• Title/Summary/Keyword: coefficient-based method

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A novel method for determining dose distribution on panoramic reconstruction computed tomography images from radiotherapy computed tomography

  • Hiroyuki Okamoto;Madoka Sakuramachi;Wakako Yatsuoka;Takao Ueno;Kouji Katsura;Naoya Murakami;Satoshi Nakamura;Kotaro Iijima;Takahito Chiba;Hiroki Nakayama;Yasunori Shuto;Yuki Takano;Yuta Kobayashi;Hironori Kishida;Yuka Urago;Masato Nishitani;Shuka Nishina;Koushin Arai;Hiroshi Igaki
    • Imaging Science in Dentistry
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    • v.54 no.2
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    • pp.129-137
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    • 2024
  • Purpose: Patients with head and neck cancer (HNC) who undergo dental procedures during radiotherapy (RT) face an increased risk of developing osteoradionecrosis (ORN). Accordingly, new tools must be developed to extract critical information regarding the dose delivered to the teeth and mandible. This article proposes a novel approach for visualizing 3-dimensional planned dose distributions on panoramic reconstruction computed tomography (pCT) images. Materials and Methods: Four patients with HNC who underwent volumetric modulated arc therapy were included. One patient experienced ORN and required the extraction of teeth after RT. In the study approach, the dental arch curve (DAC) was defined using an open-source platform. Subsequently, pCT images and dose distributions were generated based on the new coordinate system. All teeth and mandibles were delineated on both the original CT and pCT images. To evaluate the consistency of dose metrics, the Mann-Whitney U test and Student t-test were employed. Results: A total of 61 teeth and 4 mandibles were evaluated. The correlation coefficient between the 2 methods was 0.999, and no statistically significant difference was observed (P>0.05). This method facilitated a straightforward and intuitive understanding of the delivered dose. In 1 patient, ORN corresponded to the region of the root and the gum receiving a high dosage (approximately 70 Gy). Conclusion: The proposed method particularly benefits dentists involved in the management of patients with HNC. It enables the visualization of a 3-dimensional dose distribution in the teeth and mandible on pCT, enhancing the understanding of the dose delivered during RT.

Comparative analysis of Glomerular Filtration Rate measurement and estimated glomerular filtration rate using 99mTc-DTPA in kidney transplant donors. (신장이식 공여자에서 99mTc-DTPA를 이용한 Glomerular Filtration Rate 측정과 추정사구체여과율의 비교분석)

  • Cheon, Jun Hong;Yoo, Nam Ho;Lee, Sun Ho
    • The Korean Journal of Nuclear Medicine Technology
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    • v.25 no.2
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    • pp.35-40
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    • 2021
  • Purpose Glomerular filtration rate(GFR) is an important indicator for the diagnosis, treatment, and follow-up of kidney disease and is also used by healthy individuals for drug use and evaluating kidney function in donors. The gold standard method of the GFR test is to measure by continuously injecting the inulin which is extrinsic marker, but it takes a long time and the test method is complicated. so, the method of measuring the serum concentration of creatinine is used. Estimated glomerular filtration rate (eGFR) is used instead. However, creatinine is known to be affected by age, gender, muscle mass, etc. eGFR formulas that are currently used include the Cockroft-Gault formula, the modification of diet in renal disease (MDRD) formula, and the chronic kidney disease epidemilogy collaboration (CKD-EPI) formula for adults. For children, the Schwartz formula is used. Measurement of GFR using 51Cr-EDTA (diethylenetriamine tetraacetic acid), 99mTc-DTPA (diethylenetriamine pentaacetic acid) can replace inulin and is currently in use. Therefore, We compared the GFR measured using 99mTc-DTPA with the eGFR using CKD-EPI formula. Materials and Methods For 200 kidney transplant donors who visited Asan medical center.(96 males, 104 females, 47.3 years ± 12.7 years old) GFR was measured using plasma(Two-plasma-sample-method, TPSM) obtained by intravenous administration of 99mTc-DTPA(0.5mCi, 18.5 MBq). eGFR was derived using CKD-EPI formula based on serum creatinine concentration. Results GFR average measured using 99mTc-DTPA for 200 kidney transplant donors is 97.27±19.46(ml/min/1.73m2), and the eGFR average value using the CKD-EPI formula is 96.84±17.74(ml/min/1.73m2), The concentration of serum creatinine is 0.84±0.39(mg/dL). Regression formula of 99mTc-DTPA GFR for serum creatinine-based eGFR was Y = 0.5073X + 48.186, and the correlation coefficient was 0.698 (P<0.01). Difference (%) was 1.52±18.28. Conclusion The correlation coefficient between the 99mTc-DTPA and the eGFR derived on serum creatinine concentration was confirmed to be moderate. This is estimated that eGFR is affected by external factors such as age, gender, and muscle mass and use of formulas made for kidney disease patients. By using 99mTc-DTPA, we can provide reliable GFR results, which is used for diagnosis, treatment and observation of kidney disease, and kidney evaluation of kidney transplant patients.

A Hardwired Location-Aware Engine based on Weighted Maximum Likelihood Estimation for IoT Network (IoT Network에서 위치 인식을 위한 가중치 방식의 최대우도방법을 이용한 하드웨어 위치인식엔진 개발 연구)

  • Kim, Dong-Sun;Park, Hyun-moon;Hwang, Tae-ho;Won, Tae-ho
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.11
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    • pp.32-40
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    • 2016
  • IEEE 802.15.4 is the one of the protocols for radio communication in a personal area network. Because of low cost and low power communication for IoT communication, it requires the highest optimization level in the implementation. Recently, the studies of location aware algorithm based on IEEE802.15.4 standard has been achieved. Location estimation is performed basically in equal consideration of reference node information and blind node information. However, an error is not calculated in this algorithm despite the fact that the coordinates of the estimated location of the blind node include an error. In this paper, we enhanced a conventual maximum likelihood estimation using weighted coefficient and implement the hardwired location aware engine for small code size and low power consumption. On the field test using test-beds, the suggested hardware based location awareness method results better accuracy by 10 percents and reduces both calculation and memory access by 30 percents, which improves the systems power consumption.

Analyses on Environment-friendliness of Waterproof Materials Based on Fish Toxicity Test (어독성 실험에 따른 방수재 친환경 특성 분석)

  • Kim, Sung-Kyun;Woo, Ji-Keun;Lee, Im-Gyu;Yoo, Hy-Ein;Jeong, Jae-Wook
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.13 no.1
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    • pp.57-68
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    • 2010
  • The purpose of this study is to analyze the characteristics of environment-friendliness of waterproof materials based on comprehensive experiments on waterproofness in terms of coefficients of permeability, harmfulness of waterproof materials and fish toxicity of Oryzias latipes mortality to verify eco-toxicity of each method of construction and waterproof material, which are to be applied by taking eco-toxicity into account when building ecological flows in upper areas on natural and artificial grounds. As a result, the following conclusions have been reached in this study: 1. In regard of the harmfulness analyzed, each material showed a different result of analytical value in each lab tank. Compared to input water, pH, COD, SS, T-P, and T-N values increased a little, but DO value decreased. The value of turbidity analyzed independent of the water quality standard of aquatic ecosystem set forth by the Ministry of Environment increased a little compared to the value in input water. 2. In the experiment of fish toxicity, compacted quicklime, cement fluid waterproof material, cement mortar waterproof material and bentonite powder were found to have 100% of fish mortality, respectively, and membrane waterproof material showed 83.3% of mortality, indicating strong fish toxicity. Improved asphalt sheet (63.3%) and synthetic rubber sheet (53.3%) were analyzed to have medium fish toxicity, while bentonite sheet (6.7%), Hwang-toh (6.7%) and clay (3.3%) showed relatively lower mortality and fish toxicity. 3. Regarding the analysis on waterproofness in terms of the coefficient of permeability of each waterproof material, improved asphalt sheet, synthetic rubber sheet, membrane waterproof material, cement fluid and mortar waterproof material and bentonite sheet were found impervious in case no leakage takes place in construction. Bentonite powder was found practically impervious based on the analytical results from the experiment done in compliance with weight ratios. So were the clay and Hwang-toh from the experimental results. To sum up such results as found in the experiment mentioned so far, the values of harmfulness and waterproofness analyzed were different in each lab tank, but there was absolutely little correlation with the mortality gained from the experiment on fish toxicity. In the experiment of fish toxicity, environment-friendly waterproof materials were analyzed, and it was found that clay, Hwang-toh and bentonite sheet are highly environment-friendly. In contrast, synthetic rubber and improved asphalt sheets were found to have medium-level environment-friendliness. Also, membrane water-proof materials, compacted quicklime, cement fluid and mortar waterproof material and bentonite powder were analyzed to have low environment-friendliness.

Synthesis, Dispersion, and Tribological Characteristics of Alkyl Functionalized Graphene Oxide Nanosheets for Oil-based Lubricant Additives (액체 윤활제 첨가제용 알킬 기능화된 산화 그래핀의 합성/분산 및 트라이볼로지적 특성)

  • Choe, Jin-Yeong;Kim, Yong-Jae;Lee, Chang-Seop
    • Applied Chemistry for Engineering
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    • v.29 no.5
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    • pp.533-540
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    • 2018
  • Graphene has been reported to be an excellent lubricant additive that reduces friction and wear when coated on the surface of various materials or when dispersed in lubricants as an atomic thin material with the low surface energy. In this study, alkyl functionalized graphene oxide (FGO) nanosheets for oil-based lubricant additives were prepared by using three types of alkyl chloride chemicals (butyl chloride, octyl chloride, and tetradecyl chloride). The chemical and structural properties of the synthesized FGOs were analyzed by Fourier transform infrared (FT-IR), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscope (SEM), and transmission electron microscope (TEM). The synthesized FGOs were dispersed at 0.02 wt% in PAO-0W40 oil and its tribological characteristics were investigated using a high frequency friction/wear tester. The friction coefficient and the wear track width of poly alpha olefin (PAO) oil added with FGO-14 were tested by a ball-on-disk method, and the measured results were reduced by ~5.88 and ~3.8%, respectively compared with those of the conventional PAO oil. Thus, it was found that the wear resistance of PAO oil was improved. In this study, we demonstrated the successful functionalization of GO as well as the improvement of dispersion stability and tribological characteristics of FGOs based on various alkyl chain lengths.

Estimation of Actual Evapotranspiration over Paddy Rice Field (수도 포장의 실증발산량 추정에 관한 연구)

  • 이변우;김병찬
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.35 no.6
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    • pp.518-524
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    • 1990
  • Actual evapotranspiration was measured over rice paddy field by Bowen ratio heat balance method and based on this, investigated was the reliability of actual evapotranpiration estimation from Class-A Pan and small pan evaporation and reference evapotranspiration calculated by modified Penman-Monteith model. Crop coefficients based on Class-A Pan and small pan evaporation and reference evapotranspiration by modified Penman-Monteith model were averaged to be 1.57. 1.10 and 1.49 over the whole rice growing season, respectively. Their respective coefficients of variation were 28.7. 22.7 and 12.8 percent, respectively. Crop coefficient based on modified Penman-Monteith model varied in good agreement with the trend of leaf area development, being greatest around heading stage.

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Studies of Specific Foods to Absolute Intake and Between-Person-Variance in Various Nutrients Intake (농촌거주 청소년의 식이조사에서 나타난 영양소의 주된 공급식품과 변이식품의 양상)

  • 김영옥
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.6
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    • pp.892-900
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    • 1995
  • Dietary data of 538 middle school students have been analysed to identify the contribution of specific foods to absolute intake and between-person-variance in nutrient consumption. The 24-hour-dietary-recall method had been used to collect the data required. Contribution of specific foods, in terms of ranking order for both absolute intake and between-person-variance have been observed. Ranking order of food for absolute intake was given based on the percen of contribution whereas the ranking order of foods for between-person-variance was given based on the percent of contribution whereas the ranking order of foods for between-person-variance was given based on a coefficient fo variation. As a result, for most of the nutrients(except cholesterol), the ranking order of foods for the between-person-variance was quite different from that of absolute intake. The results indicate that to identify between-person-variance of nutrient intake in an epidemiology study, foods with a high ranking in between-person-variance should be included in developing the food frequency questionnaires rather than foods which showed a high ranking in absolute intake.

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Spatial Extension of Runoff Data in the Applications of a Lumped Concept Model (집중형 수문모형을 활용한 홍수유출자료 공간적 확장성 분석)

  • Kim, Nam Won;Jung, Yong;Lee, Jeong Eun
    • Journal of Korea Water Resources Association
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    • v.46 no.9
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    • pp.921-932
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    • 2013
  • Runoff data availability is a substantial factor for precise flood control such as flood frequency or flood forecasting. However, runoff depths and/or peak discharges for small watersheds are rarely measured which are necessary components for hydrological analysis. To compensate for this discrepancy, a lumped concept such as a Storage Function Method (SFM) was applied for the partitioned Choongju Dam Watershed in Korea. This area was divided into 22 small watersheds for measuring the capability of spatial extension of runoff data. The chosen total number of flood events for searching parameters of SFM was 21 from 1991 to 2009. The parameters for 22 small watersheds consist of physical property based (storage coefficient: k, storage exponent: p, lag time: $T_l$) and flood event based parameters (primary runoff ratio: $f_1$, saturated rainfall: $R_{sa}$). Saturated rainfall and base flow from event based parameters were explored with respect to inflow at Choongju Dam while other parameters for each small watershed were fixed. When inflow of Choongju Dam was optimized, Youngchoon and Panwoon stations obtained average of Nash-Sutcliffe Efficiency (NSE) were 0.67 and 0.52, respectively, which are in the satisfaction condition (NSE > 0.5) for model evaluation. This result is showing the possibility of spatial data extension using a lumped concept model.

Development of Automatic Nutrient-Solution Mixing System Using a Low-Cost and Precise Liquid Metering Device (액제 정밀계량 장치를 이용한 양액 자동조제 시스템 개발)

  • 이규철;류관희;이정훈;김기영;황호준
    • Journal of Biosystems Engineering
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    • v.22 no.4
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    • pp.469-478
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    • 1997
  • This study was conducted to develop an automatic nutrient-solution mixing system for small-scale sewers. The nutrient-solution mixing system consisted of a low-cost and precise metering device and data acquisition & control system with a personal computer. and, the metering device was composed of three parts those were supply pumps, metering cylinders and venturi tube. The system controlled electric conductivity(EC) and pH of nutrient-solution based on the time-based feedback control method with the information about temperature, EC, and pH of the nutrient-solution. The performance of the nutrient-solution mixing system was evaluated through the control of EC and pH while compared with those of commercial system. Also an experimental cultivation of tomato was conducted to verify and to improve the developed system. Results of this study were as follows. 1. The correlation coefficient of meteing device between the flow rate and operating time was 0.9999, and the linear reuession equation computed was y=21.759x, where y is the discharge($g$) and x is the operating time(s). 2. Calculated errors for the developed metering device and two commercial pump were $\pm$0.3% $\pm$2.45% and $\pm$1.38 % FS error respectively. 3. An automatic nutrient-solution mixing system based on a low-cost and precise metering device was developed. 4. The full scale errors of the developed system in controlling EC and pH at 23$\pm$1$^{\circ}C$ were $\pm$0.05mS/cm and $\pm$0.2, respectively 5. When using the commercial system, the controlled values of EC and pH of the 500 $\ell$ of water were 1.29 mS/cm and 6.1 pH for the setting points of 1.4 mS/cm and 6.0 pH respectively at 23$pm1^{\circ}C$. 6. The developed nutrient-solution control system showed $\pm$0.05 ms/cm of deviation from the setting EC value over the experimental cultivation period. 7. The deviation from the average values of Ca and Mg mass content in the several nutrient-solution were 0.5% and 1.8% respectively.

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Development of the PDA Based Mobile System for Body Fat Measurement and Diagnosis Using Bioelectrical Impedance Method (체임피던스 방법을 이용한 PDA 기반의 휴대용 체지방 측정 및 진단 시스템 개발)

  • 권세윤;이상민;김재환;우지환;김인영;이형기;방석원;김선일
    • Journal of Biomedical Engineering Research
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    • v.25 no.1
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    • pp.21-26
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    • 2004
  • Recently, many people want to know their state of health, such as a body fat rate, anywhere and anytime. The Personal Digital Assistance(PDA) is the portable wireless apparatus that has become widely popular. There are many application areas of the IDA to be in mobile care devices. In this study, we developed the PDA based body fat measurement system, composed of a cradle type measurement module and a WindowCE operated software module, a regression equation for predicting lean body mass (LBM). Sixty-three weight-stable subjects (53 men, 10 women) aged 20∼32yr participated in this study. A regression model, LBM = (0.0005*Height2 - 0.0160*Impedance + 0.3920*Weight - 0.0684*Age - 5.8141*Sex + 25.984, was found. The correlation coefficient( r) of body fat rate between developed system and HTM1000plus(BionetTM) was 0.928. HTM1000plus is a commercially available and approved by KFDA. These results indicated that developed system is reliable for estimation of body fat rate. Although developed system is the PDA based miniaturized, it shows good performance comparing with other commercial product.