• Asian Pacific Journal of Cancer Prevention
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• v.16 no.10
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• pp.4409-4419
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• 2015

The Bhopal gas tragedy involving methyl isocyanate (MIC) is one of the most horrific industrial accidents in recent decades. We investigated the genotoxic effects of MIC in long-term survivors and their offspring born after the 1984 occurrence. There are a few cytogenetic reports showing genetic damage in the MIC-exposed survivors, but there is no information about the associated cancer risk. The same is true about offspring. For the first time, we here assessed the micronucleus (MN) frequency using cytokinesis-blocked micronucleus (CBMN) assay to predict cancer risk in the MIC-affected population of Bhopal. A total of 92 healthy volunteers (46 MIC-affected and 46 controls) from Bhopal and various regions of India were studied taking gender and age into consideration. Binucleated lymphocytes with micronuclei (BNMN), total number of micronuclei in lymphocytes (MNL), and nuclear division index (NDI) frequencies and their relationship to age, gender and several lifestyle variabilities (smoking, alcohol consumption and tobacco-chewing) were investigated. Our observations showed relatively higher BNMN and MNL (P<0.05) in the MIC-affected than in the controls. Exposed females (EF) exhibited significantly higher BNMN and MNL (P<0.01) than their unexposed counterparts. Similarly, female offspring of the exposed (FOE) also suffered higher BNMN and MNL (P<0.05) than in controls. A significant reduction in NDI (P<0.05) was found only in EF. The affected group of non-smokers and non-alcoholics featured a higher frequency of BNMN and MNL than the control group of non-smokers and non-alcoholics (P<0.01). Similarly, the affected group of tobacco chewers showed significantly higher BNMN and MNL (P<0.001) than the non-chewers. Amongst the affected, smoking and alcohol consumption were not associated with statistically significant differences in BNMN, MNL and NDI. Nevertheless, tobacco-chewing had a preponderant effect with respect to MNL. A reasonable correlation between MNL and lifestyle habits (smoking, alcohol consumption and tobacco-chewing) was observed only in the controls. Our results suggest that EF and FOE are more susceptible to cancer development, as compared to EM and MOE. The genotoxic outcome detected in FOE reflects their parental exposure to MIC. Briefly, the observed cytogenetic damage to the MIC-affected could contribute to cancer risk, especially in the EF and FOE.

• Journal of The Korean Society of Grassland and Forage Science
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• v.33 no.4
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• pp.290-297
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• 2013

This study was carried out to investigate the effects of a by-product feed-based silage (BF silage) feeding on behavior patterns of growing Hanwoo steers. A total of 10 Hanwoo steers (11 months old, 302kg of body weight) were assigned to 2 dietary treatments: the control (concentrate mix + free access to rice straw), and the treatment (concentrate mix + free access to BF silage). The behavior patterns were observed for 48 hours. The intakes of dry matter (DM) and neutral detergent fiber (NDF) of the treatment group were higher than those of the control group. Eating time, ruminating time and resting time were not different between the control and treatment. But, the intake time per kg DM was higher for the control than treatment. The number of bolus, total chewing frequency, number of ruminating per bolus and number of bolus per minute were not different between the control and treatment. But the chewing frequency per bolus was higher in the treatment than control (p<0.05), and feed value index was lower in treatment than control (p<0.05). Frequencies of drinking and defecating were not different between the two groups, but the frequency of urinating was higher for the treatment (p<0.05) than control. Eating rate, ruminating efficiency and chewing efficiency were much higher in the treatment group than control (p<0.05). These results indicate that the replacement of conventional rice straws with the BF silage (physically effective NDF, about 25%) did not affect the ruminating behaviors of Hanwoo steers significantly.

• Journal of Animal Science and Technology
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• v.57 no.1
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• pp.3.1-3.6
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• 2015

This study investigated the effects of feeding by-product feed (BF)-based silage on the behavior of growing Hanwoo heifers. Twelve Hanwoo heifers (13.2 months-old, 315 kg body weight; four heifers per pen) were assigned to three diets: a rice straw (RS) diet (concentrate mix and free access to RS), a RS and BF-based silage (RSBFS) diet (concentrate mix and free access to RS and BF-based silage), and a BF-based silage (BFS) diet (concentrate mix and free access to BF-based silage). Behavior was recorded for 5 days using camcorders. Compared to the RS group, the BFS group showed 21.7% higher dry matter intake, shorter feeding, rumination, and chewing times, as well as longer resting time (p < 0.05). Although all groups exhibited similar drinking, urination, and defecation frequencies, the BFS group exhibited higher feeding rates, rumination efficiency, and chewing efficiency than the RS group (p < 0.05). Compared to the BFS group, the RSBFS group showed higher $peNDF_{8.0}$ intake (15.2% vs. 25.0% dry matter intake), longer feeding and sitting times, lower defecation frequency (p < 0.05), and similar rumination efficiency. In conclusion, complete replacement of conventional RS with BF-based silage reduced rumination and chewing activity in growing Hanwoo heifers, and BF-based silage feeding with large-particle straw is an effective approach in improving heifer behavior.

• Journal of Korean society of Dental Hygiene
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• v.16 no.2
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• pp.285-293
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• 2016

Objectives: The aim of the study was to investigate the association of self-perceived oral health and depression in the Korean elderly. Methods: The subjects were 1,329 elderly in Korea from the sixth Korea National Health and Nutrition Examination Survey (the 6th KNHANES). The dependent variable was depression that continued more than two weeks. Model I for the impacts of depression on self-reported oral health, Model II for the impacts of depression on chewing problem, Model III for the impacts of depression on speaking problem was evaluated. PASW Statistics 18.0 version was used for frequency analysis, chi-square test and logistic regression analysis. Results: Female elderly were much more prone to depression than male. Female had lower monthly compensation, less medicaid, chewing problem, speaking problem, and less education. For these reasons, they tended to have more depression than male (p<0.001). Self-perceived oral health impacts on depression included poor self-reported oral health(p<0.01), poor chewing problem(p<0.01) and poor speaking problem(p<0.05). On the other hand, male did not show a statistically significant association. Conclusions: The study showed the self-perceived oral health related quality of life had a significant influence on depression in the elderly. The continuing lifelong oral health care can prevent depression in the later life because oral health care improvement can enhance the self-perceived oral health status.

• Journal of Korean society of Dental Hygiene
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• v.15 no.6
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• pp.973-981
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• 2015

Objectives: The purpose of the study is to investigate the correlation with subjective oral health status and food preference in elderly people. Methods: Data were extracted from the fifth Korea National Health and Nutrition Survey 2010-2012. The survey data included general characteristics of the subjects, food preference, and subjective oral health status. Food preference was analyzed by assigning score to 63 food categories. The subjective oral health status consisted of toothache within a month, self-perception of oral health, chewing difficulty, mastication difficulty, and speaking difficulty. Data were analyzed by frequency analysis, descriptive statistics, ${\chi}^2$ test, t-test, and ANOVA using SPSS 22.0 program. Results: Elderly men had a tendency to have a liking for all food categories except for fruit. Difficulty in chewing and mastication was shown in those who had older age, lower education, lower monthly income, and national basic livelihood security. Difficulty in speaking was found in those who had older age, lower education, and national basic livelihood security. Self perception of oral health status was closely related to food preference for pulses and potatoes, fish, vegetables and others(p<0.05). Difficulties in chewing and mastication had relation to all food categories excepting cereals, lipids and sugars(p<0.05). Speaking difficulty were significantly different in pulses, potatoes, meat, eggs, vegetables, fruits, milk, dairy products, and others(p<0.05). Conclusions: Poor subjective oral health status was closely related to food preference. It is necessary to educate that maintenance of good oral health is to ingest the balanced nutrition in the elderly people.

• Journal of Convergence for Information Technology
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• v.11 no.4
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• pp.153-160
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• 2021

Goal of this study is to introduce newly developed Oral Motor Facilitation Technique(OMFT), to identify effect of oral motor therapy on oral praxis and oral function of Down syndrome child. OMFT is comprehensive oral motor therapy for improving sensory adaptation, oral sensori-motor function, oral motor coordination of oro-facial structure by therapist's direct manual stroking. Subject was 10years old down syndrome boy. Treatment was practiced 8 times, 15minutes per time, from May to July, 2020. Oral praxis, drooling, quality of chewing ability were tested before and after treatments. Every single items of Oral Praxis Test was increased. Severity and frequency of drooling were decreased. Quality of chewing ability is improved. Through this case study, we can find the positive effect of OMFT on oral praxis, drooling, chewing ability of Down syndrome child.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.4
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• pp.199-211
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• 2023

Purpose : Rapid population aging in South Korea is emerging as serious social problems, and interest in the health-related quality of life of the elderly is also increasing. Therefore, this study attempted to provide basic data to develop measures to improve the health-related quality of life of the elderly by identifying the impact of the elderly's dietary lifestyle on the health-related quality of life. Methods : Utilizing raw data from the Korea national health and nutrition examination survey spanning from 2011 to 2020, this study focused on individuals aged 65 and above. After excluding cases with missing data, 12,731 individuals were included in the final analysis. Various statistical methods including frequency analysis, t-tests, ANOVA, Scheffé test and hierarchical regression analysis were performed using SPSS 25.0 for windows. The statistical significance level (α) was set at .05. Results : The main results of this study were as follows. Firstly, dietary lifestyle exhibited variations depending on gender, age, education level, individual income, basic livelihood type, household type, self-rated health status, and chewing difficulty (p<.001). Secondly, there were disparities in health-related quality of life (as measured by the EQ-5D index) based on gender, age, education level, residence, individual income, basic livelihood security, self-rated health status, and chewing difficulty (p<.001). Thirdly, the EQ-5D index showed that elderly individuals' dietary lifestyle adversely impacted their health-related quality of life (F=353.74, p<.001). Conclusion : Therefore, it is necessary to prepare policies to improve the health-related quality of life by maintaining a proper diet for the elderly, and customized support and management is required taking into account the elderly's gender, age, education level, individual income, basic livelihood security, household type, self-rated health status, chewing difficulty etc.

• Journal of Korean society of Dental Hygiene
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• v.21 no.5
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• pp.595-600
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• 2021

Objectives: For postmenopausal women who participated in the 2019 National Health and Nutrition Examination Survey, we aimed to provide basic data for oral health management interventions and oral policies for each life cycle of postmenopausal women by identifying the relationship between physical activity and depression on oral health behavior and awareness symptoms. Methods: The participants of this study were 1,628 menopausal women, and their general characteristics, physical activity, depression, and oral health behavior and awareness symptoms were investigated. This study used the complex sample frequency analysis, complex sample 𝞆² test, and logistic regression analysis method, which is a sample design of the National Health and Nutrition Examination Survey. Results: The factors influencing physical activity were the use of oral hygiene device and chewing difficulty. and the influencing factors of depression experience were pain and chewing difficulty. Conclusions: As a result, physical activity and depression experience should be utilized by developing and oral health program for the promotion of oral health in postmenopausal women.

• Journal of Korean society of Dental Hygiene
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• v.23 no.5
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• pp.395-402
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• 2023

Objectives: This study aimed to identify factors related to oral health and depression in Korean adults and contribute to the development of a mental health program to improve depression through oral health management. Methods: Data was obtained from the 2021 Korean Community Health Survey. The chi-square test was used to determine the differences in depression experience relative to general participant characteristics and their oral health. To determine the odds ratio and 95% confidence interval, multiple logistic regression analysis was used. All statistical analyses were performed using the SAS software (version 9.4). Results: The results suggest that depression may be influenced by gender, age, household generation, drinking habits, subjective health level, moderate to high exercise, breakfast, high blood pressure, diabetes, subjective oral health level, chewing discomfort, and tooth brushing. An increasing level of depression was associated with decreasing subjective oral health level (1.34 times), uncomfortable chewing (3.08 times), and frequency of toothbrushing after lunch or before going to bed (1.23 times and 1.58 times, respectively). Conclusions: Our study confirmed a close relationship between oral health and mental health. In developing health programs for improving depression, appropriate oral health care should be considered.

• Journal of Oral Medicine and Pain
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• v.23 no.2
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• pp.127-141
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• 1998

This study was performed to investigate the clinical features of internal derangement of temporomandibular joint. For this study, 117 patients with temporomandibular disorders and 81 dental students without any signs and symptoms of temporomandibular disorders were selected as the patients group and as the control group, respectively. Preferred chewing side, Angle's classification, lateral guidance pattern, maximal mouth opening range, and affected side were recorded clinically. Head and shouldeer posture was measured in a groundplate on which square diagram of five centimeters each had been drawn, and cephalograph was also taken for measurement of head and neck posture. Sonopak of Biopak system (Bioresearch inc., USA) was used to record joint vibration for evaluation of internal healthy status of temporomandibular joint. The data collected were analyzed by SAS statistical program. The results of this study were as follows : 1. Frequency of left side chewing subjects was higher in patients than in control group, but there was no difference in distribution of subjects by Angle's classification. Other types was prvalent in patients whereas group function was more in control group for lateral guidance pattern. 2. As to lateral guidance pattern by clinical diagnosis, patients with internal derangement and/or degenerative joint disease showed higher frequency was consistent with the result by Sonopak impression. 3. There was no difference for shoulder height between the two groups, however, tilting of head and backward extension of cervical spine was more frequent in control group. 4. Acromion was positioned more anteriorly in patients with internal derangement and/or degenerative joint disease than in control group and angle between eye and tragus was larger in patients. Patients with degenerative joint disease showed more flexed head posture than control group did in cephalometric profile. 5. Maximal mouth opening range in patients with internal derangement was the least in all subgroups in patients classified by Sonopak impression.