• Transactions of Materials Processing
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• v.8 no.1
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• pp.101-107
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• 1999

The upset forging stage is the initial work in the forging process. It is used to remove the segregation and cavities of the ingot. Specially in handling large sized ingot, an improper upset forging can cause serious surface tearing. However, there is no detail reference for stable upset forging work. To resolve this difficulty, we studied several factors such as upset forging time, temperature varation of ingot, damage, load and stain rate etc., by using the rigid-plastic finite element approach available in the DEFORM code. Numerical simulation results indicated that: the load value of upset forging works shows severe decreasing trend at a certain point, same as strain rate. Also defects were found to be concentrated around the upper and lower portions of the ingot. With these results, we can estimate a guideline for stable upset forging work.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1999.04a
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• pp.343-350
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• 1999

Orthotropic steel bridge decks are potentially liable to cause fatigue cracks due to weld defects, residual stresses, and in-plane or out-of-plane stresses. In particular, the cracks propagated through deckplate in longitudinal rib to deckplate joints occur at weld toe and weld root due to stress concentrations. Numerical parametric studies are performed to show the Influence of the parameters on the stress concentration at the connection between the longitudinal rib and the deckplate. The parameters include root gap, toe angle $\theta$, toe radius $\rho$, and weld penetration. This study provides a fundamental point for the improvement of fatigue resistance and the estimation of the fatigue crack propagation in wekded joint details.

• Journal of Chest Surgery
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• v.28 no.4
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• pp.340-345
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• 1995

Between 1983 and 1993, 250 patients over 16 years of age who had undergone a surgical correction of a congenital cardiovascular disease were reviewed. 222 patients were divided into acyanotic group and 28 patients were cyanotic group. The most common defects were atrial septal defect [96 patients and ventricular septal defect [95 patients . There were 128 patients in the third decade, 71 patients under 20 years of age, 40 patients in the fourth decade and 11 patients over 40 years of age. The male to female ratio was 1.05:1. Operative mortality was 6.8% [4.1% in the acyanotic group and 26.8% in the cyanotic group and the most common cause of death was low cardiac output syndrome.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.963-968
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• 2003

The continuous process systems usually consists of various components: driven rollers. idle rolls, load-cell and so on. Even a simple fault in a single component in the line may cause a catastrophic damage on the final products. Therefore it is absolutely necessary to diagnosis the components of the continuous systems. In this paper, an adaptive eccentricity compensation method is presented. And a new diagnosis method for transverse roll shape defects on rolling process is developed. The new method was induced from analyzing the rolling mechanism by using rolling force model, tension model, Hitchcock's equation, and measured delivery thickness of materials etc. Computer simulation results also show that the proposed diagnosis methods is very effective in the diagnosis of 3-D roll shape

• Journal of the Korea Safety Management & Science
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• v.16 no.1
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• pp.139-146
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• 2014

As Crosby notes, the most companies spend 15 to 20% of their sales dollars on quality costs. Generally the most effective way to manage quality costs is to avoid having defects in the first place. In this paper we have studied about the repair(service) problem of domestic gas boiler within warranty period. We develop a system, which man could find the cause of the problem at an early stage and could devise a countermove to the problem under supposing that the service(repair) rate follows exponential distribution and the product is manufactured lot-for-lot continually. Using the developed early sensing system. it is expected to improve the reliability of the product, to save expenses of company and to improve customer's satisfaction. And the system will be expended to incorporate information technology, which can detect the repair rate automatically.

• Transactions of Materials Processing
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• v.15 no.8 s.89
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• pp.539-543
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• 2006

Experimental studies are carried out in order to investigate the effects of heat treatment on the surface machined by W-EDM. In this work, two ways of heat treatment after W-EDM are considered. As a comparison, the machined surface by a traditional method such as milling/grinding is also considered. Thereby, specimens are prepared by four different machining methods. Those are (1) milling and then grinding, (2) wire-cut electric discharge machining (W-EDM), and (3) low temperature heat treatment or (4) high temperature heat treatment after W-EDM. The resulting surface roughness are measured and the changes of surface microstructures are investigated using the scanning electron microscope (SEM) with energy dispersive X-ray spectrometer (EDS). In general, heat treatment after W-EDM result in smoother surface and better chemical composition at the machined surface. Especially, high temperature tempering could remove defects in the thermally affected zone, which cause an overall deterioration of the surface machined by W-EDM.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.1209-1210
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• 2008

According to previous report, aged sleeves for old transmission lines have variable defects such as biased installed case or corrosion of steel sleeve. Biased installed sleeve occupied 20 percent among the investigated aged sleeves. This defect must cause local heating of splice connector and limit power transmission capacity. It even inspire falling out of overhead conductor from sleeves. This paper studies thermal properties and tension for ACSR conductor in case of biased installed sleeve model. The detailed results were presented in the text.

• Interdisciplinary Bio Central
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• v.3 no.4
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• pp.16.1-16.8
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• 2011

Defects in mitochondrial DNA (mtDNA) cause many human diseases and are critical factors that contribute to aging. The mechanisms of maternally-inherited mtDNA mutations are well studied. However, the role of acquired mutations during the aging process is still poorly understood. The most plausible mechanism is that increased reactive oxygen species (ROS) may affect the opening of mitochondrial voltage dependent anion channel (VDAC) and thus results in damage to mtDNA. This review focuses on recent trends in mtDNA research and the mutations that appear to be associated with increased ROS.

• Proceedings of the KSME Conference
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• 2008.11b
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• pp.2410-2414
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• 2008

Human heart valves diseased by congenital heart defects, rheumatic fever, bacterial infection, cancer may cause stenosis or insufficiency in the valves. Treatment may be with medication but often involves valve repair or replacement (insertion of an artificial heart valve). Bileaflet mechanical heart valves (BMHVs) are widely implanted to replace the diseased heart valves, but still suffer from complications such as hemolysis, platelet activation, tissue overgrowth and device failure. These complications are closely related to both flow characteristics through the valves and leaflet dynamics. In this study, the physiological flow interacting with the moving leaflets in a bileaflet mechanical heart valve (BMHV) is simulated with a strongly coupled implicit fluid-structure interaction (FSI) method which is newly organized based on the Arbitrary-Lagrangian-Eulerian (ALE) approach and the dynamic mesh method (remeshing) in FLUENT. The simulated results are in good agreement with previous experimental studies. This study shows the applicability of the present FSI model to the complicated physics interacting between fluid flow and moving boundary.

• Journal of Interdisciplinary Genomics
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• v.5 no.2
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• pp.29-31
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• 2023

Pseudohypoparathyroidism (PHP) is very rare and shows heterogeneity with impaired genetic components. PHP is characterized by parathyroid hormone resistance to target organ, related with a GNAS (guanine nucleotide-binding protein α-subunit) mutation and epimutation. PHP receptor is coupled with the stimulatory G protein which activates cyclic adenosine monophosphate formation. PHP type 1A is caused by inactivating mutations on the maternal allele of the GNAS whereas paternal allele mutations cause pseudopseudohypoparathyroidism. PHP type 1B is caused by abnormal patterns of methylation in differentially methylated region which can be divided into partial or complete. This disease has some difficulties to diagnose according to these different molecular alterations caused by complex genetic and epigenetic defects. According to this different molecular alterations, genetic confirmation must be done to discriminate their etiology.