• Title/Summary/Keyword: cognitive disorder

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A Study on Brain Disease Research Trends and Need to Conduct Mechanism Studies on Temporomandibular Joint Disorder Related Cerebrovascular Diseases (뇌질환 연구 동향 조사 및 턱관절 장애 관련 뇌질환 기전 연구의 필요성)

  • Lee, Se-Eun;Lee, Min Ji;Lee, Byoungho;Lim, Sehyun;Cho, Suin
    • Journal of TMJ Balancing Medicine
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    • v.8 no.1
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    • pp.11-15
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    • 2018
  • Recently, clinical efficacies of the intraoral balancing appliance therapy have been reported by several researchers, and it has been found that there are various kinds of diseases that can be effectively applied. However, studies on cerebrovascular disease, one of the main diseases with a high mortality rate, are still poorly reported, and studies of temporomandibular joint disorder (TMD)-induced changes in brain function suggest that cerebrovascular disease is more appropriate as an adaptive disorder of the temporomandibular joint (TMJ) balancing device. In the developed countries, the importance of research on the structure and function of the brain has been recognized and spurred on the related research. In Korea, the research on brain function and cognitive disorders should have promoted more massively. In order to regain its former reputation in the Korean medicine in the field of cerebrovascular disease, it should be spurred on basic research and clinical case studies. In addition, extensive and in-depth studies including animal studies are needed to establish the basis of underlying mechanisms of the TMJ balancing therapies.

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The Role of Quantitative Electroencephalogram in the Diagnosis and Subgrouping of Attention-Deficit/Hyperactivity Disorder

  • Bong, Su Hyun;Kim, Jun Won
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.32 no.3
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    • pp.85-92
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    • 2021
  • Attention-deficit/hyperactivity disorder (ADHD) leads to functional decline in academic performance, interpersonal relationships, and development in school-aged children. Early diagnosis and appropriate intervention can significantly reduce the functional decline caused by ADHD. Currently, there is no established biological marker for ADHD. Some studies have suggested that various indicators from the quantitative electroencephalogram (QEEG) may be useful biological markers for the diagnosis of ADHD. Until the 2010s, theta/beta ratio (TBR) was a biomarker candidate for ADHD that consistently showed high diagnostic value. However, limitations of TBR have recently been reported. Studies have demonstrated that phase-amplitude coupling, especially theta phase-gamma amplitude coupling, are related to cognitive dysfunction and may assist in the diagnosis of ADHD. As yet, the underlying mechanism is not clearly established, and the clinical efficacy of these biomarkers needs to be proven through well-controlled studies. Based on the heterogeneous characteristics of ADHD, subgrouping through QEEG plays a key role in diagnosis and treatment planning. Sophisticated, well-designed studies and meta-analyses are necessary to confirm these findings.

Association of the Comprehensive Attention Test and the Korean Wechsler Intelligence Scale for Children-Fourth Edition in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder

  • Min-Su Jang;Sang-Keun Chung;Jong-Chul Yang;Jong-Il Park;Joo-Han Kwon;Tae-Won Park
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.34 no.3
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    • pp.181-187
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    • 2023
  • Objectives: This study aimed to investigate the correlation between the Comprehensive Attention Test, Korean-Wechsler Intelligence Scale for Children-Fourth Edition, and Attention-Deficit/Hyperactivity Disorder (ADHD) Rating Scale-IV scores in children and adolescents with ADHD. Methods: Fifty-five children and adolescents diagnosed with ADHD and not taking psychiatric medications were included in this retrospective study. A correlation analysis was performed. Results: Although simple visual and auditory selective attention have diagnostic value in traditional continuous performance tests, this study revealed that inhibition-sustained attention and interference-selective attention are also effective in evaluating ADHD. Furthermore, the correlation between the attention and intelligence test scores varied depending on the use of visual or auditory stimuli. Conclusion: The findings of this study contribute to clarifying our understanding of the cognitive characteristics of children and adolescents with ADHD and can be used in future research.

COGNITIVE CHARACTERISTICS OF CHILDREN WITH DYSLEXIA AND/OR ATTENTION DEFICIT/HYPERACTIVITY DISORDER (읽기 장애 아동과 주의력 결핍/과잉 활동장애 아동의 인지적 특성)

  • Kim, Seung-Tai;Kim, Ji-Hae
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.7 no.2
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    • pp.224-232
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    • 1996
  • The present study was conducted to investigate cognitive characteristics of children with dyslexia and/or attention deficit/hyperacidity disorder. Cognitive characteristics were evaluated by using KEDI-WISC, the Basic Achievement Test, TOVA, MFFT, and neuropsychological tests. ADHD group showed significantly lower level of performance in response time for correct responses and presented variability for correct responses in TOVA. Dyslexia and mixed group showed lower performance in Reading I and Reading II, Writing subtest in the Basic Achievement Test than those of ADHD group and in Information subtest of KEDI-WfSC. In order rd determine the diagnostic effectiveness of each psychological tests, discriminant analysis was conducted. In this analysis, 11 subtests of KEDI-WISC and 4 variables of TOVA, 4 subtests of the Basic Achievement Test, and MFFT, WCST were included as independent variables and each diagnostic roups were dependent variables. Discriminant analysis indicated that overall percentage of correct classification was 93.88%. The clinical implifications and limitations of the present study were listed and discussed.

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The awareness and coping of human suffering in the "PTSD era": Searching for an alternative paradigm of trauma recovery ('PTSD 시대'의 고통 인식과 대응: 외상 회복의 대안 패러다임 모색)

  • Choi, Hyunjung
    • Korean Journal of Cognitive Science
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    • v.26 no.2
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    • pp.167-207
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    • 2015
  • This study focused on the awareness and coping methods of psychological trauma and human suffering in the contemporary era after the development of posttraumatic stress disorder(PTSD) including the situations in the Korean society, and proposed principles for an alternative paradigm of trauma recovery. Trauma is defined as an 'external' stress causing chronic suffering mediated by memory, and the American Psychiatric Association approved PTSD in the Diagnostic and Statistical Manual of Mental Disorders in 1980. The development of PTSD empowered moral legitimacy to the victims, opened a successful way to treatment, and accomplished explosive amount of research in the area of neurobiology and cognitive neuroscience. However, this also narrowed the understanding of human suffering, and the importance of an alternative coping method which overcomes the limitations of technical intervention became overlooked. Moreover, the Korean society has an underlying mechanism of replacing the matter of trauma to a problem of an individual. This is shown among the historical context of splitting and denial, and among medicalized bureaucracy. Trauma should be acknowledged as a social suffering, and searching for an alternative paradigm is in need. This study suggested the following principles; seeking for truth and justice, survivor as the agent of recovery emphasizing the responsibility of the community, ecological adaptations of recent bio-psychological achievements, and finally putting emphasis on continuous discussions about the definition of recovery.

The Comparison of Intelligence Efficacy According to Methylphenidate Administration in Attention Deficit Hyperactivity Disorder Patients (주의력결핍 과잉행동장애 환자의 약물치료에 따른 지적효율성의 변화)

  • Park, Hyung-Bae;Bai, Dae-Seok;Ha, Jeong-Sang;Seo, Wan-Seok;Song, Chang-Jin
    • Journal of Yeungnam Medical Science
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    • v.18 no.2
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    • pp.253-266
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    • 2001
  • Background: The causes of ADHD(attention deficit hyperactivity disorder) are various, so it is impossible to understand the whole characteristics of ADHD, only with simple intelligence testing scales. We compared cognitive characteristics of ADHD group with normal controls with Korean Kaufman Assessment Battery for Children(K-ABC). It is well known to evaluate neuropsychological and cognitive aspects of the children. Materials and Methods: Age and sex matched 40 ADHD patients and 40 normal controls tested with the K-ABC. Each subscales compared between pre-treatment patients and controls, pre-treatment and post-treatment in patient group, post-treatment patients and controls. Results: Significant differences are observed in sequential processing, simultaneous processing, cognitive processing and achievement between pre-treatment patients and controls, and in gestalt closure between pre-treatment and post-treatment patients group. But there are no significant differences between pre-treatment patients and controls in gestalt closure and reading/decoding. Conclusions: Methylphenidate improved the scores of simultaneous scale, which means improvement of executive functions such as divided attention, analysis and organization. Methylphenidate also reduced distractibility.

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Comparison of the Effects of Cognitive Behavioral Therapy and Behavioral Treatment on Obesity Treatment by Patient Subtypes: A Systematic Review and Meta-analysis (비만치료에 있어서 환자특성에 따른 인지행동요법과 행동수정요법의 효과 비교: 체계적 문헌고찰 및 메타분석)

  • Cha, Jin-Young;Kim, Seo-Young;Shin, In-Soo;Park, Young-Bae;Lim, Young-Woo
    • Journal of Korean Medicine for Obesity Research
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    • v.20 no.2
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    • pp.178-192
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    • 2020
  • Objectives: The present study aimed to compare the impacts of cognitive behavioral therapy (CBT) and behavioral treatment (BT) on weight loss and psychological outcomes among patients with three different subtypes of obesity: simple obesity, obesity with binge eating disorder, and obesity with depression. Methods: Embase, PubMed, the Cochrane Central Register of Controlled Trials, Research Information Sharing Service, and Korean Studies Information Service System were systematically searched for randomized controlled trials conducted on or before May 2020, that used CBT to treat obesity. Methodological quality was assessed using Cochrane's risk of bias tool 2 and publication bias was evaluated through the funnel plot using the trim and fill method, Egger's test, and Begg and Mazumdar rank correlation test. A meta-analysis was conducted using a random-effects model and the standardized mean difference with 95% confidence interval (CI) was used to determine effect size. Results: Twenty-one randomized controlled trials with a total of 22 intervention arms and 2,590 patients were included. Our study results revealed that the effects of CBT, compared with BT, on weight loss distinctly differed across all patient subgroups. In the simple obesity group, CBT was more effective than BT (Hedges' g=0.138, CI=0.012~0.264); however, in the obesity with binge eating disorder group, BT was more effective than CBT (Hedges' g=-0.228, CI=-0.418~-0.038); in the obesity with depression group, the effect of CBT was not statistically different from that of BT (Hedges' g=0.276, CI=-0.307~0.859). Further studies with larger sample sizes are required to confirm the outcomes observed in this study. Conclusions: Our results indicated that the effects of CBT on obesity treatment vary based on patient subtype. Therefore, our findings suggest that CBT or BT should be selectively recommended as a treatment strategy for different obesity subtypes.

A Systematic Review of Programs for Post-traumatic Stress Disorder Patients in South Korea (외상 후 스트레스 장애 환자를 위한 국내 프로그램 체계적 고찰)

  • Ik-Sung KIM;Eun-Sol JU
    • The Journal of Economics, Marketing and Management
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    • v.12 no.1
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    • pp.97-104
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    • 2024
  • Purpose: This study attempted to systematically review the programs of patients with post-traumatic stress disorder in South Korea over the past decade, identify specific methods and effects, and present program guidance guidelines through them. Research design, data and methodology: This study is a systematic literature review, and studies registered in the RISS, NDSL, DBpia, and KmBASE search databases from January 1, 2013 to August 31, 2023 were targeted. Keywords were 'post-traumatic stress disorder', 'program' or 'treatment'. A total of 2,324 documents were searched, and 237 duplicate papers were excluded. After that, the title and abstract were viewed, and 2,058 papers that did not meet the inclusion criteria and exclusion criteria were excluded. In addition, the full text was checked and the final 11 documents were analyzed excluding 18 documents. Results: Among the 11 literatures, 45.45% of randomized control studies and 54.54% of non-randomized control studies were found. As for gender, 41.18% of women, 28.64% of 30-39 years old, and 34.27% of trauma causes were industrial accidents. Programs for patients with post-traumatic stress disorder were classified into art therapy, cognitive behavior therapy, and mindfulness programs, and art therapy was the most used at 45.45%. The sessions of the program were widely applied at 45.45% for 10 sessions and 36.36% for 60 minutes per session. Conclusions: This study has a limitation in that it only analyzed domestic intervention programs within 10 years. However, this study is meaningful in that it is intended to present program guidance guidelines through reviewing domestic programs for post-traumatic stress patients. In the future, it is necessary to conduct research such as expanding the scope of literature review at home and abroad.

Neuroglial Cells : An Overview of Their Physiological Roles and Abnormalities in Mental Disorders (신경아교세포의 정상 기능과 정신장애에서 나타나는 신경아교세포 이상에 대한 고찰)

  • Lee, Kyungmin
    • Korean Journal of Biological Psychiatry
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    • v.22 no.2
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    • pp.29-33
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    • 2015
  • The brain maintains homeostasis and normal microenvironment through dynamic interactions of neurons and neuroglial cells to perform the proper information processing and normal cognitive functions. Recent post-mortem investigations and animal model studies demonstrated that the various brain areas such as cerebral cortex, hippocampus and amygdala have abnormalities in neuroglial numbers and functions in subjects with mental illnesses including schizophrenia, dementia and mood disorders like major depression and bipolar disorder. These findings highlight the putative role and involvement of neuroglial cells in mental disorders. Herein I discuss the physiological roles of neuroglial cells such as astrocytes, oligodendrocytes, and microglia in maintaining normal brain functions and their abnormalities in relation to mental disorders. Finally, all these findings could serve as a useful starting point for potential therapeutic concept and drug development to cure unnatural behaviors and abnormal cognitive functions observed in mental disorders.

Effect of Cognitive behavior therapy program in child with Posttraumatic Stress Disorde (인지행동치료 프로그램이 외상 후 스트레스장애(PTSD) 아동에 미치는 효과 - 학교폭력 피해아동을 중심으로 -)

  • Lee Jin-Suk;Han Young-Suk
    • Korean Journal of Human Ecology
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    • v.9 no.2
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    • pp.21-31
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    • 2006
  • The purpose of this study is to investigate the differences in irrational faith and the school adaptation of elementary school students by experimental group and control group. To achieve these goals, the followings are setting the programs. The subjects are selected from grade 4, 5, 6 students from the elementary schools. The tools used for this study were Irrational faith Test and School adaptation Test. The followings are the results of the analysis of the collected data. First, in the analysis of irrational faith, there is no significant difference between experimental group and control group. Second, in the analysis of school adaptation, there is significant difference between experimental group and control group(t=.05, p<.05).

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