• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권5호
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• pp.376-386
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• 2022

Functional gastrointestinal disorders (FGIDs) are classified as a combination of persistent gastrointestinal symptoms. The Rome IV criteria can elucidate several factors in the pathogenesis of FGIDs. The frequency of FGIDs can differ between clinical and nonclinical settings and between geographic regions. To determine the global prevalence of FGIDs in neonates and toddlers according to the Rome IV criteria. We included cohort and descriptive observational studies reporting the prevalence of FGIDs according to the Rome IV criteria in children aged 0-48 months. We searched the Medline, Embase, Lilacs, and CENTRAL databases from May 2016 to the present day. Furthermore, unpublished literature was searched to supplement this information. The Strengthening the Reporting of Observational Studies in Epidemiology statement was used to evaluate the risk of bias. A meta-analysis of the proportions was performed using MetaProp in R. The results are reported in forest plots. We identified and analyzed 15 studies comprising 48,325 participants. Six studies were conducted in Europe, three in Latin America, two in North America, and four in Asia. Most participants were 12-48 months old (61.0%) and were recruited from the community. The global prevalence of FGIDs was 22.0% (95% confidence interval, 15-31%). The most common disorder was functional constipation (9.0%), followed by infant regurgitation syndrome (8.0%). Its prevalence was higher in the Americas (28.0%). FGIDs, as defined by the Rome IV criteria, are present in 22% of children, and the most common primary disorder is functional constipation. A higher prevalence of FGIDs has been reported in America.

• Natural Product Sciences
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• 제28권4호
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• pp.168-180
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• 2022

Ephedra is a genus of the Ephedraceae family and is found in temperate regions, such as Central Asia and Europe. Among the various ephedra species, Ma Huang (Ephedra herb) is derived from the aerial parts of Ephedra sinica S tapf, Ephedra equisetina Bunge, and Ephedra intermedia Schrenk & C.A. Mey. Ma Huang contains various ephedra alkaloids, including (-)-ephedrine, (+)-pseudoephedrine, (-)-norephedrine, (+)-norpseudoephedrine, (-)-methylephedrine, and (+)-methylpseudoephedrine, which are found naturally as single enantiomers, although they can be prepared as racemates. Although the use of Ma Huang in foods is prohibited in Korea, products containing Ma Huang can be imported, and so it is necessary to develop a suitable analytical technique for the detection of Ma Huang in foods. Herein, we report the development of analytical methods for the detection of ephedra alkaloids in products containing Ma Huang. Following sample purification by solid phase extraction, quantitative analysis was performed using ultra-performance liquid chromatography-triple quadrupole mass spectrometry (UPLC-MS/MS). Additionally, the enantiomers were successfully separated using HPLC-DAD. We successfully analyzed various food samples, where the ephedra alkaloids were qualitatively and quantitatively determined, and the enantiomers were separated. It is expected that these methods may contribute toward preventing the distribution of illegal products containing Ma Huang.

• 대순사상과 동아시아종교
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• 제2권2호
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• pp.101-121
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• 2023

Daoism was introduced into the South-West of Vietnam via two main entries: the missionaries from North and Central Vietnam who migrated to the South by following the Southward movement and the spread of Daoism by Chinese migrant men who came and settled in the South-West of Vietnam from the late seventieth century to late nineteenth century. However, the biggest influence of Daoism in the Southwest of Vietnam was mainly the Chinese missionaries of Daoism. As time went by, together with the impacts of social and historical circumstances, Daoism had a strong influence on the lives of the South-West people in terms of different aspects, especially their faith and religions. The impact of Daoism into people's faith and religion was considerable, especially to the indigenous religions, of which the religion, Four Debts of Gratitude, is a representative example. With the aims of clarifying how Four Debts of Gratitude was influenced by Daoist thought and how the indigenous religions and systemized ideologies in the South-West of Vietnam were related during the period of living condition expansion as well as cohabitation of several ethnic groups in the region, this article focuses on Daoist thought expressed in typical symbols in the sacred architecture of the Four Debts of Gratitude such as Cổ Lầu, wine gourds, and the Eight Trigrams. Once properly examined, it becomes clear that the prominent symbols and other Daoist elements show that Daoism had a profound influence on the Four Debts of Gratitude.

• 예술인문사회 융합 멀티미디어 논문지
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• 제7권3호
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• pp.301-310
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• 2017

양자점 셀룰라 오토마타(QCA: quantum-dot cellular automata)는 나노 크기의 셀을 이용하여 다양한 연산을 수행하며, 매우 빠른 연산속도와 적은 전력손실로 차세대 기술로 떠오르고 있다. 본 논문에서는 QCA 상에서 새로운 유니버셜 게이트(universal gate)를 제안한다. 또한, 유니버셜 게이트를 이용하여 시공간 효율성 측면에서 우수한 XOR 게이트를 제안한다. 유니버셜 게이트는 자기 자신으로 모든 기본 논리 게이트를 만들어 낼 수 있는 게이트이다. 한편, 제안된 유니버셜 게이트는 기본 셀과 회전된 셀을 활용하여 설계한다. 제안된 유니버셜 게이트의 회전된 셀은 3-입력 다수결게이트 구조의 중앙부에 위치한다. 3-입력 다수결 게이트를 이용하여 XOR 게이트를 설계할 때는 5개 이상의 3-입력 다수결 게이트가 사용되지만, 본 논문에서는 3개의 유니버셜 게이트를 사용하여 XOR 게이트를 제안한다. 제안하는 XOR 게이트는 기존의 XOR 게이트보다 사용된 게이트 수가 줄었으며 설계 면적이나 소요 클럭면에서 우수함을 확인할 수 있다.

• 대한한방내과학회지
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• 제44권3호
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• pp.285-293
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• 2023

Background: Irritable bowel syndrome (IBS) is a digestive disorder characterized by abdominal discomfort or pain accompanied by a change in stool condition. Owing to its complicated mechanisms, a standard treatment for IBS has not yet been established. Yukgunja-tang (YGT) is a Korean herbal medicine known in Asia to be effective in the treatment of gastrointestinal symptoms. In this study, we will conduct a systematic review of randomized controlled trials (RCTs) to assess the efficacy and safety of YGT in IBS treatment. Methods and analysis: English databases, such as Embase, Medline (via PubMed), Allied and Complementary Medicine Database, and Cochrane Central Register of Controlled Trials, will be searched for articles published up to April 2023. Additional databases, such as five Korean, one Chinese, and one Japanese database, will be included. RCTs and quasi-RCTs will also be included in the assessment of the efficacy of YGT. The overall efficacy rate will be the primary outcome, and data such as IBS quality-of-life measurements, global symptom scores, and adverse events will be the secondary outcomes. Review Manager Version 5.3 will be used for evaluation, and the risk of bias (RoB) will be evaluated using Cochrane Collaboration's RoB tool. The Grading of Recommendations Assessment, Development, and Evaluation approach will be used to score the quality of evidence. Conclusion: This study will demonstrate the efficacy and safety of YGT for treating patients with IBS.

• 한국비블리아학회지
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• 제20권3호
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• pp.149-161
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• 2009

본 연구의 목적은 "한국십진분류법(KDC) 제5판"이 발간됨에 따라 역사(900) 분야에 대한 개정된 내용을 조사 분석하여, "한국십진분류법(KDC) 제6판"의 개정 방향을 제시하는데 있다. 주요 분석 내용은 크게 네 가지로 구분할 수 있다. 첫째, 지역구분에 대한 부분으로 지역구분표의 확장, 지역구분에서 계층구조의 강조, 북한 지역을 행정구역 명칭으로 변경, 외국의 주요 국가에 대해서 세부적인 지역구분, 중앙 및 서남 아시아 국가들의 위치 조정 등이 포함되었다. 둘째, 대한민국의 시대구분을 확장하였다. 셋째, 중국과 일본의 항목 주기를 간소화하였다. 넷째, 용어의 조정으로 중국 및 일본의 지명과 인명을 자국발음으로 변경하였고, 외국 지명에 대해 한국어로 번역하는 것을 지양하고 원음 그대로 적용하였다. 6판의 개정방향으로 한국지역구분에서 계층구조를 적용한 광역단위 전개, 해당 국가의 수도를 중심으로 한 지역전개, 자국에서 사용하는 지명표기, 시대별 연도구분을 제시하였다.

• 한국경제지리학회지
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• 제26권3호
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• pp.256-273
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• 2023

본 연구는 2009년부터 2021년까지 IMF의 CDIS(Coordinated Direct Investment Survey) 자료를 이용하고 사회 네트워크 분석 방법을 활용하여 글로벌 해외직접투자 네트워크의 변화를 분석하였다. 주요 분석 결과는 다음과 같다. 첫째, 코로나19 팬데믹 이후 국가 간 FDI 관계의 긴밀성이 약화되고, 상호 관계 활동성이 축소되었다. 둘째, 글로벌 해외직접투자 네트워크에서 가장 영향력이 있는 국가는 미국, 네덜란드, 영국 등인 것으로 나타났다. 셋째, 불안정한 글로벌 경제 환경 속에서 중국의 연결 중심성이 크게 변화하였다. 넷째, 해외직접투자 네트워크의 클러스터와 지역 간에는 유의미하게 연관성이 있는 것으로 나타났으며, 긴밀하게 연결되어 있는 개별 국가들의 투자 파트너들은 시간의 흐름에 따라 차별적인 특징을 보인다.

• 한국지반공학회논문집
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• 제40권3호
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• pp.19-31
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• 2024

국내 항타 말뚝기초의 경우 대부분 풍화암 이상의 단단한 지층에 선단 지지되는 경우가 대부분이며, 서남해 지역의 연약지반이 깊게 발달한 일부에서 마찰 말뚝(friction pile)이 사용되었으나 시공관리의 불확실성으로 제한적으로 적용되고 그 사례가 많지 않다. 또한 시공과 관련하여 국내의 경우 소음 및 진동 등의 민원문제로 매입 시공이 주를 이루고 있으나, 퇴적지반이 깊은 동남아 국가(캄보디아, 미얀마, 베트남 등) 등에서는 경제성 확보를 위해 항타 시공을 통한 말뚝 시공 비율이 높으며, 그에 따른 시공 및 현장관리 경험이 많이 축적되어 있다. 현재 국내 많은 건설 기업들이 동남아 등 해외 시장 진출 사례가 크게 증가함에 따라, 해당국가에서의 경쟁력 확보를 위해서는 항타시공을 이용한 마찰지지 말뚝 시공사례에 따른 문제점들을 파악하고 현장관리 역량을 강화해야 할 필요가 있다. 이에 본 연구에서는 베트남 중부 연안의 대심도 점토지반에 항타 시공된 마찰지지 강관 말뚝의 동적/정적 재하시험 결과의 비교분석과 이를 토대로 수정된 항타공식을 이용한 강관 말뚝의 시공관리 방안을 제안하였다.

• 아태비즈니스연구
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• 제15권1호
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• pp.209-223
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• 2024

Purpose - This article analyzes the impact of macroeconomic variables of the United States, China, and Korea on KOSPI and VKOSPI, in that United States and China have a great influence on Korea, having an export-driven economy. Design/methodology/approach - The influence of US, China, and Korea interest rates, industrial production index, consumer price index, US employment index, Chinese real estate index, and Korea's foreign exchange reserves on KOSPI and VKOSPI is analyzed on monthly basis from Jan 2012 to Aug 2023, using multifactor model. Findings - The KOSPI showed a positive relationship with the U.S. industrial production index and Korea's foreign exchange reserves, and a negative relationship with the U.S. employment index and Chinese real estate index. The VKOSPI showed a positive relationship with the Chinese consumer price index, and a negative relationship with the U.S. interest rates, and Korean foreign exchange reserves. Next, dividing the analysis into two periods with the Covid crisis and the analysis by country, the impact of US macroeconomic variables on KOSPI was greater than Chinese ones and the impact of Chinese macroeconomic variables on VKOSPI was greater than US ones. The result of the forward predictive failure test confirmed that it was appropriate to divide the period into two periods with economic event, the Covid Crisis. After the Covid crisis, the impact of macroeconomic variables on KOSPI and VKOSPI increased. This reflects the financial market co-movements due to governments' policy coordination and central bank liquidity supply to overcome the crisis in the pandemic situation. Research implications or Originality - This study is meaningful in that it analyzed the effects of macroeconomic variables on KOSPI and VKOSPI simultaneously. In addition, the leverage effect can also be confirmed through the relationship between macroeconomic variables and KOSPI and VKOSPI. This article examined the fundamental changes in the Korean and global financial markets following the shock of Corona by applying this research model before and after Covid crisis.

• Journal of Contemporary Eastern Asia
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• 제23권1호
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• pp.18-34
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• 2024

In what was labeled the "nut rage" incident, the vice president of Korean Air, Hyun-Ah Cho (Heather Cho), demonstrated behavior that exemplifies corporate transgression and deviation from societal moral standards toward a flight attendant aboard a flight. Such behavior instigated the public to express negative sentiment on various social media platforms. This study investigates word-of-mouth network on YouTube in response to the crisis, patterns of co-commenting activities across selected YouTube videos, as well as public responses to the incident by employing social and semantic network analysis. A total of 512 YouTube videos featuring the crisis from December 8, 2014 through November 11, 2018, and 52,772 public comments to the videos were collected. The central videos in the network successfully attracted the public's attention and engagements. The results suggest that the video network was decentralized, with multiple videos acting as hubs in the network. The public commented on various videos instead of focusing on a few. The contents of influential videos uploaded by popular news organizations revealed not only Cho's behaviors related to the nut rage crisis but also unrelated illegal behaviors and the moral violations committed by the family members of Korean Air. The public attached derogatory remarks to Cho and her family, and the comments also addressed ethical concerns, management issues of the company, and boycott intentions. The results imply that adverse public reaction was related to the long-standing problem caused by family ownership and governance in large Korean corporations. This Korean Air scandal illustrates backlash toward a leadership breakdown by the family business conglomerate prevalent in the Korean society. This study provides insights for effective handling of similar crises.