• Journal of the Korean Electrochemical Society
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• v.21 no.3
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• pp.55-60
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• 2018

The demand for LIBs with higher energy densities has increased continuously because the emergence of wider and more challenging applications including HEV and EV has became imperative. However, in the case of anode material, graphite is insufficient to meet this need. To meet such demand, several type of negative electrode materials like silicon, tin, SiO, and transition metal oxide have been investigated for the advanced lithium secondary batteries. Recently, lithium vanadium oxide, which has a layered structure, is assumed as one of the promising anode material as alternative of graphite. This material shows a high volumetric capacity, which is 1.5 times higher than that of graphite. However, relative low electrical conductivity and particle fracture, which results in the electrolyte decomposition and loss of electric contact between electrode, induce rapid capacity decay. In this report, we investigated the effect of electrolyte additive on the electrochemical characteristics of lithium vanadium oxide.

• Journal of Microbiology and Biotechnology
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• v.30 no.3
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• pp.427-438
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• 2020

Middle East respiratory syndrome coronavirus (MERS-CoV) infects the lower respiratory airway of humans, leading to severe acute respiratory failure. Unlike human dipeptidyl peptidase 4 (hDPP4), a receptor for MERS-CoV, mouse DPP4 (mDPP4) failed to support MERS-CoV infection. Consequently, diverse transgenic mouse models expressing hDPP4 have been developed using diverse methods, although some models show no mortality and/or only transient and mild-to-moderate clinical signs following MERS-CoV infection. Additionally, overexpressed hDPP4 is associated with neurological complications and breeding difficulties in some transgenic mice, resulting in impeding further studies. Here, we generated stable hDPP4-transgenic mice that were sufficiently susceptible to MERS-CoV infection. The transgenic mice showed weight loss, decreased pulmonary function, and increased mortality with minimal perturbation of overexpressed hDPP4 after MERS-CoV infection. In addition, we observed histopathological signs indicative of progressive pulmonary fibrosis, including thickened alveolar septa, infiltration of inflammatory monocytes, and macrophage polarization as well as elevated expression of profibrotic molecules and acute inflammatory response in the lung of MERS-CoV-infected hDPP4-transgenic mice. Collectively, we suggest that this hDPP4-transgenic mouse is useful in understanding the pathogenesis of MERS-CoV infection and for antiviral research and vaccine development against the virus.

• Journal of Internet of Things and Convergence
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• v.6 no.1
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• pp.23-30
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• 2020

This paper proposes energy management directions to discover the factors of energy loss in homes and buildings and to find ways to improve them. We designed a diagnostic content app for everyday life so that not only housing experts but also the general public can use the detachable thermal imaging camera, which is a strong point of popularity and convenience. The diagnostic results using the app were analyzed using Energy Finder, an energy efficiency diagnostic solution. The survey was conducted on the senior center which is in the blind spots and facilities of the energy welfare area. The target of diagnosis was energy efficiency diagnosis by selecting 30 senior centers for over 15 years from 600 locations located in Naju City, Jeollanam-do. The overall diagnosis was good, but it is considered that the place classified as 7th grade needs to be supplemented to improve energy efficiency.

• Journal of the Korean Geotechnical Society
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• v.31 no.11
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• pp.49-60
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• 2015

Open-water sediment disposal has many applications in costal construction. Dumping of sediment in open water can be divided into descending stage under water and sedimentation stage on the seabed, and retained rate is evaluated from analyzed results of these two successive stages. Descending particle cloud have two distinct thermal and swam phase, and trajectory equations for each phase are derived to describe settling velocity and radius of particle cloud. For sedimentation stage, a numerical simulator is used to calculate growth factors for particle fiction angle and current velocity. Retained rate is defined as a mass rate of remained sediment inside the circle which has a center at dumping point on the sea level and user-defined effective radius. Retained rate map for Singapore coast is presented with water depth of 20 m, current velocity of 0.0~1.5 m/s, and effective radius of 5 m. It will decrease sediment mass loss during disposal operation and minimize surrounding environmental pollution.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.2
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• pp.308-315
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• 2001

In this paper, a new power amplifier is proposed for reduction of amplified RX band noise signals as well as intermodulation distortion signals using feedforward technique. This power amplifier is implemented for IMT-2000 basestation TX frequency band. Both TX band intermodulation distortion signals and RX band noise signals are reduced by controlling variable attenuator, phase shifter and error amplifier. The proposed power amplifier, which contains two loops-intermodulation distortion signals cancellation loop and RX band noise signals cancellation loop, can provide duplexer with low TX path insertion loss for various wireless communication systems due to choice of loose RX attenuation characteristic. The principle of the proposed amplifier is described graphically based on the conceptual schematic diagram. A two-tone test for power amplifier is done at 2.14GHz with frequency spacing of 5MHz, and RX band rejection test is done over RX full band of 60MHz with 1.95GHz center frequency. Experimental results represent that the cancellation performance of intermodulation distortion signals and RX band noise signals are more than 3 1dB and 21dB, respectively.

• International Journal of Quality Innovation
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• v.9 no.3
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• pp.71-91
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• 2008

The definition of cycle time is the time from the wafer start to the wafer output. It usually takes one or two months to get the product since customer decides to produce it. The cycle time is a critical factor for customer satisfaction because it represents the response time to the market. Long cycle time reflects the ineffective investment for the capital. The cycle time is very important for foundry because long cycle time will cause customer unsatisfied and the order loss. Consequently, all of the foundries put lots of human source in the cycle time improvement. Usually, we make decisions based on the experience in the cycle time management. We have no mechanism or theory for cycle time management. We do work-in-process (WIP) management based on turn rate and standard WIP (STD WIP) set by experiences. But the experience didn't mean the optimal solution, when the situation changed, the cycle time or the standard WIP will also be changed. The experience will not always be applicable. If we only have the experience and no mechanism, management will not be work out. After interview several foundry fab managers, all of the fab can't reflect the situation. That is, all of them will have an impact period after product mix or utilization varied. In this study, we want to develop a formula for standard WIP and use statistical process control (SPC) concept to set WIP upper/lower limit level. When WIP exceed the limit level, it will trigger action plans to compensate WIP Profile. If WIP Profile balances, we don't need too much WIP. So WIP level could be reduced and cycle time also could be reduced.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.11
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• pp.1294-1302
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• 2008

A design approach for a radiation element of dual polarization, which can be implemented in the waveguide structure, is proposed. For minimization of the radiating element, the ridged waveguide type is used and for dual polarization, the microstrip type of printed dipole structure is additionally installed inside the waveguide. In order to validate the design approach, $1{\times}4$ array antenna is fabricated and its performances such as return loss, co-polarization coupling between adjacent channels, and radiation patterns are investigated. Theory and experiment are observed to be in good agreement. The radiating structure is thought to be a useful one in an application to the phased array antenna system, in particular, requiring dual polarization characteristics.

• Journal of Advanced Marine Engineering and Technology
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• v.32 no.8
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• pp.1248-1256
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• 2008

In this paper, basic characteristics of transmission line employing PPGM (periodically perforated ground metal) were investigated using theoretical and experimental analysis.According to the results, unlike the conventional PBG (photonic band gap) structures, the characteristic impedance of the transmission line employing PPGM structure showed a real value, which exhibited a very small dependency on frequency. The transmission line employing PPGM structure showed a loss (per quarter wave length) higher by $0.1{\sim}0.2\;dB$ than the conventional microstrip line. According to the investigation of the dependency of RF characteristic on ground condition, the RF characteristic of the transmission line employing PPGM structure was hardly affected by the ground condition in the frequency lower than Ku band, but fairly affected in the frequency higher than Ku band, which indicated that coplanar waveguide employing PPGM structure was optimal for RF characteristic and reduction of size. Considering above results, impedance transformer was developed using coplanar waveguide with PPGM structure for the first time, and good RF characteristics were observed from the impedance transformer. In case that {\lambda}/4$ impedance transformer with a center frequency of 9 GHz was fabricated for a impedance transformation from 20 to10 {\Omega}$, the line width and length were 20 and $500\;{\mu}m$, respectively, and its size was only 0.64 % of the impedance transformer fabricated with conventional microstrip lines. Above results indicate that the transmission line employing PPGM is a promising candidate for a development of matching and passive elements on MMIC.

• The Journal of Korean Academy of Prosthodontics
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• v.36 no.1
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• pp.133-149
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• 1998

Clinical application of composite resin recently draw great concerns in dentistry. Especially due to advantages such as esthetics, adhesiveness, simple clinical procedures, various shapes and kinds of composite resins are widely being applied to prosthodontics, conservative dentistry, and orthodontics. But, clinical problems attributable to the polymerization shrinkage of composite resin have been proposed, and we have to regard clinical problems such as secondary caries, loss of restoration, fracture of the surrounding tooth structure, marginal discoloration, and tooth sensitivity, and many portions are remained to be overcome. Therefore, this study attempts to analyze stress distribution between resin and tooth structure which is generated during polymerization shrinkage of composite resin using three dimensional finite element method. Three dimensional finite element models with conventional box-shape cavity and erosion/abrasion type V-shape lesion cavity in upper central incisor were developed. These cavities were filled with four different types of placement techniques. (bulk filling, horizontal increment filling, oblique occlusal increment filling, oblique gingival increment filling) The stresses generated by polymerization shrinkage of composite resin were calculated. The results analyzed with three dimensional finite element method were as follows : 1. The increment filling technique showed the highest maximum normal stress in both conventional box-shape and V-shape cavities and showed a tendency to decrease after complete polymerization. 2. The bulk filling technique resulted in increased stresses during the curing process in both conventional box-shape and V-shape cavities and the highest maximum normal stress occurred after complete polymerization. 3. The bulk filling resulted in the lowest maximum normal stress in both box-shape and V-shape cavities 4. Regardless of placement method, in conventional box-shape cavity, the maximum normal stress increased in dentin floor, enamel, dentin sequence and in V-shape cavity, the maximum normal stress increased in enamel, dentin sequence.

• IMMUNE NETWORK
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• v.13 no.5
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• pp.213-217
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• 2013

Enterotoxigenic Bacteroides fragilis (ETBF) is a human gut commensal bacteria that causes inflammatory diarrhea and colitis. ETBF also promotes colorectal tumorigenesis in the Min mouse model. The key virulence factor is a secreted metalloprotease called B. fragilis toxin (BFT). BFT induces E-cadherin cleavage, cell rounding, activation of the ${\beta}$-catenin pathway and secretion of IL-8 in colonic epithelial cells. However, the precise mechanism by which these processes occur and how these processes are interrelated is still unclear. E-cadherin form homophilic interactions which tethers adjacent cells. Loss of E-cadherin results in detachment of adjacent cells. Prior studies have suggested that BFT induces IL-8 expression by inducing E-cadherin cleavage; cells that do not express E-cadherin do not secrete IL-8 in response to BFT. In the current study, we found that HT29/C1cells treated with dilute trypsin solution induced E-cadherin degradation and IL-8 secretion, consistent with the hypothesis that E-cadherin cleavage causes IL-8 secretion. However, physical damage to the cell monolayer did not induce IL-8 secretion. We also show that EDTA-mediated disruption of E-cadherin interactions without E-cadherin degradation was sufficient to induce IL-8 secretion. Finally, we determined that HT29/C1 cells treated with LiCl (${\beta}$-catenin activator) induced IL-8 secretion in a dose-dependent and time-dependent manner. Taken together, our results suggest that BFT induced IL-8 secretion may occur by the following process: E-cadherin cleavage, disruption of cellular interactions, activation of the ${\beta}$-catenin pathway and IL-8 expression. However, we further propose that E-cadherin cleavage per se may not be required for BFT induced IL-8 secretion.