• Title/Summary/Keyword: central function

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Development and Usability Test of the Prototype of the "Smart Stacking Cone" Based on Dual-task Using ICT (ICT를 이용한 이중과제 기반의 스마트 스태킹 콘의 시제품 개발 및 사용성 평가)

  • Lim, Seung-Ju;Won, Kyung-A;Kim, Dae-Gyeom;Kim, Young;Park, Ji-Hyuk
    • Therapeutic Science for Rehabilitation
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    • v.10 no.2
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    • pp.95-108
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    • 2021
  • Objective : This study aimed to develop prototypes of "smart stacking cones" by combining ICT to evaluate and train the upper extremity function and dual task performance in patients with central nervous system impairment, and to identify the complementary point to the completion of the device through a usability test. Methods : This prototype comprised of a hardware and software system that enabled the evaluation and training of patients and the management of data obtained from patients' performance. Specific measurement variables were established so that patient performance could be measured correctly. Based on the measurement variables, a the prototype included a 'single task evaluation modes', 'dual task evaluation mode', 'single task training mode', and 'dual task training modes'. Additionally, a usability test was conducted to assess clinical applicability and overall satisfaction for the prototype. Results : The results of the usability test were generally found to be appropriate. The 'content adequacy' in the usability test was the area with the highest level of adequacy and the lowest level of inadequacy. Additionally, overall 'satisfaction' in the usability test was the area with the highest appropriate and inappropriate levels. Hence, the overall satisfaction results were unstable. Conclusion : Future studies should be conducted to identify the clinical effectiveness of the device by applying an upgraded smart stacking cone to an actual patient group.

Analysis of Co-authorship Network in the Lifelong Vocational Education and Training: An Analysis of Papers Published from 2000 to 2015 in Korea (평생 직업교육훈련 분야의 공저자 네트워크 분석: 2000년~2015년 국내 학술논문을 중심으로)

  • Park, Ji-Young;Lee, Hee-Su
    • Journal of vocational education research
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    • v.35 no.6
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    • pp.85-112
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    • 2016
  • This study aims to identify the cooperative relations among researchers and their network structures based on the academic papers published in the field of lifelong vocational education and training from 2000 to 2015. Authors in three representative journals, 'Journal of Lifelong Education', 'Journal of Vocational Education Research', and 'Korea Research Institute for Vocational Education & Training,' during the periods, were selected and co-authorship network analysis was applied using NetMiner 4.0 in order to find the social relation among researchers and their academic influences. The results showed that the research productivity in the field of lifelong vocational education and training forms a shape of the power function where there exist components called, 'detailed research groups.' This network structure represents characteristics of a small world. In addition, the centrality analysis suggest authors with high centrality serve as co-authors who play as a central role on the network and exchange information with other researchers, while those with high betweenness centrality serve as a channel where they transfer knowledge and information among research groups. Increasing member of co-authorship has positively contributed to the opportunity and development of cooperative research among researchers in the field of lifelong vocational education and training. However it is recommended co-authorship be formed more heterogeneously instead of a few researches centrally dominate co-authorship. Various researchers should continually conduct research for good research performances.

Ngugi wa Thiong'o's Cultural Theory and Its Significance in Translation (응구기 와 시옹오의 문화이론과 번역의 의미)

  • Lee, Hyoseok
    • Cross-Cultural Studies
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    • v.46
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    • pp.411-434
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    • 2017
  • With emphasis on various local cultures to confront the Western central culture, Ngugi wa Thiong'o proposes them 'to move horizontally' so as not to repeat the oppressive culture of the West. We need not only dialogues between dominant languages and peripheral languages, but also between marginal languages. With respect to this point, Ngugi thinks that translation itself could be very effective. Ngugi wants to stimulate writing and speaking in marginalized languages and promote translation as a means of making these languages visible. He regards translation as a conversational tool among languages and cultures in the multicultural global community. As is already well known, his determination to write his later works only in his native Gikuyu language has a great meaning in his anti-colonial as well as anti-neocolonial movement. Its proof is his recent effort to cooperate with Jalada Africa. Simon Gikandi criticized the English translation of Matigari as a denial of cultural hegemony of Gikuyu language and its subordination to the global cultural market. However, the concept of 'thick translation', helps us move from Gikandi's doubt of the 'epistemology of translation' to a meaningful strategy of postcolonial translation. Facing some of the scholars' doubts related to his over-stressing language problem, Ngugi points out that the world has managed to function well through translation: the possibility of translation between cultures and translation as a mediating tool for communication nationally as well as internationally. Based on this two-sided solution of translation, he believes that we can overcome the opposition between relativity and universality, center and periphery, and the dominant and the subordinate.

Effects of combined exercise on the blood inflammatory factors, DHEA-s and arterial stiffness of elderly women (복합운동이 고령여성의 혈중 염증인자, DHEA-s 및 동맥경직도에 미치는 영향)

  • Ha, Soo-Min;Kim, Jung-Sook;Kim, Ji-Hyeon;Kim, Do-Yeon
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.4
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    • pp.1096-1107
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    • 2018
  • The purpose of this study was to investigate the effects of combined exercise on blood inflammatory factors, DHEA-s and arterial stiffness in elderly women. The subjects were 42 elderly females volunteers, aged 70 to 85 years, composed of the combined exercise group (n=21) and control group (n=21). The 60 minute combined exercise program(aquarobics 1 time/week, strength exercise 2 times/week) was performed 3 times per week for 12 weeks, and the intensity was progressively increased every 4 weeks(1-4 weeks: RPE 12 to 13, 5-8 weeks: RPE 13 to 14, 9-12weeks: RPE 14 to 15). The test data were analyzed by two-way repeated measures ANOVA, paired t-test, independent t-test and the alpha level of .05 was set for all tests of significance. As a result, the combined exercise for 12 weeks reduced the inflammatory response of elderly women, and DHEA-s was found to have a positive effect on aging hormone. The arterial stiffness decreased the central arterial blood pressure (systolic and diastolic), prevented the increase of the pulse pressure and the wave increase index, and decreased the pulse wave velocity. These results suggest that regular and continuous combined exercise may be recommended for the healthy aging and longevity of elderly women by inducing anti-inflammation effect and improving the aging hormonal function and the vascular health.

Numerical Study of the Heat Removal Performance for a Passive Containment Cooling System using MARS-KS with a New Empirical Correlation of Steam Condensation (새로운 응축열전달계수 상관식이 적용된 MARS-KS를 활용한 원자로건물 피동냉각계통 열제거 성능의 수치적 연구)

  • Jang, Yeong-Jun;Lee, Yeon-Gun;Kim, Sin;Lim, Sang-Gyu
    • Journal of Energy Engineering
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    • v.27 no.4
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    • pp.27-35
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    • 2018
  • The passive containment cooling system (PCCS) has been designed to remove the released decay heat during the accident by means of the condensation heat transfer phenomenon to guarantee the safety of the nuclear power plant. The heat removal performance of the PCCS is mainly governed by the condensation heat transfer of the steam-air mixture. In this study, the heat removal performance of the PCCS was evaluated by using the MARS-KS code with a new empirical correlation for steam condensation in the presence of a noncondensable gas. A new empirical correlation implemented into the MARS-KS code was developed as a function of parameters that affect the condensation heat transfer coefficient, such as the pressure, the wall subcooling, the noncondensable gas mass fraction and the aspect ratio of the condenser tube. The empirical correlation was applied to the MARS-KS code to replace the default Colburn-Hougen model. The various thermal-hydraulic parameters during the operation of the PCCS follonwing a large-break loss-of-coolant-accident were analyzed. The transient pressure behavior inside the containment from the MARS-KS with the empirical correlation was compared with calculated with the Colburn-Hougen model.

The Location and Range of Goryeo Palace in Gangwha (고려 강도궁궐의 위치와 범위 검토)

  • Lee, Sang-jun
    • Korean Journal of Heritage: History & Science
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    • v.47 no.3
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    • pp.108-127
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    • 2014
  • Gangwha was a capital city of Goryeo, in spite of short-term occupation, where various national facilities such as palace stood in a row. Nevertheless, its historic importance has been undervalued owing to undiscovered palace. According to ${\ll}Goryeosa{\gg}$, palace in Gangwha was built in imitation of that of Gaegyeong. If it is true, the site of the old palace in Gaeseong as an original could give significant information for that of Gangwha. The distinct feature of Gaegyeong is that the palace was located in the west area of the centerline from north to south and pond lay in the east side. There is a mountain in the center of capital and two rivers runs along side the mountain. Gunggol at Gwancheong-ri is a best place where structural peculiarities of Gaegyeong can be applicable to Gangwha. There is an area of celadon distribution and is some topographic similarities such as central mountain, two rivers are quite similar. It is assumable that excavation result of no. 405 Gwancheongri reflects the function of east pond and thoroughfare responds to main street from north to south of Gaegyeong. After all the analysis from archaeological information, old maps, cadastral maps, topographic similarities and so on, Gunggol at Gwancheong-ri within an arc shape road is a most suitable place as palace in Gangwha.

Evoked Potentials before the Intractable Epilepsy Surgery (난치성 뇌전증 환자에서 수술 전 유발전위검사)

  • Lim, Sung Hyuk;Park, Sang Ku;Baek, Jae Seung;Kim, Kab Kyu;Kim, Ki Eob;Lee, Yu Ji
    • Korean Journal of Clinical Laboratory Science
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    • v.51 no.2
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    • pp.198-204
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    • 2019
  • Various treatments can be attempted in patients with intractable epilepsy, in whom the symptoms of seizures are not controlled by various drugs. On the other hand, in patients requiring a surgical method, a preoperative examination is needed to determine the portion of seizure site to be resected. Electrodes are inserted into the cerebral cortex for accurate lesion measurements and safe operation. The electrodes inserted in the cortex not only record the electroencephalography (EEG), but also allow various tests to confirm the function of the part. One of these methods is the evoked potential test. From January 2015 to December 2018, the trends of measured waveforms in were analyzed 70 patients. The somatosensory evoked potential (SSEP) recorded on the electrode inserted in the cerebral cortex can be searched for the pathway of the central sulcus to avoid the primary motor area and primary sensory area. In addition, using the middle latency auditory evoked potentials (MLAEP) and flash visual evoked potentials (FVEP), the functional cortex in the auditory cortex and the visual cortex were compared with the seizure focus point on the EEG to help determine the location of the ablation and minimize functional impairment after surgery.

Localization of Bilateral Hemisphere Lesion Using Combined Transcranial Magnetic Stimulation and Diffusion Tensor Imaging: Report of Two Cases (경두개 자기자극과 확산텐서 신경섬유로 검사를 통한 대뇌 병변의 국소화: 증례보고)

  • Lee, Hyung Nam;Oh, Young-Bin;Kim, Gi-Wook;Won, Yu Hui;Ko, Myoung-Hwan;Seo, Jeong-Hwan;Park, Sung-Hee
    • Journal of Electrodiagnosis and Neuromuscular Diseases
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    • v.20 no.2
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    • pp.106-111
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    • 2018
  • Transcranial magnetic stimulation (TMS) has been a gold standard for investigating central motor pathways in humans. Diffusion tensor imaging with fiber tractography (DTI FT) is known for its usefulness in detecting white matter lesion in vivo. We investigated the clinical usefulness of elucidating the integrity and continuity of corticospinal tract (CST) by combined use of TMS and DTI FT in this study. We report two cases who have presented with left hemiparesis and evaluated by both TMS and DTI FT; 10-year-old boy with Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like episode syndrome and 20-year-old woman with traumatic brain injury. Combined use of TMS and DTI FT successfully led to localize the brain lesion that might cause motor impairment in patients with abnormal signal intensities in MRI. The results of this study suggest that TMS and DTI FT might provide the detailed information between function and anatomy of the CST, complementarily.

NLRP3 Inflammasome in Neuroinflammatory Disorders (NLRP3 인플라마좀 작용 기전 및 신경 질환에서의 역할)

  • Kim, Ji-Hee;Kim, YoungHee
    • Journal of Life Science
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    • v.31 no.2
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    • pp.237-247
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    • 2021
  • Immune responses in the central nervous system (CNS) function as the host's defense system against pathogens and usually help with repair and regeneration. However, chronic and exaggerated neuroinflammation is detrimental and may create neuronal damage in many cases. The NOD-, LRR-, and pyrin domain―containing 3 (NLRP3) inflammasome, a kind of NOD-like receptor, is a cytosolic multiprotein complex that consists of sensors (NLRP3), adaptors (apoptosis-associated speck like protein containing a caspase recruitment domain, ASC) and effectors (caspase 1). It can detect a broad range of microbial pathogens along with foreign and host-derived danger signals, resulting in the assembly and activation of the NLRP3 inflammasome. Upon activation, NLRP3 inflammasome leads to caspase 1-dependent secretion of the pro-inflammatory cytokines IL-1β and IL-18, as well as to gasdermin D-mediated pyroptotic cell death. NLRP3 inflammasome is highly expressed in CNS-resident cell types, including microglia and astrocytes, and growing evidence suggests that NLRP3 inflammasome is a crucial player in the pathophysiology of several neuroinflammatory and psychiatric diseases, such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, traumatic brain injury, amyotrophic lateral sclerosis, and major depressive disorder. Thus, this review describes the molecular mechanisms of NLRP3 inflammasome activation and its crucial roles in the pathogenesis of neurological disorders.

The Study of Statistical Optimization of 1,4-dioxane Treatment Using E-beam Process (전자빔 공정을 이용한 1,4-Dioxane 처리의 통계적 최적화 연구)

  • Hwang, Haeyoung;Chang, Soonwoong
    • Journal of the Korean GEO-environmental Society
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    • v.12 no.4
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    • pp.25-31
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    • 2011
  • In this study, the experimental design methodology was applied to optimize 1,4-dioxane treatment in E-beam process. Main factor was mathematically described as a function of parameters 1,4-dioxane removal efficiencies(%), TOC removal efficiencies(%) modeled by the use of the central composite design(CCD) method among the response surface methodology(RSM). Concentration of 1,4-dioxane is designated as "$x_1$" and Irradiation intensity is designated as "$x_2$". The regression equation in coded unit between the 1,4-dioxane concentration and removal efficiencies(%) was $y=71.00-10.85x_1+20.67x_2+{1.53x_1}^2-{7.92x_2}^2-1.23x_1x_2$. The regression equation in coded unit between the 1,4-dioxane concentration and TOC removal efficiencies(%) was $y=44.48-13.25x_1+9.54x_2+{5.43x_1}^2-{1.35x_2}^2+4.45x_1x_2$. The model predictions agreed well with the experimentally observed results $R^2$(Adj) over 90%. Toxicity test using algae Pseudokirchneriella Subcapitata showed that the inhibition was reduced according to increasing an E-beam irradiation.