• The korean journal of orthodontics
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• v.50 no.2
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• pp.98-107
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• 2020

Objective: The aim of this study was to compare posterior tooth inclinations, occlusal force, and contact area of adults with different sagittal malocclusions. Methods: Transverse skeletal parameters and posterior tooth inclinations were evaluated using cone beam computed tomography images, and occlusal force as well as contact area were assessed using pressure-sensitive films in 124 normodivergent adults. A linear mixed model was used to cluster posterior teeth into maxillary premolar, maxillary molar, mandibular premolar, and mandibular molar groups. Differences among Class I, II, and III groups were compared using an analysis of variance test and least significant difference post-hoc test. Correlations of posterior dental inclinations to occlusal function were analyzed using Pearson's correlation analysis. Results: In male subjects, maxillary premolars and molars had the smallest inclinations in the Class II group while maxillary molars had the greatest inclinations in the Class III group. In female subjects, maxillary molars had the smallest inclinations in the Class II group, while maxillary premolars and molars had the greatest inclinations in the Class III group. Occlusal force and contact area were not significantly different among Class I, II, and III groups. Conclusions: Premolar and molar inclinations showed compensatory inclinations to overcome anteroposterior skeletal discrepancy in the Class II and III groups; however, their occlusal force and contact area were similar to those of Class I group. In subjects with normodivergent facial patterns, although posterior tooth inclinations may vary, difference in occlusal function may be clinically insignificant in adults with Class I, II, and III malocclusions.

• The korean journal of orthodontics
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• v.54 no.3
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• pp.171-184
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• 2024

Objective: This study aimed to determine the maxillary and mandibular basal bone regions and explore the three-dimensional positional relationship between the dentition and basal bone regions in patients with skeletal Class I and Class II malocclusions with mandibular retrusion. Methods: Eighty patients (40 each with Class I and Class II malocclusion) were enrolled. Maxillary and mandibular basal bone regions were determined using cone-beam computed tomography images. To measure the relationship between the dentition and basal bone region, the root position and root inclination were calculated using the coordinates of specific fixed points by a computer program written in Python. Results: In the Class II group, the mandibular anterior teeth inclined more labially (P < 0.05), with their apices positioned closer to the external boundary. The apex of the maxillary anterior root was positioned closer to the external boundary in both groups. Considering the molar region, the maxillary first molars tended to be more lingually inclined in females (P = 0.037), whereas the mandibular first molars were significantly more labially inclined in the Class II group (P < 0.05). Conclusions: Mandibular anterior teeth in Class II malocclusion exhibit a compensatory labial inclination trend with the crown and apex relative to the basal bone region when mandibular retrusion occurs. Moreover, as the root apices of the maxillary anterior teeth are much closer to the labial side in Class I and Class II malocclusion, the range of movement at the root apex should be limited to avoid extensive labial movement.

• The korean journal of orthodontics
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• v.15 no.2
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• pp.229-237
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• 1985

The Purpose of this study was to investigate the differences in soft tissue characteristics according to the dental or skeletal dysplasia. For this purpose, lateral cephalogram of 153 children (Hellman dental age IIIB: control group 32, Angle CIII. div. 1 malocclusion group 55, Angle Cl III group 66) were traced and measured. For these measurements, following conclusions were made. 1. FH A, FH Sn, FH UL, AA' of the Class III group were thicker than those of the normal and Class II group, but FH B, FH LL, BB' of the Class III group were not significantly different from those of the normal group. 2. FH B, FH LL, BB' of the Class II group were thicker than those of the normal and Class III group, but FH A, FH Sn, FH UL, AA' of the Class II group were not significantly different from those of the noraml group. 3. Ans-Sn, FH P were not significantly different in three groups, while PP' of the Class III group was thicker than those of the other groups. 4. The lower lips of the Class II group were more anterioly everted with respect to the lower incisor inclination than those of the other groups. 5. The severity of skeletal dysplasia was partly camouflaged by the soft tissue.

• Journal of Yeungnam Medical Science
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• v.4 no.1
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• pp.151-156
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• 1987

A 25 year and 7 month old man patient who had Angle's classII division 2 malocclusion combined with anterior crowding of upper & lower part was treated by bioprogressive mechanism. After setting our objectives through the use of V.T.O., we programmed a sequence of mechanics. The possible objectives of treatment in the classII division 2 malocclusion can be listed as follows. 1) Relief of crowding & irregularities. 2) Relief of anterior gingival trauma & correction of interincisal inclination. 3) Correction of buccal segment relationship. We'd applied the classII intermaxillary elastics, Quad helix, utility arch wire and sectional arch wire in order to achieve anticipated objectives. As compared with pre & post treatment cephalogram, the result accomplished by this mechanics showed to us that interincisal angle was improved and favorable molar relationship was achieved.

• The korean journal of orthodontics
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• v.52 no.6
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• pp.432-438
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• 2022

Objective: To compare crown-root angulations of the permanent maxillary anterior teeth in skeletal Class I, Class II, and Class III Korean malocclusion patients using cone-bean computed tomography (CBCT) images. Methods: Sixty CBCT images were collected from orthodontic patients archive based on skeletal Class I (0˚< A point-nasion-B point angle [ANB] < 4˚), Class II (ANB ≥ 4˚), and Class III (ANB ≤ 0˚) to have 20 samples in each group. Mesiodistal crown-root angulation (MDCRA) and labiolingual crown-root angulation (LLCRA) were evaluated after orientation of images. Crown-root angulations were compared among Class I, Class II, and Class III groups and among the maxillary anterior teeth in each group. Results: LLCRAs of the maxillary central incisor and the lateral incisor were significantly lower in Class III group than those in Class I group. However, those of the canine showed no significant differences among groups. MDCRAs of the maxillary anterior teeth did not significantly differ among groups either. Conclusions: Our results suggest that skeletal Class III malocclusion might affect LLCRA of the maxillary incisors, especially the central incisor.

• The korean journal of orthodontics
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• v.18 no.1 s.25
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• pp.89-104
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• 1988

This study was performed to investigate the relationships between the EMG activity of the masticatory muscles in Angle's Class II div. 1 malocclusion and normal occlusion. This study was ranged from age 12 to 14 year-old for 30 male subjects: 15 subjects were Angle's Class II div. 1 malocclusion, and 15 subjects were normal occlusion with acceptable profile. Their cephalometric measurement were analyzed, and the EMG recordings from the anterior temporal, posterior temporal, masseter, and orbicularis oris muscles were analyzed during rest position, mastication of peanuts, and swallowing. All data was recorded and statistically processed with the VAX-11/780 computer system. The results were as follows: 1. The activity of muscles at rest was highest in the posterior temporal muscle with normal occlusion, as well as in those with Class II div. 1 malocclusion, and the posterior temporal muscle activity of Class II div. 1 malocclusion was higher than that of normal occlusion. 2. During mastication, all muscle activities of Class II div. 1 malocclusion were recorded lower than those of normal occlusion, and the activity of the anterior temporal muscle was higher than that of the posterior temporal muscle in both types of occlusion. 3. As for the activity in orbicularis oris muscle, it was greater in opening phase than in closing phase during chewing cycle with both types of occlusion. 4. During swallowing, the activities of the anterior temporal, masseter, and orbicularis oris muscles of Class II div. 1 malocclusion were recorded lower than those of normal occlusion.

• Journal of Chest Surgery
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• v.28 no.5
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• pp.443-446
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• 1995

The present study was designed to determine whether cyclosporine A inhibits Major Histocompatibility Complex Class II antigen[MHC II expression in the allograft rat heart myocardium. In this rat allograft study we also tried to elucidate whether CSA inhibits MHC II in a dose dependent way. Hearts were isolated from LBN rats weighing 200-250 grams and heterotopically transplantated into the abdomen of weight-matched ACI rats. The ACI rats were randomly assigned to one of the three experimental groups according to cyclosporine dosage: {1}control [no CSA , n=6 {2}CSA 5 mg/day , n=5 {3}CSA 10 mg/day, n=5. The transplanted hearts were harvested 5 days postoperatively and analyzed. MHC II expression was detected by indirect immunoperoxidase staining and quantified via computer image analysis system. The % positive area reading was obtained in each slide [50 areas per group and compared to other groups. Significant differences were noted between three groups [p<0.05 . We conclude that CSA inhibits MHC II in heterotopically transplanted allograft rat heart in a dose dependent way.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.27 no.2
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• pp.66-74
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• 2018

Composite resin restoration on class II cavities is a challenging procedure since it is tough to replicate proper contact, the natural shape of the tooth, etc. Moreover, it is not familiar with the procedure and tools for this specific situation, neither. Nowadays the patients, however, request more and more composite restorations which are relatively quick and more esthetic. In this case report, the class II composite resin restoration procedure is illustrated step by step. Every step must be considered its final consequence thoroughly. In this approach, we can minimize the finishing procedure and save our effort and time.

• Biomolecules & Therapeutics
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• v.19 no.1
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• pp.77-83
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• 2011

Sulforaphane is an isothiocyanate found in cruciferous vegetables that has been reported to be an effective cancer preventive agent inducing growth arrest and/or cell death in cancer cells of various organs. This paper reports that sulforaphane exerts immunomodulatory activity on the MHC-restricted antigen presenting function. Sulforaphane efficiently increased the class II-restricted presentation of an exogenous antigen, ovalbumin (OVA), in both dendritic cells (DCs) and peritoneal macrophages in vitro. The class II-restricted OVA presentation-enhancing activity of sulforaphane was also confirmed using mice that had been injected with sulforaphane followed by soluble OVA. On the other hand, sulforaphane did not affect the class I-restricted presentation of exogenous OVA at concentrations that increase the class II-restricted antigen presentation. At a high concentration ($20\;{\mu}M$), sulforaphane inhibited the class I-restricted presentation of exogenous OVA. Sulforaphane did not affect the phagocytic activity of the DCs, and the cell surface expression of total H-$2K^b$, B7-1, B7-2 and CD54 molecules, even though it increased the expression of I-$A^b$ molecules to a barely discernable level. These results show that sulforaphane increases the class II-restricted antigen presenting function preferentially, and might provide a novel insight into the mechanisms of the anti-cancer effects of sulforaphane.

• The korean journal of orthodontics
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• v.25 no.3 s.50
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• pp.299-310
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• 1995

The purpose of this study is to know about the positional change of second molar when orthodontic treatment is performed. To know about it, we andlysed cephalogram pre. and post treatment for 54 adult patients who werefinished orthodontic treatment by banding to the first molar and classify them into 4 groups Class I extraction group 15, Class I nonextraction group 12, Class II group 13, class Class III group 14. The following conclusions were obtained : 1. In the extraction group of Class I , mandibular second molar showed less extrusion and mon distal inclination than first moarl. But maxillary second molar showed more or less extrusive and mesial inclination to much the same degree of first molar. 2. Inthe non-extractio group of Class I, mandibular second molar in intrusive to first molar, it showed smilar distal inclination to first molar. But maxillary second molar is extrusive similarly to first molar. 3. In the group of Class II , mandibular second molar is less extrusive than first molar and maxillary second molar is more extrusive than first molar. 4. In the group of Class III, mandibular second molar showed similar extrusion to first molar and more distal inclination than first molar. But maxillary second molar showed less extrusion than first molar. 5. A comparision of the positional change of second molar among groups : The change of distance from FH plane to funcation point of maxillary second molar is the difference between Class I extraction group and Class II group, Class I extraction group and Class III group. The change of maxillary second molar to palatal plane and occlusal plane is the difference between Class I extraction group and Class III group. And the change of distance from mandibular plan to furcation point of mandibular second molar is difference between Class I extraction group and non-extraction group, Class I non-extraction group and Class II group, Class I non-extraction group and Class III group. But the change of angle of mandibular second molar to mandibular plane and occlusal plane is make no difference in among groups.