• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2003.11a
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• pp.168-172
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• 2003

This paper analyzes the output noise and the noise figure of common source MOSFET pair each input of which is separately driven in the different frequencies. This analysis is performed for concurrent dual band cascode CMOS LNA with double inputs and single output fabricated in $0.18{\mu}m$ CMOS process. Since both inputs and output are matched to near $50{\Omega}$ using on-chip inductors, the measured noise figures are much higher than those of usual CMOS LNA. But, the main concern of this paper is focused on the added noise features due to the other channel common source stage. The dual-band LNA results in noise figure of 4.54dB at 2.14GHz and 6.03dB at 5.25GHz for selectable operation and 7.44dB and 6.58dB for concurrent operation. The noise analysis explains why the added noise at each band shows so large difference.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.4
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• pp.1337-1341
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• 2015

Background: Breast cancer is the most common cancer and the second principal cause of cancer deaths among women worldwide, including Malaysia. This study focused on media choice and attempted to determine the communication channels mostly used and preferred by women in seeking information and knowledge about breast cancer. Materials and Methods: A cross sectional study was carried out to examine the breast cancer prevention information seeking behavior among 450 students at one private university in Malaysia. Results: The mean age of respondents was $25{\pm}4.3years$. Common interpersonal information sources were doctors, friends, and nurses and common channel information sources were television, brochure, and internet. Overall, 89.9% used cell phones, 46.1% had an interest in receiving cell phone breast cancer prevention messages, 73.9% used text messaging, and 36.7% had an interest in receiving text breast cancer prevention messages. Bivariate analysis revealed significant differences among age, eduation, nationality and use of cell phones. Conclusions: Assessment of health information seeking behavior is important for community health educators to target populations for program development.

• The Korean Journal of Community Living Science
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• v.25 no.1
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• pp.51-64
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• 2014

With a shift in the rural development process toward a bottom-up approach, the need to enhance the endogenous capacity of communities has become the core of rural development. In this regard, scholars have paid close attention to social capital to identify ways to facilitate endogenous rural development but focused mainly on relationships between social capital and local environment. That is, few studies have investigated the relationships between social capital and its various dimensions in the context of rural development initiatives. This study examines the effects of social capital on the problem-solving ability of community residents'rural development initiatives and assesses the types of social capital associated with such initiatives to propose optimal path for improving this ability. To distinguish between major dimensions of social capital, a questionnaire was developed by considering various stages of the rural development process. The survey considered a sample of 59 employees from public rural development institutions. According to the results, four paths were significant at the 5% level. Among these four paths, three set common goals. The effective channel was the path [common goals${\Rightarrow}$network${\Rightarrow}$cooperation${\Rightarrow}$problem-solving ability]. The key factor in improving problem-solving skills, the endogenous ability of community residents to facilitate rural development initiatives. The results suggest that governments should strengthen education and training programs to help residents set their common goals.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.2
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• pp.140-144
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• 2004

The selectable dual band LNA usually uses common source transistor pair each input of which is selectively driven at a different frequency in a series resonant form. This paper analyzes the degradation in noise figures of the MOSFET common source pair with series resonance when it is driven concurrently at both inputs with different frequencies as a concurrent dual band LNA. Results of analysis will be compared with the measured noise figures of CMOS LNA with double inputs fabricated in 0.18 $\mu\textrm{m}$ CMOS process. Additionally, analyzing the contributions of FET channel noise and source noise from the LNA operating in the other band, this paper proposes optimum matching topology which minimizes the added noises for concurrent operation.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.12
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• pp.40-48
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• 2013

This paper presents multi-channel transimpedance amplifier(TIA) arrays in short-range LADAR systems for unmanned vehicles, by using a 0.18um CMOS technology. Two $4{\times}4$ channel TIA arrays including a voltage-mode INV-TIA and a current-mode CG-TIA are introduced. First, the INV-TIA consists of a inverter stage with a feedback resistor and a CML output buffer with virtual ground so as to achieve low noise, low power, easy current control for gain and impedance. Second, the CG-TIA utilizes a bias from on-chip bandgap reference and exploits a source-follower for high-frequency peaking, yielding 1.26 times smaller chip area per channel than INV-TIA. Post-layout simulations demonstrate that the INV-TIA achieves 57.5-dB${\Omega}$ transimpedance gain, 340-MHz bandwidth, 3.7-pA/sqrt(Hz) average noise current spectral density, and 2.84mW power dissipation, whereas the CG-TIA obtains 54.5-dB${\Omega}$ transimpedance gain, 360-MHz bandwidth, 9.17-pA/sqrt(Hz) average noise current spectral density, and 4.24mW power dissipation. Yet, the pulse simulations reveal that the CG-TIA array shows better output pulses in the range of 200-500-Mb/s operations.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.12
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• pp.1380-1387
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• 2012

The transmit/receive(T/R) module is a key component in the active phased array system. The brick-type T/R module has been widely used and the miniaturization has been an important factor to get the flexibility of the system configuration. For the miniaturization, multi-function chips(MFC) having a common leg configuration are suitable to reduce the number of required MMICs and a high isolation between transmit and receive paths is necessary for the high gain T/R modules. In this work, we propose a bias timing scheme for the compact T/R module and show the optimum timing based on measurements, in order to improve the feed-back path loop problem and the consequent isolation problem of the common leg configuration. We have implemented high power(7 W/channel) and high T/R gain(35 dB transmit and 30 dB receive gains) within the half size($140{\times}80{\times}16mm^3$) of the conventional T/R modules.

• Journal of Pharmacopuncture
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• v.16 no.3
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• pp.39-45
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• 2013

Objectives: Buxus Microphylla var. Koreana Nakai Extract (BMKNE) is used as a folk remedy for malaria and veneral disease. In the present study, we investigated the effects of BMKNE in the growth and the survival of AGS cells, the most common human gastric adenocarcinoma cell lines. Methods: The AGS cells were treated with varying concentrations of BMKNE. Analyses of the sub G1 peak, the caspase-3 and -9 activities, and the mitochondrial depolarization were conducted to determine whether AGS cell death occured by apoptosis. Also, to identify the role of transient receptor potential melastatin (TRPM) 7 channels in AGS cell growth and survival, we used human embryonic kidney (HEK) 293 cells overexpressed with TRPM7 channels. Results: Experimental results showed that the sub G1 peak, the caspase-3 and -9 activities, and the mitochondrial depolarization were increased. Therefore, BMKNE was found to induce the apoptosis of these cells, and this apoptosis was inhibited by SB203580 (a p38 mitogen-activated protein kinase (MAPK) inhibitor), and by a c-jun NH2-terminal kinase (JNK) II inhibitor. Furthermore, BMKNE inhibited TRPM7 currents and TRPM7 channel over-expressions in HEK 293 cells, exacerbating BMKNE-induced cell death. Conclusions: These findings indicate that BMKNE inhibits the growth and the survival of gastric cancer cells due to a blockade of the TRPM7 channel's activity and MAPK signaling. Therefore, BMKNE is a potential drug for treatment of gastric cancer, and both the TRPM7 channel and MAPK signaling may play an important role in survival in gastric cancer cells.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.23 no.10
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• pp.7-13
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• 2009

By incorporating a polarization beam splitter and fiber coupler, we propose a fiber-optic multiwavelength-switchable interleaving filter that can function as a polarizaiton-independent transmission or reflection-type one. The proposed filter consists of a polarizaiton beam splitter and a Sagnac birefringence loop that is composed of a 50:50 coupler, polarizaiton-maintaining fibers, and two quarter-wave plates. In the proposed filter, a transmission-type filter with a channel isolation > 18[dB] or a reflection-type one with a channel isolation ~3[dB], whose channel spacing and switching displacement were 0.8 and 0.4[nm] in common, respectively, could be obtained. Channel interleaving operation could be performed by the proper control of waveplates within the Sagnac birefringence loop.

• Journal of Institute of Control, Robotics and Systems
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• v.22 no.3
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• pp.199-203
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• 2016

A brain-computer interface or BCI provides an alternative method for acting on the world. Brain signals can be recorded from the electrical activity along the scalp using an electrode cap. By analyzing the EEG, it is possible to determine whether a person is thinking about his/her hand or foot movement and this information can be transferred to a machine and then translated into commands. However, we do not know which information relates to motor imagery and which channel is good for extracting features. A general approach is to use all electronic channels to analyze the EEG signals, but this causes many problems, such as overfitting and problems removing noisy and artificial signals. To overcome these problems, in this paper we used a new optimization method called the Fruit Fly optimization algorithm (FOA) to select the best channels and then combine them with CSP method to extract features to improve the classification accuracy by linear discriminant analysis. We also used particle swarm optimization (PSO) and a genetic algorithm (GA) to select the optimal EEG channel and compared the performance with that of the FOA algorithm. The results show that for some subjects, the FOA algorithm is a better method for selecting the optimal EEG channel in a short time.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.5
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• pp.305-310
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• 2010

The human $ether$-$a$-$go$-$go$-related gene ($hERG$) channel is important for repolarization in human myocardium and is a common target for drugs that prolong the QT interval. We studied the effects of two antipsychotics, tiapride and sulpiride, on hERG channels expressed in $Xenopus$ oocytes and also on delayed rectifier $K^+$ currents in guinea pig cardiomyocytes. Neither the amplitude of the hERG outward currents measured at the end of the voltage pulse, nor the amplitude of hERG tail currents, showed any concentration-dependent changes with either tiapride or sulpiride ($3{\sim}300{\mu}M$). However, our findings did show that tiapride increased the potential for half-maximal activation ($V_{1/2}$) of HERG at $10{\sim}300{\mu}M$, whereas sulpiride increased the maximum conductance ($G_{max}$) at 3, 10 and $100{\mu}M$. In guinea pig ventricular myocytes, bath applications of 100 and $500{\mu}M$ tiapride at $36^{\circ}C$ blocked rapidly activating delayed rectifier $K^+$ current ($I_{Kr}$) by 40.3% and 70.0%, respectively. Also, sulpiride at 100 and $500{\mu}M$ blocked $I_{Kr}$ by 38.9% and 76.5%, respectively. However, neither tiapride nor sulpiride significantly affected the slowly activating delayed rectifier $K^+$ current ($I_{Ks}$) at the same concentrations. Our findings suggest that the concentrations of the antipsychotics required to evoke a 50% inhibition of IKr are well above the reported therapeutic plasma concentrations of free and total compound.