• Toxicological Research
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• 제30권4호
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• pp.235-242
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• 2014

Cancer cells are known to drastically alter cellular energy metabolism. The Warburg effect has been known for over 80 years as pertaining cancer-specific aerobic glycolysis. As underlying molecular mechanisms are elucidated so that cancer cells alter the cellular energy metabolism for their advantage, the significance of the modulation of metabolic profiles is gaining attention. Now, metabolic reprogramming is becoming an emerging hallmark of cancer. Therapeutic agents that target cancer energy metabolism are under intensive investigation, but these investigations are mostly focused on the cytosolic glycolytic processes. Although mitochondrial oxidative phosphorylation is an integral part of cellular energy metabolism, until recently, it has been regarded as an auxiliary to cytosolic glycolytic processes in cancer energy metabolism. In this review, we will discuss the importance of mitochondrial respiration in the metabolic reprogramming of cancer, in addition to discussing the justification for using mitochondrial DNA somatic mutation as metabolic determinants for cancer sensitivity in glucose limitation.

• Journal of Radiation Protection and Research
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• 제41권3호
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• pp.206-210
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• 2016

Background: Ionizing radiation causes cellular damage and death through the direct damage and/or indirectly the production of ROS, which induces oxidative stress. This study was designed to evaluate the in vivo radioprotective effects of a bio-active material coated fabric (BMCF) against ${\gamma}$-irradiation-induced cellular damage in Sprague-Dawley (SD) rats. Materials and Methods: Healthy male SD rats wore bio-active material coated (concentrations in 10% and 30%) fabric for 7 days after 3 Gy of ${\gamma}$-irradiation. Radioprotective effects were evaluated by performing various biochemical assays including spleen and thymus index, WBC count, hepatic damage marker enzymes [aspartate transaminase (AST) and alanine transaminase (ALT)] in plasma, liver antioxidant enzymes, and mitochondrial activity in muscle. Results and Discussions: Exposure to ${\gamma}$-irradiation resulted in hepatocellular and immune systemic damage. Gamma-irradiation induced decreases in antioxidant enzymes. However, wearing the BMCF-30% decreased significantly AST and ALT activities in plasma. Furthermore, wearing the BMCF-30% increased SOD (superoxide dismutase) and mitochondrial activity. Conclusion: These results suggest that wearing BMCF offers effective radioprotection against ${\gamma}$-irradiation-induced cellular damage in SD rats.

• 한국정보통신학회논문지
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• 제19권1호
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• pp.91-96
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• 2015

이종의 셀룰러 망은 다양한 무선 환경에서의 이동 단말 서비스를 지원한다. 최근 셀룰러 망에서는 음성 서비스 및 데이터 서비스의 요구가 폭발적으로 증가하고 있는 추세로 기술적 기반이 LTE-A (Long-Term Evolution Advanced)와 IEEE 802.16m 무선망으로 전환되어 보다 많은 수의 기지국 서비스 지원을 필요로 하게 되었다. 셀룰러 망에서의 전력 수요는 대부분 기지국에서 소모되며 이에 기지국의 에너지 소모의 절감이 요구되고 있는 시점이다. 본 논문에서는 동적인 전력 관리 방안을 기반으로 기지국의 전력 소비를 줄이는 방안을 제안한다. 본 논문에서는 시뮬레이션을 통하여 저전력 기지국 수행을 위한 핸드오버 방식의 성능 분석을 수행한다.

• Composites Research
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• 제22권4호
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• pp.27-32
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• 2009

본 연구에서는 충돌속도가 다르지만, 총 충돌에너지는 동일하게 유지한 상태에서 충돌을 가했을 때 발포 고분자의 응력-변형률 관계와 충돌에너지 흡수 특성에 관하여 고찰하였다. 이는 충돌시 관성과 변형률 속도에 변화를 주어 재료의 반응거동 및 특성을 파악하기 위함이다. 두가지 다른 밀도(64 $kg/m^3$, 89 $kg/m^3$)를 갖는 발포고분자시편에 대한 준정적시험과 충돌시험이 수행되었다. 또한 Sherwood-Frost 모델과 임펄스 모멘텀 이론의 두가지가 연성된 방정식을이용하여 발포고분자의 구성방정식으로 제안하였다.\ 제안된 구성방정식을 이용하여, 응력변형률 선도를 구하고, 충돌시험결과와 비교하여, 본 구성방정식이 우수하게 결과를 예측할 수 있는 것으로 나타났다.

• Journal of Communications and Networks
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• 제12권2호
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• pp.114-121
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• 2010

In this paper, an auctioning strategy is proposed for cellular networks that ensures net energy savings. The pricing scheme, in conjunction with a two dimensional bid structure, incentivizes cooperation at the terminal nodes for better interference management at receivers and for cooperative relaying. It is shown that, for the proposed auctioning strategy, network operators are guaranteed revenue gains, mobile nodes' dominant strategy is to bid their true valuation of their energy resources, and overall effective energy gains occur under the assumption of a reserve price for bidding. Simulation results show that significant energy savings can be achieved by employing this auctioning mechanism for a 3G cellular set-up.

• Integrative Medicine Research
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• 제6권3호
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• pp.254-259
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• 2017

Background: Those classified as Tae-Eum (TE)-type people in Sasang constitutional medicine (SCM) are prone to obesity. Although extensive clinical observations have confirmed this tendency, the underlying physiological mechanisms are unknown. Here, we propose a novel hypothesis using integrative physiology to explain this phenomenon. Methods: Hypoactive lung function in the TE type indicates that respiration is attenuated at the cellular level - specifically, mitochondrial oxygen consumption. Because a functional reduction in cellular energy metabolism is suggestive of intrinsic hypoactivity in the consumption (or production) of metabolic energy, we reasoned that this tendency can readily cause weight gain via an increase in anabolism. Thus, this relationship can be derived from the graph of cellular metabolic power plotted against body weight. We analyzed the clinical data of 548 individuals to test this hypothesis. Results: The statistical analysis revealed that the cellular metabolic rate was lower in TEtype individuals and that their percentage of obesity (body mass index >25) was significantly higher compared to other constitutional groups. Conclusion: Lower cellular metabolic power can be an explanation for the obesity trend in TE type people.

• Journal of Communications and Networks
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• 제18권6호
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• pp.926-937
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• 2016

In this paper, we study the feasibility of receiver diversity for application to downlink cellular networks, where low-energy devices are equipped with information decoding and energy harvesting receivers for simultaneous wireless information and power transfer. We compare several options that are based on selection combining and maximum ratio combining, which provide different implementation complexities. By capitalizing on the Frechet inequality, we shed light on the advantages and limitations of each scheme as a function of the transmission rate and harvested power that need to be fulfilled at the low-energy devices. Our analysis shows that no scheme outperforms the others for every system setup. It suggests, on the other hand, that the low-energy devices need to operate in an adaptive fashion, by choosing the receiver diversity scheme as a function of the imposed requirements. With the aid of stochastic geometry, we introduce mathematical frameworks for system-level analysis. We show that they constitute an important tool for system-level optimization and, in particular, for identifying the diversity scheme that optimizes wireless information and power transmission as a function of a sensible set of parameters. Monte Carlo simulations are used to validate our findings and to illustrate the trade-off that emerge in cellular networks with simultaneous wireless information and power transfer.

• 한국전기전자재료학회논문지
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• 제17권9호
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• pp.936-941
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• 2004

In recent years, the rapid growth of portable electronic devices requires the high-energy density characteristics of batteries. Zinc air batteries have specific capacity as high as 820mAh/g. However, Zinc air batteries used for hearing aid applications only so far, because the atmosphere could affect it, and it has weakness in the rate capability. However, recent developments of electrode manufacturing technologies made us to overcome that weakness. And the efforts of applying zinc air batteries to portable electronic devices, especially in cellular phone application have been increased. In this paper, the effects of conducting material and polymer binder in cathode on the electrochemical characteristics were investigated. Our research team succeeded in producing 2.4Ah class zinc air battery for cellular phone application. Its volumetric energy density was 920 wh/l, and gravimetric energy density was 308 wh/kg. The volumetric energy density of our zinc air battery is two times higher than one of lithium secondary battery, and three times higher than that of alkaline manganese battery.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권4호
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• pp.1249-1265
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• 2022

Video streaming has become one of the most popular applications for mobile devices. The network bandwidth required for video streaming continues to exponentially increase as video quality increases and the user base grows. Multi-Path TCP (MPTCP), which allows devices to communicate simultaneously through multiple network interfaces, is one of the solutions for providing robust and reliable streaming of such high-definition video. However, mobile video streaming over MPTCP raises new concerns, e.g., power consumption and cellular data usage, since mobile device resources are constrained, and users prefer to minimize such costs. In this work, we propose a mobile video streaming framework over MPTCP (mDASH) to reduce the costs of energy and cellular data usage while preserving feasible streaming quality. Our evaluation results show that by utilizing knowledge about video behavior, mDASH can reduce energy consumption by up to around 20%, and cellular usage by 15% points, with minimal quality degradation.

• ETRI Journal
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• 제44권1호
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• pp.155-167
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• 2022

The Internet of Things (IoT) is a new paradigm that connects physical and virtual objects from various domains such as home automation, industrial processes, human health, and monitoring. IoT sensors receive information from their environment and forward it to their neighboring nodes. However, the large amounts of exchanged data are vulnerable to attacks that reduce the network performance. Most of the previous security methods for IoT have neglected the energy consumption of IoT, thereby affecting the performance and reducing the network lifetime. This paper presents a new multistep routing protocol based on cellular learning automata. The network lifetime is improved by a performance-based adaptive reward and fine parameters. Nodes can vote on the reliability of their neighbors, achieving network reliability and a reasonable level of security. Overall, the proposed method balances the security and reliability with the energy consumption of the network.