• Journal of Microbiology and Biotechnology
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• 제8권6호
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• pp.650-655
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• 1998

The chromosomal DNA fragment from Phaffia rhodozyma CBS 6938 which is able to autonomously replicate in the yeast Saccharomyces cerevisiae was cloned on an integrative URA3 plasmid. Its minimal fragment exhibiting autonomously replicating activiy in the S. cerevisiae gave a higher frequency transformation efficiency than that found for centromere-based plasmid, and enabled extrachromosoma1ly stable transmission of the plasmids in one copy per yeast cell under non-selective culture condition. The 836-bp DNA element lacked an ORF and did not contain any acceptable match to an ARS core consensus. Sequence analysis, however, displayed a cluster of three hairpin-Ioop-sequences with individual $\triangle {G_{25}}^{\circ}C$ free energy value of -10.0, -17.5, and -17.0 kcal. $mor^{-l}$as well as a 9-bp sequence with two base pair mismatches to the S. cerevisiae/E. coli gyrase-binding site. This 836-bp sequence also included one 7-bp sequence analogous to the core consensus of centromeric DNA element III (CDEIII) of S. cerevisiae, but CDEIII-like 7 bp sequence alone did not give a replicative function in this yeast.

• 한국경영과학회:학술대회논문집
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• 한국경영과학회 2005년도 추계학술대회 및 정기총회
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• pp.133-164
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• 2005

Mobile games have emerged as the most innovative entertainment technology, adding new revenue streams, taking advantage of the potential of wireless applications and service offerings. Mobile games, like any other types of computer game, offer a unique value for users in providing an exciting digital experience in virtual worlds. Players can become empowered through the development of new characters and strategies within games to achieve rewarding successes against the computers and other players. The overall trend for mobile games is towards bigger, more colorful, more involving and exciting contents, which will build upon the developing capabilities of mobile phones and networks in order to bring new styles, concepts and experiences of game play to the users. In this paper, we attempt to investigate the demographic factors which play critical roles in determining the level of playing times; classify mobile gamers based on their motives for playing games; and empirically test differences in their demographic factors and mobile game usage. Statistical results show that significant differences in playing times exist, depending upon their age, gender, mobile device, mobile phone usage, mobile game experiences, and preferred games genres. Applying Factor analysis, we have identified Escape, Social interaction, Challenge and Competition, Fantasy, Diversion and Relaxation, Ease of Accessibility as key motivators for playing mobile games. Additional cluster analysis shows that the categorization of gamers, according to their usage habits and the key motivators for playing, can be made as follows: M-gamers, Multi-gamers and Communication-focused gamers. Further correlation of these grouping with socio-economic data shows the significant differences in gaming habits and patterns of mobile phone use.

• Asian-Australasian Journal of Animal Sciences
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• 제28권8호
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• pp.1194-1201
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• 2015

This study investigated the effect of oxidized soybean oil in the diet of young chickens on growth performance and intestinal oxidative stress, and indices of intestinal immune function. Corn-soybean-based diets containing 2% mixtures of fresh and oxidized soybean oil provided 6 levels (0.15, 1.01, 3.14, 4.95, 7.05, and $8.97meqO_2/kg$) of peroxide value (POV) in the diets. Each dietary treatment, fed for 22 d, had 6 replicates, each containing 30 birds (n = 1,080). Increasing POV levels reduced average daily feed intake (ADFI) of the broilers during d 1 to 10, body weight and average daily gain at d 22 but did not affect overall ADFI. Concentrations of malondialdehyde (MDA) increased in plasma and jejunum as POV increased but total antioxidative capacity (T-AOC) declined in plasma and jejunum. Catalase (CAT) activity declined in plasma and jejunum as did plasma glutathione S-transferase (GST). Effects were apparent at POV exceeding $3.14meqO_2/kg$ for early ADFI and MDA in jejunum, and POV exceeding $1.01meqO_2/kg$ for CAT in plasma and jejunum, GST in plasma and T-AOC in jejunum. Relative jejunal abundance of nuclear factor kappa B ($NF-{\kappa}B$) P50 and $NF-{\kappa}B$ P65 increased as dietary POV increased. Increasing POV levels reduced the jejunal concentrations of secretory immunoglobulin A and cluster of differentiation (CD) 4 and CD8 molecules with differences from controls apparent at dietary POV of 3.14 to $4.95meqO_2/kg$. These findings indicated that growth performance, feed intake, and the local immune system of the small intestine were compromised by oxidative stress when young broilers were fed moderately oxidized soybean oil.

• Asian-Australasian Journal of Animal Sciences
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• 제31권2호
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• pp.157-162
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• 2018

Objective: The aim of this study is to identify single nucleotide polymorphisms (SNPs) and genes related to pig IMF and estimate the heritability of intramuscular fat content (IMF). Methods: Genome-wide association study (GWAS) on 704 inbred Berkshires was performed for IMF. To consider the inbreeding among samples, associations of the SNPs with IMF were tested as random effects in a mixed linear model using the genetic relationship matrix by GEMMA. Significant genes were compared with reported pig IMF quantitative trait loci (QTL) regions and functional classification of the identified genes were also performed. Heritability of IMF was estimated by GCTA tool. Results: Total 365 SNPs were found to be significant from a cutoff of p-value <0.01 and the 365 significant SNPs were annotated across 120 genes. Twenty five genes were on pig IMF QTL regions. Bone morphogenetic protein-binding endothelial cell precursor-derived regulator, forkhead box protein O1, ectodysplasin A receptor, ring finger protein 149, cluster of differentiation, tyrosine-protein phosphatase non-receptor type 1, SRY (sex determining region Y)-box 9 (SOX9), MYC proto-oncogene, and macrophage migration inhibitory factor were related to mitogen-activated protein kinase pathway, which regulates the differentiation to adipocytes. These genes and the genes mapped on QTLs could be the candidate genes affecting IMF. Heritability of IMF was estimated as 0.52, which was relatively high, suggesting that a considerable portion of the total variance of IMF is explained by the SNP information. Conclusion: Our results can contribute to breeding pigs with better IMF and therefore, producing pork with better sensory qualities.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10335-10337
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• 2015

Background: Gastric cancer is considered as the second most prevalent cancer in Iran. The present research sought to identify high risk clusters of gastric cancer with mapping using space-time scan statistics. Materials and Methods: The present research is of descriptive type. The required data were gathered from the registered cancer reports of Cancer Control Office in the Center for Non Communicable Disease of the Ministry of Health (MOH). The data were extracted at province level in the time span of 2004-9. Sat-Scan software was used to analyse the data and to identify high risk clusters. ArcGIS10 was utilized to map the distribution of gastric cancer and to demonstrate high risk clusters. Results: The most likely clusters were found in Ardabil, Gilan, Zanjan, East-Azerbaijan, Qazvin, West-Azerbaijan, Kurdistan, Hamadan, Tehran and Mazandaran between 2007 and 2009. It was statistically significant at the p-value below 0.05. Conclusions: High risk regions included Northern, West-North and central provinces, particularly Ardabil, Kurdistan, Mazandaran and Gilan. More screening tests are suggested to be conducted in high risk regions along with more frequent epidemiological studies to enact gastric cancer prevention programs.

• 한국환경생태학회지
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• 제23권2호
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• pp.143-150
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• 2009

변산반도 국립공원 신선봉지역의 능선부 식생구조를 파악하고자 능선부에 방형구($400m^2$) 14개를 설정하여 식생을 조사하였다. 식물군집을 분류한 결과 14개 조사구는 굴참나무졸참나무군집, 개서어나무군집의 2개 군집으로 분류되었다. 신선봉지역의 능선부는 대부분 굴참나무와 졸참나무가 우점하고 있었으며 해발고가 높은 일부지역에 개서어나무가 우점하는 임분이 나타나고 있었다. 수종간의 상관관계에서는 굴참나무와 말오줌대는 부의 상관이 인정되었고, 때죽나무와 졸참나무, 말오줌대와 철쭉, 피나무, 쪽동백나무와 산딸나무, 철쭉과 서어나무, 산딸나무와 피나무는 정의 상관이 인정되었다. 조사지의 군집별 종다양성 지수는 $1.237{\sim}l.497$의 범위로 다른 국립공원들의 식생구조에 비하여 다소 높게 나타났다.

• 한국경제지리학회지
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• 제21권2호
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• pp.173-191
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• 2018

이 연구는 사회적 경제에 관한 학술적 관심과 정책적 적용이 증가하는 추세에 주목하여 사회적 경제를 공간적 관점에서 바라보는 지리학의 연구 주제를 정리하려는 목적으로 이루어졌다. 사회적 경제가 갖는 사회적 가치의 추구라는 지향성은 독특한 공간 특성을 나타낼 것이라 보았고, 이를 위해 사회혁신, 사회적 경제조직, 사회적 기업 등 관련 개념을 통해 공간적 의미를 갖는 요소를 도출하였다. 사회적 경제의 공간적 맥락을 이해하는 방법으로서 사회적 기업가정신이 발현되는 공간의 성격, 사회적 경제조직의 의사결정이 갖는 장소기반의 맥락, 사회적 문제 해결이라는 수요와 사회적 경제조직의 활동을 지원하는 공급의 특성이 상호작용하며 만들어가는 공간의 특성에 주목할 것이 제안된다. 사회혁신클러스터에 대해서는 기존의 산업클러스터와 차별화되는 특성을 밝히는 것이 중요함을 지적한다. 지역사회와 갖는 밀착의 본질, 당위성, 요소에 대해서는 착근성 개념을 적용할 것을 제안한다.

• 한국관광식음료학회지:관광식음료경영연구
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• 제17권1호
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• pp.41-67
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• 2006

The study is aimed to analyze the influence of FTA(Free Trade Agreement) between Korea and Japan on tourism and to suggest ways to increase tourists exchange between them by considering countermeasures of Korea's tourism based on the analysis and deriving political significance. The results of the study showed that the expected effects of FTA between Korea and Japan on tourism would overall be positive. There would be increases in employment and a higher rate of foreign-exchange earning, which plays a critical role in the cash flow. Therefore the government is required to prepare for several political measures as follows. First, ways to promote investment in tourism have to be established in a systematic way for FTA. Second, restructuring of tourism has to be considered seriously for tourism to be a high value-added industry after FTA. Third, the tourism information industry needs to be included in the tourism promotion act to promote e-tourism using information technology. In addition to this, an expansive cluster strategy needs to be developed, which relates tourism to other industries like culture and movies and to find ways to re-locate and re-educate manpower currently engaged in the tourism industry. Though the study investigated the influence of FTA on tourism through a practical analysis, it was restricted only to Korea. So the influence of FTA between Korea and Japan on the tourism of Japan should be included in further study. Furthermore, in subsequent studies the CGE(Computable General Equilibrium) model will be applied for objective analysis of the effects. Or measuring the ripple effect with multinational inter-industry relation table will be made for the study to make practical contributions to the development of government policy.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 추계학술대회 논문집 Vol.21
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• pp.341-342
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• 2008

The dynamics of nano particles in LC medium under an external electric field is of theoretical and technological interest. In this work, the dynamical characteristics of fullerene $(C_{60})$ particles in liquid crystal (LC) medium under dc electric field have been investigated. This effect was studied for homogeneously aligned nematic LC cells driven by in-plane field. The $C_{60}$ was found to be aggregated in a form of cluster inside the LC medium. Hence polystytene was used to protect the aggregation of $C_{60}$ in LC medium. When the electric field was applied, the fullerenes start to move in direction of applied electric field. The density of $C_{60}$'s particles at the electrodes increase with increase in the value of applied electric field. The dynamical motions of fullerene $(C_{60})$ particles in liquid crystal (LC) suggest that fullerene can be designed for electrophoretic displays (i.e., electronic ink).

• 한국농촌생활과학회지
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• 제5권2호
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• pp.93-106
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• 1994

The purpose of this study was to develop the pattern of bodysuit and to identify the wear fitness of it The methods of statistical analysis applied to the study were ANOVA and cluster analysis. The materials used in making bodysuit were Nylon/Polyurethane, lace, power net, binding tape, and hook eye. The try-on test was administered in two aspects ; (1) the comparison of anthropometric data before and after trying on the experimentally constructed bodysuit with those of marketing bodysuit, (2) the sensory evaluation to estimate the wear fitness in terms of appearance and motion function. The conclusions obtained are as follows ; 1. In the survey of wearing state, 52.2% of respondents had experience of wearing bodysuit. 60.6% of them responded to the item, “well-balanced body” in the question about the purpose of wearing it. 55.7% considered the item, “feel choky in the chest” as uncomfortable point in putting on bodysuit. 48.3% felt the portion of crotch drawn above in taking exercise or behaving routinely in everyday life. 2. As for the characteristics of the bodysuit design, the scooped neckline and horizontal outline without wire in lower bust was used, the adjust point being located right above the perineum point, and the length of bodysuit is as far as trochanteric point. 3. In comparing anthropometric data of the subjects, there was significant difference in the height of lower bust the distance around abdomen, and the length of bust point(right, left) between the experimentally constructed bodysuit and the marketing bodysuit. 4. Concerning the results of the try-on test in appearance, the estimates of expert panel, which were in agreement with those of subjects in mean value and composite reliability coefficient, showed that the pattern fitness of experimentally designed bodysuit was higher than that of marketing bodysuit. 5. To take try-on test in motion function, motion was classified the five steps. The results of the test showed that experimentally designed bodysuit was fitter in each steps of motion than marketing bodysuit.