을 모델하기 위한 부등단면 보(IBS 보) 요소를 제시한다. 덮개판(IBS) 연결부를 갖는 부등단면 보의 탄성강성 매트릭스는 수치적분이 필요치 않은 수식으로 표현된다. 소성모델은 분포형이며 강체링크로 연결된 일련의 비선형 힌지로 구성 되어있고 경화법칙은 단조 및 임의 주기 하중에 대한 비탄성 거동과 국부좌굴의 효과를 고려할 수 있다. 또한 IBS 보 요소에 대한 항복면, 강성 변수, 그리고 경화(혹은 연화) 법칙 변수의 결정과정을 기술하였고 IBS 보 요소의 해석결과를 실험 및 FEM 해석결과와 비교하였다. IBS 보 요소의 해석결과는 실험 및 FEM 결과와 좋은 상관관계를 보였다.

• 대한소아치과학회지
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• 제51권1호
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• pp.11-21
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• 2024

This study aimed to analyze the prevalence and severity of infraoccluded primary molars (IPM) and their correlation with the agenesis of permanent successors (APS). A total of 4,011 panoramic radiographs from children aged 4 to 11 years who had all 8 primary molars were examined. The prevalence of APS was analyzed based on the severity and tooth type of IPM. The prevalence of IPM was 13.0%, and there was no difference between genders. The majority of the children had two IPMs each. In all tooth types, mild infraocclusion was the most prevalent, whereas severe infraocclusion was the least frequent. Among the types of primary molars, the lower primary first molar (62.3%) was the most affected, followed by the lower primary second molar (27.7%), the upper primary second molar (5.8%), and the upper primary first molar (4.2%). Infraocclusion was 11.2 times more prevalent in the mandible than in the maxilla, with no significant difference between the left and right sides. The correlation between IPM and APS was also investigated. Among the subjects, 177 had one or more agenesis of premolars, of whom 54 (30.5%) had IPM. Additionally, among the 521 individuals with IPM, 54 individuals exhibited APS (10.4%). This study identified a noteworthy prevalence of infraocclusion, with notable variations among molar types. The LPFM was particularly affected. The majority of cases were classified as mild in severity. Furthermore, a compelling association between IPM and APS was established. Understanding this connection may enhance treatment strategies for infraoccluded teeth and tooth agenesis.