• 한국안광학회지
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• 제10권4호
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• pp.347-355
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• 2005

색본 연구에서는 중심이 차폐된 광학계를 고려하여 중심차폐와 입사광의 가우시안 진폭의 단락된 정도에 따른 광학계의 성능을 평가하기 위해 중심 spot 분포와 에너지 분포를 조사하였다. 광학계에서 중앙 차폐 반경의 크기가 증가함에 따라 상면에서 중심 spot의 반경은 점점 작아지며, 가우시안 진폭의 단락된 정도가 증가할수록 상면에서 중심 spot의 반경은 증가하였다. 또한 광학계의 중앙 차폐된 영역과 가우시안 진폭의 단락된 정도가 증가할수록 초점이동에 따른 초점심도는 증가하였으며, 중심 spot에서의 encircled energy는 감소되었다. 이러한 결과로부터 중앙 차에가 증가할수록 가우시안 인자의 영향이 작음을 알 수 있었다. 이러한 연구결과는 대구경 반사광학계의 개발에 사용될 것이다.

• Korea-Australia Rheology Journal
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• 제16권2호
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• pp.63-73
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• 2004

Flow in a channel with an obstruction at the entry can be reverse, stagnant or forward depending on the position of the obstruction. These flow phenomena have potential applications in the control of energy and various flows in process engineering. Parameters that affect this flow inside and around the test channel are the gap (g) between the obstruction geometry and the test channel, the Reynolds number (Re) and the length (L) of the test channel. The influence of these parameters on the flow behavior was investigated using a flat plate obstruction at the entry of the channel. A low concentration polyacrylamide solution (0.018% by weight) showing a powerlaw fluid behavior was used as the fluid in this investigation. The flow phenomena were investigated by the velocity measurement and the flow visualization and their results were compared with numerical simulation. These results of low concentration polyacrylamide solution are also compared with the results of water published elsewhere (Kabir et al., 2003). The maximum reverse flow inside the test channel observed was 20% - 30% of the outside test channel velocity at a g/w (gap to width) ratio of 1 for Reynolds numbers of 1000 to 3500. The influence of the test channel length (L) and the Reynolds number (Re) on the velocity ratio ($V_i$/$V_o$: inside velocity/outside velocity in the test channel) are also presented and discussed here.

• Tuberculosis and Respiratory Diseases
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• 제64권4호
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• pp.272-277
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• 2008

연구배경: 중심성 기도폐쇄를 동반하는 진행성 폐암환자에서 기도폐쇄를 호전시키기 위해 다양한 중재적 시술 Tuberculosis and Respiratory Diseases Vol. 64. No. 4, Apr. 2008277방법들이 시도되고 있으며, 이러한 시술방법 중 최근 굴절성 cryoprobe를 이용한 냉동치료가 국내에서도 시도되고 있다. 방법: 냉동치료 기계는 cryomachine과 cryoprobe로 구성되며, 냉매로는 아산화질소(N2O)를 사용하였다. 굴곡경 기관지내시경의 working chanel을 통해 굴절성 cryoprobe를 악성종양의 중심에 위치한 후 급속 냉동($-89^{\circ}C$)하여 악성 종양 조직을 냉동 시킨 후 stalk을 puling하여 제거하거나 급속 냉동과 해동 과정을 반복하였다. 결과: 중심성 기도폐쇄가 발생한 진행성 폐암 환자 4명에게 냉동치료를 시술하였다. 3명의 환자에서 성공적으로 기도폐쇄를 유발하는 종양을 제거하였으며, 그 후 호흡곤란 및 무기폐 소견이 호전되었다. 1명의 환자에서 기관지 천공으로 인한 종격동 기종이 발생하였으며 또 다른 환자에서 냉동치료 도중 대량 출혈이 발생하였으나 응급 조치 후 다시 회복되었다.

• Tuberculosis and Respiratory Diseases
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• 제68권1호
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• pp.6-9
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• 2010

Background: The efficacious use of interventional bronchoscope for patients with central airway obstruction due to malignant or benign lesions has been proven. Among many therapeutic bronchoscopic procedures, endobronchial cryotherapy is an established recanalization method for the obstruction of the respiratory tract. Recently, the use of this procedure has been increasing in Korea. However, limited data are available in the literature regarding its efficacy in Korea. Methods: Thirty patients, who had been treated with a flexible cryoprobe for cryotherapy were enrolled; clinical characteristics and treatment outcomes were analyzed. The patients had been treated with the technique using nitrous oxide as a cryogen under local anesthesia. Objective outcomes were 3 different degrees of therapeutic success by use of follow-up bronchoscopic findings as follows: successful, partially successful, and unsuccessful response. Subjective outcomes were evaluated as an improvement in symptoms. Results: The mean age of enrolled patients was $59{\pm}11$ years and there was a male (22/30) dominance. Twenty-three patients had malignant tumor and 7 patients had benign lesions with central airway obstruction. Successful recanalization was achieved in 11 (37%) patients, and partially successful response was achieved in 15 (50%) patients. Dyspnea was improved in 84.2% (16/19) of patients. At least one respiratory symptom was resolved in 91.3% (21/23) patients. Seven patients (23.3%) needed additional bronchoscopic electrocautery because of the bleeding as a complication of cryotherapy. Conclusion: Endobronchial cryotherapy is an effective and less expensive procedure for the management of central airway obstruction. However, the procedure should be performed under the preparing for an emergency situation, such as massive bleeding.

• Journal of Mechanical Science and Technology
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• 제17권6호
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• pp.879-887
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• 2003

The flow in a parallel walled test channel, when obstructed with a geometry at the entrance, can be forward, reverse and stagnant depending on the position of the obstruction. This interesting flow phenomenon has potential benefit in the control of energy and various flows in the process industry In this experiment, the flat plate obstruction geometry was used as an obstruction at the entry of the test channel. The parameters that influence the flow inside and around the test channel were the gap (g) between the test channel and the obstruction geometry, the length (L) of the test channel and the Reynolds number (Re). The effect of the gap to channel width ratio (g/w) on the magnitude of the velocity ratio (V$\_$i/ / V$\_$o/ : velocity inside/ velocity outside the test channel) was investigated for a range of Reynolds numbers. The maximum reverse flow observed was nearly 20% to 60% of the outside velocity for Reynolds number ranging from 1000 to 9000 at g/w ratio of 1.5. The maximum forward velocity inside the test channel was found 80% of the outside velocity at higher g/w ratio of 8. The effect of the test channel length on the velocity ratio was investigated for different g/w ratios and a fixed Reynolds number of 4000. The influence of the Reynolds number on the velocity ratio is also discussed and presented for different gap to width ratio (g/w). The flow visualisation photographs showing fluid motion inside and around the test channel are also presented and discussed.

• Journal of Advanced Marine Engineering and Technology
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• 제35권7호
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• pp.921-929
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• 2011

We measured experimentally the properties of fluid dynamics, velocity fields, and the pressure, around stenotic obstruction located inside a circular channel structure. Particle image velocimetry system was employed to obtain velocity fields at the central section of the circular channel in the streamwise direction. The stenosis model used was made of acrylic material with different stenotic aspect ratios. The working fluid was water and it was returned by a centrifugal pump system. Pressure measurements were carried out to validate the effect of a narrow passageway. Results showed that the acceleration of gap flow through stenotic obstruction and the pressure drop in the recirculation regime behind the stenosis model can be observed.

• 대한기관식도과학회지
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• 제4권1호
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• pp.122-126
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• 1998

Laryngomalacia is the most common cause of inspiratory stridor and varying degrees of airway obstruction in infants but rarely occurs in children or adults. However, acquired airway obstruction would be developed due to the presence of redundant mucosa in the aryepjglottic folds similar to that seen in congenital laryngomalacia after central nervous system damage. To this condition, the term“Neurasthenic Laryngomalacia”is applied. We have recently experienced a case of neurasthenic larygomalacia, which has been managed by laser aryepiglottoplasty with good result. We report management and outcome of this patient with a review of the literatures.

• Tuberculosis and Respiratory Diseases
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• 제42권5호
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• pp.787-792
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• 1995

저자 등은 우측 늑막삼출과 간암을 동반하고 드물게 보이는 심막 횡격 정맥의 측부 순환을 동반한 신정맥 상부에서 하대정맥 폐쇄 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Clinical Endoscopy
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• 제57권3호
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• pp.375-383
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• 2024

Background/Aims: Endoscopic self-expandable metal stent (SEMS) placement is currently the standard technique for treating unresectable malignant distal biliary obstructions (MDBO). Therefore, covered SEMS with longer stent patency and fewer migrations are required. This study aimed to assess the clinical performance of a novel, fully covered SEMS for unresectable MDBO. Methods: This was a multicenter single-arm prospective study. The primary outcome was a non-obstruction rate at 6 months. The secondary outcomes were overall survival (OS), recurrent biliary obstruction (RBO), time to RBO (TRBO), technical and clinical success, and adverse events. Results: A total of 73 patients were enrolled in this study. The non-obstruction rate at 6 months was 61%. The median OS and TRBO were 233 and 216 days, respectively. The technical and clinical success rates were 100% and 97%, respectively. Furthermore, the rate of occurrence of RBO and adverse events was 49% and 21%, respectively. The length of bile duct stenosis (<2.2 cm) was the only significant risk factor for stent migration. Conclusions: The non-obstruction rate of a novel fully covered SEMS for MDBO is comparable to that reported earlier but shorter than expected. Short bile duct stenosis is a significant risk factor for stent migration.

• Tuberculosis and Respiratory Diseases
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• 제58권3호
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• pp.295-298
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• 2005

전방경추융합술을 시행한 후 역설상기도폐쇄와 중추성 무호흡이 발생하였던 증례를 경험하여 이를 보고하고자 한다. 환자는 48세 남자로 본원으로 전원되기 9개월 전에 5번과 6번 경추사이의 추간판탈출증으로 수술을 시행받았으며, 내원 2개월 전에는 가성관절증이 발생하여 자가골이식과 함께 전방접근법으로 5번과 6번 경추의 경추융합술을 시행받았다. 이 수술을 시행 후 환자는 코골이와 과도한 주간 졸음증, 불면증 등의 증세가 생겼으며 호흡시에 상기도부위에서 이상한 소리가 발생하였다. 코인두경 및 자기공명영상으로 호기시 코인두부위의 역설적 협착소견을 관찰할 수 있었고, 철야 수면다원검사에서 무호흡지수는 8.7/시간 (중추성 무호흡, 7.0/시간; 폐쇄성 무호흡, 1.7/시간)이었다. 경비적 지속성 기도양압치료를 시작하였으나 환자가 압력을 못견뎌하여 레이저목젖입천장성형술을 시행하였다. 수술 2개월 경과 후 무호흡과 더불어 임상증세는 현격히 호전되었다. 저자들은 이러한 역설상기도폐쇄가 비록 그 기전이 명확하지는 않지만 전방경추융합술과 관련되어 있다고 추정한다. 또한 이러한 상기도 폐쇄가 중추성 수면 무호흡을 유발할 수 있다는 것을 보여주는 증례라고 생각한다.