• 한국의학물리학회지:의학물리
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• 제33권4호
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• pp.80-87
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• 2022

Purpose: Proton therapy has different relative biological effectiveness (RBE) compared with X-ray treatment, which is the standard in radiation therapy, and the fixed RBE value of 1.1 is widely used. However, RBE depends on a charged particle's linear energy transfer (LET); therefore, measuring LET is important. We have developed a LET measurement method using the inefficiency characteristic of an EBT3 film on a proton beam's Bragg peak (BP) region. Methods: A Gafchromic EBT3 film was used to measure the proton beam LET. It measured the dose at a 10-cm pristine BP proton beam in water to determine the quenching factor of the EBT3 film as a reference beam condition. Monte Carlo (MC) calculations of dose-averaged LET (LET_d) were used to determine the quenching factor and validation. The dose-averaged LETs at the 12-, 16-, and 20-cm pristine BP proton beam in water were calculated with the quenching factor. Results: Using the passive scattering proton beam nozzle of the National Cancer Center in Korea, the LET_d was measured for each beam range. The quenching factor was determined to be 26.15 with 0.3% uncertainty under the reference beam condition. The dose-averaged LETs were measured for each test beam condition. Conclusions: We developed a method for measuring the proton beam LET using an EBT3 film. This study showed that the magnitude of the quenching effect can be estimated using only one beam range, and the quenching factor determined under the reference condition can be applied to any therapeutic proton beam range.

• Journal of Animal Science and Technology
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• 제65권5호
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• pp.939-950
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• 2023

This study was conducted to assess the impact of growing condition variables on alfalfa (Medicago sativa L.) productivity. A total of 197 alfalfa yield results were acquired from the alfalfa field trials conducted by the South Korean National Agricultural Cooperative Federation or Rural Development Administration between 1983 and 2008. The corresponding climate and soil data were collected from the database of the Korean Meteorological Administration. Twenty-three growing condition variables were developed as explaining variables for alfalfa forage biomass production. Among them, twelve variables were chosen based on the significance of the partial-correlation coefficients or potential agricultural values. The selected partial correlation coefficients between the variables and alfalfa forage biomass ranged from -0.021 to 0.696. The influence of the selected twelve variables on yearly alfalfa production was summarized into three dominant factors through factor analysis. Along with the accumulated temperature variables, the loading scores of the daily mean temperature higher than 25℃ were over 0.88 in factor 1. The sunshine duration at temperature between 0℃-25℃ was 0.939 in factor 2. Precipitation days were 0.82, which was the greatest in factor 3. Stepwise regression applied with the three dominant factors resulted in the coefficients of factors 1, 2, and 3 for 0.633, 0.485, and 0.115, respectively, and the R-square of the model was 0.602. The environmental conditions limiting alfalfa growth, such as daily temperature higher than 25℃ or daily mean temperature affected annual alfalfa production most substantially among the growing condition variables. Therefore, future cultivar selection should consider the capability of alfalfa to be tolerant to extreme summer weather along with biomass production potential.

• KSBB Journal
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• 제19권4호
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• pp.263-268
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• 2004

최근 생체 내에서 다른 약리활성을 보이는 키랄물질의 고순도 제조에 관심이 증가되고 있다. 현재 널리 사용되고 있는 것은 키랄고정상을 이용한 기존 분리방법에 비해서, 제조 후 안정성과 환경적인 측면을 고려한 초임계유체를 이용한 분리방을 시도하였다. 본 연구에서는 키랄물질인 ibuprofen의 최적의 분리 조건을 구하기 위해서 온도와 압력, 첨가되는 IPA의 양에 따른 체류인자와 분리도의 영향을 고찰하였다. 온도가 감소하고 압력이 증가할수록 체류인자는 감소하였다. IPA의 양에 따라 더 큰 영향을 받아서 IPA의 양이 많을수록 분리도는 감소하는 경향을 보였다. 실험으로부터 정한 최적의 분리조건은 130 bar, 311.15 K, 4% IPA (vol.)일 때이었다. 동일한 주입량에서 액체 크로마토그래피에서는 비선형의 용출곡선을 보였지만, 초임계유체 크로마토그래피에서는 선형의 용출곡선을 얻었다.

• 한국물환경학회지
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• 제28권2호
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• pp.213-218
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• 2012

Abnormal dissolved oxygen concentration in aquatic habitat, both depletion and supersaturation, can be stress factor to aquatic animals. In this study the nationwide distribution of oxygen supersaturation was analyzed for three categories of streams (43 urban streams, 15 rural streams, and 14 forest streams) by using monitoring network data of the Korean Ministry of Environment. From the distribution analysis 30% of urban streams showed hyperoxic condition of eutrophic level, while no forest stream showed hyperoxic condition. The physiological effect of hyperoxia on fish was examined using two species of fish Zacco koreanus, which resulted in higher concentration of a stress hormone (cortisol) in fish exposed to hyperoxic concentration (196%) of oxygen. This study shows that hyperoxic condition is ubiquitous in urban and rural Korean streams, and it can be a stress factor to aquatic animals.

• KSTLE International Journal
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• 제1권1호
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• pp.8-11
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• 2000

A surface crack in a semi-infinite body under Hertzian contact was considered. The simplified method used to estimate stress intensity factor K for specimen was extended to the model which is chosen in this paper. Very satisfactory results are obtained comparing with those known and it is proved that the method is more convenient than other methods. The results of the analysis show that due to the presence of $K_I$ for unlubricated condition, mode I fracture is active in the field below the surface and the maximum $K_{I}$ is obtained when the trailing edge of Hertzian contact reaches a position over the crack. The magnitudes of stress intensity factors $K_I$ and $K_Il$ increase with increasing friction forces. For a surface crack perpendicular to the contact surface, the stress intensity factor $K_I$ reaches its maximum value at a depth very close to the surface. Driving forve fer crack initiation and propagation is $K_I$ for unlubricated condition and $K_Il$ for both fluid and boundary lubricated condition.n.

• 한국자동차공학회논문집
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• 제20권1호
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• pp.141-146
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• 2012

Aluminum alloys have been used with various thicknesses suitable for light weight of structure. It is known that the thickness effect of material is an important factor affecting fatigue crack propagation under constant fatigue stress condition. In this work, we presented the behavior of fatigue crack propagation in thin plate compared to thick plate Al 2024-T3 alloy with referred thickness effect in a correlative equation determined by the shape factor and the loading factor. We chose two factors that are used in the correlative equation with considering that the experiments were carried out under a constant fatigue stress condition. The thickness ratio of thin plate compared to thick plate and the equivalent effective stress intensity factor ratio depending on thickness were chosen as shape and loading factors. A correlative equation is utilized to determine the equivalent effective stress intensity factor range of thin plate and identify the degree of increasing phenomenon of fatigue life in thin plate compared to thick plate.

• Nuclear Engineering and Technology
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• 제53권3호
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• pp.732-740
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• 2021

Scattering resonance of medium mass nuclides leads complex spectrum in the fast reactor, which requires thousands of energy groups in the spectrum calculation. When the broad-group cross sections are collapsed, reaction rate cannot be completely conserved. To eliminate the error from energy collapsing, the Super-homogenization method in energy collapsing (ESPH) was employed in the fast reactor code SARAX. An ESPH factor was derived based on the ESPH-corrected SN transport equation. By applying the factor in problems with reflective boundary condition, both the effective multiplication factor and reaction rate were conserved. The fixed-source iteration was used to ensure the stability of ESPH iteration. However, in the energy collapsing process of SARAX, the vacuum boundary condition was adopted, which was necessary for fast reactors with strong heterogeneity. To further reduce the error caused by leakage, an additional conservation factor was proposed to correct the neutron current in energy collapsing. To evaluate the performance of ESPH with conservation factor, numerical benchmarks of fast reactors were calculated. The results of broad-group calculation agreed well with the direct full-core Monte-Carlo calculation, including the effective multiplication factor, radial power distribution, total control rod worth and sodium void worth.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 1999년도 봄 학술발표회 논문집
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• pp.277-284
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• 1999

This study describes the influence factors related to slope failure pattern and dimension in the southern Kyounggi area. Intrusive and metamorphic rocks are distributed in the study area. Geological condition, rainfall property and slope geometry are influence on slope failure characteristics in the study we& Geological factors related to slope failure are rock type, geological structure and weathering condition. Because of deep soil (RS-CW) depth of granite region, circular failure type is major failure pattern in granite region. Almost granite slopes with circular or surface failure pattern are failed during heavy rainfall season. But typical wedge failure type related to geological structure factor is a main failure pattern of metamorphic rock slope. Additionally failure dimension is influenced by geological factors and several factors, i.e. natural slope condition, failure type, rainfall intensity and etc. failure height/width ratio and thickness/length ratio of granite slope are 0.88 and 0.23. But the ratios of metamorphic rock slope are 1.36 and 0.19.

• 소성∙가공
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• 제11권2호
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• pp.132-137
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• 2002

Using the Taguchi method, optimum process condition of lead frame blanking has been determined in the point of view of shape of blanked profile. As the main process parameters, clearance, strip holding pressure and bridge width are selected. According to the orthogonal array table, three levels of experiment have been carried out for each factor. The optimal blanking condition is analyzed with the SN ratio. It has been verified that the optimal Process condition can be determined with a combination of basic blanking experiment and experiment design method. Both the effect of each factor and gain can be judged in the quantitative manner from the analysis of SN ratio.

• 한국정밀공학회지
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• 제17권2호
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• pp.137-143
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• 2000

An automobile clutch diaphragm spring is operating in a closed clutch housing under high temperature and subject to high stress concentration in driving condition, which frequently causes cracks and fracture. The material of spring is required to possess sufficient fatigue strength and tenacity, which depend largely on the condition of tempering heat treatment. In this paper, specimens are made under a number of different tempering temperatures md tested to find the optimal tempering heat treatment condition. The experiments include the verification of microscopic structure, hardness, tensile strength, fatigue crack growth rate, stress intensity factor range and residual stress. Also, decarbonization, which occurs in actual heat treatment process, is measured and allowable decarbonization depth is studied by durability test.