• 제목/요약/키워드: children's life pattern

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21세기 초 한국의 인구구조 및 질병양상 (Perspective on Population Characteristics and Health Problems of Koreans in 21st Century)

  • 김정순
    • Journal of Preventive Medicine and Public Health
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    • 제27권2호
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    • pp.175-185
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    • 1994
  • In order to anticipate disease pattern and health problems of Koreans in the 1st part of 21st century (by the year 2020), transition of population characteristics, mortality and morbidity data during the last 30 years Koreans have experienced were reviewed. On the actual basis of epidemiologic transition process that has undergone during last 30 years since 1960 along with socioeconomic development and successful implementation of selective national health policies (family planning, medical insurance and etc.), following changes can be expected in the 21st century in Korea, under the assumption that the current rate of progress is maintained. The population of South Korea alone will be doubled the population of 1960 by the year 2013 : aged Population older than 65 years will be increased from 3.3% in 1960 to 11.4% in 2020 with increased average age of the population from 23.6 year in 1970 to 39.2 year in 2020; urban population from 28% in 1960 to 83% in 2005. GNP/capita has increased tremendously from U.S. $120 in 1970 to $6,749 in 1992, and the government estimated it would be 519,350 in 2010 and $29,460 in 2020. Growth and developmental indices of children, educational achievement and social status of women also showed a remarkable improvement and anticipated to make futher progress. Leading causes of mortality and morbidity have shown a striking change during the last 30 years, from infectious diseases to chronic degenerative diseases and man-made injuries. Occurrence of communicable diseases may become minimal although viral hepatitis, venereal diseases Including AIDS, and well adapted herpes virus infections will maintain their endemic level. Newly evolving infectious agents, however, should be carefully monitored because of rapidly changing environments and human behaviours. Tuberculosis may increase up to the epidemic level when AIDS prevails. Ischemic heart diseases may increase steadily with increasing occurrence of hypertension and diabetes mellitus whereas cerebrovascular diseases may be decreased slowly. Musculaskeletal diseases which contribute a lot to the disability of aged people may be a major health problems due to increased aged population. Mental diseases, particularly that caused by alcohol and drug abuse, and senile dementia may become a prominent health problem. On the other hand injuries caused by traffic and industrial accidents that have shown most striking increase till now may be decreased considerably by intensive intervention. The health policies in the 21st century will be oriented to the health promotion for good quality life rather than life-savings.

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니키 드 생 팔의 트라우마를 통해 살펴본 아상블라주와 사격회화의 양면적 특성 (A Study on the Ambivalent Characteristic Displayed in Niki de Saint Phalle's Assemblages and Shooting Paintings by Looking Into Her Trauma)

  • 유가은
    • 미술이론과 현장
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    • 제6호
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    • pp.77-99
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    • 2008
  • The purpose of this study is to show that the reason behind the ambivalent characteristic displayed in Niki de Saint Phalle's works is in her trauma and how such characteristic can be extracted from her works. During her creative years, Saint Phalle worked on various materials from different genres such as assemblages, shooting paintings, a series on Bride and Monster, 'Nana', 'Tarot Garden'and public sculptures. One commonality found among her various works is the ambivalent characteristic that contains contrasting elements simultaneously. Saint Phalle suffered a terrible psychological damage inflicted by her parents during her childhood. Specifically, she was sexually assaulted by her father and emotionally neglected by her mother, the trauma that affected her for the rest of her life. As a result, she came to develop extreme love- hate relationships with her parents and this became the main reason for the ambivalent characteristic displayed in her works. The love-hate relationship Saint Phalle developed can be identified through various researches done on the subject of the affect of sexual assault. It is common for incest victims to develop ambivalent feelings towards the perpetrator and Saint Phalle was no exception. Dissociation disorder and a snake well explain the trauma from her father. It is a generally accepted belief in the field of psychology that dissociation disorder commonly occurs to children who experience incest. And dissociation disorder is similar to the characteristic of ambivalence in the sense that a single entity contains more than two contrasting elements at the same time. In addition, the amputated doll objects used in her assemblages coincide with the expression of body detachment of people with dissociation disorder. These facts clearly indicate that the trauma from her father is showing through in her works. A snake is a subject matter that reflects the ambivalent tendency of Saint Phalle that resulted from her trauma. She remembers her father's rape as an image of a snake which is related to a phallic symbol in mythology or art reflecting her trauma. Moreover, she displays a similar pattern of ambivalent emotion like love and hate or fear towards a snake and her father. This is also confirmed by her portrayal of a snake as a monster or reversely as a creature with fundamental vitality in her works. The lack of affection from her mother can be explained by her mother's maternal deprivation. It appears that Saint Phalle's mother possessed all the causes for maternal deprivation such as maternal separation, personality disorder and inappropriate attitude towards child rearing. Especially, a study that shows mother's negative attitude towards child breeding tends to increase dissociation experience of children is another important evidence that supports Saint Phalle's dissociation tendency. These traces of Saint Phalle's trauma are clearly revealed in her assemblages and shooting paintings. The violent objects in her assemblages such as a hammer, razor, nail represent the rage and defensiveness towards her father. The objects such as fragments of broken plates of feminine patterns, pots and mirrors that her mother used symbolize the affection towards her mother. On the other hand, the destructed objects can be interpreted as her hate and resentment towards her mother. Shooting paintings contain her extreme fury and hate. Things such as acts of shooting and the image associated with blood after shooting are blunt expressions of her bursts of emotions. I have tried to define and classify the ambivalent characteristics shown in her assemblages and shooting paintings as hate, rage, violence, calm, love and pleasure according to the frame of Thanatos and Eros. Out of the six, hate, rage, violence and clam are associated with Thanatos while love and pleasure are associated with Eros and they correspondingly form an ambivalent structure. These ambivalent characteristics can be found in her assemblages and shooting paintings. The objects in her assemblages such as a razor, saw, hammer imply hate, rage, violence and the silence felt throughout her works represent calmness. And, as mentioned, the feminine objects can be seen as symbolizing love. In shooting paintings, hate, rage, violence can be found in the use of force and in the traces of watercolor after shooting, and a sense of pleasure in her feelings of catharsis after her shooting. Moreover, a shielded calmness can be found on the plywood all covered with plaster before the shooting. This study looked into the ambivalent characteristic of Saint Phalle's works by examining her trauma to find its correlation, and a meaning of this study can be found from the fact that it refocused the origin of Saint Phalle who is generally known as a feminist artist. Additionally, a meaning of the study can be found also from the fact that it examined the ambivalent characteristics of her works through a frame of Thanatos and Eros.

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가정학교육 영역에서의 인구교육문제에 관한 조사연구 -선임가정학자들을 대상으로- (A Study of the Attitude of/and Problems Encountered by Senjor Home Economist Toward the Integration of Family Planning Education in the Korean Formal School System)

  • 김지화
    • 대한가정학회지
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    • 제19권3호
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    • pp.83-101
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    • 1981
  • Under the full consideration of the growing need and importance of population education in the field of home economics in Korea, the study was carried out to verify and assess the following facts on the current issues of population education of home economists who are presently engaging in teaching professions as the teachers of middle and high school and professors of college and universities by setting its primary objectives of the study as followings; 1) to assess the degree of general knowledge and attitudes of home economists toward population education in the field of home economics, 2) to verify the problems encountered in implementing population education by home economists in its field, 3) to find an existing status of previous trainings received and other activities of population education of home economists aimed at utilizing these findings as a part of reference materials when the population education is conducted in the field of home economics. In order to attain these objectives described above, the questionnaire was carefully designed to house a total of 40 questions with good combination of multiple-choice and the simple answer questions. The mail questionnaire survey was conducted by establishing teachers of home economics at middle/high schools and college/universities as Senior Home Economists(SHE) who are from public, private liberal arts and vocational schools. The rate of response observed during the survey was 45.6 percent and the findings of the survey research are as follows: 1) Examining the status of the respondents by residence and religion, it was found that 45 percent of middle & high school teachers ar.d 59. 1 percent of college professors are residing in Seoul city area and that the largest percent of them are christian in their religion. Analyzing respondents by their ages, 56 percent of middle/high school teachers are in their 30s, 45 percent of college professors are in their 40s, and 37 percent of college teachers are in their 30s. In addition, 13 percent of the total respondents are found to be unmarried. The study also revealed that 71 percent of the college professors finished Master Degree course and 82 percent of middle/high school teachers are graduated from college level lasting 4 years. Looking over the status cf major fields of respondents, 68.4 percent of middle/high school teachers are specialized in home economic education and the college professors, on the other hand, show relatively even prortion by specializing in the order of food & nutrition science, clothes & textile science and home managerial science. As far as the length of teaching experience is concerned, a relatively longer period of teaching experience is observed in the college professors in comparison with that of middle/high school teachers. In other words, 33.3 percent of middle/high school teachers are experienced in teaching from 6 to 10 years on average while 43.9 percent of college professors show more than 16 years of experience. 2) Examining the status of existing number of children cf the respondents, one boy and one daughter pattern is predominant, showing 28.5 percent in middle/high school teachers and 21.1 percent in college professors. As for the desired number of children of unmarried respondents, it is observed that 43.8 percent of middle/high school teachers desire to have one boy and one girl, and 31.3 percent of college professors want to have one child regardless of the sex. By assessing the degree of awareness of the population education through their students, it is observed that 53 percent of middle/high school teachers and 50 percent of college professors are aware of population education in some extent and that a majority of respondents took the positive attitudes toward an inclusion of family planning components into the formal school education. Another noteworthy to observe is that a total of 84.8 percent out of middle/high school teachers pointed that the population education currently conducted at schools as a part of home economics are less sufficient than it should be. 3) Analyzing the tendency as to whether the respondents were experienced in receiving population education during the time when they were students, 75 percent of college professors and 59 percent of middle/high school teachers responded negative answers in the survey. In the mean time, a total of 50 percent of the respondents replied that they began to acknowledge the importance of population education mainly through the participation of some sort of population-education orientend seminars, experienced by 40 percent of college professors and 80 percent of middle/high school teachers. 4) What it calls attention in this study was to find that 96.5 percent of middle/high school teachers and 72 percent of college professors conduct population education to some extent during their lecture hours and that more than 80 percent of them are never experienced in teaching population and family planning contents in their regular classes. It is, on the other hand, found that no more than once was the response of those who believe themselves that they are experienced in teaching these relevant components to their students. Analyzing the contents of the subjects being taught in the class, a large percent of them are found to be consisted of population and family planning contents. According to this study, the current population education through the formal school is quite inactive. Analyzing the facts, 44.9 percent of the college professors responded that the population and family planning components are quite apart from their specialization which eventually generates lack of interest in the field. 5) It is also noticed through the study that the degree of frequency of commenting on population and family planning contents during the classes was depending significantly on their specializations which means that the degree of frequency varies from a major to another. Those who majored in home managerial science was the first one, as compared to others who majored in different specializations. Glancing over the status of correlations between ages of the respondents and numbers of seminar paticipation, it is quite clear that the aged group participated more than the younger group did, and that the most highest number of participations made by college professors were those who are in 50s. In addition, it is also found that those who are aged 20s and 60s of the respondents were the group who comments least on the contents of population and family planning at their classes. The suggestions and recommendation made through this survey research are as follows. 1) No one denies that the rapid increase of population, as compared to the limited size of land and resources, will certainly affect adversly to an enhancement of individual life quality which will, eventually, bring forth the poverty of the nation. This is the reasson why we are insisting that the world population be controlled up to an optimum level with a matter of global concerns. It is our understading that the primary aim for reducing number of population is believed to be attained only by conducting the systematic and comprehensive population education through the formal schools. Therefore, the role of home economists in the field of population/family planning education is considered very importment due to the fact that an ultimate goal of population education is placed in elevating the quality of family life by having optimum number of children through family planning program. 2) It is quite clear that home economists as teachers of formal school in all level are invited to pay their attention on redefining the ultimate goal of education and that of population education. We also understant that the primary objective of population education is to change the norm and value of the clients by replenishing the students with pertinent knowledge and attitudes on population and its related problems through a sort of education in order to attain the ultimate goal for enhancing the quality of life. There is no exception in the theory of home economics. An altimate goal of home economics is to elevate the general quality of life through an establishment of value existed in daily life. Considering the relations between population education and home economics, it is quite indespensable to bandle population components as an integral part in the field of home economics. We believe, therefore, that the senior home economists positive participation in the effort population control is more needed than it has been. 3) It is also strongly urged that population education should be a part of instructor training course for home economics. In other words, the teacher of home economics should be well aware of population and its problems by teaching interrelationship between population education and home economics, needs, contents and methods of population education during the instructor training courese for home economics. In addition, the senior home economists should be encouraged through positive participation on the short term training by types of domestic and international seminar, workshop, etc. 4) We certainly believe that the population education can not sustain itself without any backing-up of information and findings' of various and comprehensive researches of natural and social sciences. Accordingly, every senior home economist is invited to exert their maximum effort to conduct systematic study with an aim to utilize these findings and information at best in population education in the field of home economics. Therefore, we consider that the development of training material is imminent in order to provide effective and efficient population education through the for training of home economies. It should be noted that these training materials must be carefully designed, tailored and developed to meet the different classes of trainees under the considerations as to whether it is easily adaptable and infusable into the curricula of every field of home economics, and it is acceptable in the degree of difficulty and quality in its contents. 5) It is true that there are many domestic and international research rapers, reports and findings in the field of population education and family planning. However, there is a tendency that the most of research papers are heavily relying on the authors intension and preferences in its expression and publication. Under these circumstances, it is urged that the home economists should aware of the growing need of the technical training in order to keep these available information and research findings reprocessed and redesigned to insure the practical application into the population education in the field of home economics in Korea.

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다문화가정 결혼이주여성의 출신 국가에 따른 식생활행동 조사 (Dietary Behavior of Marriage Migrant Women according to Their Nationality in Multicultural Families)

  • 김정현;이명희
    • 대한지역사회영양학회지
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    • 제21권1호
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    • pp.53-64
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    • 2016
  • Objectives: Nowadays, the multicultural families make up significant portion of Korean population and communities. Successful re-settling in a new country can be difficult, particularly when there are disparities in dietary behavior compared to home country. The objective of the study was to investigate the dietary behavior of marriage migrant women according to their nationality in multicultural families. Methods: The primary research was conducted targeting 94 marriage migrant women who came from China (40.4%), Vietnam (26.6%), and other countries except for Japan (33.0%). We investigated their dietary behavior, such as eating attitude and food choice behavior for Korea acculturation. We also studied dietary behavior among 14 selected subjects who had high level of integration and assimilation acculturation patterns by administering the Focus Group Interview (FGI). Results: The multicultural families had more integration acculturation patterns, which could have been influenced by their nationality. Vietnamese origin has the highest cultural adaptation as marginalization pattern. The common types of Korea acculturation were integration ($3.03{\pm}1.08$), separation ($3.10{\pm}0.59$), marginalization ($3.10{\pm}0.58$), followed by assimilation ($2.84{\pm}0.51$). There were significant differences in the four types of acculturation by marriage immigrant women's country of origin (p<0.05). According to dietary behavior, 'eliminating hunger' was the most important value in a meal. Chinese marriage migrant women, who had higher level of food intake attitude significantly, also considered 'being healthy' an important value. Regarding food choice behavior, Vietnamese had lowest frequency of homeland food intake. Most of marriage immigrant women were satisfied with the Korean food, and need for education was very high with interest for cooking, good nutrition, and managing their children's dietary life. Conclusions: Coping with a change in dietary behavior is one of the biggest transitional difficulties, and family members may need support to find their familiar food items and to continue their cultural food choice behavior in the local areas. Further researches with quantitative and qualitative analysis are needed to understand the effect of dietary behavior for acculturation in multicultural families.

시술장소에 따른 65세 이상 노인의 의치보철 실태 조사연구 (A Study on the Actual Conditions of Denture Prosthodontics used by the Elderly Aged 65 or Older in Seoul)

  • 정정옥
    • 치위생과학회지
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    • 제7권3호
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    • pp.113-119
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    • 2007
  • 본 연구는 노인의 의치보철 실태를 파악하여 의치보철 시술 장소에 영향을 미치는 요인을 파악하기 위해 2006년 3월 2일부터 4월 15일까지 서울시에 거주하는 65세 이상 노인 219명을 대상으로 설문조사를 실시하였으며, SPSS 12.0의 프로그램을 이용하여 통계 분석한 결과는 다음과 같다. 1. 의치보철 시술 장소에 따른 의치보철 상태 및 구강 내 증상으로 의치보철 치료비, 의치보철 사용기간, 정기적 검진, 하루사용정도, 통증정도, 새로운 의치보철 필요 여부와 이유, 의치보철 급여여부로 분류되어 조사되었다. 의치보철 급여여부를 제외한 나머지 문항에서 무면허 업소와 치과병 의원사이에서 통계적으로 유의한 차이를 나타냈다(p < 0.05). 2. 의치보철 시술 장소에 따른 만족도의 차이에서는 심미성 만족의 경우에는 치과병 의원보다 무면허업소가 높게 나타났으며 발음기능, 저작기능, 통증, 이물감, 유지력에 대한 만족도의 차이에서는 무면허 업소에 비해 치과병 의원이 높게 나타났다(p < 0.05). 3. 무면허 진료와 치과진료에 대한 지각요인에 대한 요인분석 결과 4개의 요인으로 분류되어 신뢰성, 현대성, 편의성, 구전의도로 나타났다. 무면허 업소는 신뢰성에 대한 요인 선택에 가장 높은 수준이었고 편의성, 구전의도, 현대성 순이었다. 치과병 의원에 경우도 신뢰성에 대한 요인이 가장 높았지만 다음으로 편의성, 현대성, 구전의도 순으로 나타났다. 또한 지각상태에 대한 무면허 업소와 치과병 의원의 차이를 보면 신뢰성요인은 무면허 업소가 더 높은 수준을 나타냈고 현대성과 편의성 요인에서는 치과병 의원이 높게 나타났으며 유의한 차이를 보였다. 구전의도 요인에서는 치과병 의원이 높은 수준을 나타냈다(p < 0.05). 4. 의치보철 시술 장소에 영향을 미치는 요인을 분석하기 위해 의치보철 시술 장소를 종속변수로 성별, 연령, 학력, 주거형태, 지역구, 거주지 평수, 생활비, 용돈의료비, 본인명의 재산, 의치보철 지불비용은 독립변수로 하여 로지스틱 회귀분석을 실시하였다. 주거형태에서는 자녀와 동거일경우 강남에 거주할수록, 거주지 평수가 넓을수록, 용돈의료비와 본인 명의 재산이 많을수록 무면허업소에 비해 치과병 의원을 이용할 가능성이 높게 나타났다(p < 0.05).

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태교 실천에 대한 일상생활 기술적 연구 (An Ethnographic Study about Taegyo Practice in Korea)

  • 김현옥
    • 대한간호학회지
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    • 제27권2호
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    • pp.411-422
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    • 1997
  • The purpose of this study is twofold : (i) to investigate how much effort the married couples are making for the good health of both the pregnant woman and her unborn child from the time of their marriage to and during the period of conception : and (ii) to comprehensive investigate socio-cultural back-grounds which affect prenatal effort. Result of this study provide a basis for the prenatal care program which will be appropriate to our culture. This study has been done by the ethnographic research method. The subjects of this study are 53 people in all consisting of 33 pregnant women and 20 husbands. In order to investigate socio-cultural factors which influence Taegyo, producers of Taegyo music were interviewed. In addition the researcher surveyed the markets of Taegyo music, participated in special courses of prenatal education, analyzed the content of the books and periodicals dealing with Taegyo, and collected the concept of Taegyo distributed by the mass media. The full-fledged study continued for eight months from February to August.1996. The data were analyzed as soon as they were collected. Spradly's(1979, 1980) developmental, sequential method of domain analysis. taxonomic analysis, componential analysis, and theme analysis in this order was adopted as the procedure of analyzing the data. To obtain the exactness of study, Sandelowski's (1986) four criteria, that is, Credibility, Fittingness, Auditability, and Confirmability were applied to all stages of data collection, data analysis, the interpretation of the result, and the description of the result. The following are the result : 1. The couples' Taegyo at the stage of preconception was related to their physical, psychological, spiritual conditions under which a healthy baby will be born. Specific methods they prefer are : "the choice of one's spouse." "physical check-up," "physical good health, " "praying, " and so on. 2. When the marriod couple have sex in order to conceive, their Taegyo was related to the imposition of their physical, psychological, and environmental conditions. Specific methods they prefer are : "having sex at specific time, " "having sex in nice place." "to purify their minds while having sex," and so on. 3. The married couples' Taegyo while they are in pregnancy was related to the imposition of their physical. psychological, emotionmental. environmental, social and spiritual conditions. Specific methods they prefer are : "listening to music. " "reading," "looking at beautiful things only," "to avoid looking at or listening to bad things." "to eat food in good shape, " "to avoid drugs," "eating Korean herbal medicine." "sexual abstinence," "to avoid dangerous places," "to keep emotional tranquility," "moderate exercises and rest." "leading a pure life." "praying." "being aware of their words and behavior." "for the couple to keep a good relationship." "interaction with their unborn child," "to support Taegyo for pregnant women," and so on. 4. The married couple put Taegyo into practice on the basis of the following principles : the principle of respecting an unborn child, the principle of forming a good disposition. the principle of top-down parental love, the principle of synergy between a pregnant woman and her unborn child, the principle of expecting a good child, the principle of forming a good habit, and the principle of acquiring a parental role. 5. The practice of Taegyo is influenced by such factors as the married couple, the supporting system, and the mass media. As the husband -and-wife factor, their information of Taegyo, the degree of importance is assigned to their characters, their time to spare, their healthiness, the age of pregnant woman, their conception plan, their religion, their belief of the Taegyo effects, and the birth of a baby in this order. The factor of the supporting system consists of her husband's support, her family support, and her neighbor's support. The mass media factors include the broadcasting media, books specialized in Taegyo, periodicals for pregnant women, booklets for advertizing powdered milk, Taegyo music of record manufacturing companies, and the teaching materials for gifted children. Among these the mass media is especially taking advantage of Taegyo as its main source of economic profits are leading the public behavior pattern to a prodigal one. Taegyo is a self-control behavior which requires practice for the following : the physical and psychological good health of the pregnant woman and her unborn child, the development of the unborn child's good character, the development of the unborn child's intelligence and talents, the expectation of the unborn child's good features. shape a good habit, the expectation of the unborn child's bright future, and the learning of a parental role, the expectation of male birth. Above all it is a type of our good cultural tradition which pursues a value higher than the one that the prenatal care does. The principles of pregnancy care inherent in the habit of Taegyo will provide us a guideline for the development of the prenatal care.

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10세에서 14세 사이 III급 부정교합자의 치아안면두개의 형태학적 특성에 대하여 (Dental and skeletal characteristics and growth in Class III malocclusion between skeletal ages of 10 and 14)

  • 민승기;이영준;박영국
    • 대한치과교정학회지
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    • 제33권6호
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    • pp.419-435
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    • 2003
  • 이 연구는 두부X선 규격사진을 이용하여 III급 부정교합자의 안모를 연령 성별로 분류하고,각 분류에 대한 두개 안면 형태의 특성을 구명하기 위하여 시행되었다. 정상교합자 60명과 III급 부정교합자 60명을 표본으로 하였으며 각 군은 10세, 12세, 14세 군 남녀로 구분되었다. 50개의 선 및 각계측치를 Krogman-Walker의 기준평면을 기준하여 측정하였다. 1. III급 부정교합군은 전방두개저의 길이와 안상각이 정상교합자군에 비하여 작고 하악골체와 하악수직고경이 큰 것으로 나타났으며, 이러한 차이는 남녀 모두 10세부터 유의하게 나타났다. III급 부정교합군에서의 하악하연각의 유의한 증가는 남녀 모두 12세때 나타났다. 2. III급 부정교합자군에서의 상악골의 후방 위치와 상악골체 크기의 유의한 감소는 남녀 모두 10세부터 나타난다. 3. III급 부정교합자군에서 유의한 하안면부 수직고경의 증가는 주로 하악골체 크기의 변화에 기인하는 것으로 관찰되었다. 하악골체의 경우 III급 부정교합자군에서 더 크고 전하방에 위치하는 것이 관찰되었다. III급 부정교합자군에서의 전체적인 수직고경의 유의한 증가는 12세군에서 유의하게 나타나기 시작한다. 4. 본 연구에서는 III급 부정교합자군에서의 두개저부각의 감소와 (Ba-S-N, 3A) 하악골체의 전방 위치는 남녀 모든 연령층에서 일관되게 관찰되었다. 이 결과는 Rothstein 등에 의해 주장된 II급 부정교합자군에서의 두개저부각의 변화가 하악골체의 전후방 위치에 영향을 주지 못한다는 주장을 부정하며, 디벳 등에 의해 주장된 앵글씨의 부정교합분류와 두개안면형태의 상관성에 대한 연구를 지지한다.

Paraquat에 의해 유도된 Superoxide Dismutase 결핍 효모의 산소 독성 (Oxygen Toxicity of Superoxide Dismutase-Deficient Saccharomyces cerevisiae by Paraquat)

  • 김지면;남두현용철순허근
    • KSBB Journal
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    • 제10권5호
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    • pp.561-567
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    • 1995
  • 활성산소 소거 효소인 superoxide dismutase (SOD)가 결핍된 효소 변이주들을 대상으로 하여, 활성산소 유발물질인 paraquat을 배지에 첨가하여 배양하면서 산소 독성을 관찰하였다. 호기 상태에서 는 MnSOD (mitochondria SOD) 결핍 효모는 CuZnSOD (세포질 SOD) 결핍 효모보다 성장이 많 이 저하되었지만, 혐기 상태에서는 이들 SOD 결핍 효모 모두 성장 속도에서 야생 효모와 큰 차이를 보이지 않았다. Paraquat으로 처 리한 결과, 호기 배양 에서 CuZnSOD 결핍 효모는 O.OlmM 이상에서 성 장하지 않음을 알 수 있었다. 따라서 O.OOlmM paraquat을 배지에 첨가한 후 호기적으로 배양하면서 세포내 성분의 변화를 관찰하였더니, CuZnSOD 결핍 효모에셔는 catalase 역가가 떨어진 반면 glutathion peroxidase 역가와 세포막 지질의 과산 화물이 증가하였으며, MnSOD 결핍 효모에서는 catalase 역가와 glutathion peroxide 역가가 모두 조금씩 증가하면서 세포막 지질의 과산화물은 그다지 변화하지 않았다. 이러한 사실로부터 CuZnSOD 가 없는 경우 활성산소 소거계로써 catalase 보다 glutathion peroxidase가 훨씬 활성화되어지지만, 이렇게 활성화된 glutathion peroxidase로는 세포질내 산소 radical을 완벽히 제거하는데에는 다소 불충분 하다는 사실을 알 수 았었다. 한편, 혐기적 배양에서 는 SOD 결핍 효모들의 catalase 역가는 모두 감소 한 반면, glutathion peroxidase 역가는 다소 증가하였고, 또한 세포막 지질의 과산화물은 다소 감소하는 추세를 보였다. 이는 혐기 상태에서 산소 radical 이 소량밖에 생기지 않으므로, 활성화된 glutathion p peroxidase에 의해 어느 정도 극복되어지기 때문인 것으로 사료된다. 두 집단 간에 어느 정도 방향성은 있는 것으로 판단된다.ds for eagerness for lasting life not only in this world but also in the other world., Keun-Kap, Scarf, Pee-Bak, Hung-Kap, Pok-Kap, Yang-Dang-Kap, We-Yo-Kap, Kum-Kap, and caries arms. Lower-level officials wore Pe-Bal, Kun-Mo, gae, won-leung, very small sleve jacket, a long coat reaching up to the knee length, slacks, belt, loin cloth and apron. 5) Children's bind their hair up angle shape and wore a half long jacket raching up to the hip and slacks. 나) Women's wear; 1. hair style and hair dress; 1) High rank women's hair style was very extravaganceful. They made their hair top knot (one, two, or more knots) and decoraed precious stone, pan shape head dress, wheel shape head dress, and flower shape precious stone decorated head dress. 2. Clothes ; 1) High rank ladi's wore Kun-Kyun attached jacket, and jacket sleeves decorated pleats, and pleats decorated long skirt, apron, back apron, knot belt, scarf, this type is the same

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청소년의 컴퓨터게임 이용실태, 부모양육방식, 개인의 정신병리 (COMPUTER GAME PLAYING PATTERNS, PARENTAL REARING PATTERNS AND INDIVIDUAL PSYCHOPATHOLOGY IN ADOLESCENTS)

  • 류정환;김영미;정홍경;조아라;이정호;최영민;이기철;전성일
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제11권1호
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    • pp.27-41
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    • 2000
  • 연구목적:오늘날 컴퓨터게임은 청소년기의 보편적 놀이도구가 된 상황임에도 불구하고 이들이 게임에 몰두하는 이유와 개인특성에 관한 정신과적 연구는 드문 실정이다. 이러한 필요성에서 본 연구는 중학교 2년생을 대상으로 청소년의 컴퓨터게임 사용실태를 파악하고, 연관된 개인정신병리와 부모의 양육방식과의 관계를 밝히고자 하였다. 방 법:이 연구는 서울시 노원구에 위치한 중학 2년생 124명을 대상으로 하였다. 정신병리의 측정을 위하여 한국판 간이정신진단검사(SCL-90-R)을 사용하였고, 부모자녀 결합형태 조사(PBI)를 통하여 부모양육태도를 알아보았다. 결 과:1) 비록 과도한 시간을 들여 컴퓨터게임을 하더라도, 컴퓨터게임과 연관된 특정 정신병리는 발견할 수 없었으며 따라서 컴퓨터게임은 청소년기에 있을 수 있는 일상적인 놀이문화이다. 또한 대부분의 청소년은 컴퓨터게임이 문제가 되지 않는다고 인식하고 있었다. 2) 남학생은 게임빈도, 게임시간, 게임방에서 보내는 시간, 게임을 한 번 할 때 지속하는 시간 등에서 여학생에 비해 통계적으로 의미 있게 높은 수치를 보였다. 3) 청소년의 신체증상호소, 타인간의 관계에서 나타나는 불편감, 우울증, 불안증의 정신병리는 컴퓨터오락으로 인한 부작용과 의미 있는 관계를 보였다. 4) 게임빈도와 PBI상의 어머니 과보호척도는 정적인 상관관계를 보였다. 5) 게임을 하는 이유로는 공부, 학교 생활 등의 복잡한 것을 잊고 몰두하기 위해가 가장 많았고, 가장 심리적으로 부담이 되어 피하고 싶은 것으로는 학업문제였다. 6) 청소년은 게임방을 주로 친구들과 어울리는 공간으로 사용하고 있었지만 그 기능을 다하기에는 아직 보완해야 할 점이 많다. 결 론:게임으로 인한 부모, 교사와의 다툼, 잦은 지각/결석, 친구들과 어울리지 못하는 등의 문제가 많은 경우에는 청소년 자체의 정신병리를 의심해 보아야 하며, 게임의 빈도가 의미 있게 높은 청소년의 경우에는 동반되는 정서상의 문제와 함께 부모양육태도도 함께 세심하게 살피는 것이 필요하다.

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페닐케톤뇨증의 임상적 고찰 (Clinical Findings of Phenylketonuria Patients in Korea)

  • 신익순;이동환
    • 대한유전성대사질환학회지
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    • 제12권1호
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    • pp.14-22
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    • 2012
  • 목적: 본 연구는 본원으로 전원되어 전형적 PKU로 확진된 환아들의 임상양상에 대해 알아보고자 하였다. 방법: 1983년 1월부터 2010년 8월까지 서울 순천향대학교 서울병원 소아청소년과를 방문하여 고페닐알라닌혈증으로 진단된 환아 178명 중 전형적 PKU로 진단된 환아 161명을 대상으로 MRI 영상소견, 골연령, 치의학적 상태, 뇌파검사, 지능평가, 유전자 분석에 대한 조사를 하였다. 결과: BH4비반응형 전형적 PKU는 134명, BH4반응형 전형적 PKU는 22명, 양성고페닐알라닌혈증은 5명으로 전형적 PKU는 161명이었다. PTPS 결손증 14명, DHPR 결손증 2명, GTPCH 결손증 1명으로 BH4 결손증은 17명이었다. 111명의 전형적 PKU환아에서 시행한 유전자 분석에서 R243Q (10.3%), Y204C (9.9%), IVS4-1G>A (8.1%) 변이가 흔히 나타났으며 이외에도 총 29가지의 유전자형이 밝혀졌다. MRI 검사는 총 22명이 시행했으며 정상 5명(25%), T2 강조 영상에서 두정엽의 특히 뇌실 주변부 백질의 고 신호강도를 보인 경우가 15명(75%)로 나타났다. 11명에서 척추 골밀도 검사를 시행했으며 4례(36%)에서 1표준 편차이상 골밀도가 감소한 골다공증의 소견을 보였고, 4례(36%)에서 1년 이상 골연령이 지연되었다. 47.8%에서 비정상 뇌파소견을 보였다. 18명이 지능평가를 시행했으며 평균 지능지수(IQ)는 $84{\pm}21.6$점이였고, 이중 15세 이상의 경우 9명으로 평균 지능지수는 $72{\pm}21.2$점으로 나타났다. 결론: 본원으로 전원되어 전형적 PKU로 진단된 환아 중 15세 이상의 경우 평균보다 낮은 지능지수와 아스퍼거 증후군, 정신지체 뿐만 아니라 공격적 성향의 행동을 보이는 경우가 많았다. 이는 영유아기에 비해 사춘기 때 저페닐알라닌 식이를 잘 지키지 않는 경우가 많기 때문으로 생각되며 향후 지속적인 저페닐알라닌 식사요법의 유지교육이 중요할 것으로 사료된다.

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