• Environmental Analysis Health and Toxicology
• /
• 제30권sup호
• /
• pp.7.1-7.10
• /
• 2015

Objectives For successful adoption of legislation controlling registration and assessment of chemical substances, it is important to obtain sufficient toxicological experimental evidence and other related information. It is also essential to obtain a sufficient number of predicted risk and toxicity results. Particularly, methods used in predicting toxicities of chemical substances during acquisition of required data, ultimately become an economic method for future dealings with new substances. Although the need for such methods is gradually increasing, the-required information about reliability and applicability range has not been systematically provided. Methods There are various representative environmental and human toxicity models based on quantitative structure-activity relationships (QSAR). Here, we secured the 10 representative QSAR-based prediction models and its information that can make predictions about substances that are expected to be regulated. We used models that predict and confirm usability of the information expected to be collected and submitted according to the legislation. After collecting and evaluating each predictive model and relevant data, we prepared methods quantifying the scientific validity and reliability, which are essential conditions for using predictive models. Results We calculated predicted values for the models. Furthermore, we deduced and compared adequacies of the models using the Alternative non-testing method assessed for Registration, Evaluation, Authorization, and Restriction of Chemicals Substances scoring system, and deduced the applicability domains for each model. Additionally, we calculated and compared inclusion rates of substances expected to be regulated, to confirm the applicability. Conclusions We evaluated and compared the data, adequacy, and applicability of our selected QSAR-based toxicity prediction models, and included them in a database. Based on this data, we aimed to construct a system that can be used with predicted toxicity results. Furthermore, by presenting the suitability of individual predicted results, we aimed to provide a foundation that could be used in actual assessments and regulations.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2009년도 제38회 동계학술대회 초록집
• /
• pp.473-473
• /
• 2010

Plasma is widely used in various commercial etchers and chemical vapor deposition. Unfortunately, real-time plasma process monitoring is still difficult. Some methods of plasma diagnosis is improved, however, it is possible for real-time plasma diagnosis to use non-intrusive probe only. In this research, the object is to investigate the suitability of using impedance analysis and optical emission spectroscopy (OES) for real-time plasma process monitoring. It is assumed that plasma system is a equivalent circuit. Therefore, V-I probe is used for measuring impedance, which can be a new non-intrusive probe for plasma diagnosis. From impedance data, we tried to analyse physical properties of plasma. And OES, the other method of plasma diagnosis, is a typical non-intrusive probe for analyzing chemical properties. The amount of the OES data is typically large, so this poses a difficulty in extracting relevant information. To solve this problem, principal component analysis (PCA) can be used. For fundamental information, Ar plasma and $O_2$ plasma are used in this experiment. This method can be applied to real-time endpoint and fault detections.

• Toxicological Research
• /
• 제17권
• /
• pp.237-239
• /
• 2001

China is an Asia country with population more than 1,200 millions. According to the national registration, the number Q[ chemicals commonly used in China reaches 80,000, and the number of chemicals produced in China is more than 30,000, about 10% of which has been evaluated for safety and has the toxicological data. Most of the chemicals still need safety evaluation and a part of chemicals need a renewed evaluation. At present. the information techniques and telecommunication network are develop-ing widely and intensively. It is used not only in different institutions and enterprises, but also in many governmental sectors in my country. Here is the introduction of the situation of information network on chemical safety with toxicological data and the work done by different institutions and governmental sectors in China.

• 한국환경보건학회지
• /
• 제46권4호
• /
• pp.410-422
• /
• 2020

Objectives: According to the Act on Registration, Evaluation, Etc. of Chemicals, new and existing chemicals must be registered by 2030. In addition, industries need to submit hazard data as an attachment during the registration process. Therefore, we constructed a nationwide chemical database to support small industry by providing hazard data and original sources. During the process, we developed a new standard procedure for minimizing errors and increasing reliability. Methods: We analyzed the categories of errors and the cause of the errors through the verification results of the 2019 project. We present an improved database construction methodology and system. Results: Errors are categorized according to their causative factors into simple, technical, and structural type errors. Simple errors arise simply because of decreased concentration or negligence in following the instructions. Technical errors are caused by a discrepancy between the professional field and the type of data. Structural errors indicate systemic errors such as incomplete forms on the excel database or ambiguity in the guidelines. Lessons from the errors collected in the 2019 project are used to update the procedures for database authorization and technical guidelines. The main update points are as follows; 'supplementation of review process', 'giving regular training to external reviewers', 'giving additional information to authors, like physico-chemical properties of substances, degradability, etc.', 'amendment of excel form', and 'guideline upgrades'. Conclusions: We conducted this study with the aim of improving the accuracy and reliability of the database of hazard information for chemical substances. The new procedures and guidelines are now being used in the 2020 project for construction of a hazard information database for Korea.

• 대한치과기공학회지
• /
• 제32권3호
• /
• pp.221-232
• /
• 2010

Purpose: It is necessary for dental technicians exposed to hazardous chemicals in the dental laboratories to be informed of the various harmful effects of chemicals for their health and safety. The purposes of this study was to investigate the actual condition of the use of MSDS in dental laboratories and the recognition rate of MSDS for dental technicians. Methods: 231 dental technicians who were self-written questionnaire. The results were analyzed by SPSS 12.0. The answers to the questionnaire underwent frequency analysis, chi-square test and correlation analysis were performed to investigate association between health effects and recognition rate of chemical information. Results: The results from the effects of damage caused by chemicals 60.7%, and when it was less than 2 years working experience 47.6%. Currently any dental laboratories(rooms) was not furnished MSDS(0%) and even similar data furnishing rate was only 17.3%. Answer rate of 'Do not know about MSDS' was 73.6%. In addition to, education in the types and characteristics of chemicals(74.5%) does not receive all the higher education. For the question of 'To prevent human risks and accidents, is to provide chemical information needed', the answer rate of 'needed' was 87.2%. Moreover, the answer rate of 'To provide chemical information that could prevent accidents' was 76.6%. Therefore it was found that dental technicians need to be provided for chemical information. In addition, they wanted to get education related to chemicals used in the workplace(80.5%), and 90.9% was answered that they was willing to keep MSDS in they workplace. Conclusion: This study investigated the current dental laboratories(rooms) and the MSDS for the awareness and recognition of workers was very low, education was not being conducted properly. The dental laboratories(rooms) of the compact characteristics of the MSDS was not reasonably accessible and the furnishing location, dental laboratories(rooms) for the real item was needed for improvement. MSDS for dental technicians through education and promotion of information about chemicals and chemicals was to prevent health problems caused by the MSDS that will raise awareness of the necessity.

• 디지털산업정보학회논문지
• /
• 제14권4호
• /
• pp.57-68
• /
• 2018

This paper presents a smart firefighting appliances monitoring system based on big data analytics platform using GS1 for Smart City. Typical firefighting appliances are fire hydrant, fire extinguisher, fire alarm, sprinkler, fire engine, etc. for the fire of classes A/B/C/D/E. Among them, the dry chemical fire extinguisher have been widely supplied and 6 millions ones were replaced for the aging ones over 10 years in the past year. However, only 5% of them have been collected for recycling of chemical materials included the heavy metals of environment pollution. Therefore, we considered the trace of firefighting appliances from production to disposal for the public open service. In the paper, we suggest 1) a smart firefighting appliances system using GS1, 2) a big data analytics platform and 3) a public open service and visualization with the analyzed information, for fire extinguishers from production to disposal. It can give the information and the visualized diagrams with the analyzed data through the public open service and the free Apps.

• 한국안전학회지
• /
• 제16권2호
• /
• pp.69-74
• /
• 2001

In this study, we analyzed the accident scenarios of chemical plants through the analysis of lots of chemical accidents and using experts knowledge, and looked into the method of prevention and response. Moreover, we developed a systemic and actual Emergency Response Plan Software(ERPS) that could prevent, prepare and respond totally for the chemical industry facilities using the data from the accident effect estimation from the local society and the geographic information of a chemical plant. The ERPS consists of the information for the plant and process, the consequence analysis and the ERPTA(Emergency Response Plan Tree Analysis). In conclusion, the program developed in this study could help effectively all the chemical industry facilities to prevent and respond to possible accidents.

• 한국가스학회지
• /
• 제2권2호
• /
• pp.48-54
• /
• 1998

본 연구에서는 주 시스템이라고 할 수 있는 안전관리정보시스템(SMIS Ver 1.0, Safety Management Information System)과 이에 대한 자료 관리를 위한 부 시스템(subsystem)인 데이터베이스들을 개발하였다. 기업의 안전관리 정보화는 관리적인 측면과 기술적인 측면이 함께 고려되어야 하나 본 연구의 안전관리정보시스템은 안전기술에 대한 정보화를 위해 기술적인 측면의 관련 요소들을 크게 4가지 모듈로 구분하여 구성하였다. 이들을 상호 연관시켜서 가스산업의 안전정보를 효율적으로 운영하고, 위험성을 평가하며, 그 결과를 안전운전지침이나 비상계획 수립에 반영할 수 있게 하였다. 그리고 안전관리정보시스템을 지원 할 수 있는 사고관련 자료, 물질자료 및 장치관련 자료 등에 대하여 3개의 모듈로 데이터베이스를 구성하였다. 이를 통하여 현장에 분산되어 있던 자료를 입력 검색하게 함으로써 보다 체계적으로 자료를 관리할 수 있게 하였다. 또한 개발된 프로그램을 사례적용을 통하여 검증한 결과, 자료의 검색 및 저장 등이 용이하고, 특히 데이터베이스와 안전관리정보시스템의 연계로 안전 정보를 활용하는 구조체계가 간소화되어 기존의 문서화 작업에 소요되었던 인력 및 시간이 절약됨을 알 수 있었다.

• 한국에너지공학회:학술대회논문집
• /
• 한국에너지공학회 1997년도 추계학술발표회 논문집
• /
• pp.17-23
• /
• 1997

A methodology for on-line data reconciliation and optimization has been proposed to minimize the energy cost of a utility system. As industrial data tend to be corrupted by noise or gross error, fast and robust data reconciliation technique is essential for the on-line optimization of utility system. Thus, we propose the hierarchical decomposition approach that can be applicable to on-line data reconciliation and optimization. As this approach divides whole system into several subsystems and removes the nonlinearity of constraint systematically, it handles complexity of system easily and shows good performance in accuracy and computation speed. Through case studies, we prove that this methodology is a good candidate for on-line data reconciliation and optimization.

• 한국산업보건학회지
• /
• 제30권3호
• /
• pp.280-291
• /
• 2020

Objectives: Hazard classification is a controversial issue in the new MSDS system in which chemical companies have to prepare and submit MSDS for chemicals that they manufacture or import to the competent authorities according to the amended Occupational Safety and Health Act. The aim of this study is to suggest how to apply and manage harmonized hazard classification criteria and results by investigating current hazard classification systems and trends. Methods: The domestic issues about different hazard classification criteria and results were investigated by reviewing the literature and business outcomes regarding KOSHA. We also checked official and unofficial reports from the UN to understand international discussion about the topic. Chemical hazard classification results from agencies providing chemical information were analyzed to compare a harmonized rate between classifications. Furthermore, a field survey of a few chemical companies was conducted. Results: Under the related competent authorities, an integrated standard proposal was developed to harmonize the domestic hazard classification criteria. Although harmonized chemical information is strongly needed, we recognized the uncertainty and difficulty of harmonized hazard classification from the UN global list project review. In practice the harmonization rate of the classification was generally low between the classification in KOSHA, MoE, and EU CLP. Among hazard classes, health hazards largely led the disharmony. The field survey revealed a change of perception that the main body of chemical information production is manufacturers. Approaches and solutions about hazard classification issues differed depending on business size, types of chemical handling, and other factors. Conclusions: We proposed reasonable ways by time and step to apply hazard classification in the new MSDS system. Chemical manufacturers should make and offer chemical information including responsible hazard classifications. The government should primarily accept these classifications, evaluate them by priority, and support or supervise workplaces in order to communicate reliable chemical information.