• Proceedings of the KSME Conference
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• 2000.04a
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• pp.304-308
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• 2000

In this work, an equation of J-integral for a penny-shaped crack at the end of the cord embedded in rubber matrix is proposed. The dimensional analysis is applied to derived to the equation of J-integral. We assume that the energy Parameter J is separated into the deformation and the geometry function, and which is proved using by separation parameter.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.33B no.7
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• pp.40-50
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• 1996

An unified compliant control algorithm to regulate the force by dual arms is proposed, where tow arms are treated as one arm in a kinematic viewpoint. The force error calculated form the information of two force/torque sensors attached to the end of each arm is transferred to minimum actuator coordinates, and then is distributed to total system actuator coordinates. The position adjustment at the total actuator coordinates is computed based on the effective computed based on the effective compliance matrix with respect to total actuator coordinates, which is obtained by coordinate transformation between the task coordinates and the total actuator coordinates. An experiment is carried out for dual arms with asymmetric kinematic structure to control an interaction force between manipulators and the environment. The performances of the proposed control algorithm are experimentally compared to those of dual arms employing master/slave scheme. The proposed compliant control algorithm not only ouperforms other algorithms, but also can be treated as an unified approach n the sense that it can be applied to arbitrary dual arm systems with general kinematic structures.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.23 no.6
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• pp.683-691
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• 2010

In this paper, using an adjoint variable method, we develop a design sensitivity analysis(DSA) method applicable to heat conduction problems in steady state. Also, a topology design optimization method is developed using the developed DSA method. Design sensitivity expressions with respect to the thermal conductivity are derived. Since the already factorized system matrix is utilized to obtain the adjoint solution, the cost for the sensitivity computation is trivial. For the topology design optimization, the design variables are parameterized into normalized bulk material densities. The objective function and constraint are the thermal compliance of structures and allowable material volume respectively. Through several numerical examples, the developed DSA method is verified to yield very accurate sensitivity results compared with finite difference ones, requiring less than 0.25% of CPU time for the finite differencing. Also, the topology optimization yields physical meaningful results.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.11 no.2
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• pp.126-134
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• 2001

Statistical approaches for analysis of data from the limited number of samples in ship building industry(SBI) collected by an industrial hygienist for checking compliance to an occupational standard were considered. Sampling for compliance usually has been guided by judgment selection, rather than true randomness, resulting in the creation of compliance samples which approximate a censored sample from the upper tail of the exposure distribution. Similar exposure groups(SEGs) including welding and painting process were established to assess representative values in each groups after reviewing the whole production line in SBI. For the convenient statistical approaches, the code has assigned to each SEGs. The descriptive statistics and probability plotting were used to yield the representative values in each SEGs. In the first step, SEGs of 558 were established from 5 ship building companies. The 38 SEGs showed the uncertainty are divided into each 5 companies and assessed the representative values again. The 44 SEGs in each companies was not showed the normal and lognormal distribution was analyzed each data. And also, recommendation was suggested to resolve the uncertainty in each groups.

• Journal of the Korean Applied Science and Technology
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• v.29 no.4
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• pp.552-560
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• 2012

Drug delivery technologies are patent protected formulation technologies that modify drug release profile, absorption, distribution, and elimination for the benefit of improving product efficacy and safety, as well as patient convenience and compliance. The most commonly used transdermal system is the skin patch using various types of technologies. Compared with other method of dosage, it is possible to use for a long term. It is also possible to stop the drug dosage are stop if the drug dosage lead to side effect. Polysaccharide, such as karaya gum and locust bean gum(LBG)/water-soluble chitosan oligomer(WSCO) were selected as base materials of TDS. Also, these polymers were characterized in terms of enhancers, tacrine contents. Among these polysaccharide, the permeation rate of karaya gum matrix was fastest in tacrine such as lipophilic drug in vitro. We used glycerin, PEG 400, and PEG 800 as enhancers. Therefore, transdermal absorption of tacrine could be improved by changing vehicle composition or by using penetration enhancers. Especially it would be anticipated that the high permeation efficacy could be obtained by using vehicle that has enhancing effect for itself and by adding enhancers to it.

• Journal of Institute of Control, Robotics and Systems
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• v.6 no.2
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• pp.190-196
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• 2000

A hybrid position/force control scheme to regulate the force and position by dual arms is proposed where two arms are treated as one rm in a kinematic viewpoint. The force error calculated from the information of two force/torque sensors attached to the end of each arm is transferred to minimum configuration space coordinates and then is distributed to total system joint coordinates, The position adjustment at the total con-figuration coordinates is computed based on the effective compliance matrix with respect to total joint coordinates which is obtained by coordinate transformation between the task coordinates and the total joint coordinates. The proposed scheme is applied to sawing task. When the trajectory of the saw is planned to follow a line in a horizontal plane 2 position parameters are to be controlled(i.e., two translational positions) Also a certain level of contact force has to be controlled along the vertical direction(i.e. minus z-direction) not to loose the contact with the object to be sawn. We experimentally show that the performance of the velocity and force response are satisfactory. The proposed hybrid control scheme can be applied to arbitrary two cooperating arm system regardless of their kinematic structure and the number of actuated joints.

• Architectural research
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• v.11 no.2
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• pp.27-34
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• 2009

The purpose of this study is to investigate the problem of crack repair materials and methods in existing concrete structure and to propose the effective injection method on crack repair by packer type. The result of this study is as follows. It is investigated that the crack width in the inner matrix of concrete structure is decreased about 30-40% than that in the surface of the concrete structure. Also it is showed that the possibility which could be monolithic with injection part became higher if the injection part is installed near to surface of concrete on the punching method to vertical direction against crack area. The injection of repair material can be poured smoothly under about $10N/mm^2$ pressure on the condition that cracks are monolithic with injection part without dust by drill. The method which is effective injection for a repair material is the punching method in compliance with coredrill. But, the research continuously is necessary about minimum injection pressure.

• Analytical Science and Technology
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• v.33 no.6
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• pp.262-273
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• 2020

A fluorine content analysis method for krill oils, which is a representative oil formulation in foods, was developed in compliance with the Korea Food and Drug Ministry's "Guidelines for Validation of Testing Methods Related to Food". Using this method for krill oils, the presence of impurities was evaluated via combustion-ion chromatography (C-IC). A review of published technical data on fluorine in krill oils showed that while the traditional wet potentiometric method was typically used, it was not reliable. Moreover, there was no food testing/analysis laboratory in Korea to perform a fluorine test analysis on such an oil matrix. Therefore, we identified halogen (fluorine) tests, developed to national and international standards, and developed a test method suitable for krill oils by selecting a C-IC method that is sufficiently applicable to the oil matrix. Based on the characteristics of the oil matrix, the optimal test method was established through various experiments by reviewing the concerns related to loss and interference in the preparation and introduction of samples. The fluorine content test was carried out on 11 krill oil products that were purchased online. Most products (with the exception of only one) were found to contain less than the reporting limit obtained by the test method. Furthermore, after additional testing, a high fluorine content of approximately 2,000 ~ 3,000 mg/kg was detected on the krill surface, although the concentration varied depending on the area of the krill. A comparison with samples from two ISO/IEC 17025 testing laboratories confirmed that there was no significant difference in the statistical analysis results obtained by ANOVA among the three laboratories. A testing guide for fluorine content analysis was completed.

• Journal of Life Science
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• v.32 no.2
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• pp.175-188
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• 2022

Relaxin has been demonstrated to have regulatory functions on both the smooth muscle and extracellular matrix (ECM) of blood vessels and fibrotic organs. The diverse mechanisms by which relaxin acts on small resistance arteries and fibrotic organs, including the bladder, are reviewed here. Relaxin induces vasodilation by inhibiting the contractility of vascular smooth muscles and by increasing the passive compliance of vessel walls through the reduction of ECM components, such as collagen. The primary cellular mechanism whereby relaxin induces arterial vasodilation is mediated by the endothelium-dependent production of nitric oxide (NO) through the activation of RXFP1/PI3K, Akt phosphorylation, and eNOS. In addition, relaxin triggers different alternative pathways to enhance the vasodilation of renal and mesenteric arteries. In small renal arteries, relaxin stimulates the activation of the endothelial MMPs and EtB receptors and the production of VEGF and PlGF to inhibit myogenic contractility and collagen deposition, thereby bringing about vasodilation. Conversely, in small mesenteric arteries, relaxin augments bradykinin (BK)-evoked relaxation in a time-dependent manner. Whereas the rapid enhancement of the BK-mediated relaxation is dependent on IK_Ca channels and subsequent EDH induction, the sustained relaxation due to BK depends on COX activation and PGI₂. The anti-fibrotic effects of relaxin are mediated by inhibiting the invasion of inflammatory immune cells, the endothelial-to-mesenchymal transition (EndMT), and the differentiation and activation of myofibroblasts. Relaxin also activates the NOS/NO/cGMP/PKG-1 pathways in myofibroblasts to suppress the TGF-β1-induced activation of ERK1/2 and Smad2/3 signaling and deposition of ECM collagen.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.28 no.5
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• pp.441-449
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• 2015

In this paper we perform a linearized buckling analysis using the Kirchhoff plate theory and the von Karman nonlinear strain-displacement relation. Design sensitivity analysis(DSA) expressions for plane elasticity and buckling problems are derived with respect to Young's modulus and thickness. Using the design sensitivity, we can formulate the topology optimization method for minimizing the compliance and maximizing eigenvalues. We develop a topology optimization method applicable to plate buckling problems using the prestress for buckling analysis. Since the prestress is needed to assemble the stress matrix for buckling problem using the von Karman nonlinear strain, we introduced out-of-plane motion. The design variables are parameterized into normalized bulk material densities. The objective functions are the minimum compliance and the maximum eigenvalues and the constraint is the allowable volume. Through several numerical examples, the developed DSA method is verified to yield very accurate sensitivity results compared with the finite difference ones and the topology optimization yields physically meaningful results.