• Title/Summary/Keyword: clinical disease

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Kawasaki disease in infants

  • Yeom, Jung Sook;Woo, Hyang Ok;Park, Ji Sook;Park, Eun Sil;Seo, Ji-Hyun;Youn, Hee-Shang
    • Clinical and Experimental Pediatrics
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    • v.56 no.9
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    • pp.377-382
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    • 2013
  • Kawasaki disease (KD) is an acute febrile illness that is the predominant cause of pediatric acquired heart disease in infants and young children. Because the diagnosis of KD depends on clinical manifestations, incomplete cases are difficult to diagnose, especially in infants younger than 1 year. Incomplete clinical manifestations in infants are related with the development of KD-associated coronary artery abnormalities. Because the diagnosis of infantile KD is difficult and complications are numerous, early suspicion and evaluation are necessary.

Clinical Features and Diagnosis of Hirschsprung's Disease (Hirschsprung's Disease의 임상 양상 및 진단)

  • Park, Woo-Hyun
    • Advances in pediatric surgery
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    • v.8 no.1
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    • pp.48-53
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    • 2002
  • Diagnosing Hirschprungs disease (HD) is a clinical challenge to pediatric surgeons. The cardinal symptoms are failure of passage of meconium within first 24 hours of life, abdominal distension, and vomiting. The severity of these symptoms and the degree of consitpation vary considerably between patients. HD is suspected on the basis of history and clinical findings and the diagnosis is established by radiological examination, anorectal manometry, and histochemical analysis of biopsy specimens. In this review, the advantages and pitfalls of each diagnostic modality are discussed. And a diagnostic approach utilizing these diagnostic modalities in children with suspicious HD is presented.

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Clinical research on Heart Disease Diagnosis in korea traditional medicine using Magnetocardiography(MCG) (Magnetocardiography(MCG)를 이용한 심병증의 진단에 관한 임상연구)

  • Song, Nak-Kun;Ryu, Yeon-Hee;Moon, Jin-Suk;Ahn, Kyoo-Seok;Choi, Sun-Mi
    • Korean Journal of Oriental Medicine
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    • v.10 no.2
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    • pp.109-119
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    • 2004
  • The aim of this study is to confirm clinical usefulness of MCG data by analyzing korea medical results of heart disease patients. We used the Heart Disease Questionnaire which asks for Qi deficiency-pattern, Blood deficiency-pattern, Yin deficiency-pattern, Yang deficiency-pattern, Qi stasis-pattern, Blood stasis-pattern, Heart heat-pattern, Phlegm-pattern. Magnetocardiography(MCG) is the measurement of magnetic fields emitted by the human heart from small currents by electrically active cells of the heart muscle. Comparing the MCG results and korea medical diagnosis, we showed clinical usefulness of MCG results and korea medical diagnosis.

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Clinical and Pathological Survey on the Occurrence of Johne's Disease of Cattle in South Korea (국내발생의 우 파라결핵병(Johne's Disease) 예에 대한 임상병리학적 추적조사 보고)

  • Lee Bang-Whan;Lim Bong-Ho;Ha Chang-Su;Seong Hong-Ryong
    • Journal of the korean veterinary medical association
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    • v.19 no.2
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    • pp.8-20
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    • 1983
  • Clinical and pathological survey on the first occurrence of Johne's disease in south Korea were practised from November 1979 to September 1982 in Kangweondo. The results obtained in the survey were as follows. 1. The clinical cases of the disease were fir

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Molecular mechanisms and therapeutic interventions in sarcopenia

  • Park, Sung Sup;Kwon, Eun-Soo;Kwon, Ki-Sun
    • Osteoporosis and Sarcopenia
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    • v.3 no.3
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    • pp.117-122
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    • 2017
  • Sarcopenia is the degenerative loss of muscle mass and function with aging. Recently sarcopenia was recognized as a clinical disease by the International Classification of Disease, 10th revision, Clinical Modification. An imbalance between protein synthesis and degradation causes a gradual loss of muscle mass, resulting in a decline of muscle function as a progress of sarcopenia. Many mechanisms involved in the onset of sarcopenia include age-related factors as well as activity-, disease-, and nutrition-related factors. The stage of sarcopenia reflecting the severity of conditions assists clinical management of sarcopenia. It is important that systemic descriptions of the disease conditions include age, sex, and other environmental risk factors as well as levels of physical function. To develop a new therapeutic intervention needed is the detailed understanding of molecular and cellular mechanisms by which apoptosis, autophagy, atrophy, and hypertrophy occur in the muscle stem cells, myotubes, and/or neuromuscular junction. The new strategy to managing sarcopenia will be signal-modulating small molecules, natural compounds, repurposing of old drugs, and muscle-specific microRNAs.

A Case of Parkinson's Disease Patient with Nausea and Vomiting Induced by Taking Levodopa (레보도파 복용으로 유발된 오심 및 구토를 호소하는 파킨슨병 환자 한방 치험 1례)

  • Kim, Se-won;Yang, Jung-yun;Lee, Yu-jin;Cho, Ki-ho;Jung, Woo-sang;Kwon, Seung-won;Choi, Ki-mun;Mun, Sang-kwan
    • The Journal of Internal Korean Medicine
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    • v.40 no.2
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    • pp.246-253
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    • 2019
  • Objective: In this care report, we address a case of a Parkinson's disease patient with nausea and vomiting. Methods: A patient was treated with Korean medicine therapies including herbal medication (Hyungbangjihwang-tang, Boikyangwie-tang), acupuncture, and electroacupuncture during 35 days of hospitalization. We evaluated the improvements of symptoms by checking the number of vomiting episodes and the presence of nausea. Results: During 35 days of Korean medicine treatment, there was improvement in patient's symptoms. The frequency of vomiting had decreased, and the nausea had decreased and not appeared for the last 7 days. Conclusions: This study suggested that Korean medicine therapies might be effective in relieving gastrointestinal symptoms of Parkinson's disease.

A Case Report of Korean Medicine for Raynaud's Disease with Redness of Hands (수부 발적을 호소하는 레이노병 환자의 한의 치험 1례)

  • Choi, Jeong-woo;Kim, Seo-young;Jun, Gyu-ri;Kim, Ha-ri;Park, Seong-uk;Park, Jung-mi;Ko, Chang-nam;Cho, Seung-yeon
    • The Journal of Internal Korean Medicine
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    • v.41 no.6
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    • pp.1307-1316
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    • 2020
  • This is a case report of Raynaud's disease improved by Korean medicine treatment. A patient suffering with redness of the hands for more than five years took Yanggyeoksanhwa-tang or Geopungcheonggi-san for 3 months. The change in symptoms was assessed with photographs and evaluating the subjective symptoms of patient. After the 25th treatment, the redness of the hands and the subjective symptoms showed improvement. These findings suggested that Korean medicine treatment could be an effective option for redness of the hands due to Raynaud's disease.

De Quervain's Disease after Delivery Treated with SBV Herbal-acupuncture : Clinical Study on 3 Cases (Sweet Bee Venom 약침을 이용한 산후 De Quervain's disease 치험 3례)

  • Bak, Ji-Young;Lee, Eun-Hee
    • The Journal of Korean Obstetrics and Gynecology
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    • v.23 no.4
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    • pp.196-209
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    • 2010
  • Purpose: To investigate effect of Sweet Bee Venom on postpartum's De Quervain's Disease. Methods: We investigated 3 patients diagnosed as De Quervain's Disease. Sweet Bee Venom Herbal-acupuncture was used for treatment of De Quervain's Disease, once every two days, 5 times. Pain, satisfaction at treatment and function of wrist were measured with VNS, Baumgaertner's nine point scale and dynamometer. Results: Pain reduction, functional improvement, increased grip power were found out in cases treated with Sweet Bee Venom Herbal-acupuncture. In every cases, they represent high subjective satisfaction with treatment. Conclusion: Clinical results show that Sweet Bee Venom Herbal-acupuncture has a good analgesic effect in De Quervain's Disease.

Diagnosis of Pulmonary Tuberculosis and Nontuberculous Mycobacterial Lung Disease in Korea

  • Kwon, Yong Soo;Koh, Won-Jung
    • Tuberculosis and Respiratory Diseases
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    • v.77 no.1
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    • pp.1-5
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    • 2014
  • The recovery of nontuberculous mycobacteria (NTM) from respiratory specimens and the number of patients with NTM lung disease have been rapidly increasing in Korea. An early differential diagnosis of NTM lung disease from pulmonary tuberculosis (TB) is important, as the therapeutic regimen differs from that of pulmonary TB, and it is not necessary to track the contacts of patients with NTM lung disease. However, differentiating NTM lung disease from pulmonary TB remains difficult, because the clinical presentations of the two diseases are similar and a definite diagnosis of NTM lung disease based on sputum culture takes time. This review focuses on the changing epidemiology, clinical and radiographic manifestation, and laboratory diagnosis of pulmonary TB and NTM lung disease in Korea.

Treatment and management of patients with inherited metabolic diseases (유전성 대사질환의 치료 및 관리)

  • Lee, Jin-Sung
    • Clinical and Experimental Pediatrics
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    • v.49 no.11
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    • pp.1152-1157
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    • 2006
  • Inherited metabolic disease is rare disorders that show symptoms mainly in pediatric age and early treatment is important for preventing complications of the disease. Recent development in molecular and biochemical techniques help clinicians with proper diagnosis of patients, however, many of the disease still remain lack of effective therapeutic strategies. Better understanding on biochemical and molecular basis of pathogenesis of the disease combined with advanced medical care would provide new sight on the disease that can also improve the quality of life and long-term prognosis of patients. Traditionally, there are several modalities in the treatment of metabolic diseases depend on the biochemical basis of the disease such as diet restriction, removing or blocking the production of toxic metabolites, and stimulating residual enzyme activity. The inherited metabolic disease is not familiar for many clinicians because the diagnosis is troublesome, treatment is complicated and prognosis may not as good as expected in other diseases. Recently, new therapeutic regimens have been introduced that can significantly improve the medical care of patients with metabolic disease. Enzyme replacement therapy has showed promising efficacy for lysosomal storage disease, bone marrow transplantation is effective in some disease and gene therapy has been trying for different diseases. The new trials for treatment of the disease will give us promising insight on the disease and most clinicians should have more interest in medical progress of the metabolic disease.