• International Journal of Fuzzy Logic and Intelligent Systems
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• 제5권1호
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• pp.21-28
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• 2005

This paper proposes a new method for accelerating the search speed of genetic algorithms by taking derivative evaluation and conditional random selection into account in their evolution process. Derivative evaluation makes genetic algorithms focus on the individuals whose fitness is rapidly increased. This accelerates the search speed of genetic algorithms by enhancing exploitation like steepest descent methods but also increases the possibility of a premature convergence that means most individuals after a few generations approach to local optima. On the other hand, derivative evaluation under a premature convergence helps genetic algorithms escape the local optima by enhancing exploration. If GAs fall into a premature convergence, random selection is used in order to help escaping local optimum, but its effects are not large. We experimented our method with one combinatorial problem and five complex function optimization problems. Experimental results showed that our method was superior to the simple genetic algorithm especially when the search space is large.

• 산업경영시스템학회지
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• 제23권61호
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• pp.105-114
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• 2000

Job Shop Problem which consists of the m different machines and n jobs is a NP-hard problem of the combinatorial optimization. Each job consists of a chain of operations, each of which needs to be processed during an uninterrupted time period of a given length on a given machine. Each machine can process at most one operation at a time. The purpose of this paper is to develop the heuristic method to solve large scale scheduling problem using Constraint Satisfaction Problem method and Simulated Annealing. The proposed heuristic method consists of the search algorithm and optimization algorithm. The search algorithm is to find the solution in the solution space using CSP concept such as backtracking and domain reduction. The optimization algorithm is to search the optimal solution using SA. This method is applied to MT06, MT10 and MT20 Job Shop Problem, and compared with other heuristic method.

• 한국컴퓨터정보학회논문지
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• 제20권9호
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• pp.21-29
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• 2015

The set partitioning problem is a well-known NP-hard combinatorial optimization problem, and it is formulated as an integer programming model. This paper proposes an Integer Programming-based Local Search for solving the set partitioning problem. The key point is to solve the set partitioning problem as the set covering problem. First, an initial solution is generated by a simple heuristic for the set covering problem, and then the solution is set as the current solution. Next, the following process is repeated. The original set covering problem is reduced based on the current solution, and the reduced problem is solved by Integer Programming which includes a specific element in the objective function to derive the solution for the set partitioning problem. Experimental results on a set of OR-Library instances show that the proposed algorithm outperforms pure integer programming as well as the existing heuristic algorithms both in solution quality and time.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권5호
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• pp.2162-2176
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• 2018

Chemical reactions have an intricate relationship with the search for better-quality neighborhood solutions to optimization problems. A catalytic reaction for chemical reactions provides a clue and a framework to solve complicated optimization problems. The application of a catalytic reaction reveals new information hidden in the optimization problem and provides a non-intuitive perspective. This paper proposes a new simulated catalytic reaction method for search in optimization problems. In the experiments using this method, significantly improved results are obtained in almost all graphs tested by applying to a graph bisection problem, which is a representative problem of combinatorial optimization problems.

• 산업경영시스템학회지
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• 제23권59호
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• pp.37-42
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• 2000

The parallel machines scheduling problems is one of the combinatorial optimization problems that often occurs in the real world. This problem is classified into two cases, one of which is the case which processing time are identical and the other, nonidentical. Not so much researches have been made on the case that nonidentical parallel machines scheduling problem. This study proposes Tabu Search methods for solving parallel machines scheduling problems related to due dates: minimizing mean tardiness, minimizing the number of tardy jobs, minimizing the maximum tardiness.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.232.1-232.1
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• 2003

Bradykinin is an autocoid related to acute and chronic pain and inflammation. The non-peptide bradykinin antagonists are of interest as novel anti-inflammatory therapeutics and some active compounds such as FR 173657, LF 16-0687, and bradyzide were reported very recently. In our search for the new bradykinin antagonists, we designed to synthesize the analogues of FR173657 with two to three amide bonds and lipophilic ring system in each molecule. (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.186.1-186.1
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• 2003

Bradykinin is an autocoid related to acute and chronic pain and inflammation. The non-peptide bradykinin antagonists are of interest as novel anti-inflammatory therapeutics. Some active compounds such as FR 173657, LF 160687, and bradyzide were reported very recently. In our search for the new bradykinin antagonists, we designed and synthesized the iminodiacetic acid derivatives having two or three amide bonds and lipophilic ring system in each molecule. Liquid phase combinatorial synthesis using the iminodiacetic acid template gave diverse individual compounds rapidly and efficiently on a 10-50 mg scale. (omitted)

• 대한기계학회논문집A
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• 제26권6호
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• pp.1008-1015
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• 2002

This paper proposes a combinatorial method to compute the global and local solutions of optimization problem. The present hybrid algorithm is the synthesis of a genetic algorithm and a local concentrate search algorithm (simplex method). The hybrid algorithm is not only faster than the standard genetic algorithm, but also gives a more accurate solution. In addition, this algorithm can find both the global and local optimum solutions. An optimization result is presented to demonstrate that the proposed approach successfully focuses on the advantages of global and local searches. Three numerical examples are also presented in this paper to compare with conventional methods.

• 한국경영과학회지
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• 제28권4호
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• pp.191-198
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• 2003

The generalized knapsack problem or gknap is the combinatorial optimization problem of optimizing a nonnegative linear function over the integral hull of the intersection of a polynomially separable 0-1 polytope and a knapsack constraint. The knapsack, the restricted shortest path, and the constrained spanning tree problem are a partial list of gknap. More interesting1y, all the problem that are known to have a fully polynomial approximation scheme, or FPTAS are gknap. We establish some necessary and sufficient conditions for a gknap to admit an FPTAS. To do so, we recapture the standard scaling and approximate binary search techniques in the framework of gknap. This also enables us to find a weaker sufficient condition than the strong NP-hardness that a gknap does not have an FPTAS. Finally, we apply the conditions to explore the fully polynomial approximability of the constrained spanning problem whose fully polynomial approximability is still open.

• Structural Engineering and Mechanics
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• 제43권6호
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• pp.771-794
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• 2012

This paper presents a multi-objective evolutionary algorithm for combinatorial optimisation and applied for design optimisation of fiber reinforced composite structures. The proposed algorithm closely follows the implementation of Pareto Archive Evolutionary strategy (PAES) proposed in the literature. The modifications suggested include a customized neighbourhood search algorithm in place of mutation operator to improve intensification mechanism and a cross over operator to improve diversification mechanism. Further, an external archive is maintained to collect the historical Pareto optimal solutions. The design constraints are handled in this paper by treating them as additional objectives. Numerical studies have been carried out by solving a hybrid fiber reinforced laminate composite cylindrical shell, stiffened composite cylindrical shell and pressure vessel with varied number of design objectives. The studies presented in this paper clearly indicate that well spread Pareto optimal solutions can be obtained employing the proposed algorithm.