• Journal of Applied Biological Chemistry
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• v.48 no.4
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• pp.207-212
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• 2005

Prolyl endopeptidase (PEP, EC 3.4.21.26), also referred to as prolyl oligopeptidase, has been suggested to participate in learning and memory processes by cleaving peptide bonds on carboxyl side of prolyl residue within neuropeptides of less than 30 amino acids, and is abundant in brains of amnestic patients. Therefore, compounds possessing PEP inhibitory activity can be good candidate of drug against memory loss. Upon examination for PEP inhibition from traditional medicinal plants having tonic, stimulating, and anti-amnestic effects, Corni Fructus (Cornus officinallis) showed significant PEP inhibition. Ursolic and oleanolic acids, components of Corni Fructus, inhibited PEP with $IC_{50}$ values of $17.2\;{\pm}\;0.5$ and $22.5\;{\pm}\;0.7\;{\mu}M$, respectively.

• Journal of Microbiology and Biotechnology
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• v.2 no.2
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• pp.129-134
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• 1992

Segregational instability of a recombinant plasmid, pDML6, encoding extracellular $\beta$-lactamase in Streptomyces lividans PD6 was characterized by growth kinetic analysis. The quantitative determination of the plasmid harbored in the mycelia was evaluated with mycelia fragmented mechanically, and also with colonies regenerated from protoplasts. Conditions for the formation of protoplasts and regeneration of protoplasts were established. The maximal specific growth rates of the host strain and the plasmid-harboring strain in a chemically defined medium without selection pressure were the same. The probability of plasmid loss from the harbouring cells was higher at higher growth rates. Mathematical models for the prediction of cell growth, substrate uptake, and accumulation of the cloned gene product were developed.

• Proceedings of the KIEE Conference
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• 2005.07a
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• pp.483-485
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• 2005

In 2003, there was a wide-area blackout in the United States and Canada. More than fifty million people underwent power failure and the estimated financial loss was about four billion dollars. By such wide-area blackouts, the interest in voltage stability has increased gradually. In order to maintain the voltage stability, the preventive control is essential for a contingency. In this paper, a proper preventive control is determined for defined severe contingencies. Among the preventive control methods (generation rescheduling, load curtailment, tap adjusting, injecting the shunt capacitor, and so on.), this paper presents the injection of shunt capacitors by the sensitivity analysis of the voltage stability assessment for preventive controls. The 2006-2010 KEPCO summer peak system is used in case studies.

• Genomics & Informatics
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• v.11 no.1
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• pp.24-33
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• 2013

We had analyzed 10 exome sequencing data and single nucleotide polymorphism chips for blood cancer provided by the PGM21 (The National Project for Personalized Genomic Medicine) Award program. We had removed sample G06 because the pair is not correct and G10 because of possible contamination. In-house software somatic copy-number and heterozygosity alteration estimation (SCHALE) was used to detect one loss of heterozygosity region in G05. We had discovered 27 functionally important mutations. Network and pathway analyses gave us clues that NPM1, GATA2, and CEBPA were major driver genes. By comparing with previous somatic mutation profiles, we had concluded that the provided data originated from acute myeloid leukemia. Protein structure modeling showed that somatic mutations in IDH2, RASGEF1B, and MSH4 can affect protein structures.

• 한국정보디스플레이학회:학술대회논문집
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• 2003.07a
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• pp.1081-1084
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• 2003

Structural morphology, annealing behavior and dielectric properties of polyaniline-emeraldine base (Pani-EB) and poly methyl methacrylate (PMMA) thin films prepared by spin coating technique have been studied. MIM and MISM structures were used to investigate annealing and dielectric behavior. The XRD and AFM spectrum of as grown and annealed thin films indicates the amorphous nature. The observed amorphous phase, low loss, dielectric behavior and thermal stability even at high temperatures implies the feasibility of utilizing PMMA and Pani-EB thin films as gate dielectric insulator layer in organic thin film transistors which can find application in flat panel display.

• Proceedings of the KIEE Conference
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• 1989.07a
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• pp.443-446
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• 1989

154kV insulator strings are frequently damaged by lightning strokes, overvoltage and contamination. And this insulator damage inflicts a loss on the power company. The purpose of this paper is to develop the arcing horn as a protective device of 154kV insulator strings against lightning flashover and overvoltages. So We have developed the arcing horn which is suitable for 154kV transmission line and estimated the performance of arcing horn by high current arcs and high voltage tests.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.8
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• pp.995-999
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• 2014

In this paper, a new size-reduction approach for branch-line coupler is introduced which uses parallel end-shorted coupled lines with lumped capacitors. The characteristic of the new design was analyzed using even-odd mode method, and simulated on HFSS before fabricated on the FR4 epoxy glass cloth copper-clad plat (CCL) PCB substrate at center frequency of 1 GHz. The electrical length of transmission line was reduced to 15 degrees, therefore the size of branch-line coupler was largely reduced approximately maintaining the same characteristic around the stable center frequency. The insertion loss of the branch-line coupler filter was -4.39 dB. The size of the overall hybrid is $20mm{\times}20mm$. Measurements results were well agreed with the simulated ones.

• Proceedings of the KIEE Conference
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• 1996.07c
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• pp.1828-1830
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• 1996

In this study, We developed the optical fiber incorporated high-voltage underground power cable which is combined optical fibers with conventional high-voltage underground power cable. Optical-Unit that optical fiber is inserted in stainless tube is tested, and we got good results enough to safe optical fibers. Also we put the optical fiber incorporated high-voltage underground power cable to the test of electrical characteristics and optical characteristics, we knew that the electrical characteristics were the same characteristics as conventional high-voltage underground power cable and the transmission loss change was almost zero.

• Proceedings of the KIEE Conference
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• 1997.11a
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• pp.52-54
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• 1997

This paper deals with investigating some characteristics of the inverter-driven tractive induction motor according to the various rotor slot number. 2-D time-stepped finite element method considering the inverter voltage waveform is utilized for electromagnetic field analysis. As a result, harmonics spectra of torque and bar loss are compared in each case.

• Proceedings of the KIEE Conference
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• 2015.07a
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• pp.820-821
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• 2015

본 논문에서는 영구자석형 기기의 RT(Real Time) 모델을 이용하여 실 제어상태의 PWM 스위칭 전류를 계산하고 철손과 회전자 영구자석의 손실을 현실적으로 해석하는 프로세스가 제시된다. 이러한 계산 프로세스는 전동기 구동 시스템의 실제 제어 환경과 전동기의 모델링을 고려하였다. 전동기 구동시스템의 모델링은 상용 소프트웨어인 MATLAB/Simulik 와 JMAG-RT 모델을 결합하여 구현되었으며, 전류 제어기의 PWM 스위칭 전류를 이용하여 영구자석 전동기의 철손이 계산되었다. 제안된 프로세스는 기 제작된 설계 모델을 대상으로 적용 타당성이 검증되었다.