• Journal of Yeungnam Medical Science
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• v.37 no.4
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• pp.329-331
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• 2020

Negative myoclonus (NM) is a shock-like jerky involuntary movement caused by a sudden, brief interruption of tonic muscle contraction. NM is observed in patients diagnosed with epilepsy, metabolic encephalopathy, and drug toxicity and in patients with brain lesions. A 55-year-old man presented with NM in both his arms and neck. He has taken medications containing tramadol at a dose of 80-140 mg/day for 5 days due to common cold. He had no history of seizures. Acute lesions were not observed during magnetic resonance imaging, and abnormal findings in his laboratory tests were not noted. His NM resolved completely after the discontinuation of tramadol and the oral administration of clonazepam. Our case report suggests that tramadol can cause NM in patients without seizure history or metabolic disorders, even within its therapeutic dose.

• The Journal of Pediatrics of Korean Medicine
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• v.28 no.1
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• pp.61-70
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• 2014

Objectives The purpose of this study is to report three cases of epileptic children who were treated by oriental medicine. Methods Three epileptic children were treated by Gwakhyangjeonggi-san and Kuibiondam-tang. Two children had took combination therapy; anti-epilepsy drugs and oriental medicines and the other one took only oriental medicines. We measured frequency and intensity of seizure, and observed general conditions. Results The oriental medicine treatment is not only reducing seizures, but also improving general condition like digestion, constipation and reducing frequency of common cold and symptom of rhinitis. Conclusions Epilepsy in childhood is induced by various factor like Fung (風), Dam (痰), Sik (食), Kyung (驚). We administrated oriental medicine and prevented seizures.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2002.05b
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• pp.468-471
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• 2002

The present study was undertaken to Investigate the effects of low temperature and salicylic acid (SA) on chilling tolerance In acclimated and nonacclimated cucumber seedlings. Acclimation significantly affected survival and shoot dry weights. Injuries of acclimated seedlings at the third leaf stage were on the average smaller by half than those of the nonacclimated ones. Chilling caused a large increase in free proline levels, regardless of acclimation status. Exogenous treatment with SA resulted in improvement in growth and survival of acclimated, chilled seedlings, indicating SA and acclimation have common effects. Cycloheximide treatment In the presence of SA restored acclimation-induced chilling tolerance. An elevated proline level was observed in cold-treated and SA- treated plants and the level was more pronounced in the light than in the dark at chilled temperature, indicating that endogenous proline may play a role in chilling tolerance.

• Korean Journal of Pharmacognosy
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• v.41 no.2
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• pp.94-96
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• 2010

Crude drug 'InDong(忍冬)' has been used mainly to cure common cold, high fever and gonorrhea. With regard to the botanical origin of InDong, it has been considered to be Lonicera species of Caprifoliaceae, but there was no pharmacognostical conformation on it. To clarify the botanical origin of 'InDong', the anatomical characteristics of the branches of Lonicera species growing wild in Korea, Lonicera japonica and L. japonica forma. chinensis were studied. As a result, it was clarified that InDong was the branches of Lonicera japonica.

• Korean Journal of Pharmacognosy
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• v.41 no.1
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• pp.1-5
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• 2010

Korean folk medicine 'DulGugWha' has been used to cure common cold, cough and chronic and acute gastiritis in Korea. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'DulGugWha', the morphological and anatomical characteristics of Chrysanthemum species growing in Korea, i.e. C. boreale, C. indicum, C. zawadskii and C. zawadskii var. latilobum were studied. As a result, 'DulGugWha' was proved to be the whole plant body of Chrysanthemum boreale of Compositae.

• The Journal of Pediatrics of Korean Medicine
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• v.12 no.1
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• pp.41-53
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• 1998

The purpose of this study was on effect of Gagamsipungtang(GGSP) which removal of fever, side effect etc. During 4months between September and December 1998 , GGSP water extract administered to the patients coming to Dept. of Pediatrics, Dongguk university Pundang Oriental Hospital on account of the symptom of fever with common cold in acute stage, and this study was conducted for 97 children (male 55, female 42). GGSP was used in children both men and women. There were 13 kinds of complications including cough, nasal obstruction, headache, nausea, anorexia, chilling and sweat etc. The distributions of remedial value were improved(62.9%) and no improved(37.6%) patients. 'Improved' standed for no fever over 2 days after GGSP used to patients. GGSP was affected in remedial values by only used without antipyretics. Side effect were diarrhea, anorexia, vomiting and so on.

• Natural Product Sciences
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• v.10 no.5
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• pp.217-219
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• 2004

Cissus quadrangularis L. variant I (Family: Vitaceae), the common variant with square stem is widely used for peptic ulcer disorders (PUD) in traditional medicine. Aerial parts were collected during flowering and vegetative seasons and analysed. Aqueous (hot and cold) and solvent extracts (acetone, chloroform and ethanol) were screened for their anti-Helicobacter pylori (Hp) activities. Among them chloroform extract was observed to recover bioactive principles markedly with low minimal inhibitory concentration (MIC) and minimal lethal concentration (MLC). MIC was $30\;{\mu}g$ in both samples and MLC was $35\;{\mu}g$ for vegetative and $30\;{\mu}g$ for flowering seasons, respectively. Extracts from samples collected during flowering season were better than thse of vegetative season.

• Korean Journal of Pharmacognosy
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• v.18 no.3
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• pp.191-195
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• 1987

Korean folk medicine 'Sin Seong Cho' (神聖草)has been used to cure common cold, neuralgia and cancer of the stomach in Korea. The botanical origin of the crude drug has been no pharmacognostical confirmation on it. To clarify the botanical origin of 'Sin Seong Cho', the morphological and anatomical characteristics of the rhizomes of Davallia mariesii Moore and Neocheiropteris ensata (Thunb.) Ching growing in Korea were examined. As the result, it was made clear that 'Sin Seong Cho' from Korea was derived from the rhizomes of Davallia mariesii, rarely from the rhizomes of Neocheiropteris ensata.

• Natural Product Sciences
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• v.17 no.4
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• pp.303-308
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• 2011

Spirodela polyrrhiza L. Schleid. (Lemnaceae), also known as 'duckweed', is a traditional medicine in Korea. The whole plant is used to treat many diseases, including the common cold, edema, acute nephritis, and urticaria. The present study investigated antinociceptive properties of the EtOAc soluble fraction of S. polyrrhiza (ESP). The antinociceptive activities of ESP were studied using experimental models of pain, including thermal nociception methods, such as the tail immersion test and the hotplate test. Moreover, we studied chemical nociception induced by intraperitoneal acetic acid and subplantar formalin in mice. ESP exhibited dose-dependent antinociceptive activity in both thermal and chemical pain models. In a drug combination test using the opioid receptor antagonist naloxone, diminished analgesic activities of ESP were observed, indicating that the antinociceptive activity of ESP is mediated by opioid receptors.

• The Korean Journal of Pain
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• v.26 no.3
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• pp.295-298
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• 2013

Glomus tumors are benign tumors that account for 1% to 5% of all soft tissue tumors of the hand and are characterized by a triad of sensitivity to cold, localized tenderness and severe paroxysmal pain. Paroxysmal pain is a symptom common not only in glomus tumors but also in CRPS, and the hand is one of the commonly affected sites in patients with both glomus tumors and CRPS. Therefore, it is not easy to clinically diagnose glomus tumors superimposed on already affected region of CRPS patients. We report a case of glomus tumor concomitantly originating with CRPS at the hand.