• Title/Summary/Keyword: complex analysis

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An Analysis on the Factors Affecting the Level of Resident's Satisfaction in Certified Environment Friendly Apartment (친환경 공동주택 인증단지의 주거 만족도 영향요인 분석)

  • Lee, Geun-Hee;Park, Hee-Seog;Jo, Yong-Sung
    • Journal of the Korean housing association
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    • v.21 no.4
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    • pp.121-128
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    • 2010
  • Many business enterprises in domestic housing industry are focusing on the development of environment friendly apartment complex to strengthen the competitiveness by upgrading their company's image through differentiation of the qualities and satisfying the customer's needs. Many apartment complex have achieved temporary or real certification by green building certification system, but there weren't enough studies on how much residents are satisfied by their certified complex. In this study, we want to clarify the factors of resident's satisfaction level in certified environment friendly complex by comparing the social and economical characteristics of resident. For this study, we chose and compare 4 environment friendly apartment complex considered to be built by the best environmental way in metropolitan area, and 4 other apartment complex which are also considered to be similar in terms of the condition of location and period of stay.

Crystallization and preliminary X-ray analysis of API5-FGF2 complex

  • Bong, Seoung Min;Lee, Byung Il
    • Biodesign
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    • v.6 no.4
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    • pp.92-95
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    • 2018
  • API5 is a unique oncogenic, non-BIR type IAP nuclear protein and is up-regulated in several cancers. It exerts several functions, such as apoptosis inhibition, cell cycle progression, cancer immune escape, and anticancer drug resistance. Although structural studies of API have revealed that API5 mediates protein-protein interactions, its detailed molecular functions remain unknown. Since FGF2 is one of API5's major interacting proteins, structural studies of the API5-FGF2 complex will provide insight into both proteins' molecular function. We overexpressed and purified API5 and FGF2 in Escherichia coli and crystallized the API-FGF2 complex using polyethylene glycol (PEG) 6000 as a precipitant. Diffraction data were collected to a $2.7{\AA}$ resolution using synchrotron X-rays. Preliminary diffraction analysis revealed that the API5-FGF2 complex crystal belongs to the space group $P2_12_12_1$ with the following unit cell parameters: a = 46.862, b = 76.523, $c=208.161{\AA}$. One asymmetric unit with 49.9% solvent contains one API5-FGF2 complex. Molecular replacement calculation, using API5 and FGF2 coordinates, provided a clear electron density map for an API5-FGF2 complex.

Application of Capillary Electrophoresis for Quality Control Analysis of Complex Medicine (모세관 전기영동 분석법의 복합약물제제의 품질관리 분석에 응용을 위한 연구)

  • Heo, Yoo-Jeong;Lee, Kong-Joo
    • YAKHAK HOEJI
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    • v.41 no.5
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    • pp.539-546
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    • 1997
  • Capillary electrophoresis (CE) is perceived as an attractive tool for the analysis of pharmaceuticals and biological materials because of their high separation efficiency, easy separation and low running cost. New concept of micellar electrokinetic capillary chromatography (MECC) expanded the application of CE to the separation of neutral molecules. Validation of CE as an analytical technique for quality control of pharmaceuticals should be confirmed by quantitative analysis and the peak confirmation. In this study, the quantitative analyses of various types of neutral, acidic and basic components (acetaminophen, caffeine, ascorbic acid, riboflavin, thiamine, chlorpheniramine, phenylpropanolamine, dl-methylephedrine and dextromethorphan) in complex cold medicines have been accomplished using CE. Combined methods of MECC using SDS and capillary zone electrophoresis lowering the pH of running buffer were adopted to determine the ingredients in capsule type or liquid formula complex medicines without particular sample pretreatment. The results indicate that CE is a promising technique for quality control analysis of pharmaceuticals as a validation method.

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Synthesis and Structural Characterization of the One-Dimensional Cadmium(II) Complex with Thiocyanate and 4-Methylimidazole Ligands (티오시아네이트 및 4-메틸이미다졸 리간드로 구성된 1차원 카드뮴(II) 착물의 합성과 구조 분석)

  • Moon, Hyoung-Sil;Kim, Chong-Hyeak;Lee, Sueg-Geun
    • Analytical Science and Technology
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    • v.14 no.6
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    • pp.535-539
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    • 2001
  • One-dimensional coordination polymer of cadmium(II) complex, $[Cd(SCN)_2(C_4H_6N_2]_n$, has been prepared and characterized by X-ray single crystallography. Structure analysis reveals that each cadmium(II) atom is six-coordinated in distorted octahedral fashion with $CdS_2N_4$ composition. $CdS_2N_4$ composition contains two S and two N atoms from four thiocyanates and tow N atoms from two 4-methylimidazole ligands. Central cadmium(II) atoms are run in parallel to the a-axis and are doubly bridged with neighboring cadmium(II) atoms by the thiocyanate and isothiocyanate ligands. Thus, this complex has a one-dimensional polymer structure in which the 4-methylimidazole is in the trans conformation.

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Detection of phenobarbital adulteration in dietary supplements: simultaneous analysis of 16 sedative-hypnotics and sleep-inducers by ultra-high-performance liquid chromatography with UV detection (UPLC-UV) and quadruple Orbitrap mass spectrometry (Q-Orbitrap-MS)

  • Lee, Ji Hyun;Choi, Ji Yeon;Park, Hanna;Min, Ah Young;Kim, Nam Sook;Park, Seong Soo;Park, Sung-Kwan;Kang, Ho-il
    • Analytical Science and Technology
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    • v.32 no.1
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    • pp.24-34
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    • 2019
  • The safety of food is occasionally questionable, as there have been some reports of products contaminated with illegal adulterants. In this study, the presence of 16 sedative-hypnotics and sleep inducers in dietary supplements was determined by ultra-high-performance liquid chromatography with UV detection (UPLC-UV) and quadruple Orbitrap mass spectrometry (Q-Orbitrap-MS). The UPLC method was validated, providing a linearity (R2) of more than 0.999, and LODs and LOQs that ranged from 0.2 to 0.5 and 0.6 to $1.5{\mu}g\;mL^{-1}$, respectively. The repeatabilities were 0.2-8.4 % (intra-day) and 0.3-4.5 % (inter-day), and the accuracies were 89.0-117.0 % (intra-day) and 87.8-111.9 % (inter-day). The mean recoveries of the spiked samples ranged from 98.7 to 107.3 %. The relative standard deviation (%RSD) of the stability was less than 2.4 %. Using the developed method, one sedative-hypnotic compound, phenobarbital, was detected in one of the nineteen samples tested. In addition, the major characteristic fragment ions of each target compound were confirmed using Q-Orbitrap-MS for higher accuracy. Monitoring the presence of these 16 sedative-hypnotics and sleep inducers in dietary supplements should be pursued in the interest of human health, and the results of this study confirmed that the developed method has value for this application.

Morphological multivariate analyses of Isodon excisus complex (Lamiaceae) in Korea

  • Kim, Sang-Tae;Ma, Youn-Ju
    • Korean Journal of Plant Taxonomy
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    • v.41 no.3
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    • pp.223-229
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    • 2011
  • The taxonomy of the Isodon excisus complex has been ambiguous and problematic because the morphological characters, especially characters related to the leaf distinguishing subgroups of the complex in the original descriptions, are variable. To elucidate the taxonomic structure of the I. excisus complex in Korea, 34 characters were measured from 70 OTUs representing different locations and analyzed by principal component analysis (PCA). The analysis showed that principle component axis 1, 2, 3 (PC1, PC2, PC3) represents 52.0% of the total variance and characters showing high loading values for PC1 were leaf shape, density of non-glandular hairs on the lower surface of the leaf, and characters related to the teeth of the leaf. The length of apical tooth and the angle between two widest points of the leaf were highly correlated to PC2 and PC3, respectively. Three-dimensional scatter plotting of OTUs for PC1, PC2, and PC3 axis showed that the areas of previously recognized three subgroups of I. excisus completely overlapped. Our result supported that just one taxon, I. excisus var. excisus, should be recognized in the complex at the variety level.

A Study on the Characteristics of Leisure Facilities and Needs of Residents in Apartment Complex (공동주택단지 내 여가시설 특성 및 거주자 요구에 관한 연구)

  • Shin Hwa Kyoung
    • Journal of Families and Better Life
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    • v.22 no.6 s.72
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    • pp.89-97
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    • 2004
  • The purpose of this study was to investigate the characteristics of leisure facilities and to examine residents' needs for leisure facilities in apartment complex. The questionnaire survey and content analysis were used. The Data for content analysis were 476 site plans, and the subjects of questionnaire survey were 673 residents lilving in 35 apartment complex. Frequency, Percentage, and mean, ANOVA-A, x^{2}-test, and multiple regression were used for data analysis. The major results were as follows. 1) Facilities for children play, and senior, sports facilities, community center, green area, and resting place were included in leisure facilities in apartment complex. These facilities were different according to complex site and built-period. 2)The degree of satisfaction of leisure facilities was lower than neutral. The satisfaction of leisure facilities related with diversity of leisure facilities and program, and poor environment. 3) Subjects needed the facilities recommended in housing act including diverse leisure facilities such as sports center and resident's self government facilities. And they needed divers facilities for sports. 4) In terms of location, they needed leisure facilities which was closer to their house.

Electrochemical Polymerization of Ruthenium(II) Complex and Application to Acetaminophen Analysis

  • Kannan, Sethuraman;Son, Jung-Ik;Yang, Jee-Eun;Shim, Yoon-Bo
    • Bulletin of the Korean Chemical Society
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    • v.32 no.4
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    • pp.1341-1345
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    • 2011
  • A novel ruthenium(II) complex, [$RuCl_2(DMSO)_2$(PhenTPy)] has been synthesized by the condensation of $RuCl_2(DMSO)_4$ with (1-(1,10-phenanthrolinyl)-2,5-di(2-thienyl)-1H-pyrrole)[PhenTPy] in $CHCl_3$ solution. The [$RuCl_2(DMSO)_2$(PhenTPy)] complex modified electrode was fabricated through the electropolymerization of the monomer in a 0.1 M tetrabutylammonium perchlorate (TBAP)/$CH_2Cl_2$ solution, to take advantage of the electronic communication between metal ion center by the conjugated backbone. The UV-visible spectroscopy (UV), mass spectrometry (MS), and cyclic voltammetry (CV) were employed to characterize the [$RuCl_2(DMSO)_2$(PhenTPy)] complex and its polymer (poly-Ru(II)Phen complex). The poly-Ru(II)Phen complex modified electrode exhibited an electrocatalytic activity to the oxidation of acetaminophen and the catalytic property was used for the analysis of acetaminophen at the concentration range between 0.09 and 0.01 mM in a phosphate buffer solution (pH 7.0).

Trend Analysis of Complex Disasters in South Korea Using News Data (뉴스데이터를 활용한 국내 복합재난 발생 동향분석)

  • Eun Hye Shin;Do Woo Kim;Seong Rok Chang
    • Journal of the Korean Society of Safety
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    • v.38 no.6
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    • pp.50-59
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    • 2023
  • As the diversity of disasters continues to increase, the concept of "complex disasters" has gained prominence in various policies and studies related to disaster management. However, there has been a certain limitation in the availability of the systematic statistics or data in advancing policies and research initiatives related to complex disasters. This study aims to analyze the macro-level characteristics of the complex disasters that have occurred domestically utilizing a 30-year span of a news data. Initially, we categorize the complex disasters into the three types: "Natural disaster-Natural disaster", "Natural disaster-Social disaster", and "Social disaster-Social disaster". As a result, the "natural diaster-social disaster" type is the most prevalent. It is noted that "natual disaster-natural disaster" type has increased significantly in recent 10 years (2011-2020). In terms of specific disaster types, "Storm and Flood", "Collapse", "Traffic Accident", "National Infrastructure Paralysis", and "Fire⋅Explosion" occur the most in conjunction with other disasters in a complex manner. It has been observed that the types of disasters co-ocuuring with others have become more diverse over time. Parcicularly, in recent 10 years (2011-2020), in addition to the aforementioned five types, "Heat Wave", "Heavy Snowfall⋅Cold Wave", "Earthquake", "Chemical Accident", "Infectious Disease", "Forest Fire", "Air Pollution", "Drought", and "Landslide" have been notable for their frequent co-occurrence with other disasters. These findings through the statistical analysis of the complex disasters using long-term news data are expected to serve as crucial data for future policy development and research on complex disaster management.