• The Journal of Korean Physical Therapy
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• v.31 no.1
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• pp.49-55
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• 2019

Purpose: This study examined the effects of taping therapy on the balance and gait of stroke patients. Methods: The subjects of this study were 30 stroke patients. The treatment groups were prescribed a combination of taping, therapy applied simultaneously to the ankle and the hip joint, and general physical therapy twice a day for 30 minutes each, five days per week for 4 weeks for a total of 40 times. The control group was treated with general physical therapy for 30 minutes, 5 times per week for 4 weeks, and total 40 times. All subjects were followed up on a Berg balance scale, timed up and go test, activity-specific balance confidence scale, and GaitRite. Results: The group that simultaneously received taping therapy to the ankle and hip joint showed more significant effects than the group treated with ankle joint taping only (p<0.05). Effects were noted in the Berg balance scale, timed up and go test, activity-specific balance confidence scale and gait ability test. Compared to the control group, the group treated at the ankle and hip joint showed significant effects after the experiment in the Berg balance scale, timed up and go test, activity-specific balance confidence scale, and gait ability test (p<0.05). Conclusion: Taping therapy applied to both the ankle and hip joints, and combined with general physical therapy appears to be effective in patients with chronic stroke who have an impaired balance and gait ability.

• Physical Therapy Rehabilitation Science
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• v.9 no.4
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• pp.215-221
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• 2020

Objective: Tension-type headaches usually occur with temporomandibular disorder, which increases the risk of the chronic tension-type headaches. This study was conducted to investigate the effect of additional temporalmandibular therapy compared to cerivcal joint therapy for tension-type headaches with pericranial tenderness. Design: Randomized controlled trial. Methods: Forty-one patients with chronic tension-type headaches and pericranial tenderness were randomized into the 3 groups, such as the temporomandibular joint therapy group (TMJT group, n=14), cervical manual therapy group (CMT group, n=14) and conservative therapy group (CT group, n=13). All patients were assessed at baseline and after each intervention during the three sessions. The participants in the TMJT group received the temporomadibular joint treatment and cervical manual therapy for 30 minutes, once a week, for 3 weeks. The participants in the CMT group received the cervical manual therapy, and those in the CT group received modalities during same time period. The outcome measurements used were the intensity of headaches measured on the Visual Analogue Scale (VAS), quality of life measured with the Headache Impact Test (HIT-6), and function of the cervical spine using the Neck Diability Index (NDI). Results: The TMJT group that received temporomandibular joint treatment and cervical manual therapy showed a significant decrease in VAS, HIT-6, and NDI compared with the other 2 groups (p<0.05). Conclusions: This study suggected that temporomandibular joint treatment combined with cervical manual therapy was more effective for the chronic tension-type headaches with pericranial tenderness than the usual cervical therapy alone.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8429-8433
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• 2014

Circulating tumor cells (CTCs) are believed to be particularly important and a reliable marker of malignancy. However, the prognostic significance of CTCs detected in patients with small cell lung cancer (SCLC) is still unclear. We therefore aimed to assess the prognostic relevance of CTCs using a meta-analysis. We searched PubMed for relevant studies and statistical analyses were conducted to calculate the hazard ratio (HR) and 95% confidence intervals (CIs) using fixed or random-effect models according to the heterogeneity of included studies. A total of 7 papers covering 440 SCLC patients were combined in the final analysis. The meta-analysis revealed that CTCs were significantly associated with shorter overall survival (HR=1.9; 95%CI: 1.19-3.04; Z=2.67; P<0.0001) and progression-free survival (HR=2.6; 95%CI: 1.9-3.54; Z=6.04; P<0.0001). The results thus suggest that the presence of CTCs indicates a poor prognosis in patients with SCLC. Further well-designed prospective studies are required to explore the clinical applications of CTCs in SCLC.

• Journal of the Korean Society of Physical Medicine
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• v.12 no.3
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• pp.43-47
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• 2017

PURPOSE: The purpose of this study was to identify the effects of physical therapy plus Kinesio taping (KT) on muscle tone and stiffness in patients with shoulder pain. METHODS: This study included 22 participants who were divided into the experimental group (n=11) who underwent a routine physical therapy with KT and the control group (n=11) who received the same physical therapy only. The physical therapy consisted of heat application and electrical stimulation. Heat was applied for 10 minutes and electrical stimulation was conducted for 20 minutes. Intervention was provided over a 1-week period, and frequency for muscle tone and stiffness was measured to determine changes in shoulder muscle status. The muscles were supraspinatus and deltoid. Measurements were taken before, after 1day, 3day and after 1 week to identify time-dependent effects of intervention. RESULTS: The effects of the intervention were significant in both groups, and effects were greater in the experimental group. Changes in muscle tone and stiffness were statistically significant in both groups and at varying time points (p<.05). CONCLUSION: Based on the improved muscle performance found in this study, KT is considered an effective intervention strategy for patients with shoulder pain when it is combined with conventional physical therapy.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.5
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• pp.870-875
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• 2011

Arthritis of the knee is the most common type of joint inflammatory disorder and it is associated with pain and inflammation of the joint capsule. The aim of present study was to investigate the endogenous effect of low intensity laser acupuncture on collagen-induced arthritis in rats. Forty Sprague-Dawley rats were randomly divided into normal group, arthritis group, low laser group with 10 rats in each group. Arthritis in rats was induced by subcutaneous injection of type II collagen combined with complete Freund's adjuvant. Here we investigated the effects of low intensity laser therapy in experimentally induced rat knee arthritis. To evaluate preventive and therapeutic effects of low intensity laser acupuncture on collagen-induced arthritis rats. In collagen induced arthritic rats, there was significant increase in rat paw volume and decrease in body weight increment, whereas low intensity laser therapy groups, showed significant reduction in paw volume and normal gain in body weight. The altered biochemical parameters(blood urea, serum creatinine, total proteins and acute phase proteins) in the arthritic rats were significantly brought back to near normal by the low intensity laser therapy. Therefore, low intensity laser acupuncture may be a useful treatment in the prevention and treatment of collagen-induced arthritis.

• Journal of Acupuncture Research
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• v.19 no.5
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• pp.176-188
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• 2002

Objective : Sono-acupoint (SA) therapy is a new therapeutic technique that combined with acupuncture points, herbal medicine and ultrasound therapy. This study was carried out to investigate the analgesic and anti-inflammatory effects of sono-acupoint therapy. Methods : We performed the tail-flick test with normal rats to examine the tail-flick latency (TFL), and the Freund's adjuvant-induced arthritis rat model to examine the edema, skin temperature and serum concentration of c-reactive protein and rheumatoid factor (RF). Herbal SA (HSA) treatment was performed at bilateral Zusanli (ST36) with the hanbang-gel made of several selected herbal drugs in Sprague-Dawley rats (male, $250{\pm}30g$). General SA (GSA) treatment was performed at bilateral Zusanli (ST36) with the gel used in ultrasound therapy. In arthritis rat model, Freund's adjuvant (50mg/ml) was injected in dorsal part of right foot, and these treatments were performed after 15 days. Results : TFL was lengthened after SA treatments. Skin temperature and RF concentration that were the evidence of arthritis in rats were decreased by HSA treatment (P < 0.05). Conclusion : These results indicate that HSA has the analgesic and anti-inflammatory effects in rats, and further developments will produce the advance of this new therapeutic skill.

• Journal of Korean Medicine for Obesity Research
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• v.1 no.1
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• pp.33-42
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• 2001

Objectives: This study was to investigate the reductive effects of oriental medicine on the body fat and abdominal obesity, Methods: The subject were selected among the patients who were treated with 4weeks total program, visited our obesity clinic from October 1999 to August 2000, We practiced combined therapy such as herbal medicine, acupuncture therapy, moxibution therapy, negative therapy, auricular acupuncture, electrolipolysis, colon hydrotherapy, heat therapy, Chuna therapy, low-calorie diet teaching, exercise teaching, and correcting life style for 4 weeks. Results and Conclusion: 1. Body weight, RBW, and BMI were significantly reduced each by 5.4kg, 10.4% and $2.2kg/m^2$ (p<0.01). 2. % Body fat was significantly reduced by 3.3%. Fat mass was reduced by 4.0kg(17.0%) and soft lean mass was reduced by 1.5kg(3.7%), thus it was acknowledged that fat mass was significantly reduced compared to soft lean mass by oriental medicine treatment for obesity. 3. WHR was significantly reduced by 0.02. Waist circumference was reduced by 6cm(6.6%) and hip circumference was reduced by 4.5cm(4.6%), thus it was acknowledged that waist fat was significantly reduced compared to hip circumference by oriental medicine treatment for obesity.

• The Journal of Internal Korean Medicine
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• v.22 no.3
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• pp.393-396
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• 2001

Objectives: We were to assess the effectiveness of combined therapy of Oriental Medicine and Western Medicine on acute stroke. Methods: We selected acute middle cerebral artery territory infarction subjects, within 3 days after stroke onset, who had never have any type of stroke history before. The subjects, admitted to department of Oriental Medicine, received combination therapy of western medical treatment including thrombolytic, anticoagulant, or antiplatelet agents and oriental medical treatment including acupuncture and herbs medication. The other subjects, admitted to department of Neurology, received only modern western medical treatment. The National Institute of Health Stroke Scale (NIHSS) was checked at admission, 1 week and 2 weeks later to assess neurologic improvement. The Modified Barthel Index (MBI) was checked 1 week and 2 weeks after admission to motor function recovery. Results: Comparing the NIHSS between baseline and 1 week later, the combination therapy group showed more improvement than the single-treated with anticoagulants group. However, there was no significant difference between the two groups, comparing 1 week and 2 weeks later with the NIHSS and the MBI. Conclusions: Combination therapy have more beneficial effect on acute stage of stroke.

• Physical Therapy Rehabilitation Science
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• v.10 no.3
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• pp.278-288
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• 2021

Objective: The purpose of this study is to investigate the effect of stabilization exercise on whole-body vibration on pain, dysfunction, psychosocial factors, balance ability, and abdominal contraction with patients with low back pain. Design: A randomized controlled trial Methods: A total of 34 patients with low back pain were assigned randomly to experimental group (n=17) and control group (n=17). Both groups underwent a neuromuscular stabilization exercise program. In addition, the experimental group implemented the neuromuscular stabilization exercise program using whole-body vibration. All interventions were applied 60 min per session, 3 times per week for total 4 weeks. Numeric Rating Scale (NRS), Korean version of Oswestry Disability Index (K-ODI), Fear-Avoidance Beliefs Questionnaire (FABQ), balance ability, muscle thickness and contraction ratio were compared to evaluate the effect on intervention. Results: Both groups showed significant differences in NRS, balance ability, and muscle thickness in contraction, contraction ratio before and after intervention (p<0.05). In addition, the experimental group showed significant difference in the amount of change in NRS, balance ability and muscle thickness in contraction, contraction ratio values than the control group (p<0.05). Conclusions: Neuromuscular stabilization exercise program combined with whole-body vibration stimulation has been proven to be an effective and clinically useful method to decrease pain, dysfunction, increase balance ablilty, and transverse abdominis muscle thickness in contraction and contraction ratio for patients with low back pain.

• Journal of Gastric Cancer
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• v.21 no.3
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• pp.319-324
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• 2021

The abscopal effect refers to the phenomenon in which local radiotherapy is associated with the regression of metastatic cancer that is distantly located from the irradiated site. Here, we present a case of a patient with advanced gastric cancer and brain metastases who was successfully treated with brain radiotherapy and anti-programmed death-1 (PD-1) therapy-induced abscopal effect. Although anti-PD-1 therapy alone could not prevent disease progression, the metastatic lesions in the brain and also in the abdominal lymph node showed a drastic response after brain radiotherapy and anti-PD-1 therapy. To our knowledge, this is the first reported case of successful treatment of advanced gastric cancer with multiple brain and abdominal lymph node metastases, possibly through anti-PD-1 therapy combined with brain radiotherapy-induced abscopal effect. We suggest that the combination of brain radiotherapy and anti-PD-1 therapy may be considered as a therapeutic option for advanced gastric cancer, especially when there is brain metastasis.