• Korean Journal of Child Studies
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• v.27 no.2
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• pp.101-126
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• 2006

In this comparison of the relative effects of children's separation from their parents, socio-emotional adjustment was assessed by emotional and behavioral problems and emotional intelligence. Subjects were 502 elementary school children separated from their parents(162 in Yanbian and 340 in Korea) and their caregivers. Data analysis was by frequency, t-test, and multiple regression controlled by gender and grade in school. Caregivers living with children and their parenting efficacy were significant variables for the development of socio-emotional adjustment in Korean-Chinese children in Yanbian, but reasons for parent-child separation, caregivers' psychological and behavioral characteristics, and SES were significant variables for children in Korea. Implications are that regional differences should be considered in understanding and supporting the development of children's socio-emotional adjustment.

• Journal of Food Hygiene and Safety
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• v.37 no.5
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• pp.317-322
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• 2022

Corynebacterium pseudotuberculosis is the causative agent of caseous lymphadenitis (CLA), a chronic contagious disease in small ruminants. The prevalence of CLA has been reported to be >50% in Korean black goats. CLA is difficult to control due to a lack of efficient vaccines and treatment methods. Effective disinfection of the farm environment may be an alternative strategy for reducing the spread of C. pseudotuberculosis. The objective of this study was to evaluate the efficacy of commercial disinfectants against CLA. The six commercial disinfectants, largely composed of sodium dichloroisocyanurate, sodium hypochlorite, potassium monopersulfate triple salt, quaternary ammonium, citric acid, and copper sulfate, were tested against five different genotypes of C. pseudotuberculosis isolated from goat farms in Korea. Efficacy tests were performed in accordance with the disinfectant efficacy test guidelines recommended by the Animal and Plant Quarantine Agency of Korea with slight modifications. All disinfectants except for copper sulfate exhibited >99.99% killing efficacy under hard water conditions following 30 min of incubation, which is the recommended standard treatment time according to guidelines. The minimum bactericidal treatment time was evaluated by employing treatments for durations of 1, 5, and 15 min. The most effective compounds under hard water conditions were sodium dichloroisocyanurate, potassium monopersulfate triple salt, and sodium hypochlorite, exhibiting >99.99% killing efficacy after 1 min of treatment. In the aqueous solution forms, citric acid and the quaternary ammonium compound were the most effective, but required at least 5 min to kill >99.99% of the bacteria. The current study characterizes the killing efficacy of six commercial disinfectant active compounds against C. pseudotuberculosis. Thus, this study provides essential information regarding the efficacy of the disinfectants used to control CLA in goat farms.

• Clinical and Experimental Pediatrics
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• v.48 no.1
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• pp.55-62
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• 2005

Purpose : We compared the therapeutic efficacy of lamivudine and alpha-interferon in children with chronic hepatitis B two years after the initiation of treatment, so that we could verify the safety and long term efficacy of lamivudine in children. Methods : We prospectively studied 44 children(32 male and 12 female; age, 1-18 years, mean, 9 years) treated for chronic hepatitis B from September 1996 to June 2004 in Kyungpook National University Hospital in Korea. Twenty three children were treated with interferon, and 21 with lamivudine. Treatment efficacy was defined as the normalization of ALT and hepatitis B virus(HBV) DNA levels, loss of HBsAg and HBeAg seroconversion at two years after the initiation of treatment. Results : Among the 23 children treated with interferon, the ALT level normalized in 10 children(43 %) and HBV DNA was undetectable in 12 children(52%). HBsAg was undetectable in one child (4 %) and HBeAg seroconversion occurred in nine children(39%) two years after the initiation of treatment. In comparison, among the 21 children treated with lamivudine, ALT normalized in 20 children (95%), HBV DNA in 19(90%), HBsAg in 5(24%), and HBeAg seroconversion occurred in 13(62%). Above all, in the lamivudine treated group under the age of seven, HBeAg and HBsAg seroconversion occurred in six(75%) and five(63%) out of the eight children respectively, which showed superior HBsAg seroconversion rate if treated in preschool aged children. Conclusion : We believe that the therapeutic efficacy of lamivudine in children with chronic hepatitis B could be better than interferon with fewer side effects, especially in preschool aged children.

• Journal of Haehwa Medicine
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• v.4 no.1
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• pp.357-371
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• 1995

We have completed a study to measure the contents of glucose, BUN, creatinine. LDH, and T-protein with respect to a fatigued condition in the bloods of rats which a constant swimming is loaded and to measure the maximun swimming time of mice The test has been carried out as a part of the basic study on the efficacy of B. E. P. (Biological Energy Projector) for emitting a light energy having a specific wavelength out of far-infrared rays. As a result. We have reached the following conclusions: 1. At testing of mice's maximun swimming time, all of B.E.P.(2. 4. 8. 24hrs) treated group have been increased in comparison with the control group, but only 24hrs-B.E.P. treated group significantly increased during 4 weeks. 2. The contents of glucose, BUN. creatinine, LDH, and T-protein measured immediately after the swimming of mice have been distinctly changed but not been significantly changed at their increase and decrease in comparison with the control group. 3. At 3rd day out of the swimming loading, the contents of glucose in the blood serum of the white rat have been distinctly increased in comparison with the control group. And 24hrs-B.E.P treated group surpassed 8hrs-B.E.P. treated group. 4. At 1st and 3rd day, the contents of creatinine in the blood serum of the white rat have been distinctly increased at B.E.P. (8, 24hrs) treated groups in comparison with the control group and have been recovered to the condition of the normal group. 5. After three days, the contents of BUN in the blood serum of the white rat have been significantly decreased in B.E.P.(8, 24hrs) treated groups at 3rd day in comparison with the control group and have been recovered to the condition of the normal group. 6. The contents of LDH in the blood serum of the white rat have been decreased in B.E.P.(8, 24hrs) treated groups at 3rd day in comparison with the control group, in particular 24hrs-B.E.P. treated group has been decreased distinctly than the normal group. 7. The contents of T-protein in the blood serum of the white rat have been distinctly increased in B.E.P. (8, 24hrs) treated groups at 3rd day in comparison with the control and normal group. As the above results, it has been proved that the execise of mice and the fatigue metabolism of rats were influenced by the light energy emitted the B.E.P., and it has been also proved that the external stimulation could be used as a preferable stimulative factor for the biological metabolism. If the clinical training and study are positively achieved, the B.E.P. would be used as curative means and preventive measures for helping human body.

• Korean Journal of Occupational Health Nursing
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• v.7 no.1
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• pp.20-32
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• 1998

This study was conducted investigate the practice of health promoting behavior in hospital workers. The subjects for this study were 529 hospital war kern working in four university hospitals in the Kyong-in area. Data were collected by using constructed questionnaires from January 13. 1997 to February 24, 1997, analyzed by descriptive statistics, ANOVA and $Scheff{\acute{e}}$ comparison test, Pearson's correlation coefficient and stepwise multiple regression. The results were as follows; 1. The mean score of health promoting behavior for hospital workers was 2.40. The health promoting behavior in relation to the characteristics of the subjects varied significantly according to sex, age, career, religion and number of children. 2. The mean score of health perception was 3.29. The health perception in relation to the characteristics of the subjects showed no statistical discrepancy. 3. The mean score of self-esteem was 3.80. The self-esteem in relation to the characteristics of the subjects varied significantly according to sex, age, occupation, educational background, religion and marital status. 4. The mean score of self-efficacy was 69.63. The self-efficacy in relation to the characteristics of the subjects sailed significantly according ding to sex, age, occupation, career, religion, marital status and number of children. 5. The mean score of internal health locus of control was 2.88. The internal health locus of control in relation to the characteristics of the subjects varied significantly according to sex and occupation. The mean score of chance health locus of control was 2.08. The chance health locus of control in relation to the characteristics of the subjects varied significantly according to occupation and religion. The mean score of powerful others health locus of control was 2.35. The powerful others health locus of control in relation to the characteristics of the subjects varied significantly according to career, educational background, marital status and number of children. 6. Performance in health promoting behavior was significantly correlated with self-esteem, self-efficacy, powerful others health locus of control, health perception and internal health locus of control. 7. The combination of self-esteem, powerful others health locus of control, health perception, self-efficacy, internal health lot-us of control, age and marital status explained 45.72% of the variance of likelihood to engage in health promoting behavior.

• The Journal of the Korea Contents Association
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• v.11 no.1
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• pp.254-265
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• 2011

The purpose of this study was to examine the effect of difficult endotracheal intubation education in the 119 rescue services. The subjects in this study were 60 members of the 119 rescue services that was under the umbrella of the Fire Service Headquarters of J province. A SPSS 14.0 program was utilized to find out the effect of tough tracheal intubation education on their relevant knowledge, self-confidence, academic self-efficacy and technical Performance in consideration of general characteristics. The findings of the study were as follows: 1. They showed a significant improvement in all the knowledge, self-confidence, academic self-efficacy and technical Performance after they received that education. 2. As for connections between general characteristics and knowledge before and after that education, there were significant differences in their knowledge according to gender and career of working in the hospital, and their rank and career of working in the hospital made a significant differences to their self-confidence. Their academic self-efficacy significantly differed with rank, career of working in the hospital and academic credential. There were significant gaps among them technical Performance Case 1 according to career of working in the 119 rescue services, and technical Performance Case 2 significantly varied with age and academic credential. There were significant gaps in technical Performance Case 3 according to career of working in the 119 rescue services and career of working in the hospital after that education was provided, and technical Performance Case 4 significantly varied with age and rank before and after the education was conducted. In conclusion, the kind of education programs that aim at stirring up the interest of the 119 rescue services in advanced airway and helping the members learn about tracheal intubation accurately with confidence is urgently required.

• The Journal of Korean society of community based occupational therapy
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• v.10 no.3
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• pp.27-35
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• 2020

Objective : This study was to examine the effects of general characteristics and fall efficacy on health care program needs through a comparative analysis of general characteristics and health care program needs for the elderly. Methods : In this study, we analyzed data from 118 elderly people with t-test and ANOVA for comparison of fall effectiveness and health care program requirements and with regression for general characteristics and effects of fall effectiveness on health care program needs. Results : The results were as followed: First, there was a significant difference in gender(p=.00), age (p=.00),educational background(p=.00), and existence of spouse(p=.00), and no significant difference in income(p=.17) based on fall efficiency according to the general characteristics. There was a significant difference in gender(p=.00), age(p=.00), educational background(p=.00), and income(p=.00) and no significant difference in existence of spouse (p=.46) based on health care program needs according to the general characteristics. Second, it was shown that the higher age, the higher the income, the higher the effectiveness of the fall, and in case of woman, the more significant the effect of the exercise program had.. The explanation was 56 percent. Third, the higher the age, the higher the income, and the higher the fall efficiency, the more meaningful the cognitive program demand. The explanation was 48 percent. Conclusion : The data from this study showed the importance of fall efficacy in older people with significantly higher risk of falls than in other age groups, and the need for exercise and cognitive management programs to prevent falls.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.1
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• pp.9-21
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• 2021

In this study, the difference between the preservative efficacy test (PET) used for water dispersion formulations and PCPC (personal care products council) guidelines alternative test method, direct contact membrane method, and surface mold test should be studied to determine what should be considered during preservative efficacy test of water non-dispersible formulations. We conducted improved PETs when using the alternative test method compared with the test methods used for stick and pressed powder. There was no significant improvement between water-in-silicon emulsions and loose powder using alternative test methods. When we checked the results of the presence and absence of the preservative system for each product, we could see that there were differences in testing methods. As a result, improved levels of results could be obtained using both existing and alternative test methods when measuring preservatives for water non-dispersible formulations. In addition, in the case of stick and pressed powder, the results were more effective when the preservative test method applied to the consumer's method of use was applied.

• Molecules and Cells
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• v.47 no.1
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• pp.100005.1-100005.15
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• 2024

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease with a complex genetic basis, presenting both in familial and sporadic forms. The hexanucleotide (G₄C₂) repeat expansion in the C9orf72 gene, which triggers distinct pathogenic mechanisms, has been identified as a major contributor to familial and sporadic Amyotrophic lateral sclerosis cases. Animal models have proven pivotal in understanding these mechanisms; however, discrepancies between models due to variable transgene sequence, expression levels, and toxicity profiles complicate the translation of findings. Herein, we provide a systematic comparison of 7 publicly available Drosophila transgenes modeling the G₄C₂ expansion under uniform conditions, evaluating variations in their toxicity profiles. Further, we tested 3 previously characterized disease-modifying drugs in selected lines to uncover discrepancies among the tested strains. Our study not only deepens our understanding of the C9orf72 G₄C₂ mutations but also presents a framework for comparing constructs with minute structural differences. This work may be used to inform experimental designs to better model disease mechanisms and help guide the development of targeted interventions for neurodegenerative diseases, thus bridging the gap between model-based research and therapeutic application.

• Journal of Environmental Policy
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• v.3 no.2
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• pp.31-57
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• 2004

Attempts were made to compare and analyze the policies of the United States, the United Kingdom, the Netherlands, Germany and Denmark concerning Korea's major problems associated with legal liability of the contaminated sites. These countries were chosen from a feasible preliminary analysis of 18 countries of the EU and the U. S. The major problems were revealed based on the analysis of Korean legacy and legislation, which are summarized as follows i) lack of clear detailed technical and legal guidance to determine the responsible party or parties of contaminated sites, ii) no distinction between the strict and non strict legal liability of innocent land owners, iii) no clearly set limit on retroactive legal liability. Comparison of the policies of countries chosen suggested improvements regarding these major problems as follows: i) activating national and international research on soil contamination prevention policy, ii) arranging distinct legal regulation between strict and non strict liability criteria, iii) establishing the limits on innocent and non strict liability, iv) establishing methodology and process of legal liability distribution and compensation, and v) establishing a legal process to redeem any benefit derived from remediation of contaminated sites with the public budget. Our policy suggestions above are not yet conclusive due to a lack of policy implementation simulation. Additional research is needed on aspects of social, economic and long term effects of the proposed policy directions. Nevertheless, application of the policy suggestions of this research would increase the efficacy of Korean policy regarding the survey and remediation of the potentially contaminated sites.