• 대한의용생체공학회:의공학회지
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• 제29권4호
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• pp.329-336
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• 2008

Recently, causality analysis of source time series extracted from EEG or MEG signals is becoming of great importance in human brain mapping studies and noninvasive diagnosis of various brain diseases. Two approaches have been widely used for the analyses: one is independent component analysis (ICA), and the other is multiple signal classification (MUSIC). To the best of our knowledge, however, any comparison studies to reveal the difference of the two approaches have not been reported. In the present study, we compared the performance of the two different techniques, ICA and MUSIC, especially focusing on how accurately they can estimate and separate various brain electrical signals such as linear, nonlinear, and chaotic signals without a priori knowledge. Results of the realistic simulation studies, adopting directed transfer function (DTF) and Granger causality (GC) as measures of the accurate extraction of source time series, demonstrated that the MUSIC-based approach is more reliable than the ICA-based approach.

• Journal of Multimedia Information System
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• 제4권4호
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• pp.233-238
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• 2017

Automatic identification of disease in plants from their leaves is one of the most challenging task to researchers. Diseases among plants degrade their performance and results into a huge reduction of agricultural products. Therefore, early and accurate diagnosis of such disease is of the utmost importance. The advancement in deep Convolutional Neural Network (CNN) has change the way of processing images as compared to traditional image processing techniques. Deep learning architectures are composed of multiple processing layers that learn the representations of data with multiple levels of abstraction. Therefore, proved highly effective in comparison to many state-of-the-art works. In this paper, we present a plant disease identification methodology from their leaves using deep CNNs. For this, we have adopted GoogLeNet that is considered a powerful architecture of deep learning to identify the disease types. Transfer learning has been used to fine tune the pre-trained model. An accuracy of 85.04% has been recorded in the identification of four disease class in Apple plant leaves. Finally, a comparison with other models has been performed to show the effectiveness of the approach.

• 약학회지
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• 제47권3호
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• pp.135-141
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• 2003

The majority of table salts are bay salts and chemical salts. However, chemical salts are known to have a different composition in biological electrolytes and quality of bay salts are getting worse due to the increasing seawater contamination. These facts may have led to the increasing usage of various health-promoting salts. Bamboo salt was introduced in 1986 as a solution to replace table salts to eliminate those detrimental effects, to promote general health and to treat diseases. Although all bamboo salts from different manufacturers have been used for the same health and medical purposes, each manufacturer utilizes different manufacturing process. The ICP analysis was used to study the changes of elemental contents in a bamboo salt during the manufacturing steps as well as these contents in various bamboo salts and other salts. After the first step, contents of Li and Sr in the bamboo salt were increased in comparison with those in the raw material, bay salt. As the next steps continued, contents of K, Ca and Ba were continuously increased. At the completion of the final step, contents of Mg and P were decreased and those of Cu, Mn and Mo were gradually increased. Bamboo salts contained lower contents of Mg, Al, B, and P, but higher contents of K, Ca, Fe, Cu, Mn, Zn, Li, Ba, Sr and Mo than bay salt.

• 한국임상약학회지
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• 제31권3호
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• pp.216-230
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• 2021

Objective: Taking action on health inequalities starts with the production of information laying out the problems of inequalities, but Korean society has no national database to view related data at a glance. This study aimed to compare Korean national database with the Public Health Profile (PHP), a health inequality database of the UK. Methods: Data were collected from the websites of government and relevant organizations in the both countries between March and August 2020, which was updated in August 2021. Two themes including Co-occurring substance misuse and mental health issues in mental health and INteractive Health Atlas of Lung conditions in England were selected for comparison in terms of data accessibility, data usability and data visualization. Results: The British PHP is being served on a web-based platform, Fingertips. The data collected at the regional level were presented on 31 health inequality themes. The data are displayed at a level that can be compared between comparable communities, and visualized into various tables and figures. Comparable Korean data were scattered in several themes and websites, and mostly provided as a 17 administrative region base, which was too vast to make a meaningful comparisons. Conclusion: The findings proposed several considerations which could be useful for establishing a database of health inequality in the Korean society.

• 한국물환경학회지
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• 제27권1호
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• pp.1-8
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• 2011

네팔의 천연 수자원은 풍부한 편이나 모든 인구가 안전하고 깨끗한 식수를 공급받고 있지는 못한 상황이다. 또한, 폐수 처리에 대한 상황 역시 매우 열악한 상태라고 할 수 있다. 최근, 도시로의 인구 유입이 증가함에 따라 안전한 물의 공급 및 공중 위생에 대한 관심이 증대되고 있으나, 수인성 질환의 발병률은 여전히 높은 상황이다. 본 논문에서는 네팔의 수질 오염, 식수에서의 비소 오염, 폐수 처리, 그리고 대중의 건강에 대한 수질 오염의 영향 등에 대해 검토하였다. 또한, 폐수 처리와 연관된 규제와 관련하여 한국의 상황과 비교하여 양국의 상황을 비교 고찰하였다. 이러한 내용들에 의거하여 대중의 건강 증진을 위한 현존 문제점들의 해결 방안들을 제시하였다.

• Physical Therapy Rehabilitation Science
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• 제12권2호
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• pp.155-160
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• 2023

Objective: The purpose of this study is to confirm a comparison of bag weight and applied location change on plantar pressure and gait parameters (stride time, stride length, cadence) of the 20s students. Design: One group cross-sectional design Methods: The subjects were measured in each condition. Each condition was no carrying a bag, carrying a 3kg bag, and a 6kg bag on the right shoulder, and walked on the gait analyzer. After the location of the bag was changed, measured when a 3kg backpack and a 6kg backpack was each carried on the back while walking. Results: There was a statistically significant difference in plantar pressure according to bag weight when carried on the right shoulder (p<0.05). As a result of the post-hoc analysis, carrying a 6kg bag was a significant difference between no carrying a bag and carrying a 3kg bag (p<0.05). There was no statistically significant difference in changes in stride time, stride length, and cadence. There was no statistically significant difference in plantar pressure and gait parameters according to backpack weight. Conclusions: As a result of this study, it is thought that it will be possible to present a method for the application of the correct bag on location and weight in 20s students, and to prevent and reduce muscle musculoskeletal system diseases caused by incorrect bag wearing.

• 한국의학물리학회지:의학물리
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• 제20권4호
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• pp.235-243
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• 2009

다양한 간 질환에 Ferucarbotran (SPIO)과 Gd-EOB-DTPA (Primovist) 조영제를 사용하여 자기공명영상 상에서 비교하여 간 질환의 특성 및 검출 과 그 질환에 따른 조영제 흡수관계를 알아보고자 한다. 실험대상은 국소 간 병변을 가진 50명의 환자 중 남자 25명, 여자 25명으로 평균나이는 50세이었다. 사용된 장비와 코일은 3.0T (General Electric Medical System, Excite HD) 자기공명영상장치와 8채널 채부코일이었다. 질환과 조영제 흡수관계를 비교하기 위하여 사용된 펄스 시퀀스는 Liver aquisition with volume acceleration (LAVA)와 Multi-Gradient rapid Echo (MGRE)이었다. 모든 검사기법은 일정한 데이터를 획득하기 위하여 Ferucarbotran (SPIO) 및 Gd-EOB-DTPA (Primovist) 조영제를 주입 전 후에 같은 위치를 선정하여 검사를 시행했다(p<0.05). 검사 결과는 Ferucarbotran와 Gd-EOB-DTPA의 대조도대 잡음비는 간세포암(HCC, 16 cases)이 $3.08{\pm}0.12$과 $7.00{\pm}0.27$이었다. 과다형성결절(Hyperplastic Nodule, 7 cases) 질환은 $3.62{\pm}0.13$, $2.60{\pm}0.23$, 전이(Metastasis, 13 cases)는 $1.70{\pm}0.09$, $2.60{\pm}0.23$, 초점성 결절성 과증식(Focal Nodular Hyperplasia, 6 cases)질환은 $2.12{\pm}0.28$, $5.86{\pm}0.28$, 농양(Abscess, 8 cases)은 $4.45{\pm}0.28$, $1.73{\pm}0.02$이었다. 또한, 각 질환에 대한 진단적 수행을 위해 ANOVA 검증을 하였다(p<0.05). 결론적으로, 두 조영제 효과로 2개 검사기법 모두가 간질환의 특성 및 검출과 그 질환에 따른 조영제 특성을 잘 보여주었다.

• PNF and Movement
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• 제20권3호
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• pp.341-349
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• 2022

Purpose: The purpose of this study is to compare the muscle activity of the hip abductors and the ratio between the hip abductor muscle group according to the range of hip abduction during the clam exercise. Methods: This study was conducted on 18 healthy men in their aged 20 to 29 who had not been diagnosed with spine-related diseases. The subjects performed a clam exercise without rotation of the pelvis in a state of 60° hip flexion and 90° knee joint flexion in the side-lying position. Using Myomotion equipment and EMG, the muscle activity of the hip abductor muscles and the activity ratio between the hip abductor muscle group were measured during the clam exercise by dividing the range into initial, mid-range, and terminal sections. Repeated measures analysis of variants was employed to compare the activity and use of hip abductor muscles according to range of motion during the clam exercise. Results: Gluteus medius muscle activation was significantly increased in the comparison of muscle activity in the initial, mid-range, and terminal sections of hip abduction. Tensor fasciae latae muscle activation was significantly increased in the comparison of muscle activity in all range of motion sections as well. The gluteus medius-tensor fasciae latae muscle activation ratio was significantly increased in the terminal section compared to the initial section. Conclusion: The gluteus medius and tensor fasciae latae had higher muscle activities as they approached the terminal section during the clam exercise, and the hip abduction activity ratio of the gluteus medius and tensor fasciae latae was higher as the range of motion approached the terminal section.

• Molecules and Cells
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• 제47권1호
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• pp.100005.1-100005.15
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• 2024

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease with a complex genetic basis, presenting both in familial and sporadic forms. The hexanucleotide (G₄C₂) repeat expansion in the C9orf72 gene, which triggers distinct pathogenic mechanisms, has been identified as a major contributor to familial and sporadic Amyotrophic lateral sclerosis cases. Animal models have proven pivotal in understanding these mechanisms; however, discrepancies between models due to variable transgene sequence, expression levels, and toxicity profiles complicate the translation of findings. Herein, we provide a systematic comparison of 7 publicly available Drosophila transgenes modeling the G₄C₂ expansion under uniform conditions, evaluating variations in their toxicity profiles. Further, we tested 3 previously characterized disease-modifying drugs in selected lines to uncover discrepancies among the tested strains. Our study not only deepens our understanding of the C9orf72 G₄C₂ mutations but also presents a framework for comparing constructs with minute structural differences. This work may be used to inform experimental designs to better model disease mechanisms and help guide the development of targeted interventions for neurodegenerative diseases, thus bridging the gap between model-based research and therapeutic application.

• 보건교육건강증진학회지
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• 제30권4호
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• pp.111-123
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• 2013

Objectives: This study aimed to share with experiences of a demonstration program based on a community for prevention and management of hypertension and diabetes mellitus, and to supply the evidence of accessible strategies within the community through the public-private partnershipin the near future. Methods: This study case was "the program of registration and management of hypertension and diabetes mellitus patients" which was conducted in Hogncheon-gun in Gangwon-province, 2012. Results: The infrastructure of this center was constructed with the public-private sector partnership according to the basic model of demonstration program since November, 2012. So, the total registered rate of hypertension and diabetes mellitus patients were 26.6% in comparison with suspected patients (to the result of 2011 Korea National Health and Nutrition Examination Survey), 37.8% in comparison with the real number of outpatient (to the claims data of 2011 Branch Honcheon-gun, National Health Insurance Corporation), and 107.8% in comparison with the project goal, sequentially. To the patients who were not treated for 30 and 60 days among the registered patients, a recall service was conducted. Through this intervention, it was monitored that this program has enhanced the consecutive treatment rate of the registered patients. Conclusions: To improve the continuous management of hypertension and diabetes mellitus patients, we are gotten to know that the community need the joint participation and mutual cooperation with public-private sector partnership.