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Estimation of Formability for Sheet Metal Forming of Electronic Parts (전자 박판 부품의 가공성 평가에 대한 연구)

  • Lee, B.C.;Kang, S.Y.;Moon, J.H.
    • Journal of the Korean Society for Precision Engineering
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    • v.13 no.5
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    • pp.104-114
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    • 1996
  • For the improvement of productivity, the reduction of cost and time for manufacturing is mandatory, especially in the field of electromic industry. The study is concerned with a practical means of systematic assistance to formability estimation and selection of reliable design specification for electronic sheet metal parts. The objective of this research work is to develop a simulation system which hops to analyze the target processes with the finite element method and to acquire available design data quickly and exactly. The simulation system developed in the study consists of design verification, selection of optimal combination of parameters, knowledge acquisition and graphical user interface(GUI). Design verification is automatically carried out by using the finite element method. A data base management system and nomograms are utilized for knowledge acquisition. The developed system has been applied to some major sheet metal forming operations such as flanging, embossing, bending and blanking. According to the simulated results, the validation of the target processes has been confirmend. Analysis data, estimation rules of formability and graphical representation of the analysis have been employed for the designer's understanding and evaluation, thus providing a practical means of robust design and evaluation of forma- bility for producing electronic sheet metal parts.

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Expression of Dengue virus EIII domain-coding gene in maize as an edible vaccine candidate

  • Kim, Hyun A;Kwon, Suk Yoon;Yang, Moon Sik;Choi, Pil Son
    • Journal of Plant Biotechnology
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    • v.41 no.1
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    • pp.50-55
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    • 2014
  • Plant-based vaccines possess some advantages over other types of vaccine biotechnology such as safety, low cost of mass vaccination programs, and wider use of vaccines for medicine. This study was undertaken to develop the transgenic maize as edible vaccine candidates for humans. The immature embryos of HiII genotype were inoculated with A. tumefaciens strain C58C1 containing the binary vectors (V662 or V663). The vectors carrying nptII gene as selection marker and scEDIII (V662) or wCTB-scEDIII (V663) target gene, which code EIII proteins inhibite viral adsorption by cells. In total, 721 maize immature embryos were transformed and twenty-two putative transgenic plants were regenerated after 12 weeks selection regime. Of them, two- and six-plants were proved to be integrated with scEDIII and wCTB-scEDIII genes, respectively, by Southern blot analysis. However, only one plant (V662-29-3864) can express the gene of interest confirmed by Northern blot analysis. These results demonstrated that this plant could be used as a candidated source of the vaccine production.

Predicting Potential Epidemics of Rice Leaf Blast Disease Using Climate Scenarios from the Best Global Climate Model Selected for Individual Agro-Climatic Zones in Korea (국내 농업기후지대 별 최적기후모형 선정을 통한 미래 벼 도열병 발생 위험도 예측)

  • Lee, Seongkyu;Kim, Kwang-Hyung
    • Journal of Climate Change Research
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    • v.9 no.2
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    • pp.133-142
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    • 2018
  • Climate change will affect not only the crop productivity but also the pattern of rice disease epidemics in Korea. Impact assessments for the climate change are conducted using various climate change scenarios from many global climate models (GCM), such as a scenario from a best GCM or scenarios from multiple GCMs, or a combination of both. Here, we evaluated the feasibility of using a climate change scenario from the best GCM for the impact assessment on the potential epidemics of a rice leaf blast disease in Korea, in comparison to a multi?model ensemble (MME) scenario from multiple GCMs. For this, this study involves analyses of disease simulation using an epidemiological model, EPIRICE?LB, which was validated for Korean rice paddy fields. We then assessed likely changes in disease epidemics using the best GCM selected for individual agro?climatic zones and MME scenarios constructed by running 11 GCMs. As a result, the simulated incidence of leaf blast epidemics gradually decreased over the future periods both from the best GCM and MME. The results from this study emphasized that the best GCM selection approach resulted in comparable performance to the MME approach for the climate change impact assessment on rice leaf blast epidemic in Korea.

Outcomes of Gastrectomy for Gastric Cancer in Patients Aged >80 Years: A Systematic Literature Review and Meta-Analysis

  • Zelalem Chimdesa Merga ;Ji Sung Lee ;Chung-Sik Gong
    • Journal of Gastric Cancer
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    • v.23 no.3
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    • pp.428-450
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    • 2023
  • This meta-analysis examined the surgical management of older patients (>80 years) with gastric cancer, who were often excluded from randomized controlled trials. We analyzed 23 retrospective cohort studies involving 18,372 patients and found that older patients had a higher in-hospital mortality rate (relative risk [RR], 3.23; 95% confidence interval [CI], 1.46-7.17; P<0.01) and more post-operative complications (RR, 1.36; 95% CI, 1.19-1.56; P<0.01) than did younger patients. However, the surgical complications were similar between the two groups. Older patients were more likely to undergo less extensive lymph node dissection and longer hospital stays. Although older patients had statistically significant post-operative medical complications, they were not deprived of surgery for gastric cancer. The comorbidities and potential risks of post-operative complications should be carefully evaluated in older patients, highlighting the importance of careful patient selection. Overall, this meta-analysis provides recommendations for the surgical management of older patients with gastric cancer. Careful patient selection and evaluation of comorbidities should be performed to minimize the risk of post-operative complications in older patients, while recognizing that they should not be deprived of surgery for gastric cancer.

The Therapeutic Effect of Mindfulness-Based Interventions on Depressive Symptoms in Patients With Major Depressive Disorder: A Meta-Analysis (주요우울장애 환자의 우울증상에 대한 마음챙김 기반의 치료적 개입의 효과에 관한 메타분석)

  • Hannui Park;Seyeon Hong;Euihyeon Na;Myoung-Nam Lim;Kanguk Lee
    • Korean Journal of Biological Psychiatry
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    • v.31 no.1
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    • pp.7-14
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    • 2024
  • Objectives We conducted a meta-analysis of randomized controlled trials to investigate the therapeutic effects of mindfulness-based interventions on depressive symptoms in patients with major depressive disorder. Methods In February 2021, we searched Embase, MEDLINE, Cochrane Library, PsycINFO, CINAHL, and AMED. Under the guidance of the corresponding author, two evaluators independently reviewed and selected articles based on predetermined selection criteria. Results Based on the selection criteria, we systematically screened and included a total of 12 randomized controlled trials comprising 720 cases for the final analysis. Utilizing a random-effects model for data analysis, we determined the Hedges' g value to be 0.787, indicating a medium-sized effect according to Cohen's interpretation. The 95% confidence interval for the effect size ranged from 0.414 to 1.160 (p-value < 0.0001). Conclusions This study reveals the potential effectiveness of mindfulness-based interventions in treating depressive symptoms among patients with major depressive disorder.

Genetic signature of strong recent positive selection at interleukin-32 gene in goat

  • Asif, Akhtar Rasool;Qadri, Sumayyah;Ijaz, Nabeel;Javed, Ruheena;Ansari, Abdur Rahman;Awais, Muhammd;Younus, Muhammad;Riaz, Hasan;Du, Xiaoyong
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.7
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    • pp.912-919
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    • 2017
  • Objective: Identification of the candidate genes that play key roles in phenotypic variations can provide new information about evolution and positive selection. Interleukin (IL)-32 is involved in many biological processes, however, its role for the immune response against various diseases in mammals is poorly understood. Therefore, the current investigation was performed for the better understanding of the molecular evolution and the positive selection of single nucleotide polymorphisms in IL-32 gene. Methods: By using fixation index ($F_{ST}$) based method, IL-32 (9375) gene was found to be outlier and under significant positive selection with the provisional combined allocation of mean heterozygosity and $F_{ST}$. Using nucleotide sequences of 11 mammalian species from National Center for Biotechnology Information database, the evolutionary selection of IL-32 gene was determined using Maximum likelihood model method, through four models (M1a, M2a, M7, and M8) in Codeml program of phylogenetic analysis by maximum liklihood. Results: IL-32 is detected under positive selection using the $F_{ST}$ simulations method. The phylogenetic tree revealed that goat IL-32 was in close resemblance with sheep IL-32. The coding nucleotide sequences were compared among 11 species and it was found that the goat IL-32 gene shared identity with sheep (96.54%), bison (91.97%), camel (58.39%), cat (56.59%), buffalo (56.50%), human (56.13%), dog (50.97%), horse (54.04%), and rabbit (53.41%) respectively. Conclusion: This study provides evidence for IL-32 gene as under significant positive selection in goat.

Comparison of Offshore Wind Retrieval Software from SAR Satellite Imagery (SAR 위성영상 해상풍 추출 소프트웨어 비교)

  • Kim, Hyun-Goo;Hwang, Hyo-Jung;Kang, Yong-Heack;Yun, Chang-Yeol
    • New & Renewable Energy
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    • v.9 no.3
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    • pp.14-19
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    • 2013
  • Comparative evaluation of offshore wind retreival software, which use the satellite images taken by Synthetic Aperture Radar sensor; SARTools of CLS-SOPRONO, France and SpaceEye of London Research and Development Corporation, Canada is carried out. For a reference satellite image, ENVISAT ASAR imagery of Jeollanam-do Wan-do area when the winter-time northwestern wind prevails is processed by CMOD_IFR2, CMOD4, CMOD5 algorithms. Wind speed difference and its relative ratio are calculated to evaluate uncertainty of software selection.

Calibration and Uncertainty Analysis of Sample-Time Error on High Jitter of Samplers

  • Cho, Chihyun;Lee, Joo-Gwang;Kang, Tae-Weon;Kang, No-Weon
    • Journal of electromagnetic engineering and science
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    • v.18 no.3
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    • pp.169-174
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    • 2018
  • In this paper, we propose an estimation method using multiple in-phase and quadrature (IQ) signals of different frequencies to evaluate the sample-time errors in the sampling oscilloscope. The estimator is implemented by ODRPACK, and a novel iteration scheme is applied to achieve fast convergence without any prior information. Monte-Carlo simulation is conducted to confirm the proposed method. It clearly shows that the multiple IQ approach achieves more accurate results compared to the conventional method. Finally, the criteria for the frequency selection and the signal capture time are investigated.

A Study on the Middle Age Women's Needs of Educare Services (중년 여성의 보육서비스에 대한 요구도)

  • Ahn, Ji-Yun
    • Korean Journal of Human Ecology
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    • v.6 no.2
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    • pp.1-14
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    • 1997
  • The purpose of this study was to find out middle age women's needs of the educare services. Furthermore this study was done to serve as the basic data for guidance and the preparation of effective educare services. For these purposes, the data were collected by using questionnare from to 305 middle age women living in T city. The data were analyzed by frequency, percentile, chi square analysis. The major findings of this research are as follows: 1. Most subjects of present study needs for the daycare center. Furthermore there were significant differences in the daycare management, caring agent, day care cost according to the school career. 2. They wantd nere home daycare center and part time daycare center. And there were no significant differences in general enviroment of daycare center according to the school career. 3. There were significant differences in 1)the standards of selection for teacher 2)teacher's educational level, 3)teacher's age according to the school level. And they wanted 'low school career but caring experiences' daycare teacher.

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