• 통합자연과학논문집
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• 제5권1호
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• pp.22-26
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• 2012

Chemokine receptor antagonists have potential applications in field of drug discovery. Although the chemokine receptors are G-protein-coupled receptors, their cognate ligands are small proteins (8 to 12 kDa), and so inhibiting the ligand/receptor interaction has been challenging. In particular, CCR2 and CCR5 and their ligands have been implicated in the pathophysiology of a number of diseases, including rheumatoid arthritis and multiple sclerosis. Based on their roles in disease, they have been attractive targets for the pharmaceutical industry, targeting both CCR2 and CCR5 could be a useful strategy. Because of the importance of these receptors, providing information regarding the binding site is of prime importance. Herein, we report the comparison of CCR2 of CCR5 binding sites both sequentially as well as structurally. We also urged the importance of crucial residues in the binding site, to facilitate the development of dual antagonists targeting both the receptors. These results could also be useful for the design of novel and potent dual CCR2 and CCR5 antagonists using structure based drug design.

• 무역학회지
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• 제47권3호
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• pp.177-190
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• 2022

This study is designed to identify the differences in the types and importance of trade claims at the national level. For analysis data, abstracts of arbitration and court judgments published on the website of the United Nations Commission on International Trade Law are collected and used. The target countries are China and the United States, with 102 cases from China and 59 cases from the United States. By applying topic modeling techniques to the collection decisions of China and the United States, trade claims are categorized, and the importance of each type is identified using the network centrality index derived through semantic network analysis. The analysis results are as follows. First, the main types of trade claims were the same for both the United States and China: product nonconformity, delivery issues, and payments. However, in China, the order of product nonconformity > delivery issues > payments was important, and in the United States, payments > product nonconformity > delivery issues were found to be important. This study is significant in that it presents a strategic trade claim management plan using a quantitative methodology.

• 정보기술과데이타베이스저널
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• 제4권1호
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• pp.129-138
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• 1997

In today's competitive environment, Information Technology is a resource of primary importance to most organizations. This paper compares Korea's IT maturity levels with respect to those of other major nations. For this research, we used an empirical approach, based on experts surveys. IT classification framework proposed by ETRI is adopted to organize the responses. The results of this study can be used for strategic IT planning by the government.

• 산업융합연구
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• 제14권2호
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• pp.25-31
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• 2016

As the importance of big data begins to be recognized, the government, local self-governing bodies, and corporations have taken interest in big data. However, unlike the past, there is various typical and atypical data, and some fields make use of big data planning and analytical technique, which is opening a way to capture new opportunities. The present study analyzes an improvement plan for bicycle roads by using the public data of Seoul and proposes its implications.

• Advances in concrete construction
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• 제15권2호
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• pp.137-147
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• 2023

Dynamic analysis of a shear deformable shell is investigated with accounting thickness stretching using Hamilton's principle. Through this method, the total transverse is composed into bending, shearing and stretching portions, in which the third part is responsible for deformation along the transverse direction. After computation of the strain, kinetic and external energies, the governing motion equations are derived using Hamilton's principle. A comparative study is presented before presentation of full numerical results for confirmation of the formulation and methodology. The results are presented with and without thickness stretching to show importance of the proposed theory in comparison with previous theories without thickness stretching.

• 한국치위생학회지
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• 제19권3호
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• pp.437-448
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• 2019

Objectives: The purpose of this study was to suggest an effective instruction method for dental hygiene students by determining the degree of importance and satisfaction that they attach to the courses. Methods: Data obtained from a survey that was conducted on 654 dental hygiene students were analyzed. Statistical Package for the Social Sciences version 23.0 was used for the statistical analysis. A paired t-test was conducted to detect the differences between the degree of importance that the respondents attached to the courses and the degree of satisfaction they achieved. A comparative analysis of the two was performed using the IPA analysis. Results: Regarding the items, the respondents found the environment most important, followed by the content, method, perspective, and assessment. Regarding satisfaction, they were most satisfied with the environment, followed by the perspective, method, content, and assessment. Regarding the importance of ideal teaching, the respondents gave the highest priority to 'a class in which the core content is summarized, emphasized, and explained.' The satisfaction was the highest toward 'PowerPoint-based classes in which the core content is well-organized.' Based on the results of the IPA analysis, the respondents regarded 16 items as requiring maintenance and continuous efforts, 12 items as low priority, and 4 items as requiring excessive efforts and timely improvement. Conclusions: An ideal class requires the instructor to utilize various teaching methods that would enable the students to comprehend the detailed teaching content and elicit active interaction and feedback from the students through easy-to-understand lectures that are appropriate for students.

• 한국융합학회논문지
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• 제13권3호
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• pp.23-31
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• 2022

본 연구는 H해운사에서 제공받은 Starcool사의 실제 냉동 컨테이너 운영데이터를 분석하였다. H사의 현장 전문가와 인터뷰를 통해 4가지 고장 알람 중 Critical 및 Fatal Alarm만 고장으로 정의하였고, 냉동 컨테이너 특성상 모든 변수를 사용하는 것은 비용측면에서 비효율을 초래하는 것을 확인하였다. 이에 본 연구는 특성 중요도 및 PCA 기법을 통한 냉동 컨테이너 고장 탐지 방법을 제시한다. 모델의 성능 향상을 위해 XGBoost, LGBoost 등과 같은 트리계열 모델을 통해 변수 중요도(Feature Importance)를 기반으로 변수 선택(Feature selcetion)을 하고 선택되지 않은 변수는 PCA를 사용하여 전체 변수의 차원을 축소시켜 각 모델별로 지도학습을 수행한다. 부스팅 기반의 XGBoost, LGBoost 기법은 본 연구에서 제안하는 모델의 결과가 62개의 모든 변수를 사용한 지도 학습의 결과보다 재현율(Recall)이 각각 0.36, 0.39씩 향상되는 되는 결과를 보였다.

• 정보관리학회지
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• 제39권2호
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• pp.325-346
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• 2022

뉴노멀 시대로 특징지어지는 현대사회가 COVID-19 팬데믹을 겪으면서 도서관에 많은 변화를 요구하였고, 도서관계는 이에 대하여 선제적으로 그리고 다각적으로 대응하였다. 본 연구는 팬데믹과 같은 새로운 환경이 사서들이 인식하는 도서관 운영정책 우선순위를 변화시킬 것이라고 보고, 2020년 팬데믹이 시작되는 시점과 2022년 팬데믹이 정점을 지난 시점에서 도서관 운영정책 중요도를 쌍대비교 분석을 통하여 파악하였고 그 차이를 비교·분석하였다. 1차 조사에서는 도서관경영, 도서관 서비스 관련 운영정책 영역을 중요하게 여겼다면, 2차 조사에서는 인적자원과 정보자원에 관련된 운영정책 영역을 보다 중요하게 인지하고 있었다. 또한, 전체 영역 상위 5위에 인적자원과 관련된 3개의 세부 운영영역과 자료구입 예산, 이용자만족도 기반의 정책이 포함되었다. 따라서 공공도서관은 새로운 패러다임에 빠르게 적응하면서도 지속가능한 도서관 서비스를 제공하기 위해서는 지속적인 인적자원에 대한 투자, 충분하고도 다양한 형태의 정보자원 구축, 그리고 이용자 맞춤 정책 수립 등을 우선적으로 수행해야 할 것이다.

• 한국보건간호학회지
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• 제37권1호
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• pp.25-40
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• 2023

Purpose: To compare perceptions of nurse-led health care visits in child daycare centers and calculate determination coefficients (DC) reflecting the job values. Methods: This was a secondary analysis study that applied the evaluation report for visiting nursing services for child daycare centers, prepared by the Seoul Nurses Association in 2021. Totally, 86 visiting nurses, 1997 childcare teachers, and 1915 parents were included in the study. The job recognition questionnaire was used to identify the levels of readiness, importance, and difficulty of a visiting nurse's job. Results: The visiting nurses showed high levels of readiness and importance for most duties and tasks expected of them. Compared to the nurses, the parents determined a greater importance towards the jobs of visiting nurses. The visiting nurses and childcare teachers exhibited similar levels of importance for the job. The highest and lowest DC scores were obtained for 'child developmental evaluation and referral' and 'child education', respectively. Conclusion: The duties and tasks verified in this study can be evidence for the job description, and should be preferentially developed for enhancing the competency of visiting nurses. Considering the importance of nurse-led health care, this will warrant an expansion of services to other regions.

• 유통과학연구
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• 제13권1호
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• pp.83-91
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• 2015

Purpose - Despite the structural irrationality of multi-level transportation and the oil price rise, the domestic freight transportation market continues to grow, mirroring the rise in e-commerce and resultant increase in courier services and freight volumes. Several studies on courier services have been conducted. However, few studies or statistics have been published regarding regular freight services although they have played a role in the freight service market. The present study identifies the characteristics of regular freight service users to seek competitiveness enhancement measures specific to regular freight services. Research design, data, and methodology - IPA is a comparative analysis of the relative importance of and satisfaction with each attribute simultaneously. This study used IPA because it facilitates the process of analyzing importance and performance, deriving implications and a visual understanding of results. To enhance the competitiveness of regular freight services, this study surveyed its current users regarding the importance of the regular freight service factors. A total of 200 copies of a questionnaire were circulated and 190 copies were returned. In addition to demographics, respondents answered questions about the importance of and satisfaction with services on a 5-point Likert scale. Excluding 3 inappropriate copies, 187 out of 190 copies were analyzed. PASW Statistics 18 was used for statistical analysis. A total of 20 question items were selected for the service factors presented in the questionnaire based on the 1st pilot survey and previous studies. Results - According to the IPA performed to compare the importance of and satisfaction with service factors, both importance and satisfaction are high in the 1st quadrant, which involves the economic advantage of using regular freight services, quick arrival at destinations, weight freight handling, and less time constraints on freight receipt/dispatch. This area requires continuous management. Satisfaction is higher than importance in the 2nd quadrant, which involves the adequacy of freight, cost savings over ordinary courier services, notification on freight arrival, and freight tracking information. This area requires intensive investment and management. Satisfaction is lower than importance in the 3rd quadrant, involving the credit card payment system, courier delivery service, distance to freight handling sites, easy access to freight handling sites, and prompt problem solving. This area requires further intensive management. Both importance and satisfaction are low in the 4th quadrant, involving the availability of collection service, storage space at freight handling sites, kindness of collection/delivery staff, kindness of outlet staff, and easy delivery checks. This area is a set of variables should be excluded from priority control targets. Conclusions - Based on the IPA, service factors that need priority controls because of high importance and low satisfaction include the credit card payment system, delivery service, distance to freight handling sites, easy access to freight handling sites, and prompt problem solving. The findings need to be applied to future marketing strategies for regular freight services and for developing competitiveness enhancement programs.