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Age-related Changes in Plasma Leptin from Early Growing to Late Finishing Stages of Castrated Holstein Steers: Utilizing Multi-species Leptin RIA

  • Vega, R.A.;Lee, H.G.;Kuwayama, H.;Matsunaga, N.;Hidari, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.5
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    • pp.725-731
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    • 2002
  • This experiment was performed to understand the changes in plasma leptin in association with plasma IGF-1, body weight and ADG from early growing to late finishing stages of Holstein steers. Blood collection was performed by arterial vein puncture at selected monthly ages of 1 (54 kg), 2.6 (103 kg), 7.2 (205 kg), 13.5 (314 kg), 16.9 (414 kg), 22.2 (550 kg), 24.9 (626 kg) and 27.4 months (695 kg). The blood was analyzed for leptin using the multi-species leptin RIA with recombinant bovine leptin (rbleptin) as standard, plasma IGF-1 was also measured using RIA. Against the standard rbleptin, the multi-species Leptin RIA system's sensitivity, cross reactivity, slope and recovery of 41.0 ng/ml rbleptin in plasma were 4.9 ng/ml, 11.22%, -1.396 and 97.8%, respectively. Plasma leptin measured were more than 5.0 ng/ml, which enable multi-species RIA system to investigate plasma leptin in normal growing steers. Body weight resulted to a highly significant second-degree polynomial relationship with plasma leptin (q=0.54, p<0.0001) and plasma IGF-1 (q=0.44, p<0.0001) from 1 to 27.4 monthly ages. However, the second-degree polynomial curve of plasma leptin and IGF-1 differs showing a concave and convex curvilinear relationship, respectively. ADG was not significantly associated to plasma leptin (r=0.06, p>0.05) and plasma IGF=1 (r=0.06, p>0.05) from 1 to 27.4 monthly ages. Low coefficient, but significant associated increase of plasma leptin and IGF-1 (r=0.12, p<0.008) from 1 to 27.4 months was observed. The uncoordinated increases of plasma IGF-1 at growing and plasma leptin at fattening period, may indicate (1) indirect involvement of endogenous IGF-1 on leptin secretion, and (2) IGF-1 level may signify lean and bone accretion while plasma leptin may mirror body fatness across the monthly ages of Holstein steers.

The Nutritional Value of Brown Rice and Maize for Growing Pigs

  • Li, X.L.;Yuan, S.L.;Piao, X.S.;Lai, C.H.;Zang, J.J.;Ding, Y.H.;Han, L.J.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.6
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    • pp.892-897
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    • 2006
  • An experiment was designed to study the nutritional value of Chinese brown rice and maize for growing pigs. Six male grower pigs (Duroc${\times}$Landrace${\times}$Large White, $24.3{\pm}1.26$ kg average initial BW) were surgically fitted with a simple T-cannula at the terminal ileum and allotted within a $2{\times}2$ Latin square design. The pigs were fed either a maize or brown rice diet in a direct method to determine their digestibility. The brown rice used in this experiment was husked from one kind of early, long grain, and non-glutinous rice (ELGNR, indica rice: non-waxy rice, containing amylopectin and amylose) in southern China. Chromic oxide was used as a marker. The diets were supplied at about 4.0% of body weight in dry matter/d. Total faeces and urine were collected on days 4 and 5; digesta was collected on days 6-8 in each period. The average body weight was 24.3 kg at the start of the experiment and 27.6 kg at the end. The results showed that the apparent ileal digestibilities of most amino acids of brown rice were significantly higher than those in maize (p<0.01), as were the apparent ileal digestibilities of crude protein (CP), digestible energy (DE), organic matter (OM) and dry matter (DM) (p<0.05). However, the apparent ileal starch digestibilities of the two treatments were similar (p>0.05). The values of the apparent faecal digestibilities derived from the two methods, marker and total faecal-collection methods, were very similar and also correlated with each other. The difference in absolute value of the apparent faecal digestibilities between brown rice and maize was smaller compared to that of the apparent ileal digestibilities. The net protein utilization was higher (p = 0.07) and the DE metabolizable rate was significantly higher (p<0.01) for brown rice than for maize. The metabolizable energy (ME) of brown rice is similar to that of maize, while the DE of brown rice was relatively lower. It can be concluded that Chinese brown rice are better than maize not only in apparent ileal digestibilities, but also in metabolizable rate of amino acids and gross energy under the present study conditions.

Effects of Job Stress, Fatigue, Burnout, and Job Satisfaction on Turnover Intention among General Hospital Nurses (종합병원 간호사들의 직무스트레스, 피로, 소진 및 직무만족도가 이직의도에 미치는 영향)

  • Lim, Yeon-Hee;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.264-274
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    • 2018
  • This study constructed a prediction model based on covariance structure to identify the causal relationship between job stress, fatigue, burnout, and job satisfaction on turnover intention in nurses working in general hospitals. The study subjects were 648 nurses at a general hospital in D city. Data collection was surveyed by using self-administered questionnaires structured during the period from November 1, 2016 to December 31, 2016. As a result, the level of turnover intention was significantly higher in the group showing higher job stress, fatigue, and burnout and significantly higher in the group showing lower job satisfaction. The turnover intention of subjects showed a significant positive correlation with job stress, fatigue, and burnout but showed a negative correlation with job satisfaction. As a result of covariance structure analysis, job stress had greater influence on turnover intention than fatigue, burnout, and job satisfaction. Higher job stress, fatigue, and burnout and lower job satisfaction were associated with increased turnover intention. The results of this study show that the turnover intention of general hospital nurses is significantly related to job stress, fatigue, burnout, and job satisfaction. In particular, job stress had a greater effect on turnover than fatigue, burnout, and job satisfaction. Therefore, in order to lower the turnover intention of general hospital nurses, it is necessary to seek ways to mitigate job stress.

Development of a Tool to Measure Suffering in Patients with Cancer (암환자의 고통 측정도구 개발에 관한 연구)

  • 강경아
    • Journal of Korean Academy of Nursing
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    • v.29 no.6
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    • pp.1365-1378
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    • 1999
  • This study is a methodological research study to develop an instrument to measure in patients with cancer and to test the validity and reliability of the instrument. The research procedure was as follows : 1) The first step was to develop conceptual framework based on a comprehensive review of the literature and in-depth interviews with patients with cancer. This conceptual framework was organized in to three dimensions (the intrapersonal dimension, the significant-other and context related dimension, the transcendental dimension). Initially 59 items were adopted. 2) These items were analyzed through the index of content validity(CVI) and 53 items were selected which met more than 80% on the CVI. 3) The pretest was carried out with 87 patients with cancer. After the pretest results were analyzed by item analysis, 44 items were selected. A second test of content validity was conducted and 6 items were eliminated considering the 80% CVI. 4) To test for reliability and validity, data collection was done during the period from January 25, 1999, to February 26, 1999. The subjects for the test were 160 patients with cancer and 185 healthy persons. analysis, item analysis and multitrait-multimethod method to analyze validity. The findings are as follows : 1) The Cronbach's alpha coefficient for internal consistency was .92 for the total 38 items and .79, .82, .85, for the three dimensions in that order. 2) The item analysis was based on the corrected item to total correlation coefficient( .30 or more) and information about the alpha estimate if this item was dropped from the scale. 3) As a result of the initial factor analysis using principal component analysis and varimax rotation, one item was deleted because of factor complexity (indiscriminate factor loadings). In the secondary factor analysis, 7 factors with eigenvalue of more than 1.0 were extracted and these factors explained 56 percents of the total variance. The seven factors were labeled as 'family relationship', 'emotional condition', 'physical discomfort', 'meaning and goal of life', 'contextual stimuli', 'change of body image', 'guilt feelings'. 4) The convergence effect between this instrument and the life satisfaction scale was identified and there was significant positive correlation(r= .52, p= .00). The discriminant validity between this instrument and the depression scale(CES-D) was tested and there was significant negative correlation(r= -.50, p= .00). The instrument for accessing the suffering of patients with cancer developed in this study was identified as a tool with a high degree of reliability and validity. In this sense, this tool can be effectively utilized for assessment in caring for patients with cancer.

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A Study of the Lived Experiences of Clients Receiving Long-Term Hemodialysis (장기 혈액투석 수혜자들의 생활경험에 관한 연구)

  • 신미자
    • Journal of Korean Academy of Nursing
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    • v.27 no.2
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    • pp.444-453
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    • 1997
  • The purpose of this study was to construct a grounded theory as the basis for nursing intervention by describing and analysing the holistic lived experiences of clients receiving long-term hemodialysis. The subjects of this study were fifteen persons receiving regular hemodialysis regimen at artificial kindey treatment centers in two different university hospitals, and who were able to participate in conversation and were available for long and dup interviews. Eight of the subjects were male and seven were female and their ages ranged from 30's to 60's. The length of the hemodialysis experience ranged from two months to six years. The collection and analysis of data were done in accordance with the grounded theory methodology of Strauss & Corbin. The method to collect the data mainly depended. on long and deep interviews, participant observation and focused group interviews and the equipment used to collect data were a portable tape recorder and field notes. The study is summarized as follows : 1. The meaning of holistic lived experiences of clients receiving long -term hemodialysis was found to be uncertainty. which was identified as the core category. 2. The main categories following the core category were found to be shock, ambiguity, social support and quality of life. 3. Through the main category the type of behavior newly formed by clients receiving long-term hemodialysis was found to be as follows. That is to say, in the circumstances of shock caused by the identified fact and the ambiguity of hemodilysis they formed a quality of life based on social support, which was found to be a kind of chaotic phenomenon. 4. The lived experiences of clients receiving long-tern hemodialysis was found to include nine categories : emotional shock, feelings of isolation, burden, unclearness, dependency, help from others, coping strategies, maintenance of self-esteem and transitional life. 5. The intervening factors influencing each category are as follows : 1) The factors influencing 'emetional shock' were found to be set age, the level of knowledge received in advance, locus of control, the period of struggle against the disease before hemodialysis and whether any serious illness existed. 2) The factors influencing 'feelings of isolation' were found to be religion and the length of the hemodialysis experience. 3) The factors influencing 'burden' were found to be sex, economic situation, employment status and the length of the hemodialysis experience. 4) The factors influencing 'unclearness' were found to be sex, age, religion. economic situation, the length of the hemodiaysis experience, whether they had had a transfusion and whether there were any complications. 5) The factors influencing 'help from others' were found to be religion. economic situation, past experiences and whether family members lived together. 6) The factors influencing 'coping strategies' were foung to be age, level of education, experiences of illness and locus of control. 7) The factors influeruing 'maintenance of self-esteem' were found to be the length of the hemodialysis experience and self-actualization. 8) The factors influencing 'transitional life' were found to be age, religion, economic situation, employment status. locus of control. past experiences and whether there was a plan for a kidney transplant.

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Scientific Conservation Treatment of Artifacts Collected from the Lime-soil Mixture Barrier Tombs Excavated from the Site of a Public Residential Area in Godeung-dong, Seongnam (성남 고등 공공주택지구 출토 회격묘 과학적 보존처리)

  • Kim, Woungshin;Jeon, Juyeon;Kim, Beomjun;Han, Minsoo;Lee, Minhye
    • Conservation Science in Museum
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    • v.22
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    • pp.53-68
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    • 2019
  • Two lime-soil mixture barrier tombs were excavated from the tomb complex of the Woo Family of the Danyang Wu clan dating to the Joseon dynasty in Godeung-dong, Seongnam-si, Gyeonggi-do. Relevant records offer information for more precisely dating these tombs and identifying their occupants. Tomb No. 4, in which a married couple was interred, has a corbeled square ceiling and inscriptions and paintings on its outer walls. The conservation treatment and an infrared inspection revealed that they were intended to express mourning. Tomb No. 6 has a corbeled rectangular ceiling and a single individual interred within. As the basic structure of the tomb was partially damaged in the process of disassembling it while moving the burial site, it was planned to exhibit the tomb outdoors after the remains and relics are collected. However, as the conservation treatment revealed the presence of funeral fans and pitch, and since the remaining structure clearly demonstrates the features of lime-soil mixture barrier tombs from the Joseon dynasty, the plan was changed following a meeting of an advisory council that decided in favor of presenting the tomb indoors. According to the analysis, the pitch is assumed to be resin of a rather low purity due to the immixture of foreign substances. The two tombs are expected to serve as important materials for related research, such as changes by period in the forms of Joseon-era tombs.

A Study of Moral Judgment and Ethical Decision Making and Ethical Dilemmas Experienced in Practice by Nursing Students (간호대학생의 도덕판단력과 윤리적 의사결정 및 실습에서 경험한 윤리적 딜레마)

  • Noh, Yoon Goo;Jung, Myun Sook
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.6
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    • pp.2915-2925
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    • 2013
  • This study examined the moral judgments and ethical decision-making and analyzed ethical dilemmas experienced in practice by nursing students. The data were collected using self-reported questionnaires and reports from 189 college students in their 2nd ~ 4th grades. Data collection period was from Nov 6th - 20th in 2012. Each grade's P(%) scores were 47.92, 43.74, and 43.75 respectively.. For stage 4 score, each grade's scores were 22.37, 22.98, and 19.74. This result shows that, compared to juniors, senior student's P(%) scores did not drop and stage 4 scores rather decreased, which is in line with the results of previous studies about the effects of ethics education. This finding could be attributed to the regular and voluntary case presentations and discussions required for the senior participants. Regarding ethical decision-making type, the most favored was type 3(35.45%). Among seven categories of the ethical dilemmas facing the students, the most commonly reported was the patient's rights and dignity, followed by practices based on nursing standards, arranging for dying patients. This study raises the need that the curriculum is revised to encourage student's participation in the analysis of ethical issues they confront in the field.

Influences of Emotional Labor, Hardiness on Job Satisfaction of Nurses in Comprehensive Nursing Care Service Units (간호·간병통합서비스 병동 간호사의 감정노동, 강인성이 직무만족도에 미치는 영향)

  • Lim, Hye-Sook;Song, Eun Ju
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.4
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    • pp.65-72
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    • 2020
  • The purpose of this descriptive research study was to identify the effects on job satisfaction of nurses working at comprehensive nursing care service units. The study was conducted in five hospitals, two of 250 beds or more in three cities and three of 800 beds. The study subjects were nurses working at comprehensive nursing care service units. A structured questionnaire of 150 questions was distributed to them and 146 were collected. The data collection period was from August 1, 2019 to November 15, 2019. The collected data were analyzed using the SPSS 22.0 program, using x2-test, t-test, ANOVA, Pearson correlation, and multiple linear regression. Emotional labor and toughness were negatively correlated (r=-.20, p=.018), and emotional labor and job satisfaction were positively correlated (r=.25, p=.004). The predictive variables affecting the job satisfaction of the subjects were the aptitude of the ward service (β=-.35, p=<.001) and hardness(β=.21, p=.009). The explanation of job satisfaction in the variables was 18.2% (F=3.54, p=.009). The study results revealed that the predictive variables affecting job satisfaction were the hardiness and aptitude of the ward service. Therefore, in order to increase the job satisfaction of ward nurses, it is necessary to provide administrative support to control the hardiness of the nurse and to allocate manpower in consideration of the aptitude in the hospital personnel system.

Changes in Rural Health and Environmental Factors (2001-2010) A Comparison between Agricultural and Nonagricultural Groups (농촌 환경ㆍ건강 지표의 변화 추이(2001~2010년) -농촌 거주 농업종사자와 비농업종사자의 비교-)

  • Rhie, Seung Gyo;Hwang, Jeong-Im;Won, Hyang Rye
    • The Korean Journal of Community Living Science
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    • v.25 no.1
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    • pp.99-111
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    • 2014
  • To verify welfare needs, rural health and environmental factors were compared between agricultural and nonagricultural groups over the past 10 years. Based on a survey of rural life by the Rural Development Administration, whose sample included agricultural (72.8%) and nonagricultural (27.2%) groups, all factors were analyzed using SAS ( 9.3). For rural home heating, the use of oil boilers (77.2%-78.0%) decreased (53.0%-53.7%) over the same period, whereas that of electric boilers increased (21.9% and 13.5% for agricultural and nonagricultural groups, respectively). The joint water- supply increased, and the use of flush toilets (52.4% to 84.5% in the agricultural group and 64.6% to 81.4% in the nonagricultural group) and hot-water bathing was higher in the agricultural group (79% to 92.6%) than in the nonagricultural group (72.2% to 87.6%) at the p<0.001 level. Incineration accounted for the largest portion of household waste until 2006, when it was replaced by other treatment methods such as the pay-per-treatment option (44.4% and 68.3% in the agricultural and nonagricultural groups, respectively) (p<0.001). Garbage disposal in 2001 was mainly burial or animal feed, but separate collection increased in 2010 (42.2% and 64.3% in the agricultural and nonagricultural groups, respectively) (p<0.001). The self-perception of health was lower in the agricultural group than in the nonagricultural group (2.96 to 2.74 on a five-point scale in the agricultural group and 3.07 to 2.98 in the nonagricultural group). Drinking decreased less in the agricultural group (criteria: one point once a week,; 1.48 to 1.20) than in the nonagricultural group (1.13 to 0.80) at p<0.001, and a similar pattern was found for smoking (p<0.001). Health screening decreased in the last 10 years (scoring based one point/1-2 times per year,: 0.94 to 0.64 in the agricultural group and 1.08 to 0.69 in the nonagricultural group;p<0.01). These results indicate that various health and environmental factors were less favorable to farmers except for bathing in comparison to nonagricultural living in the same area. This suggests that people in agriculture are less likely to live and work in favorable environments than those outside the sector and thus indicates a need for more attention to the national health welfare system for farmers for systematic realization.

The Effect of Congruency between User Participation and Producer Response on User Generated Content (컨텐츠 유통 플랫폼에서 이용자 참여와 생산자 반응의 적합성 효과에 관한 연구)

  • Son, Jung-Min;Lee, Jun-Seop
    • Journal of Distribution Science
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    • v.13 no.8
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    • pp.73-80
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    • 2015
  • Purpose - This study's objective is to analyze the content of the communications between users and producers based on the construal level theory. User generated content refers to content created in an online-based service where users and producers communicate interactively with each other. In a user generated content platform, the messages sent and received between the many players, the users and producers who use the content, may be analyzed at the psychological level based on construal level theory. Research design, data, and methodology - This study gathered user and producer participation through a snow-bowling sampling method. The data analyzed includes 125 video clips and 2,912 comments. The period of the data collection was from September 2014 to December 2014. The collected data was analyzed using a t-test and two-way ANOVA. Results - This study obtained the following research results. First, users who were a short social distance from producers responded to user participatory activities stated in concrete language rather than abstract language. In contrast, users who were at a longer social distance from producers tended to respond to the content requesting user participation through abstract language. Second, if users and producers were at a short social distance from each other, user preference increased more when a producer response to user participation was expressed concretely rather than when it was expressed abstractly. In contrast, if the users were at a longer social distance, users' preferences increased more when producer response was expressed abstractly rather than when it was expressed concretely. Conclusion - This study found that the effect of suitability, in which the social distance and the content were in congruence at the construal level, could be observed. Therefore, based on this, academic and practical implications were drawn. The three main insights of the study are as follows. First, firms can use psychological factors to analyze the message content of users in their distribution platforms. This study reveals managerial implications for marketing managers who want to take make use of this analysis of user and producer communications. This study indicates that the main factors include the concrete and abstract scores and social distance between users and producers. Second, we also provide the strategic guidelines to maximizing user preferences and other outcomes. The main dependent variable in this study is the user preference shift; the variable increases through the congruence effect; and the construal level is determined by the social distance between the users and producers and the type of producer response. The outcomes here from users can be utilized to develop several systemic strategies. One process to use the outcomes could be: (1) firms could measure the users and producers social distance; (2) calculate the concreteness or abstractness of the messages; and, (3) predict the user preference outcomes by the congruence between user and producer social distance and the abstractness or concreteness of the message content.