• The Journal of Korean Medicine
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• v.38 no.2
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• pp.1-6
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• 2017

Objectives: Natural environment therapy is considered as an option for atopic dermatitis. This study was aimed to examine the beneficial effects of natural environment therapy among patients with atopic dermatitis who have moved in an atopy-free village. Methods: The questionnaire-based survey was conducted from parents of 20 children with atopic dermatitis (12 male and 8 female, median age 8 years, ranging from 6 to 13 years). The questionnaire consisted of 10 questions for the changes of two typical symptoms of pruritus and sleeping difficulty after moving into an atopy-free village. Results: 75.0% and 88.9% of patients have a family history (at least one parent and one of siblings respectively) of allergic disorders. The median staying period of patients was 27.6 months (ranging from 2 to 55 months). The score indicating pruritus was significantly improved from $6.2{\pm}2.8$ into $4.8{\pm}1.8$ (p<0.05), and sleeping difficulty was also improved from $5.7{\pm}2.9$ into $4.3{\pm}2.1$ (p<0.05) too. Conclusions: This study suggests that the natural environmental therapies could be a choice for patients with atopic dermatitis, which should be studied further for their scientific evidence and mechanisms.

• Journal of Sasang Constitutional Medicine
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• v.14 no.2
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• pp.69-77
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• 2002

Purpose: Atopic dermatitis, which is one the prevalent allergic diseases in toddlers and adolescent population, has not been treated with Sasang Constitutional Medicine due to the limitation of constitution differentiation in children. This study was aimed to examine the effect of treatment for atopic dermatitis with Sasang Constitutional Medicine. Method: Forty-three patients over age 3 who were diagnosed with atopic dermatitis by the criteria of Hanifin and Rajka were participated in this study from August, 2001 thru May, 2002 at the Pohang Oriental Medicine Hospital, Kyungsan University. Result: 1. Soyangin showed the highest proportion of 79% of the sample. 2. The symptom of the disease by patients' constitution according to the degree of affected skin and itching was severe in Soyangin, and mild in Soeumin 3. For treatment 9 kinds of prescription regimen were given; Yangkyuksanhwatang was mostly used for Soyangin followed by Hyungbangsabaksan. Hayngsayangwetang and Galgunhaegitang were prescribed for Soeumin and Taeumin, respectively. 4. The treatment effect was found in 84% (n=36) of the patients markedly. Six out of seven who showed no progress were Soyangin. Conclusion: The treatment based on the constitution differentiation and prescription of the Sasang Constitutional Medicine was effective for the symptom alleviation in a short term period in atopic dermatitis. Further clinical study is needed to prove the effect of Sasang Constitutional Medicine in a larger sample and various diseases.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.23 no.3
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• pp.122-137
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• 2010

Objective : Atopic dermatitis (AD) in children may profoundly affect the quality of life (QOL), and also cause financial burden, to the families of those suffering from this ailment. The aim of our study was to examine the quality of life and the financial burden of atopic dermatitis in children and their families to evaluate this relationship with the degree of AD. Methods : 37 infant and child atopic dermatitis patients were included and evaluated using the SCORing of Atopic Dermatitis (SCORAD) Index and Eczema Area and Severity Index (EASI). Patients and carers were asked to fill in the questionnaires about their quality of life and financial costs during the past year. Data about sleep disturbance and pruritus were also obtained. Pearson's correlation was used for statistical analysis. Results : 1. The mean score of Children's Dermatology Life Quality Index (CDLQI) was $10.52{\pm}4.82$, Infants' Dermatologic Quality of Life (IDQOL) was $8.21{\pm}3.95$. 2. The mean score of Family Dermatology Life Quality Index (FDLQI) was $13.30{\pm}5.72$, Dermatitis Family Impact (DFI) was $12.5{\pm}4.98$. 3. By analyzing the questionnaire, the monthly average cost was determined to be 730,800 won for each patient : the direct cost was 283,500 won, and the indirect cost was 447,300 won. 4. By analyzing the correlation between the severity of AD and QOL, subjective SCORAD were significantly and positively correlated with QOL(IDQOL, FDLQI, DFI, CDLQI). 5. By analyzing the correlation between the severity of AD and any economic impact, EASI were significantly and positively correlated with the direct cost. Conclusion : The above results show that the QOL of the patients and carers is significantly related to their disease severity. Atopic dermatitis patients pay an average of 730,800 won a month, and the economic impact on the patients is significantly related to their disease severity. The CDLQI, IDQOL, FDLQI and DFImay potentially be of value to help in the appropriate management of AD and can be used as an added measurement in clinical trials involving AD management.

• Journal of Korean Biological Nursing Science
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• v.11 no.1
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• pp.77-84
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• 2009

Purpose: This study was performed to investigate outbreak, treatment, and lifestyle in children with atopic dermatitis (AD) for developing a health promotion education program. Method: Data were collected from 2,920 children with AD in preschool and elementary schools in K city. Result: The majority of children (43.75%) were onset in less than 1 yr after the birth. The locations of skin lesion were face, extension of extremities, and flextion of extremities, neck and trunk. The types of treatment were complement therapies, and medical treatment such as pediatrics and dermatology. Their parents chose a type of treatment for their children. Of complement therapies, the most common type was aroma oil. Herbal medicine was the most eating type among complement therapies. In lifestyle, the preferred bathing method was shower. In applying moisturizer, the most common time was within 3 min after bath. The highest frequency of taking instant/processed diet was 1-2 times per week and the most preferred type was pork. Conclusion: A Health promotion educational program with AD in preschool and elementary school children should included a specificity of disease, the recent treatment guideline, life therapy and evidenced complement therapy by child and family unit for the promotion of their health.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.3
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• pp.180-190
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• 2014

Background and Objective : Atopic dermatitis is a type of dermatitis, an inflammatory, relapsing, non-contagious and itchy skin disorder and affecting up to 30% of children in the Korea. In this study, Huini-san, which is mentioned in Shanghanlun(傷寒論), and acupunture treatment on Atopic Disease was investigated. Methods : We have classified the patients according to the Shanghanlun six meridian patterns diagnostic system and the patients are treated with Huini-san. The severity of Atopic dermatitis was evaluated by SCORAD index, visual analogue scale(VAS) and pictures. Results : After the treatment the SCORAD index and VAS of 2 patients dicreased significantly. Conclusions : Huini-san and acupunture treatment has improved the symptoms of Atopic dermatitis in this study.

• Korean Journal of Community Nutrition
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• v.9 no.1
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• pp.90-97
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• 2004

The purpose of this study was to determined the rate of sensitization to food allergen in children with Atopic Dermatitis (AD) in Korea. A total of 3,783 patients (male = 1983, female = 1800) with AD (age under 18 years) who had visited Samsung Medical Center from 1998 to 2003 were enrolled in the study. Food hypersensitivity was measured by specific IgE to egg, cow's milk, soy, peanut, wheat, buckwheat, beef, pork, chicken, shrimp, crab, salmon, mackerel, etc. Specific IgE levels > 0.7 kU/L. by Captured Allergen Product (CAP) assay were considered positive. Chi-square test at p value < 0.05 was used to examine the difference of the prevalence by sex and age. The rate of sensitization to multiple food allergens was 31.2% and decreased with age. Hypersensitivity to egg showed highest prevalence, which was 24.3%, compared to the prevalence of other foods. High prevalence of hypersensitivity to milk. wheat, soy, peanut, crab or shrimp was observed (11.6- 17.7%). Low prevalence of hypersensitivity to beef, pork, tuna or chicken was observed (1.9-3.5%). Children aged under 3 years had significantly higher prevalence of hypersensitivity to egg, milk, soy and beef than children aged at least 3 years. Our results stress the need for examination of food hypersensitivity aimed at identified and limited each food allergen among children with AD caused by food to help patients outgrow their food allergy.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.2
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• pp.163-175
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• 2009

Objective : The aim of this study was to take a census of elementary school children who have atopic dermatitis(AD) especially the residents of Je-Cheon. Method : We conducted a questionnaire survey of the elementary school children in Je-Cheon who have atopic dermatitis. 96 patients with AD were involved in the survey. The questionnaire was made up of their family history, past history, weaning food, breast-fed or not, dietary treatment and Children's Dermatology Life Quality Index(CDLQI), etc. The student's T-test was used for statistical analysis. Results : Parents and siblings brothers and sisters past history has an effect on patients with AD. With regard to past history of patients, allergic rhinitis was the most common ailment. Formula feeding was common in the group under 6 months of age and the mean age of the start of weaning was 7.25 months. Fruit juice and weaning food of powder type were the first weaning foods in this study. Many parents introduced a grain diet, live diet, bone - soup, egg, milk, cheese and bean curd to their children under 12 months of age. A restricted diet was the most common dietary treatment method in this study. The highest scoring question for CDLQI was itching; the lowest one was related to bullying. Conclusion : We analyzed the patients' family history, past history, weaning food, dietary treatment and Children's Dermatology Life Quality Index(CDLQI), etc. Through this survey, we better understand the actual conditions of elementary school children who had AD in Je-Cheon.

• International Journal of Contents
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• v.4 no.2
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• pp.1-6
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• 2008

Pre schools with state of the art facilities that would provide not just academic excellence but also ensure the safety and provide efficient healthcare to their pupils relative to Atopic Dermatitis with Asthma is the main objective of this research One of the most promising applications of sensor networks is for human healthcare monitoring. Due to recent technological advances in sensor, low power microelectronics and miniaturization, and wireless networking enable the design and proliferation of this wireless sensor networks capable of autonomously monitoring and controlling environments. Thus, this research presents the utilization of such microelectronic sensor and plots the hardware and software architecture of a wireless sensor network system with real-time pupil monitoring that integrates vital sign sensors, location sensor and allergen sensor. This proposed architecture for wearable sensors can be used as active tags which can track pupil's location within the school's premises, identify possible atopic dermatitis with asthma allergens, it would monitor and generate a health status report of the pupil.

• Journal of Nutrition and Health
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• v.52 no.1
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• pp.47-57
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• 2019

Purpose: This study was conducted to investigate the relationship between atopic dermatitis and dietary fat and fatty acid (FA) intakes in 9 ~ 11 year old children. Methods: We analyzed data from the combined 2013 ~ 2015 KNHANES (Korean National Health and Nutrition Examination Survey). Subjects were divided into two groups according to atopic dermatitis (AD); with AD and without AD. Data pertaining to macronutrients and FA intakes were obtained by a single 24-h dietary recall. Food sources were identified based on the amounts of total fat and FA consumption according to each food. The associations between each FA intake and atopic dermatitis were analyzed using simple and multiple logistic regression analyses. Age, sex, body mass index (BMI) and income levels were adjusted as covariates. Results: Of the participants, 17.69% suffered from atopic dermatitis. Children with AD had significantly lower fat percentages of total energy and higher carbohydrate percentages of total energy than normal children. Percentages of energy and intakes of polyunsaturated fatty acid (PUFA), n-3 FA and n-6 FA in children with AD were significantly lower than those in normal children. In the FA, linoleic acid, ${\gamma}$-linoleic acid and ${\alpha}$-linolenic acid levels of children with AD were significantly lower than those of normal children. However, the P/S ratio and n-6/n-3 ratio did not differ significantly between children with AD and normal children. Soybean oil was the main contributor to PUFA, n-3 FA and n-6 FA in both groups, while perilla seed oil and mackerel were the major food sources of n-3 FA in children with atopic dermatitis. Atopic dermatitis was significantly correlated with low-fat and high-carbohydrate diets. The adjusted odds ratios were 0.966, 0.776 and 0.963 for PUFA, n-3 FA, and n-6 FA intakes, respectively. Conclusion: The present study provides reliable evidence regarding the relationship between fat and FA intakes and AD in Korean children 9 ~ 11 years of age.

• Korean Journal of Community Nutrition
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• v.18 no.5
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• pp.515-524
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• 2013

Atopic dermatitis (AD) is believed to be associated with the intake of antioxidant nutrients and fatty acids due to its immunological dysfunction. The purpose of this study was to examine the effects of nutrition education promoting vegetable, fruit, and fish intake on the severity of AD in children. Children with AD aged 6 months to 5 years were randomly assigned into education and control groups, and followed for 1 year. Seventy-six children completed the study (38 for control, 38 for education). The education group received education promoting the intakes of antioxidant-rich foods (vegetables, fruits) and n-3 fatty acid foods (fish). A 24-hour food recall was collected for the diet information. After education, all vegetables (p < 0.001), fruits (p < 0.01), and fish (p < 0.05) intakes per 1000 kcal increased significantly in the education group, whereas only vegetable intake increased in the control group (p < 0.001). The SCORAD index, the severity of atopic dermatitis, decreased significantly in the education group (p < 0.05). Increased consumption of dietary vitamin E was significantly associated with reduction in the SCORAD index, after adjusting for age and gender (p < 0.05). A nutritional education program to increase vegetable, fruit, and fish intake may be effective in reducing the severity of AD, and vitamin E intake may be associated with the decreased severity of AD. More controlled studies on the relationship between these intakes and severity of AD, with intensive diet and/or supplement intervention programs, are needed to obtain conclusive results.