• 한국임상약학회지
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• 제25권2호
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• pp.80-93
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• 2015

Objective: Pegfilgrastim is recently introduced that is long acting G-CSF for prophylaxis of febrile neutropenia. Treatment of non-Hodgikin's lymphoma (NHL) with R-CHOP is classified with relative high risk of febrile neutropenia. The study evaluated the prophylactic effect of pegfilgrastim to reduce the incidence of febrile neutropenia associated with R-CHOP of patient in NHL. And the risk factors associated with the incidence of FN and related events were evaluated. Methods: This retrospective study reviews the Electronic Medical Record of 68 NHL patients who received R-CHOP chemotherapy in single center between September 2013 and August 2014. These patients were classified who receive prophylaxis pegfilgrastim or no prophylaxis. Results: Sixty eight patients received R-CHOP with NHL. In 144 cycles of patients receiving pegfilgrastim, compared with no prophylaxis 178 cycles, had a lower incidence of febrile neutropenia (5.5% vs. 23.6%, p = 0.001), grade 3 or grade 4 neutropenia (14.4% vs. 89.8%, p < 0.001) and neutropenia related events (p < 0.05). The risk of febrile neutropenia after prophylaxis was significantly associated with age ${\geq}65$ (OR: 5.87, 95% CI 1.07-32.27, p = 0.042), $IPI{\geq}3$ (OR: 7.2, 95% CI 1.31-39.6, p = 0.023), S.alb < 3.5 g/dL (OR: 31.01, 95% CI 6.32-152.17, p < 0.0001). In multiple logistic regression analysis, lower baseline serum albumin (OR: 21.1, 95% CI 3.8-116.98, p = 0.001) was significantly associated with occurrence of febrile neutropenia. Conclusion: The study recommends prophylactic pegfilgrastim through risk assessment of febrile neutropenia in patients with non-Hodgikin's lymphoma receiving R-CHOP.

• 한국응급구조학회지
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• 제15권3호
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• pp.57-70
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• 2011

Purpose : The purpose of this study was to reveal some factors of ROSC & survival for cardiac arrests from sport & leisure activities(CASLs). Methods : A retrospective study of the 1,341 out of hospital cardiac arrests(OHCAs) treated by EMS in Gyeonggi Provincial Fire and Disaster Headquarters from January to December in 2008 was conducted. The primary end-point was admission to emergency room. To clarify the factors through comparison of CASLs(n=58) with ROSCs & survivals(n=58), Answer Tree analysis for data mining with the CHAID algorithm was performed and alpha was set at .05. Mean, median, and percentile of time intervals, distances, and age on the 58 CASLs, 75 ROSCs, and 27 survivals(patients admitted to emergency room) were analysed. Results : Fourteen CASLs(24.1%), 41 ROSCs(54.7%), 16 survivals(59.3%) were treated with CPR within 5 min., and only 2 CASLs(3.4%), 11 ROSCs(14.7%), 10 survivals(37.0%) were treated with defilbrillation within 10 min. from arrest. If time recording from arrest to defilbrillation, the patients were classified 81.0%($X^2=9.83$, p=.005) into ROSCs & survivals. And the patients with no history, 100.0%($X^2=5.44$, p=.020). The other patients with no intention, 87.5%($X^2=7.00$, p=.024). Whereas the other patients with intention, treated with CPR after 4 min. from arrest were classified 67.2%($X^2=3.99$, p=.046) into CASLs. Conclusion : CPR within 4 minutes was the most important factor that discriminates between CASLs and ROSCs & survivals to record cardiac arrests-defilbrillation time. CPR within 4 min. from arrest, no history, and no intention were factors for improved ROSC & survival.

• 한국환경복원기술학회지
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• 제11권6호
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• pp.38-48
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• 2008

This study was conducted to evaluate the vegetation structure of community by the phytosociology method, floristic composition table on coast of South Korea. Form 2007 June until November, $2m{\times}2m$ quadrat was established in native Glehnia littoralis in order to record a dominants and coverage, and it drew the profile. It was found out that the mean temperature in the distributed areas for Glehnia littoralis population was $11^{\circ}C$ or more. The flora of the studied area in Glehnia lottoralis community of coastal dune was listed as 100 species. Glehnia lottoralis community of appearance species of Yeonggwanggun Duwori was many most by 44 species. Carex pumila, Carex Kobomugi, Imperata cylindrica var. koenigii, Ischaemum anthephehoroides and Vitex rotundifolia range all over the studied areas. And the vegetation of Glehnia littoralis community was classified into Vitex rotundifolia subcommunity, Ischaemun anthephephoroides subcommunity and Imperata cylindrica var. koenigii subcommunity. Native Glehnia littoralis was classified into preserve area, natural selection area and artificial destruction area. It must preserve native Glehnia littoralis of Goseong, Yeongdeok, Haenam it was ecological important area.

• 한국한의학연구원논문집
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• 제14권1호
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• pp.117-121
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• 2008

Objectives : This study was carried out to investigate vegetation structure of Adenophora remotiflora population found to be distributed in Jeombongsan Danmokryeong. Methods : From 2007 June until November, $2m{\times}2m$ quadrat was established in Adenophora remotiflora community in order to record a dominants and coverage. Results : 1. The vegetation of Adenophora remotiflora community was classified into Astilbe chinensis subcommunity and Calamagrostis langsdodfii subcommunity. Differential species of community was Angelica deacrusica and Lychnis cognata. The Adenophora remotiflora community was found in south face, high of altitude and low slope degree. 2. The value of species diversity ranged from 5.547152 to 10.077886, euenness ranged from 0.779749 to 0.986358 and dominance ranged from 0.013642 to 0.220251. 3. Aconitum jaluense was located at the higher altitudes than those of other species. Lychnis cognata, Lychnis cognata and Pedicularis resupinata was located at the lower altitudes and slope degree than those of other species. Conclusions : The vegetation of Adenophora remotiflora community was classified into Astilbe chinensis subcommunity and Calamagrostis langsdodfii subcommunity. The value of species diversity was low and community was dominated by a large number species. The Adenophora remotiflora community was found in south face, high of altitude and low slope degree.

• Journal of Animal Science and Technology
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• 제54권6호
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• pp.463-469
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• 2012

This study utilized a standardization and cluster analysis technique for the selection and classification of beneficial bacteria. A set of synthetic data consisting of 100 individual variables with three characteristics was created for analysis. The three characteristics assigned to each independent variable were designated to have different numeric scales, averages, and standard deviations. The variables were bacterial isolates at random, and the three characteristics were fermentation products, including cell yield, antioxidant activity of culture, and enzyme production. A standardization method utilizing a standard normal distribution equation to record fermentation yields of each isolate was employed to weight their different numeric scales and deviations. Following transformation, the data set was analyzed by cluster analysis. The Manhattan method for dissimilarity matrix construction along with complete linkage technique, an agglomerative method for hierarchical cluster analysis, was employed using statistical computing program R. A total of 100 isolates were classified into groups A, B, and C. In a comparison of the characteristics of each group, all characteristics in groups A and C were higher than those of group B. Isolates displaying higher cell yield were classified as group A, whereas those isolates showing high antioxidant activity and enzyme production were assigned to group C. The results of the cluster analysis can be useful for the classification of numerous isolates and the preparation of an isolation pool using numerical or statistical tools. The present study suggests that a simple technique can be applied to screen and select beneficial microbes using the freely downloadable statistical computing program R.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제14권4호
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• pp.275-282
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• 1992

Maxillofacial war injures is specific representative of severe hard and soft tissue defect. This type of injuries were different from the trauma because it may be fatal. The purpose of this study was to evaluate the injury type base on the retrograde medical record in the 104 patients from Feb. 1991 to Aug. 1992 in Korea Veterans Hospital. The obtained results were as follows. 1. Among 104 cases, 51 cases(49.0%) were classified as mandibular defects only, and 53 cases (51.0%) were classified as maxillary with mandibular defect (combined). 2. The etiologic factors of injury were gunshot, artillery and grenade or shell: 33 cases, 14cases, and 10 cases respectively in Korea War, 19 cases, 5 cases, and 8 cases respectively in Vietnam War. 3. In 57 cases of mandibular partial defect, the angle area showed the highest frequencies, 18 cases(31.6%). 4. In 42 cases of mandibular segmental defect, the area between the 1st molar and the ascending ramus showed the highest frequencies. 17 cases(40.4%), and almost all cases were unilateral defect (40 cases, 95.0%) 5. Reconstruction method performed for segmental mandibular defect were wire or plate(15 cases, 35.7%) and soft tissue closure only(12 cases, 28.7%), respectively.

• 한국산학기술학회논문지
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• 제11권1호
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• pp.361-367
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• 2010

이 연구는 2007년 1월 1일부터 동년 12월 31일까지 1년간 대전 소재 일개대학병원에서 수술 취소된 총 146명의 환자를 대상으로 하였으며, 계획된 수술의 취소율을 극소화하여 병원 경영의 합리적 개선과 진료 만족도를 증가시키고자하는 목적에서 이루어졌다. 조사대상자의 성별 분포를 보면, 남자 56.8%, 여자 43.2%로 여자보다 남자가 높은 분포를 보였다. 수술 취소 원인을 살펴보면 수술취소까지 이르지 않을 수 있었던 사항과 불가항력적으로 수술을 취소해야 할 사항으로 나눌 수 있는데, 이런 분류를 통해 전체 수술 취소 사유 중 60.0%는 예방이 가능했던 사항이라고 했다. 본 연구결과를 기초로 타 연구자와 병원관리자에게 수술 취소율 감소 개선을 위한 정책방향의 수립을 제언한다.

• Journal of Preventive Medicine and Public Health
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• 제52권6호
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• pp.377-383
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• 2019

Objectives: Self-reported disease history is often used in epidemiological studies. In this study, we acquired the hospital records of subjects who self-reported stroke or myocardial infarction (MI) and evaluated the validity of the participants' self-reported disease history. We also determined the level of agreement between specialists and non-specialists. Methods: Among the participants in the Health Examinees study, 1488 subjects self-reported stroke or MI during 2012-2017, and medical records were acquired for the 429 subjects (28.8%) who agreed to share their medical information. Each record was independently assigned to 2 medical doctors for review. The records were classified as 'definite,' 'possible,' or 'not' stroke or MI. If the doctors did not agree, a third doctor made the final decision. The positive predictive value (PPV) of self-reporting was calculated with the doctors' review as the gold standard. Kappa statistics were used to compare the results between general doctors and neurologists or cardiologists. Results: Medical records from 208 patients with self-reported stroke and 221 patients with self-reported MI were reviewed. The PPV of self-reported disease history was 51.4% for stroke and 32.6% for MI. If cases classified as 'possible' were counted as positive diagnoses, the PPV was 59.1% for stroke and 33.5% for MI. Kappa statistics showed moderate levels of agreement between specialists and nonspecialists for both stroke and MI. Conclusions: The validity of self-reported disease was lower than expected, especially in those who reported having been diagnosed with MI. Proper consideration is needed when using these self-reported data in further studies.

• 식물분류학회지
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• 제42권3호
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• pp.207-210
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• 2012

한국 미기록 식물 영주갈고리 Hylodesmum laxum (Candolle) H. Ohashi & R. R. Mill subsp. laxum를 보고한다. 영주갈고리는 동남아시아에 널리 분포하는 식물로 우리나라에서는 제주도 서귀포시 상록수림에서 최초로 발견되었다. 갈고리속(Hylodesmum H. Ohashi & R. R. Mill)은 도둑놈의갈고리속 Podocarpium절 (Desmodium sect. Podocarpium Benth)에서 속으로 최근 분리, 승격되었다. 기존의 도둑놈의갈고리속에 속하는 한국산 중 2종을 제외한 나머지는 갈고리속으로 분류된다. 한국산 갈고리속 종의 검색표와 분류군 목록을 작성하였다.

• 한국기록관리학회지
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• 제10권1호
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• pp.169-197
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• 2010

본 연구는 형사사건기록의 분류방안을 마련해 보는데 연구의 목적을 두었다. 형사사건기록의 유형 및 특성을 파악하여 형사사건기록이 사안파일의 한 유형임을 밝히고, 이후 현재 검찰청에서 형사사건기록의 분류 현황 및 문제점을 짚어 보았다. 새로운 형사사건기록의 분류원칙으로 사건단위별 분류를 기본으로 하되, 업무절차에 따른 단계별 분류체계 방법을 제안하였다. 이는 향후 형사사건기록이 전자기록 관리체계로 전환되었을 경우의 분류체계로서, 단계별 분류체계에 대한 개념은 MoReq 2의 Workflow 개념을 도입한 것이다.