• Title/Summary/Keyword: chemical laboratories

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The Management Actual Condition and Recognition of Material Safety Data Sheets in Dental Laboratories (치과기공소에서의 물질안전보건자료(MSDS) 인식 및 관리 실태)

  • Bae, Eun-Jeong
    • Journal of Technologic Dentistry
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    • v.32 no.3
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    • pp.221-232
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    • 2010
  • Purpose: It is necessary for dental technicians exposed to hazardous chemicals in the dental laboratories to be informed of the various harmful effects of chemicals for their health and safety. The purposes of this study was to investigate the actual condition of the use of MSDS in dental laboratories and the recognition rate of MSDS for dental technicians. Methods: 231 dental technicians who were self-written questionnaire. The results were analyzed by SPSS 12.0. The answers to the questionnaire underwent frequency analysis, chi-square test and correlation analysis were performed to investigate association between health effects and recognition rate of chemical information. Results: The results from the effects of damage caused by chemicals 60.7%, and when it was less than 2 years working experience 47.6%. Currently any dental laboratories(rooms) was not furnished MSDS(0%) and even similar data furnishing rate was only 17.3%. Answer rate of 'Do not know about MSDS' was 73.6%. In addition to, education in the types and characteristics of chemicals(74.5%) does not receive all the higher education. For the question of 'To prevent human risks and accidents, is to provide chemical information needed', the answer rate of 'needed' was 87.2%. Moreover, the answer rate of 'To provide chemical information that could prevent accidents' was 76.6%. Therefore it was found that dental technicians need to be provided for chemical information. In addition, they wanted to get education related to chemicals used in the workplace(80.5%), and 90.9% was answered that they was willing to keep MSDS in they workplace. Conclusion: This study investigated the current dental laboratories(rooms) and the MSDS for the awareness and recognition of workers was very low, education was not being conducted properly. The dental laboratories(rooms) of the compact characteristics of the MSDS was not reasonably accessible and the furnishing location, dental laboratories(rooms) for the real item was needed for improvement. MSDS for dental technicians through education and promotion of information about chemicals and chemicals was to prevent health problems caused by the MSDS that will raise awareness of the necessity.

Synthesis of Small Molecule-Peptide Conjugates as Potential Whitening Agents

  • Lee, Hye-Suk;Shin, Kyong-Hoon;Ryu, Geun-Seok;Chi, Gyeong-Yup;Cho, In-Shik;Kim, Han-Young
    • Bulletin of the Korean Chemical Society
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    • v.33 no.9
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    • pp.3004-3008
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    • 2012
  • Small molecule conjugated peptides were prepared by solid-phase synthesis as potential novel whitening agents, and their melanogenesis inhibitory activities were investigated. The conjugated small molecules were well-known materials as tyrosinase inhibitors, and peptides were selected from the sequences that are known to antagonize melanocortin receptor 1 (MC1R). Most of small molecules-peptide conjugates showed superior melanin inhibition activity to kojic acid and arbutin. Among these, almost all compounds have -AR- sequence. From this study, we concluded that the small molecule conjugated peptides containing -AR- sequence have melanogenesis inhibitory activities and have potential to be used as novel whitening agents.

Multiple Chemical Sensitivity in Chemical Laboratory Workers

  • Perez-Crespo, Juan;Lobato-Canon, Rafael;Solanes-Puchol, Angel
    • Safety and Health at Work
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    • v.9 no.4
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    • pp.473-478
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    • 2018
  • Background: Multiple Chemical Sensitivity (MCS) is an acquired disease which etiology remains unknown. It is characterized by the development of sensitivity to certain chemical products. Most of the hypotheses formulated to explain the syndrome associate it to a previous exposition to some kind of volatile chemical. University researchers in chemical laboratories suffer a phenomenon of multi-exposition to chemical agents at low concentration during long periods of time although in an irregular form. Many of these chemical agents have similar properties to those suspicious of causing MCS. This article studies the prevalence of MCS in laboratory researchers. Methods: The study group is university researchers in chemical laboratories. The control group was obtained from administrative personnel who work in the same universities and therefore, are not exposed to chemical products from the laboratories, but have the same exposition to the rest of environmental polluting agents from the area and from the buildings of the university. In this study, it is used the Quick Environmental Exposure and Sensitivity Inventory (QEESI) (sensitivity of 92%/specificity of 95%). Results: The results showed that the prevalence of MCS for the university researchers is not related to exposition by inhalation to multiple chemical agents, at low concentration. Conclusions: The results disagree with one of the main etiological hypotheses of MCS, which is based on the existence of hypersensitive people, who presents a response after prolonged expositions to very low concentrations during a long period of time.

4M 방식에 의한 화학실험실 위험성 평가 기법

  • Kim, Jong-In;Lee, Dong-Ho
    • Proceedings of the Safety Management and Science Conference
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    • 2008.04a
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    • pp.11-18
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    • 2008
  • This research modified the checklist used in the universities in USA, England and Korea considering the current situation of Korea, and conducted case studies upon each section of appointed chemical laboratories based on 4M criteria, which stands for Machine, Media, Man and Management. The purpose of the studies is to assess how dangerous the laboratories are and to contribute to prevention of accidentsin the laboratories as well as reducing loss of lives and property. The result of this research found out the harmful and hazardous factors based on the 4M-type checklist and predicted the dangerousness as it multiplies possible frequency by intensity. Protective equipment, safety facilities in laboratories, emergency exit and compressed gas cylinder are found to be more dangerous, so the result shows that it is desirable to improve ventilation, safety facilities and circumstances of the laboratory through the investment.

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