• Title/Summary/Keyword: combined systems

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High-Resolution Microarrays for Mapping Promoter Binding sites and Copy Number Variation in the Human Genome

  • Albert Thomas
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2006.02a
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    • pp.125-126
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    • 2006
  • NimbleGen has developed strategies to use its high-density oligonucleotide microarray platform (385,000 probes per array) to map both promoter binding sites and copy number variation at very high-resolution in the human genome. Here we describe a genome-wide map of active promoters determined by experimentally locating the sites of transcription imitation complex binding throughout the human genome using microarrays combined with chromatin immunoprecipitation. This map defines 10,567 active promoters corresponding to 6,763 known genes and at least 1,196 un-annotated transcriptional units. Microarray-based comparative genomic hybridisation (CGH) is animportant research tool for investigating chromosomal aberrations frequently associated with complex diseases such as cancer, neuropsychiatric disorders, and congenital developmental disorders. NimbleGen array CGH is an ultra-high resolution (0.5-50 Kb) oligo array platform that can be used to detect amplifications and deletions and map the associated breakpoints on the whole-genome level or with custom fine-tiling arrays. For whole-genome array CGH, probes are tiled through genic and intergenic regions with a median probe spacing of 6 Kb, which provides a comprehensive, unbiased analysis of the genome.

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Signal Control and Dynamic Route Guidance in ITS (지능형 교통체계에서의 신호제어와 동적 경로안내)

  • 박윤선
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.22 no.50
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    • pp.333-340
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    • 1999
  • An ideal traffic control system should consider simultaneously both route guidance of vehicles and signal policies at intersection of a traffic network. It is known that an iterative procedure gives an optimal route to each vehicle in the network. This paper presents an iterative procedure to find an optimal signal plan for the network. We define the optimal solution as a signal equilibrium. From the definition of signal equilibrium, we prove that the fixed point solution of the iterative procedure is a signal equilibrium, when optimal signal algorithms are implemented at each intersection of the network. A combined model of route guidance and signal planning is also suggested by relating the route guidance procedure and the signal planning procedure into a single loop iterative procedure.

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Graphonomy research of wooden member terms in Yeonggeon-euigwe (영건의궤(營建儀軌)의 목부재(木部材) 용어(用語)에 관(關)한 문자학적(文字學的) 연구(硏究))

  • Kim, Jae-Ung
    • Journal of architectural history
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    • v.18 no.1
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    • pp.67-89
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    • 2009
  • This study examines the examples of wooden member terms of architecture terminology used in Yeonggeon-euigwe(營建儀軌) in the era of Joseon Dynasty. It is to trace the period of their appearances and changes and also to illuminate coinage characteristics and method of architectural terminology used in Yeonggeon-euigwe through graphonomy research and system and structure of wood member terms. By analyzing the meaning of a word, it was found that there was much Insineui, difference of word meaning by country was shown although it was the same shape of character. In particular, the specialty of double language system of Korean language is combined with that of wood terms. Operation of type unrelated to word meaning was found and Korean unique Gachaeui(假借義) like Bo(褓) was generated. This study draws separate systems: one is that can indicate coinage characters of architectural terminology in Yeonggeon-euigwe. The other is to obtain coinage method as a result of reclassifying terminology based on it.

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Bio-Adhoc Sensor Network for Disaster Emergency Management Systems (재난 관리용 시스템을 위한 센서 탑재 바이오 Ad hoc 네트워크 구축방안 연구)

  • Lee, Dong-Eun;Lee, Goo-Yeon
    • Proceedings of the IEEK Conference
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    • 2006.06a
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    • pp.775-776
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    • 2006
  • Ad hoc network does not need any preexisting network infrastructure, and it has been developed as temporal networks in the various fields. Infostation is an efficient system to transfer information which does not have delay sensitive characteristics. In this paper, we propose a disaster emergency management system using sensor attached animals' mobility combined with infostation system. We also analyze the performance of the proposed system. From the performance analysis results, we expect that the proposed system will be very useful to early detect big forest fires which occurs frequently in Korea mountain areas.

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An Integrated Model of SPC and EPC with Second-order Autoregressed Disturbance for the Process with Trend (추세가 있는 공정에서 이계자기회귀 각란 모형을 고려한 EPC와 SPC의 통합시스템)

  • 김종걸;정해운
    • Proceedings of the Safety Management and Science Conference
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    • 2002.05a
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    • pp.81-89
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    • 2002
  • EPC seeks to minimize variability by transferring the output variable to a related process input(controllable) variable, while SPC seeks to reduce variability by detecting and eliminating assignable causes of variation. In the case of product control, a very reasonable objective is to try to minimize the variance of the output deviations from the target or set point. We consider an alternative EPC model with second-order autoregressive disturbance. We compare three control systems; EPC, EPC combined with EWMA, and Shewhart. This paper shows through simulation that the performance of the integrated model of EPC and SPC is more preferable than that of EPC.

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Kinematics of the Envelope and Two Bipolar Jets in L1157

  • Kwon, Woojin;Fernandez-Lopez, Manuel;Stephens, Ian W.;Looney, Leslie W.
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.1
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    • pp.72.3-72.3
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    • 2016
  • A massive envelope and a strong bipolar outflow are the two most distinct structures of youngest protostellar systems. We present observational results from the Combined Array for Research in Millimeter-wave Astronomy (CARMA) toward the youngest (Class 0) protostellar system L1157. At an angular resolution of 5 arcseconds, we mapped its well-developed outflow in CO 2-1 over a span of approximately 5 arcminutes. Additionally, we imaged the central envelope with CO isotopes, CS, CN, and N2H+ with an angular resolution of about 2 arcseconds. We show that the bipolar outflow may be represented with a two jet model and constrain its physical properties such as precession/rotation directions, velocities, inclinations, and position angles via cube data fitting. In addition, we discuss the kinematic features of the envelope detected in CO isotopes and N2H+ and present the radius-dependent dust opacity spectral index.

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A Modified MMSE Algorithm for Adaptive Antennas in OFDM/CDMA Systems

  • Su, Pham-Van;Tuan, Le-Minh;Kim, Jewoo;Giwan Yoon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2002.05a
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    • pp.509-513
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    • 2002
  • This paper presents a semi-blind Minimum Mean Square Error (MMSE) beamforming adaptive algorithm used far OFDM/CDMA combined system. The proposed algorithm exploits the transmitting pilot signal in the initial period of the transmission to update the weight vector. Then it applies the blind adaptive period to update the weight vector, in which the pilot signal is no longer used. The derivation of the algorithm based on the Mean Square Error (MSE) criterion is also presented. Computer simulation is carried out to verify the performance of the proposed approach.

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Very Efficient Maximum-Likelihood and Sub-Optimal Decoders for V-BLAST

  • Le Minh-Tuan;Pham Van-Su;Yoon Gi-Wan
    • Journal of information and communication convergence engineering
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    • v.4 no.1
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    • pp.5-9
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    • 2006
  • In this paper, a low-complexity ML decoder based on QR decomposition, called LCMLDec decoder, is proposed for the V-BLAST with 2 transmit antennas. Then, it is combined with other suboptimal interference nulling and cancelling decoders originated form QR decomposition such as sorted QR or MMSE-SQRD decoder to generate efficient decoders that significantly improve the performance of the V-BLAST with more than 2 transmit antennas, at the expense of a small increase in complexity. Simulation results are provided to demonstrate the performances and complexities of the proposed decoders.

A Study on Developing Fold-Over Designs with Four-Level Quantitative Factors (4-수준 계량인자가 포함된 반사계획에 관한 연구)

  • Choi, Kiew-Phil;Byun, Jai-Hyun
    • Journal of Korean Institute of Industrial Engineers
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    • v.28 no.3
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    • pp.283-290
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    • 2002
  • Two-level fractional factorial designs are widely used when many factors are considered. When two-level fractional factorial designs are used, some effects are confounded with each other. To break the confounding between effects, we can use fractional factorial designs, called fold-over designs, in which certain signs in the design generators are switched. In this paper, optimal fold-over designs with four-level quantitative and two-level factors are presented for (1) the initial designs without curvature effect and (2) those with curvature effect. Optimal fold-over design tables are provided for 8-run, 16-run, and 32-run experiments.

Usability of Wireless Application Protocol Interface in the Philippines

  • Tangsoc, Jazmin Chong;Ponio V., Amelia S.
    • Industrial Engineering and Management Systems
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    • v.8 no.1
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    • pp.54-65
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    • 2009
  • The existence of Internet revolutionized the computer and communications world. With the rising demand for accessing the Internet, the mobile technology has incorporated the use of Internet in mobile phones. Wireless Application Protocol (WAP) has combined two of the widest utilized technology today: mobile phones and Internet. This study aims to assess the existing WAP pages offered by the top service providers in the Philippines through usability testing experiments. The paper also aims to identify existing problems in WAP interface by focusing on the errors committed by the users. From the usability study, it was found out that common usability problems are wrong selection of links, unclear grouping of categories, wrong feedback, and redundant links. The type of service provider used is significant in determining the performance of users while experience in accessing WAP is insignificant.