• 원예과학기술지
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• 제29권4호
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• pp.382-387
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• 2011

The chemical composition of essential oils obtained from aerial parts in spearmint, apple mint and chocolate mint, was investigated by gas chromatography/mass spectrometry analyses. (-)-Carvone (33.0%) was quantitatively major compound in spearmint, followed by R-(+)-limonene (11.7%) and ${\beta}$-phellandrene (9.7%); (-)-carvone (37.4%) and germacrene D (11.9%) in apple mint; and (-)-menthol (34.3%), p-menthone (18.4%) and menthofuran (9.8%) in chocolate mint. Hierarchical cluster analysis and principle components analysis showed the clear difference in chemical composition of the three mint oils.

• Communications for Statistical Applications and Methods
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• 제23권5호
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• pp.433-444
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• 2016

When we observe binary responses in a cluster (such as rat lab-subjects), they are usually correlated to each other. In clustered binomial counts, the independence assumption is violated and we encounter an extra-variation. In the presence of extra-variation, the ordinary statistical analyses of binomial data are inappropriate to apply. In testing the homogeneity of proportions between several treatment groups, the classical Pearson chi-squared test has a severe flaw in the control of Type I error rates. We focus on modifying the chi-squared statistic by incorporating variance inflation factors. We suggest a method to adjust data in terms of dispersion estimate based on a quasi-likelihood model. We explain the testing procedure via an illustrative example as well as compare the performance of a modified chi-squared test with competitive statistics through a Monte Carlo study.

• 아동학회지
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• 제29권3호
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• pp.157-174
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• 2008

This study used the person-oriented approach to explore differences in narrative representations of 97 4-, 5- and 6-year old children (30 foster care, 40 biological family, 17 adopted). Using the MacArthur Story Stem Battery (Bretherton et al., 1990), observations were made to obtain children's narrative representations of content themes and performances. Descriptive statistics, ANOV A and hierarchical cluster analyses were performed. The results of this study were that : (1) Biological family children showed more empathy/helping representations. Foster care children and adopted children showed more anxious representations, and foster care children showed more dysregulated aggression. (2) Four clusters of foster care and adopted children and five clusters of family biological children were found.

• 복식
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• 제49권
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• pp.65-72
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• 1999

The purpose of this study was to investigate the relationships between body-calthexis and clothing image preferences in male college students. The sample included 28 male college students and an instrument was developed based on the previous studies. The statistical analyses used for this study were factor analysis cluster analysis and t-test. The result of factor analysis showed that body-cathexis consisted of four areas of body parts: face/head upper body middle body and lower/total body. Clothing image preferences consisted of 'strong vs weak' 'soft vs hard' 'young vs mature' 'mannis vs feminine' and 'distinguished vs undistinguished' images. Cluster analysis revealed that male college students are segmented into two groups. and the two groups differed in regard to clothing image preferences such as 'strong vs weak' 'young vs mature' and 'mannish vs feminine' images. In addition the two consumer segments were different concerning body-cathexis for middle body and all body areas combined. The consumers who preferred feminine weak and mature clothing images were more satisfied with their middle area of the bodies and all body areas combined.

• 가정과삶의질연구
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• 제6권1호
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• pp.223-249
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• 1988

The aim of this study is to classify the life styles of urban housewives, to see their correlation with demographic and socioeconomic variables, and finally to provide some useful for their ideal home management. This study has been based on a questionnaire on the demographic characteristics of housewives, and their life styles. The selected samples were 650 and 514 of them were analyzed. The data wee analyzed by factor analysis, cluster analysis, ANOVA, Duncan test and X2-test. As a result of factor and cluster analyses of 64 items th life styles of urban housewives were classified into 5 types; 'conservative stagnant type', 'sound and thrifty type', 'passive stagnant type', realistic and stable type', modern and evolutional type', The life styles of the respondents showed significant differences by the variables of age , family life cycles, the number of family members, the number of children, family type, education, occupation, income, the type of housing, and religion.

• Journal of Microbiology and Biotechnology
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• 제20권11호
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• pp.1484-1490
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• 2010

In the Streptomyces hygroscopicus JCM4427 geldanamycin biosynthetic gene cluster, five putative regulatory genes were identified by protein homology searching. Among those genes, gel14, gel17, and gel19 are located downstream of polyketide synthase genes. Gel14 and Gel17 are members of the LAL family of transcriptional regulators, including an ATP/GTP-binding domain at the N-terminus and a DNA-binding helix-turn-helix domain at the C-terminus. Gel19 is a member of the TetR family of transcriptional regulators, which generally act to repress transcription. To verify the biological significance of the putative regulators in geldanamycin production, they were individually characterized by gene disruption, genetic complementation, and transcriptional analyses. All three genes were confirmed as positive regulators of geldanamycin production. Specifically, Gel17 and Gel19 are required for gel14 as well as gelA gene expression.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2004년도 한국우주과학회보 제13권2호
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• pp.321-324
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• 2004

We used BV CCD images to study the dynamical substructures of three globular clusters - M5, NGC6934, NGC7006 - analyzing the radial variations of ellipticity and position angle from the point spread function stellar photometry and the ellipse surface photometry. Several populations were classified by the brightness on color-magnitude diagrams of each globular cluster. Ellipse analyses to the images, removed stars of each population from the original images of the clusters, show radial variations in ellipticity and position angle, with the amount of $0.01\~0.25$ in ellipticity and $+90\~-90$ degrees in position angle up to roughly three times of half light radius $(r_h)$. It is also apparent that there are no significant discrepancies in the dynamical substructures beyond $r_h$ among the different populations. However, dynamical substructures on the central region (i.e., inner than $\~r_h$) reflect the contributions of populations of bright red giant stars and horizontal branch stars.

• 한국해양공학회지
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• 제34권6호
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• pp.461-468
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• 2020

This study examined how national research and development (R&D) in the domain of logistics has changed recently in the Republic of Korea. We conducted basic statistical analysis and social network analysis on 5,327 logistics-related R&D projects undertaken during 2005-2019. Data for performing these analyses were collected from the R&D database of the National Science and Technology Information Service (NTIS). By constructing a co-occurrence matrix with keywords, we conducted degree and betweenness centrality analysis and visualized the network matrix to display a cluster map. This study presents our observations related to the following findings: (1) the chronical trends of logistics R&D, (2) focused fields of logistics R&D, (3) the relations among keywords, and (4) the characteristics of logistics R&D. Finally, we suggest policy implications to boost and diversify logistics R&D.

• Molecules and Cells
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• 제46권12호
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• pp.736-742
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• 2023

NifB, a radical S-adenosylmethionine (SAM) enzyme, is pivotal in the biosynthesis of the iron-molybdenum cofactor (FeMo-co), commonly referred to as the M-cluster. This cofactor, located within the active site of nitrogenase, is essential for the conversion of dinitrogen (N₂) to NH₃. Recognized as the most intricate metallocluster in nature, FeMo-co biosynthesis involves multiple proteins and a sequence of steps. Of particular significance, NifB directs the fusion of two [Fe₄S₄] clusters to assemble the 8Fe core, while also incorporating an interstitial carbide. Although NifB has been extensively studied, its molecular mechanisms remain elusive. In this review, we explore recent structural analyses of NifB and provide a comprehensive overview of the established catalytic mechanisms. We propose prospective directions for future research, emphasizing the relevance to biochemistry, agriculture, and environmental science. The goal of this review is to lay a solid foundation for future endeavors aimed at elucidating the atomic details of FeMo-co biosynthesis.

• 한국식품영양과학회지
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• 제39권1호
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• pp.54-63
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• 2010

Flavonoid 계열의 한 종류인 baicalin은 항염증, 항암, 항바이러스, 항세균 등의 효능을 가진다. 본 연구진은 선행연구를 통한 이전의 보고에서 baiclain이 adipogenesis pathway(지방세포 형성 경로)의 anti-adipogenic(지방세포 형성억제)과 pro-adipogenic(지방세포 형성 유도) factor들을 조절함으로써 비만 및 adipogenesis를 억제함을 밝혔다. 본 연구에서는, microarray 기술을 이용하여 3T3-L1 세포에서 baiclain이 유도하는 지방세포 형성 억제 효과에 대한 분자적 기작을 보다 상세하게 연구하고자 하였다. 지방세포의 분화 시간(0일, 2일, 4일 및 7일)과 분화 시 baicalin의 처리 유무에 따라 유전자 발현 양상을 분석하기 위해 해당 시료들을 microarray에 적용하였다. Microarray 결과로부터 2배이상의 변화가 있는 3972개의 유전자를 확보하였다. 그 유전자들의 발현 양상을 좀 더 자세히 살펴보기 위해 hierarchical clustering 분석을 진행하였고 그 결과로 20개의 cluster를 분류할 수 있었다. 그들 중 4개의 cluster는 분화의 전반적인 기간에서 baicalin의 첨가에 의해 뚜렷하게 상승(cluster 8과 cluster 10)하거나 반대로 뚜렷하게 감소(cluster 12와 cluster 14)하는 양상을 보였다. Cluster 8과 cluster 10에는 CHOP(CCAAT/enhancer-binding protein homologous protein), INSIG1(insulin induced gene 1), WISP2(WNT1 inducible signaling pathway protein 2), ADM(adrenomedullin), CCND2(cyclin D2), GRN(granulin) 및 TGFB3(transforming growth factor, beta 3)과 같은 세포 증식과 지방세포 형성 억제를 상승시키는 유전자들이 다수 포함되었다. 반대로 cluster 12와 cluster 14에는 세포 증식 억제, 세포 주기 억제 및 세포 성장 억제와 연관되거나 지방세포를 유도하는 유전자인 LTA(lympotoxin A), ACADSB(acyl-Coenzyme A dehydrogenase, short/branched chain), HMGCS2(3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2), IGFBP7(insulin-like growth factor binding protein 7), MERTK(c-merproto-oncogene tyrosine kinase), RASSF2(ras association(RalGDS/AF-6) domain family 2), RHOU(ras homolog gene family, member U) 및 SESN1(sestrin1) 등이 포함되었다. 결론적으로 baicalin은 세포 증식 및 지방세포 형성과 연관된 유전자들을 조절함으로써 지방세포의 분화를 억제하는 것으로 사료된다. 이러한 결과는 baicalin이 유도하는 지방세포 형성 억제 및 비만 억제 효과의 분자적 기작에 대한 중요한 정보를 제시한다.