• Title/Summary/Keyword: center selection

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Production of Lipocortin-1$_{1-185}$ Using A Recombinant of Escherichia coli.

  • Lee, Kyung-Il;Oh, Kyung-Hee;Lee, Jung-Hyun;Na, Do-Sun;Lee, Kye-Joon
    • Journal of Microbiology
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    • v.35 no.2
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    • pp.123-126
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    • 1997
  • The aim of the present study was to optimize culture condition for the expression of lipocortin-1$_{1-185}$ in a recombinant of Escherichia coli using batch system. Plasmid (pHT22) carrying lipocortin-1$_{1-185}$ gene was well maintained in the recombinant with the addition of amplicillin as a selection pressures. Optimum temperature was 28$^{\circ}C$ for seed culture and 4$0^{\circ}C$ for main culture and the optimum pH was 7.0. The production of Lipocortin-1$_{1-185}$ was closely associated with cell growth and related to plasmid amplification.

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Loss of gene function and evolution of human phenotypes

  • Oh, Hye Ji;Choi, Dongjin;Goh, Chul Jun;Hahn, Yoonsoo
    • BMB Reports
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    • v.48 no.7
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    • pp.373-379
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    • 2015
  • Humans have acquired many distinct evolutionary traits after the human-chimpanzee divergence. These phenotypes have resulted from genetic changes that occurred in the human genome and were retained by natural selection. Comparative primate genome analyses reveal that loss-of-function mutations are common in the human genome. Some of these gene inactivation events were revealed to be associated with the emergence of advantageous phenotypes and were therefore positively selected and fixed in modern humans (the "less-ismore" hypothesis). Representative cases of human gene inactivation and their functional implications are presented in this review. Functional studies of additional inactive genes will provide insight into the molecular mechanisms underlying acquisition of various human-specific traits. [BMB Reports 2015; 48(7): 373-379]

Experimental Study on Air Arcs Interruption Phenomena with Arc Quenching Materials (소호 재료에 따른 기중 아크 차단 현상의 실험적 연구)

  • Lee, S.Y.;Yeon, Y.M.;Park, H.T.;Oh, I.S.
    • Proceedings of the KIEE Conference
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    • 2002.07c
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    • pp.1751-1753
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    • 2002
  • Arc phenomena occur in the air, must be more diverse than vacuum and SF6. An air arc interruption method has been used in low rated voltage circuit breakers such as ACB, MCCB and MCB. Most of them have the arc chamber composed of arc chutes and lateral walls that made of many kinds of materials. Therefore, the criterion of material selection is necessary for breaking capacity improvement. So, we selected some contact and lateral wall materials, and carried out short circuit tests. Especially, some parameters of arc plasma properties were very different each polymeric wall material.

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Development of a Spatial Location-Allocation Model of Center Villages(II) - Evaluating Applicability of Model for a Case Study Area - (농촌 중심마을의 공간적 입지-배분 모형의 개발(II) - 모형의 적용 및 응용성 평가 -)

  • 김대식;정하우
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.43 no.3
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    • pp.46-55
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    • 2001
  • Following the previous paper on development of the spatial location-allocation model of center villages (SLAMCV), this paper, the 2nd stage of the this study, aims to check up its applicability for several planning scenarios by the case study. Among 72 natural villages of Ucheon-myeon, Gangwon-do, Korea the highest single center was simulated as Uhang village and the higher double centers as Uhang and Jeonggeum villages, which coincided exactly with the existing centers. The SLAMCV was well operated for three planning scenarios such as selection of the 3rd center village and its hinter villages for Ucheon-myeon, Gargwon-do, Korea by dividing three living spheres, impact assessment evaluation of road improvement projects on the spatial accessibility, and analysis of centerality changes of settlement units by new road construction.

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A Case Study of Six Sigma Project for Improving Productivity of the Brace Complement Center Pillar (Brace Complement Center Pillar의 생산성 향상을 위한 6시그마 프로젝트사례)

  • Lee, Min-Koo;Lee, Kwang-Ho
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.29 no.1
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    • pp.9-17
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    • 2006
  • This paper considers a six sigma project for improving productivity of the brace complement center pillar. The project follows a disciplined process of fife phases: define, measure, analyze, improve, and control. A process map is used to identify process input and output variables. Eleven key process input variables are selected by using X&Y matrix and FMEA, and finally eight vital few input variables are selected from analyze phase. The optimum process conditions of the vital few input variables are jointly obtained by maximizing productivity of the brace complement center pillar using DOE and alternative selection method.

The Long-Term Safety and Efficacy of Intrathecal Therapy Using Sufentanil in Chronic Intractable Non-Malignant Pain

  • Monsivais, Jose Jesus;Monsivais, Diane Burn
    • The Korean Journal of Pain
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    • v.27 no.3
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    • pp.297-300
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    • 2014
  • This report describes the long term safety and efficacy of intrathecal therapy using Sufentanil for the management of chronic intractable neuropathic pain in 12 chronic pain patients. Standardized psychological screening was used to determine treatment suitability. Evaluation data included the Visual Analog Scale (VAS), Wong-Baker Faces Scale, Brief Pain Inventory (BPI), Disability of Arm, Shoulder, and Hand (DASH), McGill Quality of Life Questionnaire, and complications (granulomas, toxicity, withdrawal, or deaths). SPSS version 18 was used for data analysis. Pre- and post- treatment BPI measures and pain scale scores showed a statistically significant difference. There were no complications directly related to drug toxicity, nor drug withdrawals, granulomas, or deaths. Intrathecal therapy with Sufentanil therapy offers a good treatment alternative for those cases that have failed both surgery and standard pain treatment. Strict patient selection based on psychological screening, control of co-morbidities, a proper pain management may contribute to successful outcome.

Conservative Treatment of the Knee Injury and Pain (슬관절 손상과 동통의 보존적 치료)

  • Bin Seoung-I1;Nam Tae-Seok;Ahn Ji-Hyun;Jung Kwang-Whan
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.3 no.2
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    • pp.107-110
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    • 2004
  • Treatment of knee injury and pain consists of conservative and surgical treatment. Although conservative treatment is suffice in many cases, surgical treatment is performed which is not necessary. Therefore, thorough knowledge of injury mechanism and selection of treatment modalities are required. Injury mechanism and conservative treatment of knee injury patients will be discussed.

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Chinese Tourist Shopping Satisfaction and Brand Attitude to Korean Cosmetics : A Disconfirmation Approach

  • Yoon, Ju-Hee;Hwang, Yong-Cheol;Suh, Jaebeom;Kim, Jae-Gyun
    • Journal of Distribution Science
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    • v.15 no.10
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    • pp.51-63
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    • 2017
  • Purpose - The current study examines the shopping behavior of Chinese tourists who purchase Korean cosmetics when visiting Korea, based on expectancy-disconfirmation of shopping satisfaction and brand attitude toward Korean cosmetics. A moderating effect of consumer conformity on the relationships between cosmetics selection factors and two dimensions of disconfirmation - expectation and performance is also examined. Research design, data, and methodology - We conducted a survey with 250 Chinese tourists who visited Jeju, Korea and had purchased Korean cosmetics during their stay. Excluding 43 respondents' inputs because of incomplete answers and missing values, 207 responses were used in the final analysis. All hypotheses were tested using structural equation model (SEM). Results - We found that the Chinese tourist expectations had positive impact on their satisfaction, and the factors for cosmetic selection had a positive effect on shopping satisfaction and brand attitude. A moderating effect of consumer conformity was found to be significant. Conclusions - Given the significantly increased demand for Korean cosmetics from Chinese tourists, Korean cosmetics firms need to better understand cosmetics selection attributes and preference of Chinese tourists, which can provide a guideline to develop retail stores and distribution outlets for Chinese tourists.

Novel SINR-Based User Selection for an MU-MIMO System with Limited Feedback

  • Kum, Donghyun;Kang, Daegeun;Choi, Seungwon
    • ETRI Journal
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    • v.36 no.1
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    • pp.62-68
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    • 2014
  • This paper presents a novel user selection method based on the signal-to-interference-plus-noise ratio (SINR), which is approximated using limited feedback data at the base stations (BSs) of multiple user multiple-input multiple-output (MU-MIMO) systems. In the proposed system, the codebook vector index, the quantization error obtained from the correlation between the measured channel and the codebook vector, and the measured value of the largest singular value are fed back from each user to the BS. The proposed method not only generates precoding vectors that are orthogonal to the precoding vectors of the previously selected users and are highly correlated with the codebook vector of each user but also adopts the quantization error in approximating the SINR, which eventually provides a significantly more accurate SINR than the conventional SINR-based user selection techniques. Computer simulations show that the proposed method enhances the sum rate of the conventional SINR-based methods by at least 2.4 (2.62) bps/Hz when the number of transmit antennas and number of receive antennas per user terminal is 4 and 1(2), respectively, with 100 candidate users and an SNR of 30 dB.

The Effect of Segment Size on Quality Selection in DQN-based Video Streaming Services (DQN 기반 비디오 스트리밍 서비스에서 세그먼트 크기가 품질 선택에 미치는 영향)

  • Kim, ISeul;Lim, Kyungshik
    • Journal of Korea Multimedia Society
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    • v.21 no.10
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    • pp.1182-1194
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    • 2018
  • The Dynamic Adaptive Streaming over HTTP(DASH) is envisioned to evolve to meet an increasing demand on providing seamless video streaming services in the near future. The DASH performance heavily depends on the client's adaptive quality selection algorithm that is not included in the standard. The existing conventional algorithms are basically based on a procedural algorithm that is not easy to capture and reflect all variations of dynamic network and traffic conditions in a variety of network environments. To solve this problem, this paper proposes a novel quality selection mechanism based on the Deep Q-Network(DQN) model, the DQN-based DASH Adaptive Bitrate(ABR) mechanism. The proposed mechanism adopts a new reward calculation method based on five major performance metrics to reflect the current conditions of networks and devices in real time. In addition, the size of the consecutive video segment to be downloaded is also considered as a major learning metric to reflect a variety of video encodings. Experimental results show that the proposed mechanism quickly selects a suitable video quality even in high error rate environments, significantly reducing frequency of quality changes compared to the existing algorithm and simultaneously improving average video quality during video playback.