• Title/Summary/Keyword: classification for oriental medicine

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Simultaneous Determination of (-)-Menthone and (-)-Menthol in Menthae Herba by Gas Chromatography and Principal Component Analysis

  • Kim, Jung-Hoon;Seo, Chang-Seob;Shin, Hyeun-Kyoo
    • Natural Product Sciences
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    • v.16 no.3
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    • pp.180-184
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    • 2010
  • The simple and accurate method was established for the simultaneous determination of (-)-menthone and (-)-menthol in Menthae herba obtained from Korea and China. A quantitative analysis was performed with a gas chromatography-flame ionization detector and reference compounds were separated on a capillary HP-Innowax column (30 m $\times$ 0.23 mm, 0.50 ${\mu}m$, Agilent, MA, USA). The correlation coefficients of the compounds showed good linearity ($r^2$ > 0.9997) over the linear range. The precision, repeatability and stability showed less than 1.7% of relative standard deviation (RSD) values for two compounds. Recovery rates were within the range of 95.72 - 103.76%. The method was applied successfully to analyze 15 samples of Menthae herba and achieved sufficient and specific separation of reference compounds. The principal component analysis (PCA) exhibited the classification of 15 samples according to their locations of origin.

Preliminary Study to Establish a Decision Support System in Sasang Constitutional Medicine with Clinical Data (사장체질 의사결정시스템 구축을 위한 체질 진단 자료를 이용한 예비연구)

  • Jin, Hee-Jeong;Moon, Jin-Seok;Go, Seong-Ho;Ku, Im-Hoi;Lee, Si-Woo;Lee, Do-Heon;Song, Mi-Young;Kim, Jong-Yeol
    • Korean Journal of Oriental Medicine
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    • v.13 no.2 s.20
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    • pp.75-81
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    • 2007
  • The need for the study of the revealing Sasang constitution at scientific term is increasing as the application of this discipline to the patient produces more accurate result. To obtain scientific evidence of Sasang constitution, it is crucial to analyze accumulated clinical information and associate them to the biological indices that may classify Sasang constitution. Thus, the analysis of clinical information is the most important stepping stone to go toward to the stage of developing model and decision support system (DSS) for classifying Sasang constitution. This study is a preliminary analysis of 1,109 samples collected with 171 clinical indices. To find meaningful clinical indices for classifying Sasang constitutional medicine, we applied decision tree model for them. The skin of 66.5% within whole Taeeumin is thick and non feeble. In the case of 69.8% within whole Soyangin, the skin is non feeble and slippery. In the case of 64.4% within whole Soeumin. they have feeble skin. Therefore, the property of skin can be suggested to be more important than any other index for the classification of Sasang constitution.

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Clinical Investigation of Survey and Test in Korean Oriental Pediatrics (한방소아과 설문지 및 검사에 관한 임상현황연구)

  • Hwang, Young-Jun;Kim, Ki-Bong;Min, Sang-Yeon;Kim, Jang-Hyun
    • The Journal of Pediatrics of Korean Medicine
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    • v.22 no.1
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    • pp.25-34
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    • 2008
  • Objectives The purpose of this study is to investigate whether Korean oriental pediatrics hospitals are using their feedback surveys to improve their medical conditions. Methods We selected 24 oriental medicine university hospitals and sent surveys to investigate. 15 of those surveys were analyzed. Results The results were classified as follows; Only 9 of university hospital said that they are currently using their feedback surveys to improve their services. Question for asking the purpose of doing their feedback surveys, 58.3% of hospital responded to get some information for diagnosis, 25% of them said to see the progress of treatment of specific disease, and 16.7% answered for using their data to the further studies. The question about the reason why hospital were need to make these feedback surveys, 46.2% of them answered to apply better service, 38.4% of them said to post medical journal. The question for asking what do oriental medical hospitals check from feedback surveys, 40% of them said they check Ryodoraku, 33.3% was pulse diagnostic apparatus, EAV(Electro-puncture According to Voll) was 26.7%. The classification according to purpose of test resulted as follows; information for diagnosis was 48.1%, the progress of a disease was 37.3%. In addition oriental medical test there were blood test, radiological test, brain waves test, Hair Tissue Mineral Analysis(HTMA), ultrasonic test, body composition analysis. Conclusions Further clinical research is necessary for improvement of using the feedback survey effectively.

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The Study on The Validity of "Questionnaire of Sasang Constitution Classification(I)" (사상변증내용(四象辯證內容) 설문조사지(設問調査紙)(I)의 타당화(妥當化) 연구(硏究))

  • Lee, Eui Ju;Ko, Byung Hee;Song, Il Byung
    • Journal of Sasang Constitutional Medicine
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    • v.7 no.2
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    • pp.89-100
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    • 1995
  • This study was conducted for the purpose of finding out an objective classification method for Sasang Constitutional medicine, which divides people into 4 groups of constitution and presents comprehensively physiology, pathology, diagnosis, therapy and recuperation regarding each constitution. Questionnaire of Sasang Constitution Classification(I) was administered to 328 inpatients at Kyung Hee Oriental Medicine Hospital. Data was collected during 10 months from June 1994 to Mar. 11, 1995. For the purposes of this study, the collected data was analyzed by crosstabs, variation analysis, and discrimination analysis. The analyzing program was SPSS PC+V4.0. For the purposes of this study, the collected data was analyzed by crosstabs, cariation analysis, and discrimination analysis. The analyzing program was SPSS PC+V4.0. The results were as follows : 1. There was significant differences of each group scales through variation analysis. The questions of each group had Sasang constitutional diagnostic discrimination abilities 2. The diagnostic discrimination abilities(Hit-ratio=56.10%) of the Questionnaire for Sasang Constitution Classification(I) were found to have over 20% improvement than the propotional chance criteria(33.3%), Especially, Hit-ratio for $So{\breve{u}}m$-In(63%) was higher than that of SoYang-In(55%) and $Ta{\breve{e}}um$-In(56.3%). 3. Through discrimination analysis on good questions of each group, the diagnostic discrimination abilities of the Questionnaire for Sasang Constitution Classification(I) was 57.93%. 4. This would be on the ground that the Questionnaire for Sasang Constitution Classification(I) could be used as a tool for Sasang constitution classification.

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Study of on Academic Stress Responses According to Sasang Constitutions of Oriental Medicine College Students (한의과대학생의 사상체질별 학업스트레스 연구)

  • Chang, Jun-Yong;Kim, Kyoung-Shin;Kim, Byoung-Soo
    • Journal of Oriental Neuropsychiatry
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    • v.23 no.3
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    • pp.77-88
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    • 2012
  • Objectives : This study was founded to identify the differences of stress responses, according to Sasang Constitutions (the Taeyangin, Taeumin, Soyangin and Soumin) of highly stressed oriental medicine college students. Methods : The subjects were 76 students who majored in oriental medicine. We processed 'University students Stress Scale', and 'Medical Stress Scale'. We selected 30 students who stressed higher than average. We then processed 'QSCC II (Questionnare for the Sasang Constitution Classification II)' and 'Scale for the Stress Response'. Collected data was analyzed with the SPSS 19.0 for windows statistical program. Results : The university students stress score of oriental medicine students was 1.97 that was higher than the other college students. The medical stress score was 2.77, which was similar with other medical college students. The symptoms of stress score was 2.53, which was higher than the others. Particularly, the depressive syndrome and rage syndrome were highly ranked. The frequently appearing symptoms of each type of Sasang Constitutions (the Taeyangin, Taeumin, Soyangin and Soumin) showed as follows. The Soyangin's symptoms of stress showed in order of Anxiety, Depression, and Emotional irritability. The Soumin's symptoms of stress showed in order of Depression, Emotional irritability, and cognitive disorganization. The Taeumin's symptoms of stress showed in order of Anxiety, Depression, and Emotional irritability. However, there was were no significant differences among the results of each constitution. Conclusions : The results show that oriental medicine students have as much stress as other medical college students and there was tendency of showing different patterns of stress response, according to Sasang Constitution, but it's not significantly different.

Study on Dan Dong Ten Lessons (Dan Dong Exercise) among Healthcare Qi Gong Methods for Children (소아(小兒)의 양생기공(養生氣功) 중(中) 단동치기(檀童治基) 십계훈(十戒訓) (단동십계체조(檀童十戒體操))에 관(關)한 연구(硏究))

  • Jeon, Chun-San;Kim, Jang-Hyun
    • The Journal of Pediatrics of Korean Medicine
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    • v.22 no.1
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    • pp.49-57
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    • 2008
  • Objectives As children are physiologically and pathologically sensitive and likely to have trouble developing respiratory and the digestive system, it is necessary for them to improve and adapt to their digestive and respiratory capacity slowly. Although they desperately need to practice Healthcare Qi Gong as they get older, few studies have been conducted about that. While collecting materials on child Healthcare Qi Gong, In order to study more about Dan Dong Ten Lessons, medical researchers and children's parent should be more concerned to these studies. The purpose of this study was to understand Dan Dong Ten Lessons through research on children's healthcare Qi Gong. Methods This study was prepared through collecting data from past oriental medicine studies. Through the examination of Chinese medicine books and scientific studies about Dan Dong Ten Lessons and healthcare Qi Gong, Dan Dong Ten Lessons was classified and systemized. Results Dan Dong Exercise among the contents of children's healthcare Qi Gong was classified through the classification and theorization of Dan Dong Ten Lessons, although the classification and development of children's Qi Gong methods should have been carried out in the area of korean medicine, but it was not easy to find the references. Conclusions Dan Dong Ten Lessons is a song and Qi Gong therapy for children. It also teaches children how to live their life, guides them in the right direction for their life. Therefore, it should be developed academically and practically, so that it can pass down to the next generation as traditional heritage.

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Development of the pulse analyzing system using FBG (FBG를 이용한 맥진 시스템 개발)

  • Jeon, Young-Ju;Lee, Jeon;Ryu, Hyun-Hee;Lee, Jae-Hoon;Lee, Si-Woo;Kim, Jong-Yeol
    • Korean Journal of Oriental Medicine
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    • v.13 no.3
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    • pp.105-110
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    • 2007
  • This work reports the pulse diagnosis system using FBG sensors which can display pulse signals detected while oriental medical doctors are conducting pulse diagnoses and simultaneously pressing the sensors by three fingers. Each optical fiber has five FBG sensing units fabricated in 2 mm width and 2 mm inter-sensor spacing. Three optical fibers with the FBG units in the parallel line configuration are then placed on each finger-pressing region and thus overall 9 fibers are used for the pulse measurements on the so-called "chon", "gwan", and "ch대k". A fixture holding the optical fiber arrays is able to adjust the height of the FBG sensing units while placing the fibers on the wrist. The pulse signals detected by the FBG sensors from chon, kwan, and chuk have been analyzed using 4 channel spectrum analyzer connected to the optical fibers. The measured pulse signals exhibit variations due to the nonuniform pressure distributions applied. resulting in the differences in the detected pulse signals between fiber lines. However. this work is the first step towards objective and quantitative analyses of the pulse diagnosis in oriental medicine which has traditionally been performed on subjective basis. Future works will be devoted to improving sensor stability, developing the way applying pressure and algorithms reporting the objective classification of the pulse status from systemic measurements using the sensors instead of relying on the clinicians' diagnoses subjectively performed. A successful pulse diagnosis system emerging in the future is expected to contribute to education as well as promoting pulse diagnosis in oriental medicine to the scientific research area.

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Analysis on Research Trend of Studies Related with Scutellariae Radix in Korea (황금(黃芩)에 관한 국내 연구 동향에 관한 소고)

  • Kim, Kang-San;Kim, Lae-Hee;Rhee, Yun-Jin;Lee, Su-Hyoun;Choi, Ji-Hye;Ko, Ha-Neul
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.25 no.6
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    • pp.1095-1101
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    • 2011
  • Scutellariae Radix has been used as a traditional medicine for anti-oxidant, anti-inflammatory, anti-allergic function. But most study methods were restricted to in vitro and in vivo. Therefore to perform for clinical trials further for a new natural drug development is necessary and this study will be used as a basis for it. The studies selected from domestic academic database included the following key words; '황금', '黃芩', 'skullcap', 'Scutellariae Radix', 'scutellaria baicalensis' and considered were those published from 1990 to July, 2011. All 1080 studies were found to include the keywords related to the study subjects either in their title of contents or abstracts. and 298 studies were finally selected as subjects for this study. 243 studies among 293 studies were published between 2000 to 2011. Classification was proceeded according to study subjects as followed; anti-Inflammatory effect and antiallergic and antihistamin effect(66), antibacterial and antivirus effect(61), antioxidant effect(51), neuronal cell apoptosis and neuronal cell protective effect(22), liver cell protective effect(20). According to method type of study, 194 studies practicing in vitro, 60 studies practicing in vivo, 37 studies practicing in both. and 5 studies on documentary records. Most study methods were restricted in vitro and in vivo. For developmenting of function of anti-inflammatory effect and antiallergic, antihistamin effect & atopic dermatitis effect, antibacterial and antivirus effect, antioxidant effect, case report on various fields and multicenter clinical trials is necessary.

Evaluation of Health Information on Internet Sites Dealing with Oriental Obstetrics & Gynecology about Menstrual Pain (월경통으로 검색한 한방부인과 관련 인터넷사이트의 건강정보에 대한 평가)

  • Youn, In-Hwan;Cho, Han-Baek;Kim, Song-Baeg;Choi, Chang-Min;Choi, Chul-Won;Ryu, Sung-Won
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.2
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    • pp.188-195
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    • 2007
  • Purpose: The purpose of this study was to analyze current status of the web-sites dealing with oriental obstetrics & gynecology in the internet, and to evaluate their quality and confidence of health information. Methods: It was selected 54 local sites by searching for such key words as menstrual pain. The evaluation tool consisted of six major classification (Content, Authorship, Purpose, Functionality, Feedback and Privacy). Results: In the evaluation of web-sites, the lowest and the highest scores were 7 and 19 out of 26, and the average score was 13.94. The scores of Purpose, Content, Feedback were higher than the average, but the scores of Authorship, Functionality, Privacy were lower than the average. Conclusion: There is a need to develop a high-quality information about latest, confidence, authorship of documents, and to prevent a exposure of privacy.

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Genetic Analysis study of Sasang Constitution Classification by RFLP (RFLP법을 이용한 사상체질의 유전적 분석 연구)

  • Cho, Dong-Wuk;Cho, Hwang-Sung
    • Journal of The Association for Neo Medicine
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    • v.2 no.1
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    • pp.25-33
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    • 1997
  • In Sasang medicine, humen are classified into four constitutions which are Taeyang, Soyang. Taeum and Soum. Depending on each different constitution, the clinical and pharmacological application for the same disease might be different. In this study, genomic DNA of different constitutions(Taeum, Soyang and Soum) were analyzed by Restriction Fragment Length Polymorphism(RFLP) to provide scientific and objective references for Sasang classification. The DNA polymorphism for each constitution detected as differences in the length of DNA fragments, after digestion with restriction enzyme Hae III, was investigated using YNH24 as DNA probe. The allele size of Taeum, Soyang and Soum group detected by YNH24 ranged from 1.3 to 3.8 kb, 1.5 to 3.9 kb and 1.3 to 4.6 kb, respectively. However, the allele size distribution of YNH24 loci of different constitutions was shown to be too variable to be classified as 3 different constitution groups investigated. For further study, it is suggested that the number of each constitution samples for RFLP analysis should be increased and statistical analysis of the allele size distribution should be carried out.

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