• Journal of Acupuncture Research
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• 제32권3호
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• pp.147-161
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• 2015

Objectives : The purpose of this study was to review the effectiveness of acupuncture and moxibustion therapy for the treatment of acute herpes zoster. Methods : Data was collected by two researchers. Clinical trials on PubMed were retrieved using MeSH terms including "herpes zoster" combined with "acupuncture therapy", "moxibustion", "bloodletting", "electroacupuncture", and related keywords. We excluded irrelevant studies and included randomized and non-randomized controlled trials, case series and case reports. Finally, we selected a total of thirteen studies and conducted a literature analysis and an object quality assessment. Results : Twelve of thirteen studies were about acupuncture and moxibustion combined therapy. Only one study suggested that a single acupuncture therapy is expected to be equally as effective as a common western medicine therapy. There was some evidence related to the effectiveness of moxibustion, venesection and electroacupuncture, but it dealt with combining therapy and was insufficient, and with an inclusion of potential risk factors. Only one study was conducted under approval from an institutional review board. No severe treatment-related adverse events were observed. A quality assessment suggested that there was some weakness in the areas of blinding and concealment. Conclusions : There is some evidence that suggests the effectiveness and safety of acupuncture and moxibustion combined therapy as a treatment for acute herpes zoster.

• PNF and Movement
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• 제18권1호
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• pp.23-34
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• 2020

Purpose: To explore the effects of action observation combined with modified constraint-induced movement therapy on upper-extremity function and the activities of daily living in subacute stroke patients. Methods: Twenty-four subacute stroke patients were randomly assigned to the experimental group or the control group (n = 12 each). Both groups received therapy based on motor learning concepts, including repetitive and task-specific practice. The experimental group watched video clips for 10 minutes related to tasks performed during modified constraint-induced movement therapy while the control group watched videos unrelated to upper-extremity movement. These programs were performed for 40 minutes a day five times a week for four weeks. Their scores on the Fugl-Meyer assessment of upper extremities (FMA-UE), the action research arm test (ARAT), a motor activity log (amount of use [AOU] and quality of movement [QOM]), and the modified Barthel index (MBI) were recorded. Results: In both groups, all variables were significantly different between the pre-test and post-test periods (p < 0.05). The post-test variables were significantly different within each group (p < 0.05). In the experimental group, the changes between pre-test and post-test scores in the FMA-UE (14.39 ± 4.31 versus 6.31 ± 4.63), the ARAT (16.00 ± 4.73 versus 11.46 ± 3.73), MAL-AOU (1.57 ± 0.15 versus 1.18 ± 0.28), and MBI (27.54 ± 4.65 versus 18.08 ± 8.52) were significantly higher than those of the control group (p < 0.05). Conclusion: These findings suggest that action observation combined with modified constraint-induced movement therapy may be a beneficial rehabilitation option to improve upper-extremity function in subacute stroke patients with moderate impairment.

• 대한핵의학회지
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• 제14권2호
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• pp.35-40
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• 1980

In order to compare the therapeutic effect as well as side effects between antithyroid therapy and radioiodine therapy in hyperthyroidism, the author evaluated 111 cases of hyperthyroidism which were composed of 57 patients with antithyroid treatment, 23 patients with combined treatment comprising of antithyroid and radioactive iodine ($^{131}I$) and 31 patients with treatment of $^{131}I$ alone. The $^{131}I$ treatment was limited to older age, above 20 years of age, and not employed in patients with pregnancy and lactation. The patients treated with antithyroid belonged to relatively younger age, and also milder in symptoms and thyroid function tests. The remission rate of antithyroid therapy group was 97.8% within 16 months. Among them the early remission rate occured within 4 months was found to be 21.7%. The combined therapy group, having prescribed more severe cases, showed the remission rate to be 75% within 16 months. The remission rate of $^{131}I$ therapy group revealed 90.9% within 16 months. Among them the early remission rate taking place within 4 months disclosed 16.7%. The side effects of antithyroid drug, propylthiouracil, were noted as follows: itching (2.7%) skin rashes (1.3%), and adverse enlargement of goiter (10.7%). The side effects $^{131}I$ therapy were transient hypothyroidism(3.9%) permanent hypothyroidism (7.8%) and itching (2.0%).

• 척추신경추나의학회지
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• 제13권1호
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• pp.1-10
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• 2018

Objectives: To evaluate the evidence supporting the effectiveness of Chuna manual therapy for rheumatoid arthritis. Methods: We conducted a search across 9 electronic databases to find all randomized controlled clinical trials (RCTs) that used Chuna manual therapy as a treatment for rheumatoid arthritis. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. Results: Our inclusion criteria were met by 5 RCTs. The meta-analysis showed positive results for the use of Chuna manual therapy combined with oriental usual care (UC) in terms of the efficacy rate, pain, and duration of morning stiffness when compared to western UC. Positive results were also obtained in terms of the efficacy rate, when Chuna manual therapy combined with medication was compared to medication treatments alone. Conclusions: Our systematic review found encouraging, but limited evidence of Chuna manual therapy for rheumatoid arthritis. However, to obtain stronger evidence without the drawbacks of trial design and the quality of studies, we recommend a comparative research to test the effectiveness of Chuna manual therapy.

• 대한물리치료과학회지
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• 제26권3호
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• pp.57-69
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• 2019

Background: The purpose of this study was to compare and analyze the effects of neck and trunk combined exercise program and single exercise on neck angle and neck and shoulder muscle activity. Design: Randomized controlled trial. Methods: In the single exercise group, the basic stretching, head bending and neck bending exercises were performed. The neck and trunk combined exercise group performed torso strength and trunk stability exercises to stabilize the trunk, and then performed the same neck exercise as the single exercise group. The exercise program was conducted 5 days per week for 2 weeks. One-way repeated ANOVA was used to investigate the statistical analysis of neck angle, neck and upper and middle trapezius muscle activity. Results: 1) There was no significant difference in neck angle degree after exercise in neck single exercise group. 2) In the neck and trunk combined exercise, the neck angle degree decreased continuously with the increase of the experimental period and showed a significant difference. 3) In the single exercise group, the muscles which showed significant difference compared to the post-exercise were the right upper, left and right middle trapezius. 4) In the neck and trunk combined exercise group, the right neck muscles showed significant difference after the exercise before the experiment. Conclusion: It was found that the neck and trunk combined exercise was more effective in reducing neck angle and the muscle activity of the subjects with forward head posture was decreased and increased. However, both exercises showed positive effects.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2681-2684
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• 2014

Aim: To compare drainage alone or combined with anti-tumor therapy for treatment of obstructive jaundice caused by recurrence and metastasis after primary tumor resection. Materials and Methods: We collect 42 patients with obstructive jaundice caused by recurrence and metastasis after tumor resection from January 2008 - August 2012, for which percutaneous transhepatic catheter drainage (pTCD)/percutaneous transhepatic biliary stenting (pTBS) were performed. In 25 patients drainage was combined with anti-tumor treatment, antineoplastic therapy including intra/postprodure local treatment and postoperative systemic chemotherapy, the other 17 undergoing drainage only. We assessed the two kinds of treatment with regard to patient prognosis. Results: Both treatments demonstrated good effects in reducing bilirubin levels in the short term and promoting liver function. The time to reobstruction was 125 days in the combined group and 89 days in the drainage only group; the mean survival times were 185 and 128 days, the differences being significant. Conclusions: Interventional drainage in the treatment of the obstructive jaundice caused by recurrence and metastasis after tumor resection can decrease bilirubin level quickly in a short term and promote the liver function recovery. Combined treatment prolongs the survival time and period before reobstruction as compared to drainage only.

• 대한물리의학회지
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• 제19권1호
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• pp.119-129
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• 2024

PURPOSE: The purpose of this study was to examine the effectiveness of a low-intensity combined exercise program on daily physical fitness parameters such as balance, flexibility, muscle strength, and fear of falling of elderly women in the community. METHODS: This study assigned 30 elderly women randomly into two groups: The control and experimental groups. The control group (n = 15) underwent routine gait. The experimental group (n = 15) underwent the low-intensity combined exercise. The exercise program in this study comprising combined exercise, including balance, flexibility, muscle strength training, and the exercise program using props was conducted twice a week for 8 weeks. RESULTS: The average age of the control and experimental groups was 77.27 years and 78.33 years, respectively. There were significant differences in static balance (t = -4.167, p < .001), dynamic balance (t = 2.463, p < .001), (t = -3.870, p < .001), (t = -2.262, p < .001), (t = -5.732, p < .001), (t = -6.573, p < .001), and fear of falling (t = -5.129, p < .001). CONCLUSION: The results show that low-intensity combined exercise is an effective intervention that improves physical health fear of falling in older women. The combined exercise program was found to be more effective in terms of physical function and fall-related psychological function compared to the control group that only walked.

• Radiation Oncology Journal
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• 제7권1호
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• pp.1-13
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• 1989

Effects of ionizing radiation alone and combined with chemotherapy on tumor growth and it's clonal specificity monitored by changes in distribution of chromosome number were studies in A549 ceil line originated from human adenocarcinoma of the lung. Radiation (300 rad, 600 rad and 900 rad) were delivered with or without 5-FU. Forty eight hours later, 57.5% of growth inhibition of cell w8s seen in cells treated with 5-FU concentration of $0.4{\mu}g/ml$ for 24hr exposure. Cell survival curves after radiation with and without 5-FU were made. Chromosomal analysis of cells in metaphase in control, and in cells treated with 300 rad of radiation, or $0.4{\mu}g/ml$ of 5-FU treatment, and combined treatment of both were done to examine the changes in ploidy and number of chromosome. Radiation combined with S-FU enhanced growth inhibition of A549 cells. However, no evidence of synergegic effects in growth. inhibition was observed in the cells treated with the combination therapy. Pattern of chromosomal distribution of survived cells were shifted from hyperploidy to hypoploidy by single dose of radiation (300 rad). As radiation dose increased a large number of hypoploidy cells were observed. Following treatment of cells with 5-FU, chomosomal distribution of survived cells were also shifted to hypodiploidy which were seen in cells treated with radiation, The ceil treated with 5-FU and fellowed by radiation within 24 hrs had cell with increased number of hypodiploidy cells. Almost same type of chromosomal changes were reproduced in cells treated with combined treatment with radiation and 5-FU. Minor differences were that cells with fewer number of chromosome were more frequent in cells treated with combined therapy. Further increase in cells of hypoploidy (93%) having 1-10 chromosome were induced by additional radiation. Therefore, the enhanced therapeutic effect of 5-FU combined with radiation of A549 cells appeared to be additive rather than synergistic.

• 대한물리의학회지
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• 제18권3호
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• pp.39-45
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• 2023

PURPOSE: This study aimed to provide the basic data necessary for rehabilitation by identifying the effects of complex balance exercises combined with self-observation training on balance and gait improvement in stroke patients. METHODS: This study assigned 20 people randomly into two groups: the control and experimental groups. The experimental group (10 subjects) underwent self-observation training-combined complex balance exercise. The control group (10 subjects) underwent complex balance exercises. A pretest of the balance ability and walking ability of both groups was performed. The interventions were conducted for 30 minutes three times a week for four weeks, and post-tests were conducted four weeks after all interventions were completed. RESULTS: There was a significant difference between the experimental and control groups according to the increase in Berg Balance Sale within the group and a statistically significant difference by a decrease in 10MWT (p < .01). On the other hand, there was a significant difference only in the change in Berg Balance Sale between the two groups (p < .05). CONCLUSION: Combined balance exercise combined with self-observation training and combined balance exercise alone positively affected the Berg Balance Sale and 10MWT in both groups. On the other hand, in the results between groups, there was a statistically significant difference in Berg Balance Sale in complex balance exercise combined with self-observation training. Therefore, self-observation training should be used for the rapid social rehabilitation of stroke patients.

• 한국전문물리치료학회지
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• 제11권3호
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• pp.1-9
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• 2004

Most exercise for Patellofemoral pain syndrome (PFPS) has focused on selectively strengthening the vastus medialis oblique muscle (VMO). Although open chain knee extension exercises are effective for increasing overall quadriceps strength, they are not always indicated for PFPS rehabilitation. This study was designed to identify the effect of combined posture of lower extremity on Electromyographic (EMG) activity of the vastus lateralis muscle (VL) and VMO during static squat exercises. The subjects were twenty young adult males who had not experienced any knee injury and their Q-angle was within a normal range. They were asked to perform static squat exercises in five various postures using their lower extremities. The EMG activity of the VL and VMO were recorded in five exercises by surface electrodes and normalized by %MVC values derived from seated, isometric knee extensions. The normalized EMG activity levels (%MVC) of the VL and VMO for the five postures of the lower extremities were compared using one way ANOVA with repeated measures. Results of repeated measures of ANOVA's revealed that exercise 3 and exercise 5 produced significantly greater EMG activity of VMO/VL ratios than exercise 1 (p<.05). When the static squat exercise was combined with hip adduction and toes pointed outwardly, the EMG activity of VMO/VL rates was increased. The EMG activity of VMO/VL ratio was highest during static squat exercises performed on a decline squat. These results haveimportant implications for progressive and selective VMO muscle strengthening exercises in PFPS patients.