• 한국정보시스템학회지:정보시스템연구
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• 제32권3호
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• pp.183-203
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• 2023

Purpose The purpose of this study is to examine the current operational status and problems of the Public Warning System (PWS) in China, and to propose feasible solutions to improve the performance and efficiency of the PWS through a comparative analysis with the Cell Broadcast Service (CBS)-based disaster SMS system adopted by other developed countries in the world. Design/methodology/approach In this study, the characteristics of PWS using SMS, applications, and CBS, respectively, are analyzed in detail, and compared and analyzed in terms of convenience, standardization, data security, speed, and location accuracy. In addition, CBS-based PWS in developed countries, such as U.S., E.U., Korea and Japan, were studied and their performance on key criteria was evaluated. Findings Based on the results of the study, the problems of China's PWS are summarized and recommendations are made to improve the PWS through the introduction of CBS technology. To this end, specific improvement measures are proposed in terms of the application of CBS technology, system construction and operation, and improvement of data security. In addition, the comparative analysis of PWSs in other developed countries is conducted to provide reference for the direction of PWS's improvement.

• 산업융합연구
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• 제20권7호
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• pp.21-30
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• 2022

본 연구는 기업의 디지털트랜스포메이션(digital transformation) 분야에서 가장 우선하는 클라우드 기반 회계정보시스템의 성공적 도입에 영향을 미치는 주요 요인을 탐색하는데 그 주안점을 두고 있다. 따라서 기업의 클라우드 현황과 관련 선행연구를 토대로 이론을 종합하였으며, 기업의 주요 성과 요인을 조직적 요인과, 비즈니스 업무 영역, 그리고 기술적 시스템 요인으로 구분하여 조사 분석하였다. 연구분석 방법은 클라우드 기반 회계정보시스템이 도입 초기인 점을 고려하여 전문가 패널을 대상으로 델파이(delphi method)분석 기법을 통해 주요 성공 요인을 중요도에 따라 순위를 정하고, 계층적분석(AHP)방법을 통해 각 주요 요인별 상호 중요도 분석을 통해 최종적으로 주요 성과변수를 탐색하였다. 분석결과 조직적 요인으로는 기업의 지속성과, 기업 운영적 요인은 비니니스 업무 솔루션, 그리고 시스템 확성성 요인으로 분석 되었다. 본 연구는 향후 많은 기업들이 주목하고 있는 클라우드 기반 회계정보시스템의 도입과 운영에 대한 초기 도입 전략과 운영에 추가적인 유용한 정보를 제공할 수 있을 것이다.

• Journal of Korea Trade
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• 제23권6호
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• pp.113-130
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• 2019

Purpose - This paper investigates applicability of blockchain based bill of lading under the current legal environment. Legal requirements of electronic bill of lading will be analyzed based on the Rotterdam Rules and recently enacted UNCITRAL Model Law on Electronic Transferable Records. Using comparative analysis with the previous registry model for electronic bill of lading, this paper examines the advantages of blockchain based bill of lading. Design/methodology - This research reviewed previous efforts for dematerializing bill of lading with its limitation. Main features of blockchain technology which can make up for deficiencies of registry model also be investigated to analyze whether these features can satisfy the requirements for the legal validity of the negotiable electronic transport record or electronic transferable records under the Rotterdam Rules and the MLETR. Findings - Main findings of this research can be summarized as follows: Blockchain system operated in an open platform can improve transparency and scalability in transfer of electronic bill of lading by assuring easy access for transaction. Distributed ledger technology of blockchain makes it more difficult to forge or tamper with transactions because all participants equally shares identical transaction records. Consensus mechanism and timestamp in a blockchain transaction guarantee the integrity and uniqueness of a transaction. These features are enough to satisfy the requirements of electronic transferable records under the Rotterdam Rules and MLTER. Originality/value - This study has significance in that it provided implications for the introduction of electronic bill of lading by analyzing whether the blockchain based electronic bill of lading model meets the legal requirements under the current legal system prepared prior to the introduction of blockchain technology, and by presenting the advantages of the blockchain based bill of lading model through comparative analysis with the existing registry model.

• 비교교육연구
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• 제21권2호
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• pp.51-73
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• 2011

호주는 오랫동안 주별 교육과정 체제를 유지해 왔으나, 최근 들어 국가교육과정 개발 체제를 구축하고 2011년 9월부터 새롭게 개발된 국가교육과정을 적용할 예정으로 있다. 호주가 왜 그토록 오랫동안 유지해 온 전통을 깨고 국가교육과정을 도입하려고 하는가는, 이와 반대의 흐름, 즉 교육과정 결정권을 국가로부터 점차 지방이나 학교로 이양시키고자 하는 우리의 맥락에서 볼 때 검토해 볼 필요가 있다. 특히 호주에서는 국가교육과정의 도입이 '교육혁명'의 일환으로 추진되고 있는 바, '혁명'에 상응하는 근본적인 변화가 국가교육과정에 어떻게 구현되어 있는지도 탐색해 볼 필요가 있다. 이 연구는 호주에서 처음으로 도입된 국가교육과정에 대해 그것의 개발 과정 및 주요 특징을 검토해 보는 데 주된 목적이 있다. 이를 위해 이 연구에서는 먼저 호주의 국가교육과정의 도입 및 개발 과정을 검토해 보고, 총론과 각론의 특징을 그 구조 중심으로 살펴본 뒤, 호주 국가교육과정 개발 사례가 우리나라 국가 교육과정 체제에 주는 시사점을 논의해 보았다.

• Journal of Plant Biotechnology
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• 제39권1호
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• pp.1-12
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• 2012

With the increasing advances in Brassicaceae genetics and genomics, considerable progress has been made in the transformation of Brassicaceae. Transformation technologies are now being exploited routinely to determine the gene function and contribute to the development of novel enhanced crops. $Agrobacterium$-mediated transformation remains the most widely used approach for the introduction of transgenes into Brassicaceae. In $Brassica$, the transformation relies mainly on $in$ $vitro$ transformation methods. Nevertheless, despite the significant progress made towards enhancing the transformation efficiencies, some genotypes remain recalcitrant to transformation. Advances in our understanding of the genetics behind various transformations have enabled researchers to identify more readily transformable genotypes for use in routine high-throughput systems. These developments have opened up exciting new avenues to exploit model $Brassica$ genotypes as resources for understanding the gene function in complex genomes. Although many other Brassicaceae have served as model species for improving plant transformation systems, this paper summarizes on the recent technologies employed in the transformation of both $Arabidopsis$ and $Brassica$. The use of transformation technologies for the introduction of desirable traits and a comparative analysis of these as well as their future prospects are also important parts of the current research that is reviewed.

• 한국멀티미디어학회논문지
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• 제11권1호
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• pp.96-105
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• 2008

디지털 미디어의 도입은 21세기를 데이터베이스 패러다임의 시대로 바꾸어놓았고 데이터베이스 패러다임은 애니메이션의 제작과정과 산업에 큰 변화를 불러일으켰다. 본래 애니메이션은 모든 이미지들을 새롭게 생성해야하는 특징을 가지고 있지만 디지털 기술의 도입으로 애니메이션을 위해 한번 제작된 이미지들은 데이터베이스 시스템에 원본 그대로 저장하게 되었고, 영구 보존된 데이터들은 변형과 합성을 통해 손쉽게 새로운 이미지들을 생성하게 되었다. 즉 디지털 애니메이션은 데이터베이스 시스템을 활용함으로써 무한 판본 생성의 시대를 맞이하며 효율성과 경제성을 추구하게 된 것이다. 이에 본 논문에서는 데이터베이스의 활용이 디지털 애니메이션의 창작기술을 어떻게 변화시켰는지를 구체적인 사례를 통해 살펴보고 그 의미와 함께 차세대 애니메이션의 미래를 전망해보고자 한다.

• 문화기술의 융합
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• 제7권2호
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• pp.49-60
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• 2021

본 연구는 덕성여자대학교 비교과프로그램 품질관리를 위한 인증평가제의 도입을 검토하는 데에 목적을 두어 실시되었다. 연구 방법은 문헌 분석과 전문가 회의와 같이 두 가지의 절차를 병행하여 구성되었다. 연구 내용은 덕성여자대학교에서 학생들의 학습역량 강화 지원을 위하여 다양하게 운영되고 있는 비교과프로그램의 품질관리를 보다 공식화된 수준과 체계화된 흐름에 따라 시행하기 위한 인증평가제의 도입 관련 수반조건이 구성되었다. 연구 결과, 「비교과인증평가에관한내규」는 비교과프로그램의 상시 모니터링과 연차 성과평가 간 연계적 흐름을 실제화하는 데 주요한 시행 기반이 될 뿐 아니라, 덕성여자대학교를 비롯한 비교과통합관리 지원체계를 구축하고 있는 각 대학별로 공통 사항에 해당된다는 측면을 분석할 수 있었다.

• The Korean Journal of Physiology and Pharmacology
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• 제15권6호
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• pp.423-429
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• 2011

B13 analogues are being considered as therapeutic agents for cancer cells, since B13 is a ceramide analogue and inhibits ceramidase to promote apoptosis in cancer cells. B13 sulfonamides are assumed to have biological activity similar to B13, since they are made by bioisosterically substituting the carboxyl moiety of B13 with sulfone group. Twenty B13 sulfonamides were evaluated for their in vitro cytotoxicities against human colon cancer HT-29 and lung cancer A549 cell lines using MTT assays. Replacement of the amide group with a sulfonamide group increased cytotoxicity in both cancer cell lines. The sulfonamides with long alkyl chains exhibited activities two to three times more potent than that of B13 and compound (15) had the most potent activity with $IC_{50}$ values of 27 and $28.7{\mu}M$ for HT-29 and A549, respectively. The comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were used to carry out QSAR molecular modeling of these compounds. The predictive CoMSIA models for HT-29 and A549 gave cross-validated q2 values of 0.703 and 0.830, respectively. From graphical analysis of these models, we suppose that the stereochemistry of 1,3-propandiol is not important for activity and that introduction of a sulfonamide group and long alkyl chains into B13 can increase cytotoxicity.

• Bulletin of the Korean Chemical Society
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• 제35권7호
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• pp.2065-2071
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• 2014

${\beta}$-Secretase (beta-amyloid converting enzyme 1 [BACE1]) is involved in the first and rate-limiting step of ${\beta}$-amyloid ($A{\beta}$) peptides production, which leads to the pathogenesis of Alzheimer's disease(AD). Therefore, inhibition of BACE1 activity has become an efficient approach for the treatment of AD. Ligand-based and docking-based 3D-quantitative structure-activity relationship (3D-QSAR) studies of acyl guanidine analogues were performed with comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) to obtain insights for designing novel potent BACE1 inhibitors. We obtained highly reliable and predictive CoMSIA models with a cross-validated $q^2$ value of 0.725 and a predictive coefficient $r{^2}_{pred}$ value of 0.956. CoMSIA contour maps showed the structural requirements for potent activity. 3D-QSAR analysis suggested that an acyl guanidine and an amide group in the $R_6$ substituent would be important moieties for potent activity. Moreover, the introduction of small hydrophobic groups in the phenyl ring and hydrogen bond donor groups in 3,5-dichlorophenyl ring could increase biological activity.

• 대한음성학회지:말소리
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• 제25_26호
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• pp.3-26
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• 1993

The goals of the present study were (3) to collect and analyze sets of fundamental frequency (F0) and formant frequency (F1, F2, F3) data of Korean diphthongs from ten linguistically homogeneous speakers of Korean males, and (2) to make a comparative study of Korean monophthongs and diphthongs. Various definitions, kinds, and previous studies of diphthongs were examined in the introduction. Procedures for screening subjects to form a linguistically homogeneous group, time point selection and formant determination were explained in the following section. The principal findings were as follows: 1. Much variation was observed in the ongliding part of diphthongs. 2. F2 values of (j) group descended while those of [w] group ascended, 3. The average duration of diphthongs were about 110 msec, and there was not much variation between speakers and diphthongs. 4. In a comparative study of monophthongs and diphthongs, Fl and F2 values of the same offgliding part at the third time point almost converged. 5. The gliding of diphthongs was very short beginning from the h-noise. Perceptual studies using speech synthesis are desirable to find major parameters for diphthongs. The results of the present study wi11 be useful in the area of automated speech recognition and computer synthesis of speech.