• Journal of Preventive Medicine and Public Health
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• v.33 no.1
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• pp.117-124
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• 2000

Objectives : It is the objective of this study to compare hepatotoxicity of nickel chloride and cadmium chloride with each other through IPRL(Isolated Perfused Rat Liver) method. Methods : Biochemical indicator of hepatic function such as AST(aspartate aminotransferase), ALT(alanine aminotransferase), LDH(lactate dehydrogenase) and perfusion flow rate were used as the indicator of hepatotoxicity. Oxygen consumption rate were used as vability indicator. $300({\pm}50)g$ - weighted rats were allocated randomly to each group($0{\mu}M,\;50{\mu}M,\;200{\mu}M\;NiCl_2\;and\;CdCl_2$ exposure) by 5, totally 25. After Krebs-Ringer bicarbonate butler solution flowed into the penal vein and passed the liver cell, it flowed out of vena cava. Liver was administered with each $NiCl_2\;and\;CdCl_2$ of each concentration and observed with buffer solution sampling time. Butler which got out of liver was sampled and then biochemical indicator of hepatotoxicity was measured. Results : AST, ALT, and LDH in buffer increased with sampling time much more in $CdCl_2$ exposure group than $NiCl_2$ exposure group in both 50 and $200{\mu}M$ and statistical significance w3s verified with 2-way repeated ANOVA. Viability was decreased more and more in all substances during passed time. Conclusions : It is inferred that $CdCl_2$ has stronger hepatotoxicity than $NiCl_2$. IPRL method would be used widely for acute hepatotoxicity when considerating the benefit of it.

• Research in Plant Disease
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• v.15 no.3
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• pp.165-169
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• 2009

Twelve Cucumber mosaic virus (CMV) isolates were isolated from genetically modified (GM) and non-GM Capsicum annuum in two GM fields, Namyangju and Anseong, and their properties were investigated in this study. Coat protein (CP) gene of the CMV isolates were synthesized by RT-PCR using genus-specific primers which designed to amplify a DNA fragment of 950 bp. Purified cDNA fragments were cloned into the pGEMT easy vector for sequence determination. Nucleotide sequences (internal 657 bp) of CMV isolates were compared with Fny-CMV CP sequences and there were no significant collection site specific sequence similarities found. When predicted amino acid sequences (219 amino acids) were compared with Fny-CMV CP amino acids sequences, there were 96.8% to 97.3% similarities found from Namyangju collections and 95.9% to 96.8% similarities from Anseong collections. The phylogenetic analysis with nucleotide sequences showed definite differences in CMVs which have been isolated from the two regions.

• Archives of Plastic Surgery
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• v.40 no.5
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• pp.530-535
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• 2013

Background Platelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400${\times}10^3$ cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process. However, even though PRP is widely used, the mechanism or actual effect is presently unclear. Therefore, this study was performed to investigate the levels of growth factors and platelet concentration rate. Methods Autologous blood for preparing PRP was obtained from healthy subjects aged 25 to 35 years. The samples were divided into 4 experimental groups (inactivated whole blood, inactivated PRP, activated whole blood with thrombin and calcium chloride, and activated PRP). The platelet counts in the blood were analyzed and the growth factors were quantitatively measured. A statistical analysis was performed by using Dunn's multiple comparison test. Results In the blood cell analysis, the platelet count of the PRP group was approximately 4.25 times higher than that of the whole blood group. In the quantitative analysis of growth factors, the platelet-derived growth factor (PDGF)-AB, PDGF-BB, and transforming growth factor-${\beta}$ of the inactivated and activated PRP groups were higher than those of the inactivated and activated whole blood groups (P<0.05). Conclusions In this study, the platelet count and the levels of PDGF-AB and PDGF-BB in the PRP were determined. Further, more research is required on the bioactivity level of the growth factors secreted during the process of PRP preparation and the potency of growth factors that can be exerted physiologically in vivo.

• Journal of Conservation Science
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• v.26 no.2
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• pp.149-156
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• 2010

One of resins, V-Flon is useful as a coating material because YK-D80, which is a solvent for V-Flon, is not highly volatile. However, it can not completely harden and can flow out when metal artifacts are joined and restored in the process of the treatment. Therefore, after the impregnation process in order to accelerate the hardening speed of a coating material, usually a dry oven was adopted. This study focused on finding the problems on the dry oven which is employed to increase the speed and investigating the most effective solvent and its composition by checking any change occurred depending on the concentration of solvents. Six different types of solvents were selected and samples were prepared in a manner that they were impregnated with solvents in three concentrations respectively (10%, 20%, 30%). To determine the condition of the samples, the stability evaluation was performed by measuring the change of color and the gloss, the thickness of coated layers, the corrosion after coating, the water resistance by contact angles. Through the comparative experiments between the natural drying and the artificial drying using a dry oven, it was found that when the dry oven is used, some problems are identified on the point of forming a uniform and stable layer because of the unstable data collected from the forced artificial dry. The experiments performed using 3 different concentration rates (10%, 20%, 30%) presented that in the case of 10% V-Flon in Xylene (using as a solvent), its layer was thin as well as it showed the high water-barrier property, which allows it to form the stably coated layer with the lower gloss and color change.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.11
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• pp.3418-3426
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• 2009

The purpose of this study was to investigate the feasibility of field operation protocol for cardiopulmonary resuscitation(CPR) in person with non-traumatic arrest. This study was performed from May 1 through June 27, 2008, and subjects were 150 students who are attending the department of Emergency Medical Service in J and K universities which located in Jeollabuk-do and Jeollanam-do areas. Practical conformance was verified using by nonequivalent control group pretest-posttest design. This study divided into two groups; experimental group that employed field operation protocol and control group that applied conventional CPR protocol, and comparative analyzed statistically the necessary time of the items of each protocol. The results indicated that each performance time of 18 items was reduced over 3 seconds except 5 items(assessment of consciousness, airway control, two times of artificial respiration, check of circulation, and five cycles of CPR). And time of 6 items(intubation, peripheral intravenous line, reassessment of consciousness, pupil reaction, carotid artery pulse, and vital sign) was minimized more than 60 seconds, and total performing time was shortened 110.85 seconds. The results suggested that total performing time in pre and post test where the protocol was applied for two groups showed a statistically significant decrease(t=-6.580, p=.000). Consequently, field operation protocol for cardiopulmonary resuscitation(CPR) in person with non-traumatic arrest will be a available manual which support prompt and accurate decision making, and improve emergency medical service.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.5
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• pp.150-159
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• 2011

The need of securing the stability and extending service lives by efficient maintenance of deteriorated tunnels for several decades has been increased. The stability and the usability of conventional tunnels can be decreased by change of physical properties of the surrounding ground, geometrical properties of the tunnel, an underground water level, environmental conditions, oxidation of lining and the breakdown of constituent materials. In respect of a long-term view, it is need to check all sorts of degradation, the degree of damage and durability to improve the serviceability and to come up with measures to maintain effectively. This paper is about study to analyze the stability of conventional tunnels(American Steel Support Method. ASSM). Three tunnels are chosen in those built in the 1930s and 1960s and the locations of tunnels are selected variously(ChungCheong, GyungBuk, GangWon, Jeolla, etc.) to secure reliability of this study. The state of repair and reinforcement of linings, cracks, and thickness and strength of lining of conventional tunnels in service are researched, compared and analyzed. The crack gauge, the GPR, the schmitt hammer was used for the crack investigation, cavitation, the strength respectively. By using these, the comparative analysis for conventional tunnels was conducted. As a result, there are more cracks in tunnels built in the 1930s than those of tunnels built in the 1960s, and lining strength of the 1930s is higher than those of the 1960s. The thickness of lining in tunnels built in the 1960s is higher than those in tunnels built in the 1930s. In proportion to thickness, cavitation occurred more frequently in tunnels built in the 1960s compared to those in tunnels built in the 1930s.

• Journal of the korean academy of Pediatric Dentistry
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• v.32 no.2
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• pp.262-269
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• 2005

The purpose of this study was to compare the efficacy and complications of two oral sedative regimens, chloral hydrate (60mg/kg)/hydroxyzine(25mg) versus midazolam(1mg/kg)/meperidine(1mg/kg) for the sedation of pediatric dental patients. Fifteen patients(mean age 36.2months, range 24-47months), ASA Class I or II, who needed at least two restorative dental procedures were selected in this double-blind, randomized study. All subjects were randomly assigned to receive either chloral hydrate/hydroxyzine or midazolam/meperidine and 50% $N_2O/O_2$ was administered at each appointment. Behavior assessment(sleep, movement, crying, overall behavior) was made using Houpt Sedation Rating Scale and physiologic parameters(pulse rate, oxygen saturation) were monitored using pulse oximeter. The incidence of hypoxia($SpO_2$ 90% or less, at least 10s duration) and vomiting was recorded. Patients sedated with chloral hydrate/hydroxyzine showed significantly better overall behavior score than patients sedated with midazolam/meperidine. There was no clinically significant difference in the incidence of hypoxia and vomiting. It was concluded that oral administration of chloral hydrate/hydroxyzine is more effective than midazolam/meperidine for the sedation of pediatric dental patients.

• Journal of Environmental Policy
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• v.5 no.3
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• pp.25-56
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• 2006

We reviewed and compared nationwide surveys conducted in advanced countries (i.e., Japan, Germany, USA, and UK) with those in Korea, including the third Nationwide Survey of Natural Environments, which began in 2006 and will proceed until 2010. Based on this comparative analysis, we suggest alternatives to the nationwide survey of natural environments that are suited to Korea. Given the focus on species abundances and distributions in previous nationwide surveys in Korea, surveys of habitats, ecosystems, and ecoregions are required to more effectively protect biological resources in Korea. Furthermore, their spatial distributions should be mapped using periodical satellite images and aerial photographs. In particular, satellite images can be used to survey species, habitats, and ecosystems. Natural resources monitoring and management specialists are needed to collect various data and improve survey results. The participation of community volunteers is also important to develop an awareness in local residents of natural environment conservation. Independent survey institute (i.e., a 'National Ecosystem Institute') should be established to develop a database and survey scheme for species, habitats, and ecosystems throughout Korea. Moreover, the survey institute could develop natural environmental policy through the data analysis to meet the objectives of the Convention on Biological Diversity. The establishment of a survey institute will allow the completion of a natural environment survey that considers various factors, including physical habitat conditions. This will allow us to detect subtle changes in species abundance and spatial distributions and provide accurate and timely information on natural environments.

• Management & Information Systems Review
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• v.34 no.3
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• pp.161-177
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• 2015

Currently, the influence of the Internet portal sites that can make it quick and easy to contact the vast amount of information is increasing. Users can connect the Internet through a portal to obtain information, such as communication between Internet users, which can be used to meet a variety of purposes. People are exposed to a variety of information from other users in the search for a movie and get information. The impact on the reviews and ratings with the limited number of characters of the film allows users to form a relationship to the movie, decide whether you want to see the movie or find another movie. but, the user can not read the whole movie review. When user see the overall evaluation, the user can receive the correct information. This research conducted a study on the prediction of the rating by the use of review data. Information of reviews, is divided into two main areas: the"fact" and "opinion". "Fact" is to convey the dispassionate information and "Opinion" is, to represent the user's feelings. In this study, we built sentiment dictionary based on the assessment and evaluation of the online review and applied to evaluate other movies. In the comparative study with a simple emotion evaluation technique, we found the suggested algorithm got the more accurate results.

• Journal of Korean Society for Geospatial Information Science
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• v.16 no.3
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• pp.35-41
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• 2008

Recently needs for the convergence of CAD and GIS data are increasing, and many studies on converting two systems to each other are being carried out. In this study, to revise and update the building data of digital map using CAD data for construction, the outline of building is abstracted from the CAD data and the outline is generalized to the same level of detail with the building data of digital map. Several line simplification algorithms to generalize the outline are adopted and compared, especially at the view of satisfaction to the drawing rule for digital map. Douglas-Peucker algorithm, Lang's algorithm, Reumann-Witkam algorithm, and Opheim algorithm are applied as the line simplification method. To evaluate the results of these algorithms, visual assessment and variation ratio of the number of points, total length of lines, the area of polygon, and satisfaction ratio to the drawing rule of digital map are analyzed. The result of Lang algorithm and Douglas-Peucker algorithm show superior satisfaction ratio. But general satisfaction ratio is 50~60% for all algorithm. Therefore there seems to be a limit to use these algorithms for the simplification method to update the building data in digital map and it is necessary to develop line simplification algorithm which satisfy the drawing rule well.