• Journal of Gastric Cancer
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• v.21 no.3
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• pp.236-245
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• 2021

Purpose: The numeric N stage has replaced the topographic N stage in the current tumor node metastasis (TNM) staging in gastric carcinoma. However, the usefulness of the topographic N stage in the current TNM staging system is uncertain. We aimed to investigate the prognostic value of the topographic N stage in the current TNM staging system. Materials and Methods: We reviewed the data of 3350 patients with gastric cancer who underwent curative gastrectomy. The anatomic regions of the metastatic lymph nodes (MLNs) were classified into 2 groups: perigastric and extra-perigastric. The prognostic value of the anatomic region was analyzed using a multivariate prognostic model with adjustments for the TNM stage. Results: In patients with lymph node metastasis, extra-perigastric metastasis demonstrated significantly worse survival than perigastric metastasis alone (5-year survival rate, 39.6% vs. 73.1%, respectively, P<0.001). Extra-perigastric metastasis demonstrated significantly worse survival within the same pN stage; the multivariate analysis indicated that extra-perigastric metastasis was an independent poor prognostic factor (hazard ratio=1.33; 95% confidence interval=1.01-1.75). The anatomic region of the MLNs improved the goodness-of-fit (likelihood ratio statistics, 4.57; P=0.033) of the prognostic model using the TNM stage. Conclusions: The anatomic region of MLNs has an independent prognostic value in the numeric N stage in the current TNM staging of gastric carcinoma.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.4
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• pp.2094-2112
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• 2019

Focusing on the issue that the conventional Kernel Correlation Filter (KCF) algorithm has poor performance in handling scale change and obscured objects, this paper proposes an anti-occlusion and scale adaptive tracking algorithm in the basis of KCF. The average Peak-to Correlation Energy and the peak value of correlation filtering response are used as the confidence indexes to determine whether the target is obscured. In the case of non-occlusion, we modify the searching scheme of the KCF. Instead of searching for a target with a fixed sample size, we search for the target area with multiple scales and then resize it into the sample size to compare with the learnt model. The scale factor with the maximum filter response is the best target scaling and is updated as the optimal scale for the following tracking. Once occlusion is detected, the model updating and scale updating are stopped. Experiments have been conducted on the OTB benchmark video sequences for compassion with other state-of-the-art tracking methods. The results demonstrate the proposed method can effectively improve the tracking success rate and the accuracy in the cases of scale change and occlusion, and meanwhile ensure a real-time performance.

• Molecules and Cells
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• v.42 no.2
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• pp.161-165
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• 2019

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide and has high rates of metastasis. Transforming growth factor beta-inducible protein (TGFBI) is an extracellular matrix component involved in tumour growth and metastasis. However, the exact role of TGFBI in NSCLC remains controversial. Gene silencing via DNA methylation of the promoter region is common in lung tumorigenesis and could thus be used for the development of molecular biomarkers. We analysed the methylation status of the TGFBI promoter in 138 NSCLC specimens via methylation-specific PCR and evaluated the correlation between TGFBI methylation and patient survival. TGFBI promoter methylation was detected in 25 (18.1%) of the tumours and was demonstrated to be associated with gene silencing. We observed no statistical correlation between TGFBI methylation and clinicopathological characteristics. Univariate and multivariate analyses showed that TGFBI methylation is significantly associated with poor survival outcomes in adenocarcinoma cases (adjusted hazard ratio = 2.88, 95% confidence interval = 1.19-6.99, P = 0.019), but not in squamous cell cases. Our findings suggest that methylation in the TGFBI promoter may be associated with pathogenesis of NSCLC and can be used as a predictive marker for lung adenocarcinoma prognosis. Further large-scale studies are needed to confirm these findings.

• Annals of Surgical Treatment and Research
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• v.95 no.5
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• pp.258-266
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• 2018

Purpose: This study analyzes the impact of laparoscopic liver resection on intra-abdominal adhesion. Methods: Patients who underwent salvage liver transplantation after liver resection for hepatocellular carcinoma from January 2012 to October 2017 at our institution were included. Information about the severity of intra-abdominal adhesions was collected from a prospectively maintained database. Intra-abdominal adhesions were graded after the agreement of 2 surgeons who participated in the salvage liver transplantation based on predetermined criteria. Adhesion severity and demographic, operative, and postoperative data were compared between the laparoscopic group and the open group. Multivariate logistic regression was performed to consider potential factors related to severe adhesion during salvage transplantation. Results: Sixty-two patients who underwent salvage liver transplantation after liver resection were included in this study. Among them, 52 patients underwent open surgery, and 10 patients underwent laparoscopy. Adhesion was significantly more severe in the open group than in the laparoscopy group (P = 0.029). A multivariate logistic regression model including potential factors related to severe adhesion showed that laparoscopy (odds ratio, 0.168; 95% confidence interval, 0.029-0.970; P = 0.048) was the only significant factor. Conclusion: Laparoscopic liver resection for hepatocellular carcinoma can minimize intra-abdominal adhesion during salvage liver transplantation.

• Journal of the Korea Society of Computer and Information
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• v.23 no.12
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• pp.185-193
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• 2018

The purpose of this paper was to identify the relationship among the MBTI personality types, self-efficacy, major satisfaction and freshmen's academic achievements in airline service department. To this end, a survey was conducted in 113 university freshmen of airline service department from June 18 to 29, 2018. And the data were collected their MBTI results and GPA scores. MBTI results used to analyze student's personality type. The collected data were analyzed using 'SPSS Statistics 21.0'. Analysis methods such as frequency analysis, cross-tabulation analysis, factor analysis, reliability analysis, t-test, ANOVA, and multiple regression analysis were used. The findings of this study are as follows. The type of personality in the airline service department affects the self - efficacy such as self - control efficacy, confidence, preference of the task difficulty, and also affects the major satisfaction and the academic achievement. The self - efficacy affects the major satisfaction and the academic achievement, and also the major satisfaction can affect academic achievement. Therefore, by developing an effective teaching strategies that fits students' personality type characteristics, and by inducing motivation to learn, raising self-efficacy naturally will lead to higher major satisfaction and academic achievements.

• Clinical and Experimental Reproductive Medicine
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• v.46 no.3
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• pp.107-111
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• 2019

Objective: Spermatogenesis is a complex process that is regulated by a number of genes, some of which are involved in folate-dependent 1-carbon metabolism. Methionine synthase (encoded by MTR) is a key enzyme participating in this pathway. This study aimed to investigate the relationship of the MTR 2756A > G polymorphism with idiopathic male fertility in the Iranian population. Methods: The participants of this study included 100 men with idiopathic infertility and 100 healthy men as the control group. Genotyping of MTR 2756A > G was performed using the polymerase chain reaction and restriction fragment length polymorphism technique. The obtained data were analyzed using SPSS ver. 20.0 with a level of confidence of p< 0.05. Results: The frequencies of the A and G alleles at this locus were 77% and 23% in infertile patients and 84% and 16% in the control group, respectively. The frequencies of the GG, GA, and AA genotypes were 5%, 36%, and 59% in the infertile patients versus 3%, 27%, and 70% in the control group, respectively. No significant difference was observed in any genetic models. Conclusion: In general, the findings of this study suggest that the MTR 2756A > G single-nucleotide polymorphism is not a predisposing factor for idiopathic infertility in men.

• Journal of Yeungnam Medical Science
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• v.35 no.2
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• pp.187-191
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• 2018

Background: Respiratory distress syndrome (RDS) is a one of the most common cause of respiratory morbidity and mortality in neonates. This study was conducted to investigate the risk factors for RDS in full-term neonates. Methods: We conducted this retrospective study using medical records. The study group included 80 full-term neonates diagnosed with RDS and hospitalized in the neonatal intensive care unit between January 2012 and December 2016, at Yeungnam University Hospital. We analyzed sex, gestational age, birth weight, delivery method, maternal age, number of pregnancy, history of abortion, and complication of pregnancy. The control group included 116 full-time neonates who were hospitalized with jaundice during the same period. Results: The incidence of full-term RDS was more common in males (odds ratio [OR], 3.288; 95% confidence interval [CI], 1.446-7.479), cesarean section (OR, 15.03; 95% CI, 6.381-35.423), multiparity (OR, 4.216; 95% CI, 1.568-11.335). The other factors rendered no significant results. Conclusion: The risk factors for RDS in full-tern neonates were identified as male sex, cesarean section, and multiparity. Further studies involving more institutions are needed to clarify the risk factors for RDS in full-term infants.

• Journal of Preventive Veterinary Medicine
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• v.41 no.3
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• pp.129-132
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• 2017

The current study identified risk factors associated with porcine circovirus type 2 (PCV2) infection on pig farms in the Republic of Korea using a multinomial logistic regression model to evaluate the PCV2 infection status of pigs at different growth stages. Compulsory disinfection of visitors (odds ratio [OR]: 0.019, 95% confidence interval [CI]: <0.001-0.378, p=0.0095), compulsory registration of visitors (OR: 0.002, 95% CI: <0.001-0.184, p=0.0070), regular blood testing (OR: 0.012, 95% CI: <0.001-0.157, p=0.0007), and running on-farm biosecurity learning programs for workers (OR: 0.156, 95% CI: 0.040-0.604, p=0.0072 and OR: 0.201, 95% CI: 0.055-0.737, p=0.0155, respectively) were identified as factors which could reduce the risk of PCV2 infection. However, visitation by a regular veterinarian (OR: 32.733, 95% CI: 3.768-284.327, p=0.0016) was associated with PCV2 infection.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.24 no.6
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• pp.535-545
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• 2021

Purpose: This study aimed to analyze the practice of complementary feeding and its influencing factors in children under 2 years of age in Indonesia. Methods: This cross-sectional study used data obtained from the 2017 National Socioeconomic Survey. The sample totaled 1,751 households with children under 2 years of age, who received complementary feeding in urban and rural communities. Furthermore, the practice of complementary feeding was evaluated on the basis of the variations in provided food grouped into two categories: complete and incomplete. This study applied bivariate and multivariate analytical methods. Multivariate analysis was performed using binary logistic regression. Results: The proportion of children under 2 years of age who received complementary feeding with complete variant food was 15.9%, while that with incomplete variant food was 84.1%. Furthermore, the factor influencing the practice of complementary feeding among the children was the mother's educational level (odds ratio: 1.481, 95% confidence interval: 0.245-0.943). Conclusion: Complete complementary feeding, which involves a variety of food sources, is the best approach to improve the nutritional status of infants. Therefore, the source of food for complementary feeding must be accessible to all communities.

• Journal of Distribution Science
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• v.19 no.10
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• pp.87-97
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• 2021

Purpose: Compared with the past when Japanese retailers used to hesitate to open their shops in the Korean market, because of anti-Japan sentiment, they show confidence in Korea in recent. This study, thus, aims at examining how socio-demographic factors have an impact on customer attitudes towards a Japanese retailer as a shopping destination. Research design, data, and methodology: After the literature review process, the authors have developed a variety of questions to verify the relationship amongst the variables like nationalism, consumer ethnocentrism, war animosity, store country-of-origin and anti-Japan sentiment. Furthermore, after collected questionnaires, the authors used confirmative factor analysis (CFA), T test and linear regression analysis to verify the 25 hypotheses developed. Results: Except for a household size element, it is found that gender, age, education and income levels are related to the degree of nationalism, ethnocentrism, war animosity, store country-of-origin and anti-Japan sentiment. In other words, socio-economic elements influenced Korean customer attitudes towards Japanese retailers. Conclusions: Korean customers tend to show different shopping attitudes towards the Japanese retailers, depending on the characteristics of socio-demographic elements. Furthermore, changing socio-demographic factors will provide positive business opportunities for Japanese retailers in the future.