• Journal of the Korean Society of Clothing and Textiles
• /
• v.27 no.5
• /
• pp.496-504
• /
• 2003

The purpose of this study was (1) to identify the experimental bias which could appear person perception as results of presentation methods (2) to find out the most desirable method in presentation of stimulus. The research was a quasi experiment and the subjects were 773 male and female undergraduate students. The experimental instruments consisted of a set of stimulus and semantic differential scales of 7- point hi-polar adjectives. The collected data were analyzed by Factor Analysis, ANOVA(analysis of variance), Scheffe＇s multiple range test. The independent variables were presentation orders and presentation time of stimulus. The results were as follows: First, five factors which were potency, sociality, appearance, evaluation, activity impression dimensions emerged to account for the methods of development of stimulus. Second, the presentation order of stimulus in the combination of four stimuli sets had significant effects on the 3 impressional factors(sociality, appearance, evaluation). The presentation order of stimuli in the combination of eight stimuli set had significant effects on the 3 impressional factors(potency, sociality, appearance) and the presentation order of stimuli in the combination of eight stimuli set showed a significant effect on memorization of stimulus and the results support the recency effect. Third, the presentation time of stimuli had significant effects on the 2 impressional factors(potency, activity). 30 seconds presentation as well as free duration time resulted less experimental bias than 3 seconds presentation.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.28 no.3
• /
• pp.1-13
• /
• 2015

Objective : This study investigated the inflammatory reaction is characterized by over production of inflammatory mediators due to an up-regulation of inflammatory pathways.Methods : We investigated the anti-inflammatory effects of water extracts fromLonicera japonicaandScutellaria baicalensisin lipopolysaccharide (LPS)-stimulated U937 cells. Each extract suppressed the production of inflammatory mediators (NO, IL-1${\beta}$, TNF-${\beta}$, and PGE₂) and the expression of inducible NO synthase and cyclooxygenase-2 in LPS- stimulated U937 cells in a dose-dependent manner.Results : These suggest that the suppression effects were synergistically increased by their combination. Their combination extract also inhibited NF-${\kappa}B$-DNA complex of NF-${\kappa}B$ binding activity and translocation of NF-${\kappa}B$ from cytosol to nucleus.Conclusions : Our study suggest that the combination of water-extractable components ofL. japonicaandS. baicalensismay be useful for therapeutic drugs against inflammatory immune diseases, probably by suppressing the production of inflammatory mediators.

• Nuclear Engineering and Technology
• /
• v.54 no.4
• /
• pp.1526-1533
• /
• 2022

Small modular reactors have garnered considerable attention in the recent years. Plate fuel elements exhibit a good application prospect in small modular pressurized water reactors for marine applications. Further, improved economic benefits can be achieved by extending the core lifetime of small modular reactors. However, it is necessary to realize a large initial residual reactivity for achieving a relatively long burnup depth finally. Thus, the selection of a suitable burnable poison (BP) is a crucial factor that should be considered in the design of small modular reactors. In this study, some candidate BPs are selected to realize the effective control of reactivity. The results show that ²³¹Pa₂O₃, ²⁴⁰Pu₂O₃, ¹⁶⁷Er₂O₃, PACS-J, and PACS-L are ideal candidates of BP, and since the characteristics of BP can increase the final burnup depth of assembly, the economic benefits are gained. Additionally, an optimal combination scheme of BPs is established. Specifically, it is proved that through a reasonable combination of BPs, a low reactivity fluctuation during the lifetime can be achieved, leading to a large final burnup depth.

• Asian-Australasian Journal of Animal Sciences
• /
• v.21 no.4
• /
• pp.582-589
• /
• 2008

This study attempted to determine effects of recombinant porcine epidermal growth factor (pEGF) and glutamine (Gln) supplement on the growth performance and intestinal development of piglets weaned at 14 days of age. A total of ninety-six piglets were allotted to one of four dietary treatments which comprised inclusion of 1.0 mg pEGF supernatant/kg diet or 0.5% Gln both alone and in combination. Each treatment consisted of four replicates with six pigs per pen for a 28 days experimental period. Two pigs per replicate were sacrificed and gastrointestinal tract samples were collected on day 14. Data showed that dietary treatment failed to promote growth performance. On day 14, diets supplemented with pEGF elevated pancreatic chymotrypsin, jejunal alkaline phosphatase, sucrase, lactase and maltase activities (p<0.05), but failed to alter the small intestinal villus morphology, DNA, or protein content of gastrointestinal mucosa. Diets supplemented with Gln increased pancreatic chymotrypsin activity, tended to enhance the protein contents of gastric (p = 0.08) and jejunal mucosa (p = 0.09) but did not influence the serum IgA level or the enzyme activity in the gastrointestinal tract. On day 28, the diets supplemented with Gln increasedt (p<0.05) serum IgA and the proliferation of peripheral blood mononuclear cells by PHA stimulation. However, a combination of pEGF and Gln did not have a synergistic effect on these biomarkers in early-weaned piglets. The results demonstrate that diets supplemented with recombinant pEGF supernatant indeed improve intestinal digestive enzyme activity and diets supplemented with Gln increases the immune response in early-weaned piglets.

• Journal of Korean Neurosurgical Society
• /
• v.58 no.3
• /
• pp.205-210
• /
• 2015

Objective : This study was aimed at optimizing the treatment of non-small-cell lung cancer (NSCLC) patients who are candidates for stereotactic radiosurgery (SRS) for brain metastases and harbor activating epithelial growth factor receptor (EGFR) mutations. Methods : We retrospectively reviewed the medical records from 2005 to 2010 of NSCLC patients with brain metastases harboring an activating EGFR mutation. Patients who received a combination therapy of SRS and EGFR-tyrosine kinase inhibitor (TKI) for brain metastases and those who received SRS without EGFR-TKI were compared. The primary endpoint was progression-free survival (PFS) of the brain metastases. Results : Thirty-one patients were eligible for enrolment in this study (SRS with TKI, 18; SRS without TKI, 13). Twenty-two patients (71.0%) were women and the median overall age was 56.0 years. PFS of brain lesions was not significantly prolonged in SRS with TKI treatment group than in SRS without TKI group (17.0 months vs. 9.0 months, p=0.45). Local tumor control rate was 83.3% in the combination therapy group, and 61.5% in the SRS monotherapy group (p=0.23). There were no severe adverse events related with treatment in both groups. Conclusions : Therapeutic outcome of concurrent SRS and TKI treatment was not superior to SRS monotherapy, however, there was no additive adverse events related with combined treatment.

• Development and Reproduction
• /
• v.20 no.4
• /
• pp.275-281
• /
• 2016

The purpose of this study was to investigate the improvement of growth in Israeli carp (Cyprinus carpio), and the cross experiment was carried out with two strains of Israeli carp. Four combinations of Israeli carp from Jeonbuk fisheries farm and Songpu mirror carp from Heilong Jiang, China (KK; Jeonbuk ♀ ${\times}$ Jeonbuk ♂, KC; Jeonbuk ♀ ${\times}$ China ♂, CC; China ♀ ${\times}$ China ♂ and CK; China ♀ ${\times}$ Jeonbuk ♂) were developed and reared. Body length, body weight and condition factor were determined at 20, 40, 60 and 170 days post-hatch (DPH). The results showed that there were differences in growth rate of the four groups. Body length of four groups were CK > CC > KC > KK and body weight were CC > CK > KC > KK at 170 DPH. The growth perfomance of four groups were statistically significant difference (P<0.05). During the rearing, CC group had longer length and higher weight at 170 DPH compared to other three groups and also condition factor was highest in the CC group, but there was no significant difference in a survival rate. These results indicated that the growth performance mainly depended upon brooder combination but survival rate could not significantly affect brooder.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.23 no.2
• /
• pp.196-207
• /
• 1999

The purpose of this study was to investigate the differences of the visual evaluation for the Picture image combination of Clothing and Ground. The major finding were as follows ; 1) For the visual evaluation of the Picture image as Clothing variation there were significant differences in all factors 2) For the visual evaluation of the Picture image as Ground variation there were significant differences in Attractiveness Hardness and softness Cuteness Attention Cool and Warm factor 3) For the visual evaluation of the Picture image as Percentage of Clothing there were significant differences in Attractiveness cool and Warm factor. It will Percentage of Clothing there were significant differences in Attractiveness Cool and Warm factor. It will aid in choosing the most beneficial background for any clothing brand. It will enhance the picture images to their full potential in any advertising medium 4) As a result of Regression analysis image effecting on " Preference" is refined-country like harmonious-inharmonious comfortable-uncomfortable beautiful-ugly splendid-dull stable-uneasy live-gentle 5) For the Image effecting on "Harmony" according to clothing image there were significant differences. the results analyzed according to the change of background are as follows. Mdern and strong images formed charming urban and cool visual images with urban and neat artificial backgrounds. Mature images were created with romantic and static artificial backgrounds. Mannish straight and conservative images created charming and rigid visual images in urban and formatted artificial background. Using a white natural background for the urban style created a cool visual image. The use of an interior background lead to warmer images and more defination lines Causal images created a rural and warm image which expressed charm and a soft visual while using a rural and natural background. A most unharmonious and hard image was created when using an urban and formatted artificial background. The coolest visual image was created with a cool and natural background. Feminine and flawless images created urban and neat visual image using an urban and formatted artificial background. The coolest visual image was fresh created with a cool and natural background. natural background.

• Journal of Korean Neurosurgical Society
• /
• v.60 no.4
• /
• pp.404-416
• /
• 2017

Objective : Functional and neural tissue recovery has been reported in many animal studies conducted with stem cells. However, the combined effect of cytokines and stem cells has not yet been adequately researched. Here, we analyzed the additive effects of granulocyte colony-stimulating factor (GCSF) on adipose-derived stem cells (ADSCs) infusion in the treatment of acute spinal cord injury (SCI) in rats. Methods : Four days after intrathecal infusion tubes implantation in Sprague-Dawley rats, SCI was induced with an infinite horizon impactor. In the Sham group (n=5), phosphate-buffered saline was injected 3, 7, and 14 days after SCI. GCSF, ADSCs, and ADSCs with GCSF were injected at the same time in the GCSF (n=8), ADSC (n=8), and ADSC+GCSF groups (n=7), respectively. Results : The ADSC and ADSC+GCSF groups, but not the GCSF group, showed significantly higher Basso-Beattie-Bresnahan scores than the Sham group during 8 weeks (p<0.01), but no significant difference between the ADSC and ADSC+GCSF groups. In the ladder rung test, all four groups were significantly different from each other, with the ADSC+GCSF group showing the best improvement (p<0.01). On immunofluorescent staining (GAP43, MAP2), western blotting (GAP43), and reverse transcription polymerase chain reaction (GAP43, nerve growth factor), the ADSC and ADSC+GCSF groups showed higher levels than the Sham and GCSF groups. Conclusion : Our analyses suggest that the combination of GCSF and ADSCs infusions in acute SCI in the rat does not have a significant additive effect. Hence, when combination agents for SCI stem cell therapy are considered, molecules other than GCSF, or modifications to the methodology, should be investigated.

• Nuclear Engineering and Technology
• /
• v.42 no.6
• /
• pp.680-689
• /
• 2010

The crack-tip stress fields and fracture mechanics assessment parameters for a surface crack, such as the elastic stress intensity factor or the elastic-plastic J-integral, can be affected significantly by the adjacent cracks. Such a crack interaction effect due to multiple cracks can alter the fracture mechanics assessment parameters significantly. There are many factors to be considered, for instance the relative distance between adjacent cracks, the crack shape, and the loading condition, to quantify the crack interaction effect on the fracture mechanics assessment parameters. Thus, the current assessment codes on crack interaction effects (crack combination rules), including ASME Sec. XI, BS7910, British Energy R6 and API 579-1/ASME FFS-1, provide different rules for combining multiple surface cracks into a single surface crack. The present paper investigates crack interaction effects by evaluating the elastic stress intensity factor and the elastic-plastic J-integral of adjacent in-plane surface cracks in a plate through detailed 3-dimensional elastic and elastic-plastic finite element analyses. The effects on the fracture mechanics assessment parameters of the geometric parameters, the relative distance between two cracks, and the crack shape are investigated systematically. As for the loading condition, an axial tension is considered. Based on the finite element results, the acceptability of the crack combination rules provided in the existing guidance was investigated, and the relevant recommendations on a crack interaction for in-plane surface cracks are discussed. The present results can be used to develop more concrete guidance on crack interaction effects for crack shape characterization to evaluate the integrity of defective components.

• Biomedical Science Letters
• /
• v.27 no.2
• /
• pp.51-58
• /
• 2021

Korean red ginseng (Panax ginseng Meyer) is a well-known traditional medicine, with numerous biological functions in the body. Portulaca oleracea (P. ole) belongs to the Portulacaceae family and has bioactive potential as a traditional medicine. This study aimed to determine the anti-inflammatory effects of Korean red ginseng extract (RGE) and P. ole extract on lipopolysaccharide (LPS)-treated RAW 264.7 cells. The combination of RGE (50 ㎍/mL) and P. ole (6.25 ㎍/mL) extracts significantly suppressed LPS-induced nitric oxide synthesis. The expression of proinflammatory mediators, including inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), and proinflammatory cytokines, including interleukin-1β, interleukin-6, and tumor necrosis factor-α, were markedly decreased by the combined treatment with RGE (50 ㎍/mL) and P. ole (6.25 ㎍/mL). Moreover, iNOS and COX-2 protein expression levels were also significantly reduced in the combined treatment compared to the LPS-stimulated group. In addition, the nuclear translocation of phosphorylated nuclear factor kappa-B was suppressed by the treatment with RGE and P. ole. Moreover, the mitogen-activated protein kinase pathway was also partially inhibited by the combination treatment with RGE and P. ole. Our results demonstrate that the treatment mixture with RGE and P. ole could be used as functional food and therapeutic herbal medicine in various inflammatory diseases.