• Title/Summary/Keyword: concentration effects

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The Effects of Air Conditioner Noise on Classroom Acoustics (교실 음향에 대한 에어컨 소음의 영향)

  • Kim, Su-Yeon;Jeon, Jin-Yong
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.05a
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    • pp.176-179
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    • 2005
  • A case-study in classroom acoustics was conducted and the effects of two types(system air conditioner and packaged air conditioner) of air conditioner were investigated. Acoustical measurements were made in two different classrooms. Each classroom has different acoustics showing sound quality of air conditioner. Mental concentration test was conducted to evaluate the effects of air conditioner noise with different sound presure level(dBA). Speech intelligibility test was also planed with adopting Korean phonetic balanced words.

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The Effects of Salt Treatment on Thermal Coagulation of Diluted Eggs in Cookery (난액의 열응고조리에 미치는 식염의 영향)

  • 박영선
    • Journal of the Korean Home Economics Association
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    • v.17 no.4
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    • pp.35-42
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    • 1979
  • The effects of salt concentration on the qualities of cooked egg preparations were evaluated. Diluted egg samples which contained different amounts of slat were prepared by diluting whole egg fluid with rice washing, anchovy stock , or distilled water. After heating them rapidly, hardness, gel strength, and amount of syneresis were determined along with the performance of sensory test. the pH of the diluted eggs also measured before heating. Results obtained from these experiments are summarized in the following. 1. The pH of whole egg, egg yolk, and egg white was 7.32, 6.31, and 8.41 , respectively. 2. The pH whole eggs after addition of diluting solutions and salt showed a little differences over the whole salt concentration as follows. distilled water dilution > anchovy stock dilution > rice washing dilution 3. The hardness and gel strength of cooked samples were increased with the increase of salt concentration in the range of low salt concentrations of all diluting solution. These physical properties marked maximal values at salt concentration of 3% and then decreased as salt concentration increased. 4. Amount of syneresis decreased as salt concentration increased regardless of all diluting solutions used. 5. In sensory test, 1% salt concentration were scored good by the panel members regardless of diluting solutions which showed no significant difference among three diluting solutions.

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The Effects of the Surfactant Type on the Nanofluids Stability (계면활성제 특성에 따른 나노입자 분산안정도 향상 연구)

  • Kang, Chi-Hoon;Hong, Sung-Wook;Kang, Yong-Tae;Koo, June-Mo
    • Proceedings of the SAREK Conference
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    • 2008.11a
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    • pp.275-280
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    • 2008
  • The effects of the surfactant type, i.e., CTAB(cationic), SDS(anionic), and GA(polymeric), on the stability of 0.1 vol.% $Al_2O_3$ nanofluids were investigated. The changes in size and zeta potential of nanoparticles in nanofluids with pH, surfactant concentration, and time were experimentally observed. The nanofluids adding CTAB, which ionizes of the same charge with the bare particle surface, was found to have the best stability regardless of the surfactant concentration, whereas those with SDS became unstable under low surfactant concentration conditions, i.e. lower than the critical micellel concentration(CMC), before the charge reversal occurred. With higher SDS concentration over CMC, they became stable. Gum Arabic, which had been used often to stabilize the nanofluids, was also tested. In result, it was found that the type and concentration of surfactants to add should be selected considering pH and the sign of the bare particle surface charge.

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High concentration of calcium represses osteoblast differentiation in C2C12 cells

  • Lee, Ye Jin;Han, Younho
    • International Journal of Oral Biology
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    • v.45 no.4
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    • pp.162-168
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    • 2020
  • Calcium is the most abundant stored mineral in the human body and is especially vital for bone health; thus, calcium deficiency can cause bone-related diseases, such as osteopenia and osteoporosis. However, a high concentration of serum calcium, which is commonly known as hypercalcemia, can also lead to weakened bones and, in severe cases, osteosarcoma. Therefore, it is necessary to maintain the concentration of calcium that is appropriate for bone biology. In the present study, we aimed to elucidate the effects of high concentration of calcium, approximately 2 folds the normal calcium level, on osteoblast differentiation. The CaCl2 treatment showed dose-dependent suppression of the alkaline phosphatase activity and mineralized nodule formation. Calcium showed cytotoxicity at an extremely high concentration, but a moderately high concentration of calcium that results in inhibitory effects to osteoblast differentiation showed no signs of cytotoxicity. We also confirmed that the CaCl2 treatment repressed the mRNA expression and protein abundance of various osteogenic genes and transcriptional factors. Considered together, these results indicate that a high concentration of calcium negatively regulates the osteoblast differentiation of C2C12 cells.

Development of a portable system for monitoring indoor particulate matter concentration (휴대용 실내 미세먼지 농도 측정 장치 개발)

  • Kim, Yoo Jin;Choi, Hyun Seul;Go, Taesik
    • Journal of the Korean Society of Visualization
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    • v.20 no.1
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    • pp.45-51
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    • 2022
  • Airborne particulate matter(PM) has been a global environmental problem. PM whose diameter is smaller than 10 ㎛ can permeate respiratory organs and has harmful effects on human health. Therefore, PM monitoring systems are necessary for management of PM and prevention of PM-induced negative effects. Conventional PM monitoring techniques are expensive and cumbersome to handle. In the present study, two types of PM monitoring devices were designed for measuring indoor PM concentration, portably. We experimentally investigated the performance of three commercial PM concentration measurement sensors in a closed test chamber. As a result, PM2008 sensor showed the best PM concentration measurement accuracy. Linear regression method was applied to convert PM concentration value acquired from PM2008 sensor into ground truth value. A mobile application(app.) was also created for users to check the PM concentration, easily. The mobile app. also provides safety alarm when the PM10 concentration exceeds 81 ㎛/m3. The developed hand-held system enables the facile monitoring of surrounding air quality.

Studies on the Antioxidant Effects of Mori Folium Extract (상엽(桑葉)추출물의 항산화효과에 대한 연구)

  • Lee, Ji-Eun;Lim, Hyung-Ho;Song, Yun-Kyung
    • The Journal of Korean Medicine
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    • v.28 no.1 s.69
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    • pp.148-158
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    • 2007
  • Objective : The objective of this study was to investigate the antioxidant effects of Mori Folium extract. Methods Total antioxidant status was examined by total antioxidant capacity(TAC) and total antioxidant response(TAR) against potent free radical reactions. The effect of Mori Folium extract was examined by measuring total phenolic content, concentration at which 1,1-dipheny1-2-picrylhydrazyl(DPPH) radical scavenging activity was inhibited, inhibitory effect on lipid peroxidation, and the effect on reactive oxygen species(ROS) generation. Results : 1. TAC and TAR of Mori Folium extract at the concentration of 5 mg/ml were 1.61 and 1.24 mM Trolox equivalents, respectively. 2. Total phenolic content of Mori Folium extract at the concentration of 5 mg/Ml was 1.70 mM gallic acid equivalent. 3. Concentration of Mori Folium extract at which DPPH radical scavenging activity was inhibited by 50% was 2.29 m9/m4 as compared to 100% by Pyrogallol solution as a reference. 4. The inhibitory effect of the extract on lipid peroxidation was examined using rat liver mitochondria induced by FeSO$_4$/ascorbic acid. Mori Folium extract at the concentration of 10 mg/ml significantly decreased thiobarbituric acid reactive substances(TBARS) concentration. The extract prevented lipid peroxidation in a dose-dependent 5. The effect of Mori Folium extract on reactive oxygen species(ROS) generation was examined using a celt-free system induced by hydrogen peroxide FeSO$_4$. Addition of 1 mg/ml of Mori Folium extract significantly reduced dichlorofluorescein(DCf) fluorescence. The extract caused concentration-dependent attenuation of the increase in DCF fluorescence, indicating that the extract significantly prevented ROS generation in vitro. Conclusion ; The antioxidant effects of Mori Folium extract seem to be due, at least in part, to the prevention offree radical-induced oxidation, fllowed by inhibition of lipid peroxidation.

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Effects of Gardeniae Fructus on Cytokines in Mouse Macrophage (치자(梔子)가 대식세포의 Cytokine에 미치는 영향)

  • Cha, Ji-Hea;Lim, Eun-Mee
    • The Journal of Korean Obstetrics and Gynecology
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    • v.27 no.1
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    • pp.1-16
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    • 2014
  • Objectives: The purpose of this study was to investigate the effects of Gardeniae Fructus Water Extract (GF) on the production of inflammatory mediators in RAW 264.7 cell treated with lipopolysaccharide (LPS). Methods: Gradeniae Fructus was extracted with distilled water (2,000 ml) for 2 hours. In order to evaluate cytotoxicity of GF, 3 - (4,5-dimethylthiazol-2-yl) - 2,5 - diphenyltetrazolium bromide (MTT) assay was performed. To investigate antiinflammatory effects, the concentration of nitric oxide (NO) was measured with No assay, calcium (Ca) was measured with Fluo-4 Ca assay, and cytokine was measured by Bio-Plex cytokine assay in RAW 264.7 cell. And when p-value is below 0.05, it is judged to have the significant difference statistically. Results: 1. GF did not show any cytotoxicity. 2. GF suppressed the production of NO and Ca at the concentration of 25, 50, 100 and $200{\mu}g/ml$. 3. GF suppressed the production of interleukin (IL)-$1{\beta}$, IL-10, IL-12p40, macrophage-colony stimulating factor (M-CSF), macrophage inflammatory protein (MIP)-$1{\beta}$ and keratinocyte chemoattractant(KC) at the concentration of 25, 50, 100 and $200{\mu}g/ml$. 4. GF suppressed the production of vascular endothelial growth factor (VEGF), granulocyte-colony stimulating factor (G-CSF) and monocyte cheomattractant protein (MCP)-1 at the concentration of 25, 50 and $100{\mu}g/ml$. 5. GF suppressed the production of granulocyte macrophage-colony stimulating factor (GM-CSF) and regulated on activation, normal T cell expressed and secreted (RANTES) at the concentration of 25 and $50{\mu}g/ml$. 6. GF suppressed the production of MIP-2 at the concentration of 50 and $100{\mu}g/ml$, and tumor necrosis factor (TNF)-${\alpha}$ at the concentration of 50 and $200{\mu}g/ml$. Conclusions: These results suggest that GF has anti-inflammatory effect and immuno-modulating activity.

Anti-inflammatory effects of Parthenocissus tricuspidata extracts (담쟁이덩굴 추출물의 항염증 활성 연구)

  • Shin, Kyung-Soon;Yoo, Ji-Hyun;Kil, Ki-Jung
    • The Korea Journal of Herbology
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    • v.34 no.1
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    • pp.91-98
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    • 2019
  • Objectives : While inducing inflammatory response due to LPS it will investigate mechanism associated with anti-inflammatory effects from macrophages and provide basic data for the possible use as anti-inflammatory materials. Methods : We investigated cell viability, NO, $TNF-{\alpha}$ and IL-6 by ELISA and expressions of iNOS, COX-2, MAPKs and $NF-{\kappa}B$ were measured in RAW 264.7 cells induced by LPS. Results : The cell viability of Parthenocissus tricuspidata extracts(PTE) identified in macrophages showed that cell viability rate was more than 99% at the concentration of 8, 40, and $200{\mu}g/mL$. NO generated amounts revealed that it relied on concentration and was significantly reduced compared to the control. The expression of iNOS was restrained by the control at the concentration of 200 and $400{\mu}g/mL$. In addition, the expression of COX-2 was found to be significantly reduced to the untreated control at the concentration of $400{\mu}g/mL$. $TNF-{\alpha}$ relied on concentration and showed a significant decreased compared to the control. In contrast, IL-6 relied on concentration, reduced compared to the control. Phosphorylation of ERK, JNK, and p38 mediated by LPS were restrained by relying on concentration. Phosphorylation and decomposition of $I{\kappa}B{\alpha}$ as well as p65 nuclear transmission of $NF-{\kappa}B$ subunit were restrained. Conclusions : By restraining the activation of $NF-{\kappa}B$, anti-inflammatory effects were revealed by reducing phosphorylative activation of MAPKs, restraining the expression of iNOS and COX-2 and restraining the creation of NO, IL-6, and $TNF-{\alpha}$. Therefore, it can be assumed that they can be used as a variety of anti-inflammatory materials.

The Effect of Clothing Coloration and Ope of Pants/Skirt on Impression Formation (상.하의 배색과 하의형태가 인상형성에 미치는 영향)

  • 문주영;강경자
    • Journal of the Korean Society of Clothing and Textiles
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    • v.27 no.1
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    • pp.111-122
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    • 2003
  • The purpose of this study is to investigate the effect of clothing coloring and type of pants/skirt as clothing cues on impression of college female students. The experimental materials developed for this study are a set of stimuli and response scales. Thirty two color pictures of various combinations of colors for shirt, and colors and type of pants/skirt were manipulated on computer drawing. For visual evaluation of women's casual wears about colors and type, 7-point scales were designed. The subjects consist of 192 female and male undergraduate students in Chinju city. The results of this study can be summaried as follow: As analyzing the impression of female figure by the color of shirt and the color and type of pants/skirt, five factors including appearance valuation, concentration of attention, clearness, stability, and activity were found to be important. Color of shirt have significant effects on appearance valuation, concentration of attention, clearness, stability, and activity. Color of pants and shirt also have significant effects on all five factors. Especially, they strongest predictors for stability and activity. Type of pants/skirt significantly effects on concentration of attention and activity. In the effects of interactions between each variable, the combination of pants colors and type of pants/skirt had significant effects on appearance valuation, stability factors. Also shirt and pants colors had an significant effects on appearance valuation, stability, and activity. But in the impression formation of concentration of attention and clearness, only the combination of shirt colors and pants forms was more significant.

Effects of Biozyme on the Ethanol Metabolism in vivo and in vitro (바이오짐의 에탄올 대사에 대한 영향)

  • 남석우;박승희;윤성필;서동완;남태균;홍성렬;이향우
    • Biomolecules & Therapeutics
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    • v.3 no.2
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    • pp.171-175
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    • 1995
  • Effects of $Biozyme_{R}$ and $\textrm{Business}_{R}$ on alcohol metabolism in rats, and on the activities of alcohol dehydrogenase(ADH) and acetaldehyde dehydrogenase(ALDH) were studied in vitro. Alcohol concentration in rat blood was decreased after the treatment of Business(3.3 mι/kg, Biozyme 1.67 mg/wι) and Biozyme(3.3 mι/kg, 1.67 mg/mι) prior to the administration of ethanol(25%, 0.83 g/kg). And the acetaldehyde concentration of rat blood was also decreased when compared with control values in the same condition. Effects of Biozyme on ADH and ALDH activity were also studied. While the ALDH activity was elevated in the presence of Biozyme(2 $\mu\textrm{g}$/assay), the ADH activity was not influenced by Biozyme at the concentration range from 2 $\mu\textrm{g}$/assay to 0.2 mg/assay. In summary, Biozyme accelerated the rate of ethanol metabolism and the acceleration might be due to the increase in ALDH activity.vity.

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