• 대한감각통합치료학회지
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• 제11권2호
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• pp.13-26
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• 2013

목적 : 본 연구는 실행장애 아동에게 맞게 고안된 개별치료와 또래와 함께 실시한 그룹치료를 병행한 감각통합치료가 작업수행능력에 미치는 효과에 대해 알아보고자 하였다. 연구방법 : 연구 대상은 2012년 만 5세 11개월의 남아로 작업수행을 의존하여 감각통합치료에 의뢰되었다. 연구설계는 개별실험연구(single-subject research design) 중 ABA설계를 사용하였다. 연구 과정은 기초선 기간 4회기, 중재 기간 24회기로 총 12주간 각 주1회씩 개별치료와 그룹치료를 병행하여 감각통합치료를 실시하였다. 실험기간동안 목표성취척도(Goal Attainment Scale: GAS)를 통하여 체성감각변별능력과 자세조절능력에 따른 감각통합능력의 변화되는 과정을 측정하였고 기초선평가와 재평가를 통해 작업수행능력을 측정하였다. 결과 : 개별치료와 그룹치료를 병행한 감각통합치료는 체성실행장애 아동의 체성감각변별능력과 자세조절능력의 향상과 함께 작업수행기술의 성취에 효과가 있었다. 결론 : 본 연구를 통하여 개별치료와 그룹치료를 병행한 감각통합치료는 체성실행장애 아동의 적응반응에 긍정적인 영향을 미치는 것을 알 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9667-9672
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• 2014

Background: Pancreatic adenocarcinoma is a malignant gastrointestinal cancer with significant morbidity and mortality. Despite severe side effects of chemotherapy, the use of immunotherapy combined with chemotherapy has emerged as a common clinical treatment. In this study, we investigated the efficacy of the combined doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) therapy on murine pancreatic cancer Panc02 cells in vitro and in vivo and underlying mechanisms. Materials and Methods: A Panc02-bearing mouse model was established to determine whether doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) could effectively inhibit tumor growth in vivo. Cytotoxicity of natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) was evaluated using a standard LDH release assay. To evaluate the relevance of NK cells and CD8 T cells to the combination therapy-mediated anti-tumor effects, they were depleted in tumor-bearing mice by injecting anti-asialo-GM-1 antibodies or anti-CD8 antibodies, respectively. Finally, the influence of doxorubicin+interferon-${\alpha}$ (IFN-${\alpha}$) on the ligands of NK and T cells was assessed by flow cytometry. Results: The combination therapy group demonstrated a significant inhibition of growth of Panc02 in vivo, resulting from activated cytotoxicity of NK cells and CTLs. Depleting CD8 T cells or NK cells reduced the anticancer effects mediated by immunochemotherapy. Furthermore, the doxorubicin+IFN-a treatment increased the expression of major histocompatibility complex class I (MHC I) and NKG2D ligands on Panc02 cells, suggesting that the combined therapy may be a potential strategy for enhancing immunogenicity of tumors. All these data indicate that the combination therapy using doxorubicin and interferon-${\alpha}$ (IFN-${\alpha}$) may be a potential strategy for treating pancreatic adenocarcinoma.

• 재활치료과학
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• 제6권2호
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• pp.71-83
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• 2017

Objective: This study was to develop and verify the effects of the exercise-cognitive combined dual-task training program on cognitive function and depression of the elderly with mild cognitive impairment(MCI). Methods: The subjects were randomly assigned to the exercise-cognitive combined dual-task training group(n=32) or single-task training group(n=31). To identify the effects on cognitive function, general cognitive function, frontal lobe function, and attention/working memory were measured. Depression was evaluated using Korean version of Geriatric Depression Scale. The outcome measurements were performed before and after the 8 weeks of intervention(2 days per week). Results: After 8 weeks, general cognitive function, frontal cognitive function, attention/working memory function, depression of the dual-task training group were significantly increased than those of the single-task training group(p<0.05). Conclusion: The results indicated that an exercise-cognitive combined dual-task training for MCI was effective in improving general cognitive function, frontal /executive function, attention/working memory function and reducing depression.

• 국제물리치료학회지
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• 제4권2호
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• pp.600-604
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• 2013

The purpose of this study was to implement a program of combined muscle stregth and proprioceptive exercises and to examine the impacts of these exercises on functional ankle instability(FAI). Experiments were conducted with 30 adult males and females in their 20s, and the exercise programs were implemented three days per week for four weeks. FAI was defined as a feeling of giving way after an ankle sprain and having a Cumberland ankle instability tool score of 24 points or less. The study subjects were randomly assigned to either a control group, a muscle-strengthening exercise group, or a combined muscle-strengthening and proprioceptive exercise group consisting of 10 subjects each. A Biodex isokinetic dynamometer was used to assess the subjects'ankle strength at selected speeds of $60^{\circ}/sec$ and $120^{\circ}/sec$. The peak torque % body weight showed significant differences in plantar flexion, dorsiflexion, inversion, and eversion. There were also significant differences in proprioception. The results suggest that applying combined muscle-strength and proprioceptive exercises to subjects with FAI is a more effective intervention than applying only muscle-strengthening exercises.

• 한방비만학회지
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• 제15권2호
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• pp.137-143
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• 2015

The purpose of this study is to investigate the clinical studies of cupping therapy for obesity in Traditional Chinese Medicine (TCM) and to evaluate the effects of it for use in practice. CNKI were searched for controlled studies on cupping therapy for obesity that were published up to September 2015. The review included 9 randomized controlled trials, and we analyzed the objectives, process of interventions, outcome measurements, and main results of the studies. We found that cupping therapy combined with acupuncture, electric acupuncture or thread embedding have more effectively decreased body mass index, waist circumference and lipid profile than acupuncture, electric acupuncture or thread embedding only have done. In the reviewed studies, cupping therapy treated in the region of abdomen, upper and lower limbs, and dorsal part operating on 5 to 25 minutes for one time with total 6 to 45 times of schedule. In this study, we demonstrated that cupping therapy combined with acupuncture, electric acupuncture or thread embedding could have effectively used for treating obesity. Further evaluation and clinical researches are required to establish evidence in practice.

• 대한한방부인과학회지
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• 제30권4호
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• pp.59-76
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• 2017

Objectives: The purpose of this study is to investigate the effect on both herbal medicine periodic therapy and western medicine for polycystic ovary syndrome subfertility. Methods: We searched 8 electronic databases and search keywords were 'PCOS' and 'periodic therapy' or 'cyclic treatment'. We included randomized controlled clinical trials (RCTs) using the periodic therapy combined western medicine for PCOS patients. Results: We selected 8 studies. In studies, there were three studies in which the menstrual cycle was divided into 2 periods, one study divided into 3 periods, and four study divided into 4 periods. The meta-analysis of the 7 trials indicated that pregnancy rates integrated clomiphene and periodic therapy were higher than clomiphene alone. Conclusions: The periodic therapy combined western medicine for PCOS subfertility patients seems to improve pregnancy rates from this research. However, this result should be taken cautiously by unclear risk of bias. It would be necessary to fulfill further clinical study with herbal medicine periodic therapy on PCOS in Korean medicine to establish standard evidence of them.

• 턱관절균형의학회지
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• 제13권sup호
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• pp.15-20
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• 2023

Objectives: This case is to report the effect of TMJ balancing therapy (TBT) and combined Korean Medicine (CKM) on a 15-year-old male patient with suspected cervical dizziness of unknown causes. Methods: He was treated with TBT and CKM included Yin-yang Balancing Therapy of TMJ, pelvic balancing therapy, cervical chuna therapy once a week for 3 months. He continued to wear accurate balancing appliance (ABA) in the mouth, did 12-way cervical gravity straightening exercise and took banhabakchulchunma-tang-gamibang for 3 months. The effects of treatment was evaluated using the numerical rating scale (NRS). Results: After the treatments, dizziness was relieved from NRS 7 to NRS 1. Conclusions: This case report suggests that TBT and CKM treatments can relieve suspected cervical dizziness of unknown causes.

• 한국엔터테인먼트산업학회논문지
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• 제14권1호
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• pp.159-166
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• 2020

본 연구는 건강한 20대 성인 20명을 대상으로 3D Newton box를 이용한 PNF의 통합패턴 운동을 실시한 후 균형, 고유감각, 유연성의 즉각적인 효과를 알아보기 위해 시행되었다. 본 연구에서 수집된 자료는 SPSS Window 19.0 통계 프로그램을 이용하여 분석하였으며, 대상자들의 일반적 특성은 기술통계를 사용하여 평균과 표준편차를 산출하였고 집단 내 균형, 고유감각, 유연성의 전·후 차이는 대응 표본 t-검정으로 분석하였다. 대상자들의 균형, 고유감각, 유연성을 Y-balance, 눈 고 한 발 서기, 손가락 바닥 닿기를 이용하여 측정하였고, 운동은 3D Newton box 안에서 PNF의 통합패턴을 적용하였다. 운동 후 균형, 고유감각, 유연성 모두 유의하게 증가하였다. 이와 같은 결과를 통해 3D Newton box를 이용한 PNF의 통합패턴 운동이 20대 성인의 균형, 고유감각, 유연성에 즉각적으로 효과가 나타남을 알 수 있었다. 따라서 균형, 고유감각, 유연성의 감소로 인해 손상 위험도가 높은 성인 또는 환자에게 적극적으로 활용될 수 있는 운동이라고 사료된다.

• 대한물리의학회지
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• 제10권1호
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• pp.53-61
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• 2015

PURPOSE: This study examined the effect of the combined exercise program on physical fitness and related hormone in elderly women. METHODS: The subjects included 40 elderly women who reside at B city. Upon thire agreements, the subjects were divided into either an experimental group and the control group. there 20 subjects in each. The combined exercise program was conducted during the 8 weeks, and the experimental group was underwent its associated program 5 times a week. there wear 2 subjects from each group that were excluded. The physical fitness wear measured and the related hormone(growth hormone, DHEA) were taken with blood serum density. RESULTS: After 8 weeks for intervention, there were statistically significant differences between in physical fitness and growth hormone, DHEA in experimental group(p<.05). however, this difference was not significantly different in the control group. Futher, there wear statistically significant difference between two group of all item(p<.05). CONCLUSION: The findings of this study show that combined exercise program helps the physical fitness and increase of growth hormone, DHEA in elderly women. In conclusion, the regular combined exercise program for 8 weeks is effective for increase physical fitness and related hormone in elderly women, and positive influence upon, thereby being thought to be able to lower risk in aging and weakness.

• 부모자녀건강학회지
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• 제10권1호
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• pp.65-76
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• 2007

Purpose: This study was to determine the effects of a combined obesity management program in obese women. The study also attempted to measure the effects of the program on blood lipid, body mass index, dietary calory and dietary habit. Method: This research employed a one group pretest-posttest design. A total of 251 obese women(BMI: over 25) were selected for this research. The subjects in a combined obesity management program (combined exercise therapy and dietary therapy) for 8weeks. Results: After performing the program for 8 weeks, the result were follows. 1) There were significant reduction in total cholesterol(t=4.10, p= .00), triglyceride(t=5.09, p= .00) but no significant reduction BMI. 2) There were reduction in dietary calory, but no significantly. 3) There were significant increase in dietary habit. Conclusion: From these findings, it was confirmed that a combined obesity management program for obese women can decrease TC, TG, BMI and increase dietary habit. Therefore, this program can be utilized for various population groups including women, and further researches are required on program for men, elderly.