• 제목/요약/키워드: column storage

검색결과 169건 처리시간 0.028초

탈지들깨박 Ethanol 추출물의 항산화 효과 (Studies on Antioxidant Activity of Ethanol Extracts from Defatted Perilla Flour)

  • 윤석권;김정한;김재욱
    • 한국식품과학회지
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    • 제25권2호
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    • pp.160-164
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    • 1993
  • The antioxidant activity of ethanol extracts from defatted perilla flour was investigated by measuring peroxide value of perilla oil during storage at $45^{\circ}C$. The antioxidant activity of ethanol extracts was also compared with BHA, BHT and tocopherol. Anti-oxidant activity of ethanol extracts was also examined in corn oil and lard. The ethanol extracts contents of defatted perilla flour and the original perilla seed were 7.69 and 4.56% respectively. The antioxidant activity of ethanol extracts was superior to that of 0.02% BHT, BHA and tocopherol in the perilla oil substrate, merely in concentration of one-twentieth as much as that contained in original perilla oil seeds. The fractions of non-polar solvent (hexane and chloroform) obtained from silicic acid column chromatography are less effective than that of polar solvent as an antioxidant. Antioxidant activity of partially purified ethanol fraction is slightly inferior to that of original crude ethanol extracts. Ethanol extracts were also effective in corn oil and lard almost same as in perilla oil. The total phenolic compound contents of crude ethanol extracts and partially purified ethanol fraction were 9.3, 6.4%, respectively.

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Simplified HPLC Method for the Determination of Prazosin in Human Plasma and Its Application to Single-dose Pharmacokinetics

  • Gwak, Hye-Sun;Chun, In-Koo
    • Biomolecules & Therapeutics
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    • 제13권2호
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    • pp.90-94
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    • 2005
  • Prazosin hydrochloride is an antihypertensive drug with selective ${\alpha}_1$-adrenoreceptor blocking effects. A simple high performance liquid chromatographic method has been developed and validated for the quantitative determination of prazosin in human plasma. A reversed-phase C18 column was used for the separation of prazosin and terazosin (internal standard) with a mobile phase composed of water, acetonitrile and triethylamine(75:25:0.1, V/V;pH5.0) at a flow rate of 1.5 ml/min. the fluorescence detector was set at excitation and emissionwavelengths of 250 and 370 nm, respectively. Intra-and inter-day precision and accuracy were acceptable for all quality control samples including the lower limit of quantification of 0.5 ng/ml. Good recovery (>80%) was seen in plasma. Prazosin was stable in human plasma under various storage conditions. This method was used successfully for a pharmacokinetic study in plasma after oral administration of a single 2-mg dose as prazosin base to 16 healthy volunteers. The maximum plasma concentration of prazosin was 23.1 ${\pm}$ 16.5 ng/ml at 2.1 h, and the mean area under the curve and elimination half-life were calculated to be 108.4 ${\pm}$ 74.2 ng ${\cdot}$hr/ml and 2.5 ${\pm}$ 0.6 h, respectively.

韓國 周邊 海洋 貯熱量의 秀節的 變動 (Seasonal Variation of Heat Content in the Neighbouring Seas of Korea)

  • 강용균
    • 한국해양학회지
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    • 제20권3호
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    • pp.1-5
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    • 1985
  • 한국주변 192개 정점 표층 300m의 15년간(1961~1975) 격월 수온자료를 사용하여 해양이 보유(방출)하는 영량의 계절적인 변동을 추정하였다. 동해에서는 100m 이내의 표층에서 계절적인 열의 보관과 방출이 일어나며, 수심이 얕은 서해와 남해에서는 거의 전 수심에 걸쳐서 계절적인 열보유량 변동의 연교차는 서해와 동해가 비슷하나, 열보유량 변동은 표면수온에 비하여 연주기 위상이 1내지 3개월 늦다. 해류와 계절풍에 의한 열이송으로 인하여 한국주변 해양 저열량의 시간적 변화의 연진폭은 태양복사에너지의 연진폭보다 훨씬 크다.

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HDTV용 고속 라인 메모리 회로 설계에 관한 연구 (A Study on the Design of High speed LIne Memory Circuit for HDTV)

  • 김대순;정우열;김태형;백덕수;김환용
    • 한국통신학회논문지
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    • 제17권5호
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    • pp.529-538
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    • 1992
  • 최근들어 HDTV를 위한 영상 신호처리 기술이 급속히 발전하고있다. 이러한 신호처리 기술의 향상에 따라 영상신호용 특수 기억소자의 개발이 요구되고 있다. 본 논문에서는 입력 스트로브로 부터 정보를 반아 기억하는 CMOS 플립플롭을 채용한 데이타 래치 방식과 HDTV 신호에 적합한 엑세스 시간을 얻기 위하여 새로운 읽기 방식이 고안 되었다. 기존의 쓰기 방식과 비교하여 데이터 래치 방식은 완전한 쓰기 동작을 위하여 비트라인 쓰기와 메모리셀 쓰기의 2개의 과정이 필요하고 같은 번지의 동시 입출력이 가능하다. 또한 스태틱 칼럼 모드를 응용한 읽기 방식과 분리된 읽기 워드라인을 채용하여 읽기 동작시 빠른 정보 감지가 가능하다.

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발사체 충격 방식을 사용한 초음속 액체 제트의 과도 분무 형상에 관한 연구 (Transient Spray Structures of Supersonic Liquid Jet Injected by Projectile Impact Systems)

  • 신정환;이인철;김희동;구자예
    • 한국분무공학회지
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    • 제17권2호
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    • pp.86-93
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    • 2012
  • The effects of projectile impact system on the transient spray characteristic which is supersonic liquid tip velocity were studied by experimentally. Supersonic liquid jets were generated by impact of a high speed projectile driven by a Two-stage light gas gun. A high speed camera and schlieren optical system were used to capture the spray structures of the supersonic liquid jets. In a case of nozzle assembly Type-A, expansion gases accelerate a projectile which has a mass of 6 grams from 250 m/s at the exit of the launch tube. Accelerated projectile collides with the liquid storage part, then supersonic liquid jets are injected with instantaneous spray tip velocity from 617.78 m/s to 982.54 m/s with various nozzle L/d. However, In a case of nozzle assembly Type-B which has a heavier projectile (60 grams) and lower impact velocity (182 m/s), an impact pressure was decreased. Thus the liquid jet injected at 210 m/s of the maximum velocity did not penetrate a shock wave and fast break-up was occurred. Pulsed injection of liquid column generated second shock wave and multiple shock wave.

실시간 내장형 응용을 위한 2차원 웨이브렛 변환 프로세서 (2D DWT Processor for Real-time Embedded Applications)

  • 정갑천;박성모
    • 전자공학회논문지CI
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    • 제40권2호
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    • pp.17-25
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    • 2003
  • 본 논문에서는 상태 변수 표현 방법에 따른 알고리즘 분할을 통해 2차원 웨이브렛 변환 연산을 실시간으로 처리할 수 있는 프로세서 구조를 제안하였다. 제안된 프로세서 구조는 영상입력에 대하여 행, 열 방향을 동시에 고려하여 데이터 플로우 방식으로 처리함으로써 중간적인 결과의 메모리 저장 및 읽기에 소요되는 전달 지연 시간을 감소할 수 있어 실시간 처리에 적합한 VLSI 구조이다. 필터의 길이를 K라할 때 프로세서는 내부에 4개의 곱셈기, 4개의 덧셈기 및 NK-N 크기의 메모리를 가지는 등의 하드웨어 복잡도가 낮아 웹 카메라 서버와 같은 내장형의 응용에 매우 적합한 구조이고, 쉽게 어레이 구조로 확장할 수 있어 고성능을 요구하는 다양한 영상 처리 응용에도 사용 가능하다.

간극공기압을 고려하는 불포화토의 유한요소해석 (Finite Element Analysis of Partially Saturated Soil Considering Pore-air Pressure)

  • 김재홍;황영철
    • 한국지반공학회논문집
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    • 제27권3호
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    • pp.95-102
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    • 2011
  • 불포화 지반을 이루고 있는 흙의 알갱이, 물과 공기의 연계해석이 전체 지반의 변형에 미치는 영향을 알아보고자, 흙 알갱이와 물의 두 가지 요소로 해석되어지는 기존 관점과의 차이를 분석하고 그에 대한 원인을 비교하였다. 열역학적 가정을 토대로 평형방정식을 이용하여 불포화토 거동을 지배하는 물과 공기의 흐름 관계를 유한요속해석을 위한 수학적인 알고리즘을 유도하여 배수시험 수치해석을 통해 기존 문헌과 비교 검증하였다. 3상으로 이루어진 불포화토 거동을 통해서 흙의 알갱이와 물과의 상호작용에서 공기압의 역할을 분석하여 불포화 지반 내에 물과 공기의 두가지 흐름에 대해 지반공학적인 적용성을 알아보았다.

Determination of trace icing Inhibitors (ether type) in free-floating fuels by gas chromatography-mass spectrometry

  • Shin, Ho-Sang;Ahn, Hye-Sil;Jung, Dong-Gyun
    • 한국지하수토양환경학회:학술대회논문집
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    • 한국지하수토양환경학회 2003년도 총회 및 춘계학술발표회
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    • pp.196-200
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    • 2003
  • A gas chromatography/mass spectrometric assay method was developed for the simultaneous determination of ethylene glycol monomethyl ether (EGME) and diethylene glycol monomethyl ether (DEGME) in spilled aviation fuels. Ethylene glycol monobutyl ether (EGBE) and ethylene glycol monoethyl ether (EGEE) were used as internal standard and surrogate, respectively. The sample preparation consists of back-extraction with 7 mL of methylene chloride after extraction of 50 mL of fuel with 2 mL of water. The extract was concentrated to dryness and dissolved with 100L of methanol and analyzed by CC-MS (SIM). The peaks had good chromatographic properties by using semi-polar column and the extraction of these compounds from fuel also gave high recoveries of 75 and 85 % with small variations for EGME and DEGME, respectively. Method detection limits were 1.3 ng/mL for EGME and 1.0 ng/mL for DEGME in spilled fuel. The method may be useful for fuel-type differentiation between kerosene and JP-8, which may originate from the storage tank.

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Simplified HPLC Method for the Determination of Mirtazapine in Human Plasma and Its Application to Single-dose Pharmacokinetics

  • Gwak Hye-Sun;Lee Na-Young;Chun In-Koo
    • Biomolecules & Therapeutics
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    • 제14권1호
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    • pp.40-44
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    • 2006
  • Mirtazapine is an antidepressant agent with dual action on both the noradrenergic and serotonergic neurotransmitter systems. A simple high performance liquid chromatographic method has been developed and validated for the quantitative determination of mirtazapine in human plasma. A reversed-phase Cl8 column was used for the determination of mirtazapine with a mobile phase composed of 0.01M ammonium acetate solution (pH 4.2) and acetonitrile (75:25, v/v%) at a flow rate of 1.2 mL/min. Terazosin hydrochloride was used as an internal standard. The fluorescence detector was set at excitation and emission wavelengths of 290 and 350 nm, respectively. Intra- and inter-day precision and accuracy were acceptable for all quality control samples including the lower limit of quantification of 3 ng/mL. Mirtazapine was stable in human plasma under various storage conditions. This method was used successfully for a pharmacokinetic study using plasma samples after oral administration of a single 30 mg dose as mirtazapine base to 8 healthy volunteers. The maximum plasma concentration of mirtazapine was $64.1{\pm}28.0ng/mL$ at 1.8 h, and the area under the curve and elimination half-life were calculated to be $674.1{\pm}218.5ng\;h/mL\;and\;23.4{\pm}3.8h$, respectively.

LNG냉열이용 BOG 재액화긍정 해석연구 (New reliquefaction system of Boil-Off-Gas by LNG cold energy)

  • 윤상국;최형식
    • Journal of Advanced Marine Engineering and Technology
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    • 제26권2호
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    • pp.256-263
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    • 2002
  • The Boil-Off-Gases(BOG) in the LNG production terminal are continuously generated during the unloading, storage and supply processes by the heat penetration. In order to use these gases as useful fuel, the reliquefaction process should be installed to put the reliquefied BOG in the main LNG supply line before the secondary pump in terminal. The current reliquefaction method of BOG in LNG terminal is the direct contact one between LNG and BOG in the absorption column. But the system has severe disadvantage, which is the 10 times of LNG circulation needed for unit mass of BOG reliquefaction. It causes, therefore, high power consumption of LNG circulation pump and excessive city-gas supply, even if short demand of NG is needed in the summer time. In this paper, the new reliquefaction system of BOG by using LNG cold energy with indirect contact in precooler was suggested and analysed. The result showed new indirect contact method of BOG reliquefaction system between LNG cold energy and BOG is much more effective than the current direct contact one because of only about 1.3 times of LNG circulation needed and higher energy saving by pump power reduction.