• Title/Summary/Keyword: chamber method

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A Study on Subchronic Inhalation Toxicity of Isoprene Using Sprague-Dawely Rats (Isoprene 아급성 흡입독성 연구)

  • Chung, Yong Hyun;Lee, Sung Bae;Han, Jeong Hee;Kang, Min Gu;Kim, Jong Kyu;Rim, Kyung Taek;Yang, Jung Sun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.21 no.2
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    • pp.73-81
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    • 2011
  • The purpose of this study was to obtain scientific information regarding classification and health hazards that may result from a 13 weeks inhalation exposure of isoprene in Sprague-Dawley (SD) rats. The testing method was conducted in accordance with OECD guidelines for the testing of chemicals No. 413. The Rats were divided into 4 groups (10 male and 10 female rats in each group) and exposed to 0, 360, 1,620, 7,300 ppm isoprene in each exposure chamber for 6 h/day, 5 days/week, for 13 weeks. As a result, there were no mortality or abnormality during the period of study and did not show any significant changes of body weight. There were no dose response changes in urinalysis, hematological and serum biochemical value examination. Relative organ weight was increased significantly the right kidney in 7,300 ppm group of male rats. In female rats, relative organ weight of the left kidney and the both lungs in 1,620 ppm group and the left lung and the both kidneys in 7,300 ppm group were increased significantly. But the histopathological findings did not reveal any exposure-related changes. According to the above results, the no observable adverse effect level (NOAEL) of isoprene was 7,300 ppm (20.3 mg/L) in both male and female rats. In conclusion, Isoprene was not classified specific target organ toxicity of the 'Standard for Classification and Labeling of Chemical Substance and Material Safety Data Sheet' (Ministry of Employment and Labor, 2009).

Superhard SiC Thin Films with a Microstructure of Nanocolumnar Crystalline Grains and an Amorphous Intergranular Phase

  • Lim, Kwan-Won;Sim, Yong-Sub;Huh, Joo-Youl;Park, Jong-Keuk;Lee, Wook-Seong;Baik, Young-Joon
    • Corrosion Science and Technology
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    • v.18 no.5
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    • pp.206-211
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    • 2019
  • Silicon carbide (SiC) thin films become superhard when they have microstructures of nanocolumnar crystalline grains (NCCG) with an intergranular amorphous SiC matrix. We investigated the role of ion bombardment and deposition temperature in forming the NCCG in SiC thin films. A direct-current (DC) unbalanced magnetron sputtering method was used with pure Ar as sputtering gas to deposit the SiC thin films at fixed target power of 200 W and chamber pressure of 0.4 Pa. The Ar ion bombardment of the deposited films was conducted by applying a negative DC bias voltage 0-100 V to the substrate during deposition. The deposition temperature was varied between room temperature and $450^{\circ}C$. Above a critical bias voltage of -80 V, the NCCG formed, whereas, below it, the SiC films were amorphous. Additionally, a minimum thermal energy (corresponding to a deposition temperature of $450^{\circ}C$ in this study) was required for the NCCG formation. Transmission electron microscopy, Raman spectroscopy, and glancing angle X-ray diffraction analysis (GAXRD) were conducted to probe the samples' structural characteristics. Of those methods, Raman spectroscopy was a particularly efficient non-destructive tool to analyze the formation of the SiC NCCG in the film, whereas GAXRD was insufficiently sensitive.

An Experimental Study on Pressure Loss in Straight Cooling Channels (직선형 냉각채널에서의 압력손실에 대한 실험적 연구)

  • Yoon, Wonjae;Ahn, Kyubok;Kim, Hongjip
    • Journal of the Korean Society of Propulsion Engineers
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    • v.20 no.4
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    • pp.94-103
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    • 2016
  • A regeneratively-cooled channel in a liquid rocket engine is used to effectively cool a combustion chamber inner wall from hot combustion gas, and the heat transfer/pressure loss characteristics should be predicted in advance to design cooling channels. In the present research, five cooling channels with different geometric dimensions were designed and the channels were respectively manufactured using cutter and endmill. By changing coolant velocity and downstream pressure, the effects of manufacturing method, channel shape, and flow condition on pressure losses were experimentally investigated and the results were compared with the analytical results. At same channel shape and flow condition, the pressure loss in the channel machined by the cutter was lower than that by the endmill. It was also found that the pressure loss ratio between the experimental result and the analytical data changed with the channel shape and flow condition.

Investigation concerning Design Method of the Diffuser Expansion Ratio Commanding a Starting of the Second Throat Exhaust Diffuser for High Altitude Simulation (고도모사용 2차목 디퓨져 시동을 위한 디퓨져 팽창비 설계기법에 관한 연구)

  • Park, Sung-Hyun;Park, Byung-Hoon;Lim, Ji-Hwan;Yoon, Woong-Sup
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2008.11a
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    • pp.299-304
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    • 2008
  • Starting characteristics of the axi-symmetric second throat exhaust diffuser (STED) with zero-secondary flows are numerically investigated. Renolds-Average Navier-Stokes equations with a standard ${\kappa}-{\varepsilon}$ turbulence model incorporated with enhanced wall treatment are solved to simulate the diffusing evolutions of the nozzle plume. Minimum (optimum) starting pressure difference of 20$\sim$25% between 1-D theory and the measured data validated from previous results[5] is also applied to predict the range of an effective diffuser expansion ratio (Ad/At) in this system.

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Effect of pre-operative medication with paracetamol and ketorolac on the success of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a double-blind randomized clinical trial

  • Kumar, Umesh;Rajput, Akhil;Rani, Nidhi;Parmar, Pragnesh;Kaur, Amandeep;Aggarwal, Vivek
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.21 no.5
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    • pp.441-449
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    • 2021
  • Background: The efficacy of local anesthesia decreases in patients with symptomatic irreversible pulpitis. Therefore, it was proposed that the use of premedication with an anti-inflammatory drug might increase the success rate of pulpal anesthesia in mandibular posterior teeth with vital inflamed pulp. Methods: One hundred thirty-four patients who were actively experiencing pain willingly participated in this study. The Heft Parker (HP) visual analog scale (VAS) was used to record the initial pain intensity. Patients were randomly allocated to receive a placebo, 10 mg of ketorolac, and 650 mg of paracetamol. The standard inferior alveolar nerve block (IANB) was administered to all patients using 2% lidocaine with 1:200,000 adrenaline after one hour of medication. After 15 min, the patient was instructed to rate the discomfort during each step of the treatment procedure, such as access to remaining dentin, access to the pulp chamber, and during canal instrumentation on the HP VAS. IANB was considered successful if the patient reported no or mild pain during access preparation and instrumentation. Moderate or severe pain was classified as a failure of IANB and another method of anesthesia was used before continuing the treatment. Results: The rate of successful anesthesia in the placebo, paracetamol, and ketorolac groups was 29%, 33%, and 43%, respectively, and no statistically significant difference was found between the groups. Conclusion: Preoperative administration of paracetamol or ketorolac did not significantly affect the success rate of IANB in patients with irreversible pulpitis. No significant difference was observed between the paracetamol and ketorolac groups.

Ratio of Elemental Carbon Concentrations for Respective Measurement Locations according to the Sampler (샘플러에 따른 측정 위치별 원소탄소의 농도 비율)

  • Cha, Won-Seok;Kim, Eun-Young;Choi, Sung-Won;Choi, Soo-Yeon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.31 no.4
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    • pp.461-472
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    • 2021
  • Objectives: This study was conducted to determine the differences in EC concentrations according to the type of sampler by measuring and analyzing EC. Methods: Elemental carbon was measured in diesel engine vehicles and at the roadside. Using NIOSH method 5040, a cassette was coupled to 37 mm and 27 mm quartz filters and measurements were performed 21 times. There were 14 types of measurement methods, and polystyrene, polypropylene, and metal samplers were evenly placed inside the movable chamber. Results: The results measured using the 37 mm conductive cassette (closed/open) and the IOM sampler made of conductive materials showed a higher ratio than the other results. When the 37 mm conductive cassette was measured with the lid open, it showed a statistically significantly higher ratio than with other measurement methods (p<0.05). Conclusions: Checking the EC concentration a total of 21 times at each ratio based on the concentration of the 3-stage polystyrene cassette, it was statistically significantly higher when the 37 mm conductive cassette was open. This same cassette also showed a slightly higher EC concentration when closed. It was ascertained that some DEE was collected on the cassette wall surface due to the electrical conductivity of the polystyrene cassette, resulting in sample loss. Since EC is composed of fine particles, it is thought that electrical conductivity may affect its concentration.

Research on the Surface Improvement of High Soft Ground Using Calibration Chamber Test (모형토조실험에 의한 초연약지반의 표층개량에 관한 연구)

  • Bang, Seongtaek;Yeon, Yongheum
    • Journal of the Korean GEO-environmental Society
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    • v.20 no.5
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    • pp.39-46
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    • 2019
  • Most of the soil used for reclamation is marine clay generated from dredging construction.The soft ground made of dredged clay has high water content and high compressibility, so the bearing capacity of the ground is very weak and it is difficult to enter the ground improvement equipment. Therefore, surface hardening treatment method is used to enter equipment prior to full-scale civil engineering work, and stabilizer is mainly used for cement series. Cement-based stabilizers have the advantage of improving the ground in a short period of time and have excellent economic efficiency, but they are disadvantageous in that they cause environmental problems due to leaching of heavy metals such as hexavalent chromium. In this study, environmental effects evaluation of dredged clay mixed with normal portland cement and environmentally friendly stabilizer was evaluated, and uniaxial compressive strength test and indoor model test were conducted to confirm the bearing capacity characteristics of the solidified layer.

C-shaped root canals of mandibular second molars in a Korean population: a CBCT analysis

  • Kim, Hee-Sun;Jung, Daun;Lee, Ho;Han, Yoon-Sic;Oh, Sohee;Sim, Hye-Young
    • Restorative Dentistry and Endodontics
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    • v.43 no.4
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    • pp.42.1-42.7
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    • 2018
  • Objectives: The purpose of this study was to investigate the C-shaped root canal anatomy of mandibular second molars in a Korean population. Materials and Methods: A total of 542 teeth were evaluated using cone-beam computed tomography (CBCT). The canal shapes were classified according to a modified version of Melton's method at the level where the pulp chamber floor became discernible. Results: Of the 542 mandibular second molars, 215 (39.8%) had C-shaped canals, 330 (53%) had 3 canals, 17 (3.3%) had 2 canals, 12 (2.2%) had 4 canals, and 8 (1.7%) had 1 canal. The prevalence of C-shaped canals was 47.8% in females and 28.4% in males. Seventy-seven percent of the C-shaped canals showed a bilateral appearance. The prevalence of C-shaped canals showed no difference according to age or tooth position. Most teeth with a C-shaped canal system presented Melton's type II (45.6%) and type III (32.1%) configurations. Conclusions: There was a high prevalence of C-shaped canals in the mandibular second molars of the Korean population studied. CBCT is expected to be useful for endodontic diagnosis and treatment planning of mandibular second molars.

Numerical Simulation of Cone Penetration Tests in Sand Ground Using Critical State Mohr Coulomb Plasticity Model (한계상태 Mohr Coulomb 소성 모델을 활용한 콘관입시험의 수치적 모사)

  • Woo, Sang Inn;Chung, Choong-Ki
    • Journal of the Korean Geotechnical Society
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    • v.35 no.2
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    • pp.37-51
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    • 2019
  • This study focuses on the numerical simulations of the cone penetration tests in a sand ground. The mechanical responses of sand were described using the modified Mohr Coulomb plasticity model based on the critical state soil mechanics. In the plasticity model, the dilatancy angle was not a constant, but a function of the distance to the critical state line from the current state of void ratio and mean effective stress. To simulate cone penetration tests numerically, this study relied on Lagrangian finite element method under the axisymmetric condition. To enable penetration of the cone penetrometer without tearing elements along the symmetric axis, the penetration guide concept was adopted in this study. The results of numerical simulations on the calibration chamber cone penetration tests had good agreement with the experimental results.

Effects of Density, Temperature, Size, Grain Angle of Wood Materials on Nondestructive Moisture Meters

  • Pang, Sung-Jun;Jeong, Gi Young
    • Journal of the Korean Wood Science and Technology
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    • v.47 no.1
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    • pp.40-50
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    • 2019
  • The aim of this study was to investigate the effects of density, temperature, size, and grain direction on measurement of moisture contents (MC) of wood materials non-destructively. The MC of different sizes of solid wood, glulam, and CLT from larch (larix kaempferi, $560kg/m^3$) and pine (pinus koraiensis, $430kg/m^3$) were measured using the dielectric type and resistance type meters. The specimens were conditioned in the environmental chamber to be equilibrium moisture content (EMC) of 12 % and 19 %. When density setting in dielectric type meter was increased from $400kg/m^3$ to $600kg/m^3$, the MCs of specimen (S-L-100-E) were decreased from 13.4 % to 11.3 %. However, when wood group (WG) setting in resistance type meter was changed from WG1 to WG4, the measured MCs were increased from 9.2 % to 12.3 %. When temperature setting in resistance type meters was changed from 0 to $35^{\circ}C$, the MC was decreased from 17.0 % to 13.0 %. The MCs measured by dielectric type meter for larger specimens (S-L-100-E_11.3 %, G-L-240-E_11.7 % and C-L-120-E_12.8 %) were higher than those of small size specimens (S-L-30-E_8.7 %, G-L-150-E_10.3 %, and C-L-90-E_9.7 %). The MCs measured by resistance type meter for larger specimens (G-L-240-E_11.6 % and C-L-120-E_13.3 %) were also higher than those of small size specimens (G-L-150-E_10.4 %, and C-L-90-E_11.8 %). The resistance type meter was not affected by the grain direction but the dielectric type meter were affected by the grain direction. The MC measured by resistance type meter for G-L-120-E perpendicular to grain direction was 11.5 % and the measured MC parallel to grain direction was 11.3 %. The MC measured by dielectric type meter parallel to grain direction (12.1 %) was higher than that measured perpendicular to grain direction (10.7 %).