• Annals of Occupational and Environmental Medicine
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• v.35
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• pp.12.1-12.12
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• 2023

Background: The purpose of this study is to investigate the relationship between job stress and impaired fasting glycemia (IFG) of male workers in a manufacturing industry. Methods: Data were collected from 5,886 male workers in a manufacturing industry who participated in the medical examination from June 19 to August 14, 2020 through self-reported questionnaires. The general characteristics of the subjects, shift work, high blood pressure, dyslipidemia, and job stress were included. Job stress was measured using the Korean Occupational Stress Scale (KOSS) consisting of 8 items and 43 questions. Multivariable logistic regression analysis was used to investigate the IFG association with job stress. Results: Among the various factors that can cause job stress, only high job demand was associated with a risk of IFG (odds ratio, 1.43; 95% confidence interval, 1.13-1.82) especially in non-shift worker. For all other factors, no statistically significant results were obtained. Conclusions: In this study of male workers engaged in the Korean steel manufacturing industry, the 'job demand' item among job stress of non-shift worker was related to IFG.

• Korean journal of food and cookery science
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• v.22 no.6 s.96
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• pp.783-791
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• 2006

The consciousness and eating habits of the housekeeper directly influence the stress level and health quality of the household occupants. In Korea, most housewives are in charge of dietary life. Accordingly, their attitudinal clusters toward dietary (eating) life were researched in relation to their stress and health. The research results showed that irregular eating habits cause stress. Therefore, it is necessary for housewives to have a regular eating habit. The results were as follows. The house wives' attitudes toward dietary life were categorized into 5 clusters: regular and speedy overeating, regular and frequent eating, regular and light eating, irregular and light eating, irregular and speedy overeating. The cluster of regular and frequent snacks was 24.3%. The cluster of irregular and speedy overeating caused the most stress. Especially the house wives' group belonging to the cluster of irregular and speedy overeating were under social and emotional stress, while the cluster of regular and light eating and the cluster of irregular and light eating were under concentration stress. The cluster of regular and frequent snacks and the cluster of irregular and light eating had negative effect on their health, while the cluster of regular and speedy overeating had negative effect on their family's health by their social stress.

• Journal of Technologic Dentistry
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• v.31 no.1
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• pp.7-15
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• 2009

Purpose: This study was to propose the clear understanding for stress distribution of supporting bone by use of staggered buccal offset tripodal placement of fixtures of posterior 3 crown implant partial dentures. We realized posterior 3 crown implant fixed partial dentures through finite element modeling and analysed stress effect of implant arrangement location to supporting bone under external load using finite element method. Method: To understand stress distribution of 3 crown implant fixed partial dentures which have 2 different arrangement by finite element analysis. In each model, for loading condition, we applied $45^{\circ}$ oblique load to occlusal surface of crown and applied 100 N for 3 crown individually(total 300 N) for imitating possible oral loading condition. at this time, we calculated Von Mises stress distribution in supporting bone through finite element method. Result: When apply $45^{\circ}$ oblique load to in-line arrangement model, maximum stress result for 100 N for each 3 crown 47.566MPa. In tripodal placement, result for 1mm buccal offset tripodal placement implant model was maximum distributed load 51.418MPa, so result was higher than in-line arrangement model. Conclusion: In stress distribution result by placement of implant fixture, the most effective structure was in-line arrangement. The tripodal placement does not effective for stress distribution, gap cause more damage to supporting bone.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.2
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• pp.115-119
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• 2016

Winding is one of the major processes in roll-to-roll systems. Taper tension profile in a winding determines the distribution of stress in the radial direction, i.e., the radial stress in the wound rolls. Maximum radial stress is major cause of material defect, and this study has been actively proceeded. Traditional models of radial stress model were focused on flexible and light substrate. In this study, we developed an advanced radial stress model including effects of both these parameters(weight and stiffness) on the radial stress. The accuracy of the developed model was verified through FEM(Finite Element Method) analysis. FEM result of maximum radial stress value corresponds to 99 % in comparison to result with the model. From this study, the material defects does not occur when the steel winding. And steel industry can be applied to improve the winding process.

• International Journal of Molecular Medicine
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• v.44 no.1
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• pp.125-134
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• 2019

Mutations in myelin protein zero (MPZ) cause inherited peripheral neuropathies, including Charcot-Marie-Tooth disease (CMT) and Dejerine-Sottas neuropathy. Mutant MPZ proteins have previously been reported to cause CMT via enhanced endoplasmic reticulum (ER) stress and Schwann cell (SC) death, although the pathological mechanisms have not yet been elucidated. In this study, we generated an in vitro model of rat SCs expressing mutant MPZ (MPZ V169fs or R98C) proteins and validated the increase in cell death and ER stress induced by the overexpression of the MPZ mutants. Using this model, we examined the efficacy of 3 different aminosalicylic acids (ASAs; 4-ASA, sodium 4-ASA and 5-ASA) in alleviating pathological phenotypes. FACS analysis indicated that the number of apoptotic rat SCs, RT4 cells, induced by mutant MPZ overexpression was significantly reduced following treatment with each ASA. In particular, treatment with 4-ASA reduced the levels of ER stress markers in RT4 cells induced by V169fs MPZ mutant overexpression and relieved the retention of V169fs mutant proteins in the ER. Additionally, the level of an apoptotic signal mediator (p-JNK) was only decreased in the RT4 cells expressing R98C MPZ mutant protein following treatment with 4-ASA. Although 4-ASA is known as a free radical scavenger, treatment with 4-ASA in the in vitro model did not moderate the level of reactive oxygen species, which was elevated by the expression of mutant MPZ proteins. On the whole, the findings of this study indicate that treatment with 4-ASA reduced the ER stress and SC death caused by 2 different MPZ mutants and suggest that ASA may be a potential therapeutic agent for CMT.

• Structural Engineering and Mechanics
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• v.52 no.1
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• pp.89-95
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• 2014

We analyze the buckling of a thin elastic plate due to intrinsic stresses in thin films attached to the surfaces of the plate. In the case of cylindrical buckling, it is shown that for a plate with clamped edges compressive intrinsic film stresses can cause flexural buckling of the plate, while tensile intrinsic film stresses cannot. For a plate with free edges, film intrinsic stresses, compressive or tensile, cannot cause buckling.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.317.2-317.2
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• 2002

Peroxynitrite, formed from the reaction of .O2- and .NO, is a cytotoxic species that can oxidize several cellular components such as proteins. lipids and DNA. Oxidative stress is considered to be the major cause of aging and many age-related diseases including Alzheimer's disease. rheumatoid arthritis. cancer. and atherosclerosis. ONO-, a powerful oxidant, can cause damage of proteins, lipid and DNA through nitration and oxidation. (omitted)

• Nutrition Research and Practice
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• v.18 no.4
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• pp.464-478
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• 2024

BACKGROUND/OBJECTIVES: Chronic alcohol consumption causes oxidative stress in the body, which may accumulate excessively and cause a decline in memory; problem-solving, learning, and exercise abilities; and permanent damage to brain structure and function. Consequently, chronic alcohol consumption can cause alcohol-related diseases. MATERIALS/METHODS: In this study, the protective effects of Phyllostachys edulis (Carrière) J. Houz (PE) against alcohol-induced neuroinflammation and cognitive impairment were evaluated using a mouse model. Alcohol (16%, 5 g/kg/day for 6 weeks) and PE (100, 250, and 500 mg/kg/day for 21 days) were administered intragastrically to mice. RESULTS: PE showed a protective effect against memory deficits and cognitive dysfunction caused by alcohol consumption, confirmed through behavioral tests such as the T-maze, object recognition, and Morris water maze tests. Additionally, PE attenuated oxidative stress by reducing lipid oxidation, nitric oxide, and reactive oxygen species levels in the mice's brains, livers, and kidneys. Improvement of neurotrophic factors and downregulation of apoptosis-related proteins were confirmed in the brains of mice fed low and medium concentrations of PE. Additionally, expression of antioxidant enzyme-related proteins GPx-1 and SOD-1 was enhanced in the liver of PE-treated mice, related to their inhibitory effect on oxidative stress. CONCLUSION: This suggests that PE has both neuroregenerative and antioxidant effects. Collectively, these behavioral and histological results confirmed that PE could improve alcohol-induced cognitive deficits through brain neurotrophic and apoptosis protection and modulation of oxidative stress.

• Environmental Analysis Health and Toxicology
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• v.26
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• pp.9.1-9.9
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• 2011

Objectives: In order to evaluate which temperature index is the best predictor for the health impact assessment of heat stress in Korea, several indexes were compared. Methods: We adopted temperature, perceived temperature (PT), and apparent temperature (AT), as a heat stress index, and changes in the risk of death for Seoul and Daegu were estimated with $^1{\circ}C$ increases in those temperature indexes using generalized additive model (GAM) adjusted for the non-temperature related factors: time trends, seasonality, and air pollution. The estimated excess mortality and Akaike's Information Criterion (AIC) due to the increased temperature indexes for the $75^{th}$ percentile in the summers from 2001 to 2008 were compared and analyzed to define the best predictor. Results: For Seoul, all-cause mortality presented the highest percent increase (2.99% [95% CI, 2.43 to 3.54%]) in maximum temperature while AIC showed the lowest value when the all-cause daily death counts were fitted with the maximum PT for the $75^{th}$ percentile of summer. For Daegu, all-cause mortality presented the greatest percent increase (3.52% [95% CI, 2.23 to 4.80%]) in minimum temperature and AIC showed the lowest value in maximum temperature. No lag effect was found in the association between temperature and mortality for Seoul, whereas for Daegu one-day lag effect was noted. Conclusions: There was no one temperature measure that was superior to the others in summer. To adopt an appropriate temperature index, regional meteorological characteristics and the disease status of population should be considered.

• Journal of muscle and joint health
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• v.3 no.2
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• pp.151-165
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• 1996

The purpose of this study is to describe the acknowledgement of the cause of the illness in the patients with RA. I used naturalistic inquiry as a research methodology. The purposive sampling was conducted. 23 subjects who experienced RA, lived in middle-sized city in Korea, and 19 women and 4 men. I collected data using indepth structured interview, "What is the acknowledgement of the cause of the illness?" I used inductive data analysis-such as unitizing and categorizing. This process is used constant comparative method. Summerising the results of this study, the acknowledgement of the cause of the illness are composed of physical constitution, fatalism, the attribution of physical overload, the attribution of stress, the lack of nutrition. The factors which affect the acknowledgement of the cause of the illness are composed of internal factors, external factors, environmental factors. The internal factors are the weakness of the childhood, the illness experience in the family members, juvenile rheumatoid arthritis, personality, lack of nutrition. The external factors are pregnancy, delivery, role burden and conflict, economic problem. The environmental factors are humid condition, abrupt environmental change. It is needed to explaine the coping pattern according to the acknowledgement of the cause of the illness in the next research.