• 한국가금학회지
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• 제39권1호
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• pp.17-25
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• 2012

Coccidiosis control programs such as vaccines or in-feed anticoccidials are commonly practiced in the poultry industry to improve growth performance and health of commercial broiler chickens. In this study, we assessed the effects of various coccidiosis control programs (e.g., in ovo vaccination, synthetic chemicals, and antibiotic ionophores) on immune status of broiler chickens vaccinated against infectious bronchitis virus and Newcastle disease virus (ND) and raised on an Eimeria-contaminated used litter. In general, the levels of ${\alpha}$-1-acid glycoprotein, an acute phase protein, were altered by the treatments when measured at 34 days of age. Splenocyte subpopulations and serum antibody titers against ND were altered by various coccidiosis control programs. In-ovo-vaccinated chickens exhibited highest mitogenic response when their spleen cells were stimulated with concanavalin A (Con A) at 7 days of age. It is clear from this study that the type of coccidiosis control program influenced various aspects of innate and adaptive immune parameters of broiler chickens. Further studies will be necessary to delineate the underlying relationship between the type of coccidiosis control program and host immune system and to understand the role of other external environmental factors such as gut microbiota on host-pathogen interaction in various disease control programs.

• 한국가금학회지
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• 제20권1호
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• pp.17-31
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• 1993

Several aspects about the epidemiological status of chicken coccidiosis, its control measures and recent research activities in Korea are discussed in this paper. Medication with different available anticoccidial drugs has been reasonably effective in treating and preventing serious outbreaks of coccidiosis in chicken, but the disease remains one of the most expensive and common diseases of popultry production in this country, and more recently its incidence is increasing, possibly due to the more intensive methods of husbandry and the immergence of resistant strains of coccidia. Therefore, this necessitates a continuous search for new methods such as medication program (shuttl and rotation program) and immunization using attenuated strains or parasite antigens.

• 한국가금학회지
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• 제19권3호
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• pp.151-160
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• 1992

현재 콕시듐 병의 방제는 약제 투여, 사육관리, 백신을 이용하거나 혹은 이들 방법을 적당히 혼합하여 실시하고 있다. 약제 투여 방법은 약의 내성이라는 문제점을 내재하고 있지만 아직도 콕시듐 방제에 최우선 방법으로 쓰고 있으며 이러한 약제 내성을 조금이나마 지연시키기 위하여 shuttle, 혹은 rotation program을 쓰고 있다. 따라서 약제 내성 검사는 각 농장에 어떠한 약제가 효과가 있는지를 알아보는데 가장 중요한 방법이 되어 왔던 것이다. 콕시듐 방제에 있어서 사육관리에 의한 방법은 아직은 완전한 효과적인 방법으로 정착되지 않았는데 그 이우는 소독제만으로는 콕시듐의 원충을 죽일 수 없기 때문이다. 백신에 의한 방법은 현재까지 살아있는 콕시듐 원충을 제한적으로 쓰고 있는 단계이다. 새로운 형태의 백신개발이 요즈음 연구가 되고 있는데 이 백신은 순화시킨 콕시듐 원충을 사용하거나 유전공학적 방법 혹은 원충의 일부분에 대한 항원을 추출하여 백신으로 이용하는 것이다.