• 전자공학회논문지 IE
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• v.43 no.1
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• pp.39-45
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• 2006

The increment of user at mobile communication system requires the need of increased system capacity. To increase the system capacity can be realized by decreasing the size of cell. But, this method causes various problems. Therefore, it be used the hierarchical cellular system with macrocell and microcell for a efficient working. The users feel more inconvenience about the drop of connected call than the block of new call. Therefore, it is to be desired that the dropping rate of handoff call is lowered. At this paper, we use non reversible hierarchical scheme and fixed channel assignment scheme at the hierarchical cellular system with macrocell and microcell for the call process strategy. We analyze the system performance in accordance with the number of guard channel for handoff.

• Korean Journal of Biological Psychiatry
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• v.1 no.1
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• pp.40-59
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• 1994

The introduction of lithium salts for the treatment of mood disorder by Code in 1949 was a major therapeutic breakthrough. Yet it is far from the universal therpeutic agent in the treatment of mood disorders. Indeed, some acutely manic patients do not respond adeqately to lithium and some individuals experience breakthrough affective episodes during lithium maintenance. In the last decode, it has become c1ear that a significant number of patients with more highly recurrent disorders may require alternative or enhanced forms of prophylactic treatment. For these reasons, a variety of other drugs hove been employed for the treatment and prophylaxis of mood disorders. Efforts to develop new pharmacologic strategies for mood disorder hove included a diverse array of medications, ranging from potent benzodiazepines to novel neuroleptics and from anticonvulsants to calcium channel blockers. The anticonvulsants appear particularly useful in cases of dysphoric mania and rapid cycling state, subforms of bipolar disorder that respond quite poorly to conventional treatments. Among all of these new pharmacologic strategy, carbamazepine and sodium valproate have received the broadest clinical applications as maintenance therapies. The data documenting the short-term antimanic effectiveness of the calcium channel blocker verapamil and benzodiazepins such as clonazepam and lorazepam appear also promising. A number of other theoretically interesting, as well as clinically relevant therapies, which are not presently employed routinly, hove also been studied, including 2 blocker clonidine, atypical antipsychotic clozapine, cholinomimetics, 5-HT enhancers, thyroid and magnesium preparations. Now prophylaxis in mood disorder remains a considerable therapeutic challenge. Controlled testing of the prophylactic efficacy of compounds such as carbamazepine, valproic acid, and the calcium channel blockers represent important next step in the clinical trials for mood disorder.

• International Journal of Air-Conditioning and Refrigeration
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• v.7
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• pp.1-10
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• 1999

In this study, a numerical analysis is made on the ice-formation for laminar water flow inside a stenotic tube. The study takes into account the interaction between the laminar flow and the stenotic port in the circular tube. The purpose of the present numerical investigation is to assess the effect of a stenotic shape on the instantaneous shape of the flow passage during freezing upstream/downstream of the stenotic channel. In the solution strategy, the present study is substantially distinguished from the existing works in that the complete set of governing equations in both the solid and liquid regions are resolved. In a channel flow between parallel plates, the agreement between the of predictions and the available experimental data is very good. Numerical analyses are performed for parametric variations of the position and heights of stenotic shape and flow rate. The results show that the stenotic shape has the great effect on the thickness of the solidification layer inside the tube. As the height of a stenosis grows and the length of a stenosis decreases, the ice layer thickness near the stenotic port is thinner, due to backward flow caused by the sudden expansion of a water tunnel. It is found that the flow passage has a slight uniform taper up to the stenotic channel, at which a sudden expansion is observed. It is also shown that the ice layer becomes more fat in accordance with its Reynolds number.

• Journal of The Korean Society of Clinical Toxicology
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• v.13 no.2
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• pp.103-110
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• 2015

Purpose: The purpose of this study is to evaluate the effectiveness and the adverse events of high dose insulin/euglycemia therapy in acute calcium channel blocker (CCB) poisoning. Methods: We developed a systematic search strategy and applied it to 4 electronic reference databases. We searched medical journals as well as the bibliographies of relevant articles. All forms of literature relevant to human use of high dose insulin for acute CCB poisoning were included. The literature search was conducted by two investigators in August, 2015 with publication language restricted to English and Korean. Case reports were divided between CCB overdose alone and multi-drug overdose including CCB. The effect and adverse event of high dose insulin and clinical outcome of each case were analyzed. Results: Among 55 searched studies, 20 studies were included. A prospective study, a retrospective study, a systematic review study, and 17 case reports were identified. Case reports consisted of 11 CCB alone and 12 multidrug overdose cases including CCB. Although most cases described significant clinical improvements, one of them showed no beneficial effect. Several adverse events including hypoglycemia and hypokalemia were reported. No significant sequalae from adverse events was reported. Conclusion: Although there were many case reports demonstrating successful use of high dose insulin for CCB poisoning, the effect cannot be estimated due to a possibility of publication bias. Therefore, high dose insulin/euglycemia therapy might be considered adjunctive therapy in cases of CCB intoxication refractory for standard therapy.

• Korean journal of communication and information
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• v.49
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• pp.39-56
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• 2010

This study on the exposed the viewers diversity as a basic cable television service. Diversity is the most basic goal of broadcasting policy has important implications. But still, such as cable and pay-media research on the viewing diversity has made a limited basis. SO much to offer for the cable offers viewers receive the number of channels available to compare the diversity of the field was verified. Price rises of analysis for the cable the more the number of channels offered to supply the channel has increased the diversity of the field. SO granted in accordance with the results of a market strategy, but for a variety of channels to be provided by a policy perspective, the price depending on the choice of a variety of audiences can be quite limited means. That is a wide range of viewers watching the channel had a right to be limited. These phenomena to improve the pay television service and the need to manage the Product channel diversity index was raised.

• Management & Information Systems Review
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• v.39 no.3
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• pp.127-140
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• 2020

This study conducted analysis of YouTube channels by domestic companies as the marketing strategies of domestic companies vary due to the rapid growth of the Internet and YouTube channels. The YouTube channel analysis analyzed the number of subscribers, plays, videos and classifications of domestic companies on YouTube channels, the top 100 domestic companies in the YouTube ranking site "Company/Official. The analysis showed that 4.53 million companies had the largest number of subscribers, Samsung mobile, 544.69 million circuit Samsung mobile, and 11,416 League of Legends-Korea channels had the largest number of videos. The most product classification showed that food/dining companies were engaged in a lot of YouTube activities. The use of YouTube, which is rapidly growing in companies through analyzing YouTube channels from the perspective of a company's new marketing strategy, is a new tool for integrated marketing communications. It is expected that the YouTube channel, which enables two-way communication of companies' marketing strategies, will be used as basic data when producing YouTube content in the future.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.1
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• pp.87-94
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• 2021

Skin photoaging occurs due to chronic exposure to solar ultraviolet radiation (UV), the main factor contributing to extrinsic skin aging. Clinical signs of photoaging include the formation of deep, coarse skin wrinkles and hyperpigmentation. Although melanogenesis and skin wrinkling occur in different skin cells and have different underlying mechanisms, their initiation involves intracellular calcium signaling via calcium ion channels. The ORAI1 channel initiates melanogenesis in melanocytes, and the TRPV1 channel initiates MMP-1 production in keratinocytes in response to UV stimulation. We aimed to develop a drug that may simultaneously inhibit ORAI1 and TRPV1 activity to help prevent photoaging. We synthesized nootkatol, a chemical derivative of valencene. TRPV1 and ORAI1 activities were measured using the whole-cell patch-clamp technique. Intracellular calcium concentration [Ca2+]i was measured using calcium-sensitive fluorescent dye (Fura-2 AM). UV-induced melanin formation and MMP-1 production were quantified in B16F10 melanoma cells and HaCaT cells, respectively. Our results indicate that nootkatol (90 μM) reduced TRPV1 current by 94% ± 2% at -60 mV and ORAI1 current by 97% ± 1% at -120 mV. Intracellular calcium signaling was significantly inhibited by nootkatol in response to ORAI1 activation in human primary melanocytes (51.6% ± 0.98% at 100 μM). Additionally, UV-induced melanin synthesis was reduced by 76.38% ± 5.90% in B16F10 melanoma cells, and UV-induced MMP-1 production was reduced by 59.33% ± 1.49% in HaCaT cells. In conclusion, nootkatol inhibits both TRPV1 and ORAI1 to prevent photoaging, and targeting ion channels may be a promising strategy for preventing photoaging.

• Journal of Mushroom
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• v.22 no.3
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• pp.122-127
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• 2024

This study was conducted to evaluate the market potential of 'Hwanggeumsantari', a new oyster mushroom variety developed in Gyeonggi Province in 2019, and to derive effective market entry strategies. To objectively assess the marketability of 'Hwanggeumsantari' from various perspectives, a panel of 50 consumers was formed, and surveys and interviews were conducted. Additionally, two Focus Group Interviews were held with distributors in the agri-food sector. The results showed that potential consumers were positive about the color and texture of 'Hwanggeumsantari', but expressed relatively less satisfaction with its shelf life and aroma. Distributors, through tow Focus Group Interviews, evaluated that the product had sufficient market competitiveness, but called for efforts to improve cultivation techniques and enhance price competitiveness. Based on the results of market evaluations by consumers and distributors, a SWOT analysis was conducted. The main strengths identified were its outstanding color and texture, while the main weakness was its freshness issue. Meanwhile, the growing demand for healthy foods and various online sales channels could provide market entry opportunities for 'Hwanggeumsantari', but high sensitivity to price in the case of premium pricing could pose a threat. Consequently, a market entry strategy for 'Hwanggeumsantari' was proposed using a 4P mix approach based on the SWOT analysis results. The product strategy emphasized premium positioning, small packaging, and the development of packaging technology to maintain freshness. The price strategy proposed premium pricing and the operation of incentive programs. The distribution strategy suggested channel diversification, direct stores, or direct sales, while the promotion strategy emphasized storytelling and collaboration with influencers.

• Archives of design research
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• v.18 no.4 s.62
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• pp.205-214
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• 2005

The purpose of this study is to find an efficient marketing strategy in terms of media channel communications using one specific case study. Results of previous studies have shown that consumers' exposure to TV, newspaper, radio and magazine related to description of corporate image tends to be influential for consumers' product image, which mainly consists of product preference, expertise, and credibility. It means that media strategy should be different, depending on what kinds of image they try to be purposive. In conclusion, we concluded that TV and radio should be the best vehicle for increasing consumers' positive preference rather than those of newspaper and magazine. Newspaper and magazine are also influential in terms of expertise, and newspaper and magazine should be better than TV and radio in terms of credibility. The results of this study should be similar to previous studies in that TV and radio should be more inducing interest, and print media should be more credible than TV and radio.

• Strategy21
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• s.39
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• pp.114-139
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• 2016

Korea and China are neighboring countries with close contacts in many areas from long time ago, and have shared interests in maintaining peace and stability on the Korean Peninsula, and in deepening economic relationship which has been mutually complementary in their nature. Therefore their bilateral relations has been developed at a remarkable pace to the extent that it can't be better than now. However, the differences in their responses to North Korean nuclear test and ensuing long-range ballistic missile test-fire and the Chinese strong concern on the possible deployment of THAAD (Terminal High Altitude Air Defence) anti-missile system in Korea show that there are some weaknesses in their relations. For example, Korea is not still confident that China would fully implement the sanction measures contained in the UNSC resolution and I argue that Chinese proposal of parallel negotiation of the denuclearization and the replacement of Korean armistice with the Peace Agreement is not much persuasive. In THAAD issue, if Korea comes to conclusion in the future that THAAD is the most effective way to counter North Korean threats, Korea should make every efforts to assure China that Korea-US alliance is not targeting China, and the THAAD is a defensive system, not damaging Chinese security. In the longer-term, deepening strategic distrust and competition between the US and China in this part of East Asia, changing nature of economic cooperation between Korea and China, and the revival of 'great country mentality' by Chinese people together with the rising nationalism in both Korea and China would cast shadow on Korea-China relation in the years ahead, unless properly handled. In this regard, I suggest that the security communications between the two countries be further strengthened, and the tri-lateral dialogue channel be established among the three countries of Korea, the US and China, particularly on North Korean issues. I also suggest the new pattern of economic cooperation be sought, considering the changing economic environment in China, while strengthening the efforts to understand each other through more interactions between the two peoples.